A study on 563 women who froze their eggs between 2009 and 2017 found that only 12.8% returned to the clinic for reproduction treatment, with an overall success rate of 32.6%. The majority of returning social freezers had found a suitable partner to pursue motherhood.
Researchers at GFZ German Research Centre for Geosciences have developed a new method using fiber-optic cables to detect earthquakes and other ground movements. The technique reveals structural features in the underground with unprecedented resolution, outperforming existing seismological networks worldwide.
Researchers found that fish adjust their escape behavior and keep a safe distance outside the shooting range when a speargun is present. The level of timidity varies depending on the size of the fish, type of diver, and location within protected areas.
Researchers at Columbia University Irving Medical Center found a potential link between microRNAs and sepsis, identifying two molecules that silence inflammatory gene expression. These biomarkers could help diagnose patients at risk of organ failure and death, allowing for faster treatment and potentially saving lives.
A new study by Harvard University researchers suggests that natural selection can favor different personality types in lizards, affecting their behavior and survival. In the experiment, bold lizards were found to survive longer when predators were present, but their mortality increased when predators were absent.
Researchers discovered that men with higher levels of testosterone have a stronger preference for luxury brands, such as Calvin Klein jeans over Levi's. This is because testosterone promotes behaviors associated with status-seeking and status-protecting, similar to animal behaviors like aggression.
Researchers have identified O-linked N-acetylglucosamine transferase (OGT) as a key molecule responsible for the sex-specific patterns of gene expression. High levels of H3K27me3 in the female placenta produce resilience to stress, which may explain why females are less susceptible to neurodevelopmental disorders than males.
Primary HPV testing detects precancerous lesions earlier and more accurately than Pap smears, according to a large randomized clinical trial of nearly 19,000 women. Women who were HPV negative were also less likely to have cervical pre-cancer after four years.
A new computational strategy using Bayesian analysis and CRISPR/Cas9 screening technology has identified 29 genetic changes contributing to rhabdomyosarcoma, a common childhood cancer. The study suggests potential treatments for the disease and provides a general approach for identifying oncogenic drivers in other cancers.
Since the world's first test-tube baby was born in 1978, over 8 million babies have been conceived through IVF, with a record 157,449 babies born in Europe in 2015. European pregnancy rates for IVF and ICSI have stabilized at around 36%, while egg donation treatments have seen significant rises, with pregnancy rates now at about 50%.
The study using data from NASA's NuSTAR space telescope reveals that Eta Carinae accelerates particles to high energies, some of which may reach Earth as cosmic rays. The team's analysis suggests that the accelerated electrons and other particles are ejected in violent shock waves along the boundary of the colliding stellar winds.
A new study at MIT's Picower Institute found that the posterior parietal cortex plays a crucial role in converting vision into action. The research team identified specific neurons in this region that respond to visual patterns and motor actions, suggesting a key link between seeing and acting.
Researchers equip a US bridge with sensors that can detect cracks and alert maintenance engineers, increasing supervision of critical areas and extending structure lifetimes. The system uses Comparative Vacuum Monitoring sensors that can detect tiny cracks smaller than the thickness of a dime.
Research study found that consciousness is not fully lost during general anesthesia, with brain processing words and sounds even when subjects do not recall them. The study used EEG and PET to monitor changes caused by anaesthetics.
By modeling the breakup of an oscillating stream of liquid, researchers have gleaned a better understanding of how sprays form. The study found that an oscillating stream breaks into a wider spray of finer droplets than a straight jet, improving fuel-air mixing efficiency.
A study suggests that nature-based citizen science can reverse the 'extinction of experience' by fostering cognitive and emotional connections to nature. Citizen science programs increase participants' knowledge, skills, interest in and curiosity about nature, leading to positive behavioral changes.
A new paper by Daniel J. Soeder and Douglas B. Kent summarizes the environmental impacts of shale development, providing a balanced understanding of fracking's merits and demerits. The study addresses various potential impacts of fracking, offering insights for non-geoscientists and experts alike.
A Department of Justice investigation into implantable cardioverter-defibrillator (ICD) placement in Medicare patients resulted in decreased use of the devices, especially at hospitals that reached settlements. The study found a significant decline in ICDs placed outside established criteria for reimbursement.
People exposed to paint, varnish, and solvents are 50% more likely to develop multiple sclerosis. Those with the genetic risk factors and solvent exposure have nearly seven times the risk of developing MS compared to those without solvent exposure or genetic risk factors.
