The NPS Data Hub allows experts to collaborate and share data on new drug variants, enabling faster identification of emerging threats. By facilitating real-time discussion and collaboration, the Data Hub aims to shorten the time lag between discovery of a new drug and its distribution in law enforcement databases.
Boston University researchers identified risks associated with various cultural practices, including acupuncture, cupping, and moxibustion. Dermatologists need to be aware of these potential complications to provide effective care across diverse cultures.
A review of 16 studies reveals a strong association between fast food intake and an increased risk of asthma, wheeze, and other allergic diseases. Hamburger consumption was found to be most prominently associated with these conditions in a dose-dependent manner, regardless of income level.
Researchers at TGen and Circuit Therapeutics have developed new methods to examine medium spiny neurons in the striatum, a structure crucial for movement, decision-making, and action initiation. They identified Chrm4 as a potential therapeutic drug target, shedding light on how MSN cells contribute to neurodegenerative diseases.
Changes in land use significantly impact CO2 storage in vegetation and atmospheric concentration. Deforestation can lead to reduced capacity for plants and soil to absorb CO2.
Tropical Depression Two formed in the Central Atlantic Ocean on July 5, 2018, with maximum sustained winds of near 35 mph. The system is forecast to potentially strengthen into a tropical storm and then degenerate into an open trough east of the Lesser Antilles over the weekend.
A new study examines the impact of salmon poisoning disease on grizzly bears in the North Cascades and central Idaho. The research suggests that using bears with no history of salmon consumption may not be effective due to their sensitivity to the disease, complicating recovery plans.
Researchers at Cardiff University have developed a potential new treatment for schistosomiasis and fascioliasis, two devastating tropical diseases. The goji berry-derived drug compound shows promise in combating the parasites that cause these conditions.
A team of physicists has captured the behavior of a five-atom molecule's atomic nuclei and chemical bonds in response to a laser, revealing the clearest glimpse yet of a photochemical reaction. The study marks a significant advancement in understanding these light-fueled molecular transformations.
The number of scientific publications in the Web of Science has skyrocketed, increasing by 72.81% from 31,690 to 54,764 documents between 2007 and 2016. This growth is attributed to an increase in international collaborations.
Current opioid epidemic responses neglect to account for gender-specific factors, including pain sensitivity and treatment outcomes. Women are disproportionately affected by opioid addiction, with increased risk of overdose deaths and limited access to effective treatment options.
Researchers from Russia and India have developed a narrow-band UV photodetector based on indium oxide nanocrystals embedded in aluminum oxide. The device shows record values of responsivity and external quantum efficiency, making it suitable for applications such as fluorescence detection and UV phototherapy.
A genetic study uncovers that pre-contact American dogs originated from Siberian ancestors, not native wolves, and were introduced to the region through Beringia. Meanwhile, ancient goat domestication in the Near East involved multiple wild sources and selective breeding for traits like color.
A study analyzed 4,701 comments on physician review sites, finding that negative ratings for office staff, billing, and wait times are more common than for surgeon competence or outcomes. Surgeon-independent factors, such as office environment and billing, have a significant impact on overall scores.
Scientists from the University of Bristol have discovered that spiders can become airborne in the absence of wind when subjected to electric fields, defying current theories on aerodynamic drag. The researchers believe that electric fields trigger ballooning and provide lift, revolutionizing our understanding of spider dispersal.
Researchers at Lehigh University have designed a small-molecule compound to decorate the surface of Gram-negative bacteria and trigger an immunological response. The compound targets pathogenic bacteria in two distinct ways, generating a promising lead for immunotherapeutic agents against deadly, antibiotic-resistant bacteria.
Scientists successfully regenerate skeletal muscle cells in mice with muscular dystrophy by using cells from animal teratomas. The study showed improved potential with 80% regeneration compared to the current 5-10%.
Researchers at Kyushu University have demonstrated a way to split energy in OLEDs, surpassing the 100% limit for exciton production. This new technology uses singlet fission to convert electrical charges into light with high-intensity near-infrared emission.
Researchers developed a deep-learning model to predict biological age of muscles and estimate the importance of genetic and epigenetic factors driving muscle aging. The study identified tissue-specific biomarkers of aging, which can be used to track the effectiveness of interventions.
A research team at TUM has reconstructed the protein complex responsible for transport within cilia, crucial for cellular movement and organ development. The study reveals a minimal combination of four proteins that start the engine of intraflagellar transport.
