Researchers at Rice University have developed an energy landscape model that details the combination of forces driving nuclear motion in cells. The model, based on a protein folding algorithm, reveals the presence of dynamically associated domains and phase separation in chromatin segments.
Graphene's lifetime limitation has been overcome by connecting it to other atomic layers. The tri-layer material increases the lifetime of excited electrons in graphene by several hundred times, enabling high efficiency in solar cells. This breakthrough could lead to the development of ultrathin and flexible solar cells.
A virtual reality simulation of Albert Einstein's body reduces age stereotypes and enhances cognitive performance in those with low self-esteem. Participants with low self-esteem who experienced the virtual Einstein body performed better on cognitive tasks and showed reduced implicit bias against older people.
A recent study by Nick Nidzieko reveals that larger estuarine systems are less productive per unit size than smaller ones, challenging the long-held 'larger-is-more-efficient' concept. This finding has significant implications for understanding carbon and nutrient cycling in coastal zones.
A study by King's College London found that babies introduced to solid foods early slept longer and woke less frequently at night compared to those exclusively breastfed for six months. This research challenges current government advice, which states that starting solid foods won't make babies more likely to sleep through the night.
University of Illinois researchers found that dry-milling process removes majority of phenolics from corn kernels. Despite this, heat can release bound forms of compounds and improve antioxidant content in corn-based foods.
A new study by researchers at the University of Maryland School of Medicine found that exposing newborn mice to vaginal microbes from stressed female mice can transfer the effects of stress to the newborns. The study indicates that maternal stress affects brain development in offspring and may be influenced by the vaginal microbiota.
A team at the University of California San Diego has developed a wireless chip that can detect genetic mutations, including single nucleotide polymorphisms (SNPs), in real-time. The chip is at least 1,000 times more sensitive than current technology and could lead to cheaper, faster, and portable biosensors for early disease detection.
Research shows that ambient temperature before conception influences offspring's brown adipose tissue activity and protection against excess weight and metabolic disorders. This epigenetic mechanism may explain why people in cold regions have higher levels of brown fat.
Researchers found that mitochondrial DNA in exosomes triggers an antiviral genetic program, protecting against viral infection. Exosomes produced by T lymphocytes are taken up by dendritic cells via intercellular contacts and trigger alterations in gene expression.
A comparative study found that rats use a different approach to solve visual discrimination tasks compared to shrews, monkeys, and humans. Researchers suggest that this difference may indicate distinct brain function in rats.
A recent study published in Eurosurveillance confirms that NDM bacteria can be transmitted between dogs and humans, with the owner of two Finnish dogs also carrying the bacterium. The transmission was established through genome analysis, which revealed identical bacterial isolates from dogs and humans.
Healthcare leaders call on the UK government to lift restrictions on taking abortion pills at home, citing improved access for vulnerable women. The move would align with Scotland and Wales' existing policies and reduce unnecessary clinic visits, bettering women's dignity and wellbeing.
Insectivorous birds consume between 400 and 500 million metric tonnes of insects per year, mainly beetles, flies, and other arthropods. This helps keep plant-eating insect populations under control, supporting forest ecosystems.
A study published in BMC Evolutionary Biology found that Bale monkeys living in different habitats have distinct mitochondrial DNA profiles. The researchers discovered that populations from fragmented forests were more closely related to vervet and grivet monkeys than those from continuous forests, suggesting hybridization had occurred.
Researchers identify myofibroblasts as key players in activating nucleus movement, potentially leading to new therapeutic strategies for muscle disorders. The discovery could improve understanding of muscle differentiation, functionality, and regeneration.
A study by UCSF researchers found that hospitals adopting electronic health records (EHRs) initially experienced higher mortality rates, but these improved over time as they learned to work with the technology and adopted new capabilities. The benefits of EHR adoption were most pronounced in smaller and non-teaching hospitals.
A new study estimates that implementing national food policies in schools could lead to a 17-25% increase in fruit consumption, a 15-27% decrease in sugary drink consumption, and a significant impact on long-term health outcomes. The policies are expected to prevent thousands of deaths per year.
Researchers are investigating the relationship between obesity-induced changes in fat tissue metabolism and vascular disease. The study aims to characterize the role of protein FSP27 in the pathogenesis of obesity-related vascular disease.
Researchers found that stronger westerly winds near Antarctica led to massive CO2 releases in the past, similar to current human-caused climate change. This contraction and strengthening of winds can significantly impact atmospheric CO2 concentrations and future climate.