Researchers at Florida State University develop novel, modular scheme for producing large quantities of 5-8-5 ring structure, opening door to new medicinal compounds. The simplified methodology could aid scientists in understanding potential medicinal properties of synthetic products.
Researchers found that elderly people who feel younger than their age show fewer signs of brain aging and have increased gray matter volume in key brain regions. This suggests that caring for brain health may be important for those who feel older than their age.
Researchers found greater than expected deforestation in Southeast Asia's highlands, resulting in a 29.3 million-hectare loss of forest between 2000 and 2014. This represents a 57% increase over current estimations, primarily due to agricultural expansion.
A new study reveals that Chile's sugar tax led to a significant decrease in the purchase volume of sugary soft drinks, particularly among high socioeconomic groups. However, the reduction was statistically insignificant for low-income groups, suggesting that further evaluations are needed to address socioeconomic inequalities.
Men treated with ICSI for infertility have a significantly higher risk of developing early-onset prostate cancer, which is considered more aggressive. The study found that this risk is associated with male sub-fertility, not the ICSI procedure itself.
A study published in Nature Communications found that testosterone increases men's preference for luxury products associated with high social status, rather than power or quality. The research team tested 243 male participants and found a causal link between testosterone levels and increased liking for status-enhancing goods.
A research team has used an integrated structural biological approach to elucidate the maturation of a cancer-causing microRNA in gene regulation. Understanding this process may help develop new therapies for cancer treatment.
Nonalcoholic fatty liver disease (NAFLD) has a significant impact on the US healthcare system, with estimated annual costs of $32 billion. The prevalence of NAFLD mirrors the rising trend of obesity in the United States, affecting roughly 100 million Americans.
A recent study found that increased fetal exposure to folic acid due to grain fortification is associated with altered postnatal brain development and psychiatric risk in youth. Cortical thickness on MRI scans revealed significant changes, highlighting the need for further research into micronutrient effects on brain development.
Hurricane Fabio's cloud top temperatures reached as low as minus 63 degrees Fahrenheit, indicating strong storm capabilities. The storm is expected to strengthen into a major hurricane later in the forecast period.
A recent study by University of Texas at Arlington researcher Shima Hamidi finds a correlation between urban sprawl and decreased life expectancy in the US. The study suggests that changes in urban planning and building practices can help improve quality-of-life issues, including life expectancy and economic mobility.
A new quantitative suspension array assay (qSAT) has been developed to measure antibodies against multiple Plasmodium falciparum proteins, simplifying sero-epidemiological studies and vaccine development. The assay is highly sensitive and specific, allowing for detailed analysis of natural and vaccine-induced antibody responses.
Researchers have identified oocyte-specific factors that can drive somatic cell reprogramming by modulating the epigenetic landscape. These factors include histones and their chaperones, histone deacetylases and acetyltransferases, and transcription factors.
Researchers discovered a self-sealing mechanism in the seed pods of Banksia plants, where special waxes melt at 45-55°C to seal small cracks. This adaptation protects seeds from environmental challenges, such as moisture and pathogens, and may have potential applications for dimensionally stable wood.
A large population study from Denmark found no causal association between assisted reproduction treatment and increased risk of ovarian cancer. Female infertility, rather than ovarian stimulation, was associated with an increased risk of ovarian cancer.
A new microfluidics technique has been developed to construct microchannels with efficient gas exchange, potentially delivering nearly a third of the oxygen needed by preterm newborns. The design uses both sides of the membrane for gas exchange and is more effective than previous single-sided counterparts.
Researchers at the University of Pittsburgh developed a new approach to model complex chemical reactions, enabling better understanding of fundamental reactions and their impact on chemical engineering. PhD student Yasemin Basdogan created an artistic depiction of the research for the journal cover.
Researchers found that anticipating stress can lower working memory later in the day, regardless of actual stressful events. This effect was particularly pronounced for older adults, who already experience cognitive decline.
Typhoon Prapiroon's ragged eye became cloud-filled as it moved into the Sea of Japan, affecting the Korean Peninsula and southern Japan. Maximum sustained winds were near 75 mph, with the typhoon weakening due to increasing wind shear and cooler sea surface temperatures.
NASA's Aqua satellite detects Tropical Depression 10W, forecast to intensify into a typhoon. The system is expected to pass over the Marianas late Wednesday night or early Thursday, bringing tropical storm conditions and damaging winds to Guam.
Researchers at UC Davis will investigate human brain's attention systems with higher resolution than ever attempted, aiming to understand and treat attention disorders. They plan to use combined fMRI and EEG methods to measure brain activity in volunteers.
