Two proteins, SmMBD2/3 and SmCBX, play essential roles in the biology of Schistosoma mansoni, particularly in egg production. Disrupting these proteins' activity could lead to new drug targets for controlling schistosomiasis.
Researchers found that smoking significantly delays bone healing and increases risk of nonunion among women aged 30-49. The study analyzed patient records over 20 years and revealed a significant delay in bone healing among smokers, with implications for treatment and prevention strategies.
Male cheetahs employ two space use tactics: floaters roam over vast areas and territory holders mark and defend small territories. Females use home ranges with sizes between those of territory holders and floaters, highlighting the need for huge natural areas to conserve these cats.
Spanish researchers developed a system to track human migration caused by climate change using mobile phone tracks. The model achieved over 60% prediction success rate for displacements in Colombia's La Guajira region during a severe drought, highlighting the importance of economic opportunities and urban areas in migration decisions.
A new study estimates mortality rates for nearly 4,000 Italians over 105 years old, finding a plateau in death rates after age 105. The research suggests that human longevity is increasing over time, with slight declines in mortality rates across groups born within the same year.
Researchers have developed a new catalyst that increases the rate of methanol formation by three times over palladium alone and four times over copper alone. The catalyst combines palladium and copper in a precise atomic ratio, creating an ideal surface structure for efficient CO2-to-methanol conversion.
A new study found that Instagram users portraying hookah use in a positive manner despite its serious health risks. Most posts were promotional and associated with nightlife, community, and hookah identity. The study suggests policymakers should explore approaches to reduce promotional posts and create counter-marketing campaigns.
Research found people selectively identify with ethnicities they view as positive while disregarding others. White respondents were more likely to embrace new racial identities if they felt others would still accept them.
Researchers at Oak Ridge National Laboratory have discovered a new mechanism for heat transfer in solids, supported by Einstein's 1911 theory. This 'heat-hopping' process occurs in thermal insulators and may be present in other crystalline solids.
Scientists at Scripps Research found that several existing FDA-approved anti-cancer drugs bind tightly to RNA, modulating targets and causing some effects. The discovery offers a promising new approach for tackling diseases considered undruggable, including ALS and certain cancers.
NASA's Aqua satellite captured an image of newly formed Tropical Depression 09W in the Northwestern Pacific on June 28. The storm has tracked westward at 8mph and is expected to become a tropical storm on June 29.
A study found that women living in socioeconomically deprived neighborhoods for longer periods had an increased risk of non-optimal weight gain during pregnancy. Non-optimal weight gain is linked to low birth weights and preterm birth.
Researchers found that billing codes were rarely used by hospitals and did not significantly affect diagnosis-related group (DRG) assignment, leading to insignificant financial penalties. The study suggests that CMS policy may have inadvertently led to increased documentation of conditions at admission.
A new lab diagnosis guide from IDSA and ASM aims to help healthcare providers accurately diagnose infectious diseases with rapid molecular testing. The guide provides detailed guidance on test selection, specimen collection, and laboratory management to ensure accurate diagnosis and treatment.
Researchers have discovered ancient Moroccan dental remains that shed light on the history of long-lost African fauna, including embrithopods. The fossilized teeth belong to two new species in the genus Stylolophus and provide evidence for the early evolution of these mammals.
Researchers create flexible terahertz imagers based on semiconducting carbon nanotube materials that can be fine-tuned to maximize detector performance. The findings expand the scope of terahertz applications, enabling wearable technologies and large-area photonic devices.
Research from Florida State University and Emory University found that teachers receiving SCERTS training significantly improved student outcomes for children with autism spectrum disorder. The study showed that trained teachers led to increased student participation, back-and-forth conversations, and better emotional regulation.
A Portsmouth researcher is developing a mathematical model to speed up the delivery of life-saving blood to victims of disasters, reducing blood wastage and loss of life. The model will inform venue and location for temporary blood donation centres, transportation routes, and quantities delivered.
Researchers found that a dietary supplement derived from glucose increases muscle-force production in the Duchenne muscular dystrophy (DMD) mouse model by 50% after ten days. The study suggests that N-acetylglucosamine may preserve muscular strength and is an inexpensive product with potential as a treatment for DMD patients.
Researchers warn of significant changes in regional rainfall patterns over densely populated Eastern China due to global warming. The study, published in Advances in Atmospheric Sciences, reveals that increased CO2 forcing leads to differing responses on interannual and interdecadal timescales.