Research shows patients are more likely to fill prescriptions when they pay less for high-value medications, which can prevent costly health issues. This approach, called value-based insurance design, also leads to decreased spending elsewhere in the healthcare system.
Tropical Storm Chris strengthened off the Carolina coast after passing over NASA's Aqua satellite on July 9. The storm showed signs of heavy rainfall potential due to cold cloud top temperatures as low as minus 63 degrees Fahrenheit.
Researchers discovered a llama-derived nanobody that specifically targets G beta-gamma signaling, preventing it from activating several other signaling proteins. This approach may provide control over multiple GPCRs and avoid undesired cellular events.
A human clinical trial revealed verapamil as a safe and effective therapy to reduce insulin requirements and hypoglycemic episodes in adult subjects with recent onset Type 1 diabetes. The study found that regular oral administration of verapamil enabled patients to produce higher levels of their own insulin.
Researchers found that even mild COPD patients have lost over 40% of their small airways, suggesting early intervention is crucial. The study's findings could lead to the development of new drugs to treat patients with COPD at earlier stages.
Researchers found that focusing on impact uncertainty leads participants to adopt behaviors that preserve others' welfare, whereas outcome uncertainty activates self-focused narratives that enable selfish behavior. This discovery has implications for public health messaging and policy-making.
A new patch developed at Washington University in St. Louis increases fluorescence intensity by 100 times, making it easier to visualize and diagnose low-abundance analytes. The plasmonic patch is a cheap fix that can be applied to existing diagnostic tests without requiring any protocol changes.
A team of leukemia scientists has discovered how to predict healthy individuals at risk of developing acute myeloid leukemia (AML) by identifying genetic mutations in their blood. By analyzing data from a large population health study, the researchers found that people with early mutations are more likely to develop AML.
Researchers at Boston Children's Hospital have discovered a new way to enhance the immune system's tolerance for organ transplants. By increasing the activity of a regulatory protein called DEPTOR in immune cells, heart transplants were able to survive for an average of 35 days, compared to just 7 days without immunosuppressive drugs.
Researchers at the University of Adelaide found that fish alter their cropping practices under high CO2 conditions, leading to faster growth rates of algae and increased territory occupation. This adaptation could benefit fisheries stocks.
Researchers have identified 52 distinct cell types in lung tumors, far more than previously thought, offering new avenues for treatment and research. The study's findings will help develop strategies to fight tumor growth and test new immunotherapy targets.
The Finnish opera scene is experiencing a surge in diversity and creativity, thanks to its emphasis on equality and inclusivity. Over 300 operas have been composed in Finland between 1990 and 2017, with the number of new works increasing significantly in the 21st century.
Researchers discovered that pancreatic cancer cells' ability to alter their characteristics and shape affects where metastases form. The presence of E-cadherin protein controls this process, with its absence leading to lung metastases but not liver metastases.
Researchers at University of Nottingham develop rechargeable battery using salt that lasts longer and holds more power. The new battery design has the potential for grid-scale renewable energy storage and could also store solar heat.
A new study found that one in four working-age adults with type 1 diabetes experienced at least one gap of 30 days or more in their private health insurance, leading to a five-fold increase in emergency room visits and hospital stays. The gaps resulted in higher blood sugar levels and decreased satisfaction with life.
The US refugee resettlement program is struggling to cope with a changing sociopolitical climate, particularly with regards to Syrians. Researchers found that organizations are struggling to obtain basic resources for refugees upon arrival, including housing and job placement.
Astronomers have found a quasar with the brightest radio emission ever observed in the early universe, providing unprecedented insight into the universe's youth. The discovery allows researchers to study the early galaxy formation process, which is crucial for understanding the evolution of the cosmos.
Despite a slight increase, routine depression screening among all US adults remains low, affecting around 8% of American adults. The study's findings also highlight the importance of access to quality psychiatric diagnosis and treatment.
A Rice University neurobiologist and cancer researcher has created a new type of zebrafish that produces fluorescent tags in migratory embryonic nerve precursor cells. The goal is to find the origins of neuroblastoma, which could potentially lead to treatments for cancers where SOX proteins play a role.
The world's insectivorous birds consume a significant amount of energy annually, estimated to be comparable to that of the city of New York. Forest birds play a crucial role in suppressing pest insects, with their annual food intake being around three-quarters of the global prey biomass gathered by insectivorous birds.