A new study warns that failure to meet the 2°C warming limit will lead to sea level rise and dire global economic consequences. The researchers found that upper-middle income countries like China will see the largest increase in flood costs, while high-income countries will suffer the least.
Multi-wall carbon nanotubes (MWCNT) and polyethylene glycol (PEG) enhance wellbore stability by plugging nano-sized pores in shale formations. This study investigates the effects of MWCNT & PEG on water base mud performance, revealing improved rheological properties and thermal stability.
Researchers found that individuals with more mature personalities view solitude positively, using it for creative activities. In contrast, those with less developed egos tend to avoid solitude and feel lonely.
The study found a 16.1% decline in ICD placements not meeting Medicare coverage criteria at hospitals that settled with the DOJ, while non-Medicare patients also showed declines. Hospital-level variation remained, with top performers having less than 3.8% of ICDs not meeting criteria
Researchers found over 70% of implants colonized by bacteria, fungi, or both, without causing infections. The discovery opens up a new field of understanding the interplay between the body and microbiomes.
Researchers found that increased in utero folic acid exposure was associated with changes in later brain development, predicting a reduced risk for symptoms of psychosis. These findings suggest that prenatal folic acid fortification may be an important intervention in preventing severe mental illnesses like schizophrenia.
Researchers developed a rapid method for creating highly detailed physical models directly from volumetric data stacks, overcoming current limitations in 3D data processing workflows. The new approach enables accurate anatomical details to be replicated in 3D-printed models, improving diagnostics and presurgical planning.
Research predicts a disease burden of 125.8 million DALYs globally due to climate change-induced crop nutrient deficiencies, primarily affecting South-East Asian and sub-Saharan African countries.
This study evaluated perioral soft tissue changes after orthognathic surgery using 3D CT scans. Significant post-operative changes were observed in nasolabial and mentolabial angles, while lip width remained unchanged.
A new study forecasts up to 1,000 additional deaths annually in the Eastern US due to elevated air pollution from increased air conditioning use. The study suggests transitioning to clean energy sources like wind and solar power to mitigate these effects.
The American Orthopaedic Society for Sports Medicine (AOSSM) presents annual research awards and grants to support innovative research initiatives. This year, more than $300,000 was awarded to support projects in osteoarthritis, sports medicine research, and education.
Researchers found the sandy soils in Chaco Canyon were suitable for agriculture, suggesting the ancestral Puebloans were self-sufficient. The most significant challenge was irrigation, where they demonstrated adroit farming skills and land management.
Researchers at Tohoku University developed a new method to synthesize multi-substituted anilines, enabling further developments in medical and materials science. The catalyst-based domino rearrangement reaction offers improved efficiency and selectivity over conventional methods.
A review highlights the importance of early detection, community-based supports, and caregiver education in caring for seniors with dementia. These interventions have been shown to delay admission to long-term care facilities and reduce caregiver stress.
Research reveals that good bacteria interact with epithelial cells and immune system cells to balance immune responses and protect the gut from inflammation. Manipulating the microbiota may offer therapeutic benefits for conditions like inflammatory bowel disease.
Researchers from the University of Miami Miller School of Medicine used an HPV vaccine as an off-label treatment for a patient with advanced squamous cell carcinoma. The patient's tumors completely resolved after direct intratumoral injections, providing promising results in this innovative approach to skin cancer treatment.
The University of Hawai'i Cancer Center has been awarded a $6 million Cancer Center Support Grant to fund research at the Center. The renewal of its National Cancer Institute (NCI) designation recognizes the Center's unique contributions to cancer research and care in Hawaii, particularly for diverse ethnic populations.
A Brazilian research project has identified six genomic regions linked to weight gain in Nelore cattle, a breed adapted to tropical climates. The study, led by Diercles Cardoso, used DNA analysis to pinpoint genes associated with growth and weight gain, offering potential for improvement of the breed's food efficiency.
Researchers at University of Bath and Cardiff University have developed a novel switch to control genome editing, enabling reliable protein expression on demand. The switch uses a cheap, non-toxic amino acid as the control mechanism, addressing concerns over antibiotic resistance and 'leakiness'.
Researchers discovered a neural circuit in parrots that may underlie their intelligence, similar to the pontine nuclei found in primates. The medial spiriform nucleus, located in birds, is comparable in function to the pontine nuclei and plays a key role in higher-order processing and sophisticated behaviors.