Tropical Depression Six-E strengthened into Tropical Storm Emilia after being tracked by NASA's GPM satellite, producing heavy rainfall and powerful storms. The storm is moving west-northwest at 14 mph with maximum sustained winds near 40 mph.
Researchers identified exosomes as the main vehicle for spreading toxic proteins that trigger Alzheimer's Disease. Exosomes carrying oligomer amyloid-beta facilitate brain cell death, and their measurement could serve as a diagnostic tool.
To achieve zero emissions, air travel, freight shipping, cement, and steel manufacturing must be decarbonized. New technologies, such as hydrogen fuels and carbon capture, can help overcome these challenges.
A UCI-led review emphasizes the need to redesign heavy-duty infrastructure to eliminate carbon dioxide emissions. Key solutions include the production of renewable materials, capturing and storing CO2, and integrating power and manufacturing facilities.
Researchers identified specific parameters required to manage a conflict-prone system, which can be controlled to create conditions for preventing social conflicts. The model uses diffusion equations to simulate social systems' behavior and identifies characteristic stable modes of functioning.
A new University of Guelph study found people in consensual non-monogamous relationships experience similar levels of satisfaction and well-being to those in monogamous ones. Consensually non-monogamous relationships are more common than thought, with 3-7% of North Americans involved.
A high-fat, high-sugar diet that leads to obesity may contribute to the development of Alzheimer's disease when paired with normal aging. The study found significant differences in inflammation and insulin resistance markers between obese and healthy mice.
A study of 27 patients with late-stage CKD found that interactions with clinicians and the health system can take a large emotional toll. Patients struggle to make sense of their illness, blame themselves, and feel abandoned or isolated.
A new study published in Brain Stimulation reveals that people undergoing voluntary and involuntary electroconvulsive therapy (ECT) have similar outcomes, providing reassurance for those who received involuntary treatment. The study found that both groups showed significant improvement, but individuals receiving involuntary ECT were mo...
A recent study by the University of Seville has shed new light on the mysterious Abrigo de Matacabras cave paintings, dating back to the 4th millennium BC. The analysis suggests that this site was a significant cultural reference point for Neolithic populations in the region.
Scientists at Tufts University visualized the flu virus's dynamic surface protein structure that reaches out to hijack target cells, revealing a 'better mousetrap' mechanism. The discovery sheds new light on viral entry and may help develop more effective vaccines.
A landmark study published in Nature Geoscience reveals the Great Barrier Reef has suffered five death events over 30,000 years due to variations in sea level and associated environmental changes. The reef adapted by migrating up and down the seafloor, demonstrating remarkable resilience.
Researchers at Chalmers University of Technology discovered a speed limit for smart technology gadgets that control light and internet traffic. By manipulating individual particles or allowing speciality materials to remain in motion, they can bypass this limit.
The California Institute for Regenerative Medicine (CIRM) has awarded City of Hope $3.7 million to develop a phase 1 clinical trial for glioblastoma patients that will genetically engineer their stem cells to better tolerate chemotherapy's side effects, allowing them to receive higher doses of the therapy. The trial is expected to star...
A team of biologists has shed light on how lamins maintain the relative positions of DNA segments throughout the nucleus, influencing gene expression. This finding has implications for understanding lamin-associated aging and diseases, including premature aging, neuropathies, heart defects, and organ decay.
A substantial proportion of adult survivors of childhood cancer report a lack of concern about their future health, despite being at elevated risk for serious chronic health conditions and subsequent cancers. The study suggests that this may lead to less engagement in cancer screening and healthier behaviors.
Scientists found microRNA changes detectable in mice before symptoms of Alzheimer's disease appear. The study suggests microRNA-142 may be a key biomarker for the condition.
Researchers have discovered a new type of magnetic particle-like object, chiral bobbers, which offer opportunities to encode digital data directly. Unlike skyrmions, chiral bobbers can flow freely without needing precise distances between successive data bit carriers.
Researchers at the Institute for Basic Science discovered that asymmetric apertures can cause astigmatism in microscopes, leading to degraded image resolution. By correcting for this effect, they improved the technique of line-temporal focusing microscopy, achieving unprecedented resolution in biological structures.