Researchers synthesized tetrapeptide PAGY and its analogues using solid phase peptide synthesis, screening their antioxidant properties. The results showed that PSGY exhibited the highest DPPH inhibition activity, while modifications in amino acid sequences increased or decreased antioxidant activity.
The grant aims to prepare MSU nursing students for community-based primary care settings and provide professional development opportunities for registered nurses. Key findings include the project's focus on recruitment of American Indian students into the MSU College of Nursing and a new community-based primary care nursing track.
Researchers discovered that Anaplasma bacteria alter the microbiota of mouse and shrew spleens, changing bacterial compositions. The study highlights wild animals as potential reservoirs for tick-borne diseases with public health importance.
A major study found that one in three pregnant women in Norway has a vitamin D deficiency at the end of their pregnancy. Low levels can affect bone health and increase the risk of asthma in children. The study suggests that small measures, such as taking supplements and eating fish, can have positive effects on vitamin D levels.
The University of California, Irvine has received a $5 million National Science Foundation grant to support nearly 200 community college transfer students pursuing engineering degrees in advanced manufacturing. Under the program, each student will receive up to $10,000 annually over five years.
A study by NRG Oncology/RTOG 0424 found that MGMT promoter methylation is associated with improved progression-free and overall survival in high-risk, low-grade glioma patients. The analysis suggests that MGMT promoter methylation should be incorporated into future clinical trial designs to risk-stratify LGG patients.
A recent meta-analysis compared the efficacy and safety of antihypertensive drugs during pregnancy. Labetalol, hydralazine, and nifedipine were found to have similar efficacy with negligible differences in their safety profile.
Researchers developed a new assay to measure nucleation, the first step in prion transformation, allowing them to distinguish between proteins with prion behavior and those without. This approach may help understand prions associated with diseases as well as their role in normal biological processes.
A study suggests that abnormal metabolism of three essential amino acids may contribute to the development of type 2 diabetes in women who have a history of gestational diabetes. Women with a history of gestational diabetes had higher levels of branched-chain amino acids in their blood, regardless of their dietary intake.
A study of 149 patients undergoing arthroscopic rotator cuff repair found significant functional improvements and pain relief through the procedure. Males demonstrated better outcomes than females, while pre-operative narcotic use correlated with poorer results.
Scientists discovered that mitochondria and nuclear genomes co-evolved to independently cross-regulate each other. This understanding could lead to greater insights into aging and disease, as well as new treatments based on mitochondrial DNA.
A Texas A&M University-led consortium has been awarded a five-year, $10 million grant to establish the Center for Excellence in Nuclear Training And University-based Research (CENTAUR). The center aims to develop next-generation leaders in low-energy nuclear science. CENTAUR will pursue basic research using accelerators at various inst...
Research suggests that oxygen therapy can improve the function of blood vessels in the brains of individuals with chronic obstructive pulmonary disease (COPD), a common cause of dementia. This study found that delivering additional oxygen increased blood flow and oxygen delivery to the brain, matching its demands during activity.
Researchers found that young female athletes who underwent ACL reconstruction using bone-patellar tendon-bone (BTB) or quadrupled hamstring (HS) autografts had different outcomes. The study revealed higher re-tear rates in younger patients using HS autografts compared to BTB, suggesting that age affects graft repair success.
Researchers have identified a new target for treating certain types of leukemia by exploiting an existing FDA-approved drug, Ibrutinib. This discovery could provide another treatment option for patients and accelerate clinical trials.
Researchers analyzed 5,600 studies, finding improved Risk of Bias (ROB) domain measurements since 2000. The study recommends enhancing researcher training, publishing transparent funding reports, and monitoring for improvement to increase public trust.
Researchers have demonstrated a record-breaking 4000 km fiber-optic transmission link using ultra low-noise phase-sensitive optical amplifiers, improving reach by almost six times conventional optical amplifiers. The technology has significant potential to enhance video streaming, cloud storage and online services.
Research reveals that ancient American dogs disappeared rapidly following the arrival of Europeans, leaving little genetic signature in modern American dogs. A close relative of these dogs lives on as a transmissible cancer, with its genome mirroring that of the original dog.
The RTOG 0618 trial found Stereotactic Body Radiation Therapy (SBRT) to achieve favorable primary tumor control and local control rates in operable early-stage lung cancer patients, with a low rate of toxicity. The results suggest that SBRT may be a viable alternative to surgery for this patient population.
A new software has been developed to automate the identification of dendritic spines in brain cells using machine learning. The software can identify spines with over 90% accuracy and is designed to be fast, scalable, and easy to use.