Researchers used a peptide nucleic acid-based gene editing technique to successfully cure a genetic condition in mice. The treatment corrected 6% of mutations and caused dramatic improvements in symptoms, suggesting a promising new approach for treating genetic disorders during early stages of development.
A new study found that younger patients (under 50) diagnosed with rectal cancer do not experience a survival benefit from chemotherapy, radiation, and surgery. The findings suggest early onset disease may differ in terms of biology and response to therapy.
A team from Aalto University creates a miniature 'heat valve' in a quantum system, enabling the controlled exchange of energy with external surroundings. This breakthrough aims to improve the efficiency of quantum heat engines and refrigerators.
UCSF researchers identified key genetic changes that transform benign moles into malignant melanoma, including mutations in DNA regulatory genes. They used CRISPR to recreate the steps of melanoma evolution in lab cells, revealing new biomarkers and potential targeted therapies.
A recent study has unveiled the intricate molecular mechanisms behind plant immunity, allowing researchers to unravel bespoke defence solutions against different variants of the rice blast pathogen. The findings have significant implications for engineering disease resistance against a range of crop pathogens.
Researchers found that injecting senescent cells into young mice results in physical dysfunction. Treating the mice with a combination of dasatinib and quercetin cleared senescent cells from tissues and restored function.
A team led by Lehigh University's Brandon Krick is using a Molybdenum Disulphide (MoS2) coating to reduce friction in space, addressing the challenges of high-temperature and corrosive environments. The research aims to improve satellite performance and reduce energy loss.
Research reveals that young adults are more likely to start smoking and using e-cigarettes than adolescents, challenging traditional social norms. This trend has significant health implications, as young adults are less monitored and more independent, making them prone to carrying on smoking.
A new study reveals that many drivers do not perceive texting and driving as dangerous, despite being six times more likely to be involved in a car crash. The study found that factors such as fear of missing out and separation anxiety contribute to this behavior.
A research team from Woods Hole Oceanographic Institution found the fingerprint of a massive flood of fresh water in the western Arctic, which is believed to have caused an ancient cold snap around 13,000 years ago. The cause of this event, known as the Younger Dryas, has remained a mystery for decades.
A WSU study using metabolomics found that shift work schedules alter 24-hour rhythms in digestive organs, disrupting metabolism and increasing the risk of obesity and diabetes. The study suggests that separate biological clocks in the liver, gut, and pancreas play a key role in this disruption.
A study published in Science Translational Medicine found that acetazolamide increases sensitivity to treatment and enhances survival in mice with glioblastoma. The drug, which is also used to treat altitude sickness, was able to restore the effectiveness of chemotherapy by blocking a protein called BCL-3.
Researchers have identified how a new treatment in mice can regenerate the heart after a heart attack by promoting growth of lymphatic vessels and clearing immune cells. This approach showed significant reduction in damaged heart muscle and improved recovery of pumping function.
Researchers at the University of Zurich discovered that black carbon can age for millennia on land and in rivers before being exported to the ocean, forming a major long-term sink for atmospheric carbon dioxide. This finding adds a significant piece to the puzzle of understanding the global carbon cycle.
NASA's Aqua satellite detected two areas of strong thunderstorms with cloud top temperatures as cold as minus 70 degrees Fahrenheit, capable of generating heavy rainfall. The remnants of Tropical Storm Beryl are expected to pass over the Virgin Islands and Puerto Rico today, producing locally heavy rainfall and strong gusty winds.
A study found that stickleback fish respond similarly to predation risk regardless of parental or personal experience, with similar molecular and developmental responses. This challenges traditional models assuming additive effects from different sources.
A recent study published in Annals of Internal Medicine has found that cross-sex hormone therapy may increase the risk for certain vascular events among transgender women. The researchers compared the incidence rates of acute cardiovascular events in a large cohort of transgender persons with those observed in age-, race-, site-, and m...
Researchers develop new microscopy technique to track microstructural changes in real-time under high heat and stress. Alloy 709 shows promising results as a strong and resistant material for elevated temperature applications like next-generation nuclear power plants.
Researchers from UAB successfully used gene therapy to treat type 2 diabetes and obesity in mice by inducing the production of FGF21, a hormone that maintains correct energy metabolism. The treatment led to weight loss and improved insulin sensitivity, reducing the risk of related comorbidities.
A new PET imaging method evaluates the extent of rheumatoid arthritis inflammation by targeting translocator protein (TSPO) expression in joint lining tissue. The study demonstrates that TSPO PET can image not only synovial macrophages but also activated synovial fibroblasts, a critical process in RA pathogenesis.