A predictive model analysis of Medicare claims reveals that less than 5% of end-of-life healthcare spending goes to those with a mortality risk above 50%, who are more likely to survive. Adjusting for the amount spent on sick individuals, 30-50% of end-of-life spending can be eliminated without affecting survival rates or quality of life
A study published in Cell found that a specific region of the brain's frontal lobe controls vocal pitch, enabling humans to convey meaning through speech and language. By examining neural activity and using brain sensors, researchers identified increased activity in this region when participants altered their voice pitch.
Researchers at the University of Iowa and National Institute on Deafness and Other Communication Disorders have discovered a novel drug therapy that partially restores hearing in mice with an inherited form of progressive human deafness. The study sheds light on the molecular mechanisms underlying this condition, suggesting a new treat...
A new observational study reveals that apixaban is potentially safer than warfarin in dialysis patients with atrial fibrillation, with a significantly lower risk of major bleeding. The study found that patients on apixaban had a 30% lower risk of major bleeding without a difference in stroke rate.
Researchers have found a new test that significantly improves the identification of bladder tumors likely to recur and progress. The test involves examining STAG2 gene expression in removed tumors, offering additional predictive discrimination.
In a study on chimpanzee communication, researchers found that males combined the 'leaf clip' gesture with pant hoots, making them more salient and acoustically complex. This behavior emerged during an alpha male takeover and may help alleviate stress and competition among males.
A recent international study has identified three regions in the genome with significant genetic differences between men and women for developing glioma. These differences vary by sex and type of tumor, suggesting a potential path to assessing patient risk for brain cancer through genetic tests.
Researchers create nanoaggregates of microtubules by controlling their aggregation in response to light. The aggregation can cause cell death, making it a potential target for diseases caused by protein misfolding.
Researchers have discovered security weaknesses in the LTE mobile telephony standard, which enables attackers to intercept user data and reroute them to malicious websites. The study highlights that even with HTTPS protocol configuration, some information remains accessible to attackers.
The endolymphatic sac acts as a pressure-relief valve for the inner ear, regulating fluid pressure and composition. The discovery may inform the study and treatment of disorders like Meniere's disease.
A new study from the University of Illinois provides information on the effects of rice bran on growth performance and carcass quality of growing-finishing pigs. The results show that including 30% full-fat rice bran in diets improves gain-to-feed ratio without affecting carcass characteristics or meat quality.
Researchers at Penn State developed a self-heating battery that can rapidly charge regardless of outside temperature. The battery's unique design allows for 15-minute charging at temperatures as low as -45 degrees F, reducing range anxiety and increasing driving distances.
A study found that social support from family and friends is a key factor in deciding an individual's suitability for an organ transplant. The research suggests that this criterion may sanction existing prejudices and widen inequalities in the selection process.
The article highlights predatory monetization schemes in video games, such as loot boxes, that can encourage repeated spending and blur the line between gaming and online gambling. These schemes have been linked to Internet gaming disorder and pose significant financial risks to vulnerable players.
The study investigates KAPS surveys' use in Nepal's development, highlighting potential 'epistemic pollution.' It suggests neoliberal values have led to research serving solely instrumental and ritualistic purposes.
Researchers at Johannes Gutenberg University Mainz have developed an electrochemical synthesis method for thebaine, overcoming decades-long challenges in mimicking its natural formation. The new approach uses astute modification of starting materials to achieve high selectivity and efficiency in the reaction.
A new study by UC San Francisco scientists reveals the brain area responsible for controlling vocal pitch in humans. The dorsal laryngeal motor cortex is found to govern the 'music' of speech, enabling flexible control over pitch fluctuations during speech.
Researchers found that humans can estimate physical formidability from nonverbal vocal cues, including aggressive roars and speech. Listeners accurately judged vocalizers' strength in 88% of trials, with men perceiving themselves as stronger than women in similar situations.
A study of nearly 4,000 extremely old Italians found that mortality rates plateau after 105 years old, with people between 105-109 having a 50/50 chance of dying within the year and an expected further life span of 1.5 years. The findings challenge previous research on a final cut-off point for human lifespan.
A team of scientists has developed a low-cost and portable method for detecting nerve agents using a combination of Lego bricks, a smartphone camera, and a UV lamp. The new device can distinguish between different classes of nerve agents and provide quick results, which is crucial in preventing mass harm.
A new study published in Journal of the American Heart Association found that young adults who frequently binge drink are more likely to have risk factors for cardiovascular disease. The research revealed that young men who reported repeated binge drinking had higher systolic blood pressure and cholesterol levels than non-binge drinker...