Typhoon Maria brought heavy rain to Guam, with the National Weather Service issuing a Flash Flood Watch and Small Craft Advisory. The storm is forecast to continue intensifying over the next 24 hours, posing a threat of excessive rainfall and flash flooding.
Researchers used precision genomics to identify new genetic abnormalities associated with short telomeres, which can cause premature aging. The study aimed to find better ways to screen, diagnose, and treat patients with these rare conditions.
The Higgs boson-top quark coupling has been observed at the LHC, confirming theoretical predictions of the Standard Model. The detection was made possible by an increase in the collider's energy, allowing for the distinction between two points as small as 10-18 m apart.
Researchers at the University of Illinois and Texas have optimized boron arsenide crystal growth to create materials with excellent thermal properties. The new material can effectively dissipate heat, outperforming existing heat spreaders three times over.
Researchers detected pesticides in hummingbird cloacal fluid and fecal pellets, as well as in bumble bee pollen and blueberry flowers. The findings suggest pesticide exposure may impact the health and ecosystem services of these pollinators
Research shows bears disperse seeds through their scat, benefiting small mammals like mice and voles. These animals feed on the seeds, sometimes further dispersing them, creating a network of seed-filled hoards.
Researchers at the University of British Columbia have developed a cheap and sustainable way to build solar cells using bacteria that convert light to energy. The cell generated a current stronger than any previously recorded and worked efficiently in dim light, offering a promising solution for regions with frequent overcast skies.
A newly discovered neural circuit in mice regulates feeding behavior, with SST neurons playing a central role. The study reveals that activating these neurons increases eating behavior, while inhibiting them reduces it.
Researchers have found a non-opioid drug that targets immune cells to relieve pain, providing an alternative to addictive opioid drugs. The investigational drug, EMA401, inhibits the angiotensin II type 2 receptor on macrophages, leading to pain signal transmission.
Gonorrhea researchers have identified a novel protein that powers the virulence of the bacteria causing gonorrhea, opening the possibility of a new target for antibiotics. The discovery could lead to the development of a vaccine and improved treatment options for the highly damaging disease.
A new study found that 'skinny fat,' a combination of low muscle mass and high fat mass, may predict cognitive decline in older adults. Sarcopenic obesity was associated with the lowest performance on global cognition tests, followed by sarcopenia alone and then obesity alone.
A study by University of Huddersfield researchers suggests that carbohydrate gels and caffeine-infused chewing gum can help teams perform better in extra time. The five-minute window before extra time begins is crucial, but teams may also need to develop better nutritional strategies.
Extended tamoxifen therapy for 10 years increases the risk of developing endometrial cancer by two-fold compared to standard 5-year treatment. Screening for endometrial cancer may be necessary in patients receiving extended tamoxifen therapy.
Researchers have successfully used viral vectors to deliver genetic material to kidney cells, paving the way for new treatments for chronic kidney disease. The discovery could lead to gene therapies that slow or reverse the growth of cells contributing to CKD.
Researchers found a significant rise in myopia rates among Chinese schoolchildren, with some studies suggesting an annual incidence rate of up to 30%. This could be attributed to increased screen time and sedentary lifestyles, prompting recommendations for outdoor playtime and other interventions.
A new study by UBC researchers reveals that urban greenways can significantly reduce daily car travel distances and resulting carbon emissions. Participants living within 300 meters of Vancouver's Comox-Helmcken Greenway showed an 18% decrease in car travel, while those farther away experienced increased motorized travel.
A new study led by University of Pennsylvania researchers has discovered the underlying factors causing ichthyosis, a skin barrier disorder that leads to thick layers of scales. The team developed a topical therapy using a lotion that restored the skin's natural lipid envelope, improving symptoms in affected dogs.
The Cheetah 3 robot can navigate staircases littered with debris and recover its balance when yanked or shoved, thanks to two new algorithms developed by MIT engineers. The contact detection algorithm helps the robot determine the best time for a leg to switch from swinging in the air to stepping on the ground.
The KAIST research group created photonic capsules that can be injected into any target volume, exhibiting omnidirectional laser emissions. The capsules contain cholesteric liquid crystals (CLCs) with helical nanostructures, which reflect circularly-polarized light and enable wavelength-tunable lasing.
Investigative report finds 40 physician advisors took over $10,000 from drug makers after reviewing drugs, while 26 received more than $100,000 in post-hoc earnings. The FDA's honor system for disclosing financial interests may be ineffective in detecting conflicts of interest.