Researchers at Washington University in St. Louis found an enzyme that breaks down plasmalogens, a phospholipid abundant in the heart and brain, shedding light on their role in Alzheimer's disease and other conditions.
A global study found that Leguminosae trees are twice as common in dry compared with wet secondary forests during the first three decades of natural forest regeneration. These trees have high drought tolerance and can fix nitrogen from the atmosphere, making them essential for tropical forest regrowth in dry regions.
IDMC recommends continuing Zepsyre® (lurbinectedin, PM1183) Phase III trial in small-cell lung cancer patients. The pivotal trial assesses the efficacy of PM1183 in combination with doxorubicin compared to standard treatments.
The University of Surrey has created a mathematical model that more accurately details how hepatitis C (HCV) infection develops and behaves. This new model could lead to improved treatment for the infection affecting 215,000 people in the UK.
Mesoscience offers broad potential beyond chemical engineering, tackling complex systems in the real world with unprecedented approach. The concept is attracting increasing attention from top scientists worldwide.
The Van Allen Probes mission has identified local acceleration as the main cause of highly energized ions and electrons in the radiation belts, contrary to previous theories that suggested radial diffusion was the primary driver. This discovery is crucial for improving space weather forecasting models.
Researchers have successfully tested an existing prescription drug, fingolimod, on lab cultures infected with mucolipidosis IV (MLIV), a rare genetic disease that causes severe neurological damage. The study suggests that fingolimod may help regulate abnormal astrocyte behavior and improve brain function in MLIV patients.
Researchers have discovered a previously overlooked connection between neurons in two distinct areas of the mammalian brain that control the sense of touch. In mice, layer 4 neurons in the S2 region extended their axons beyond their local area to reach neurons in the S1 region, suggesting a link between movement and sensation.
A Northwestern University research team has discovered a new battery material with a record-high charge capacity, enabling smartphones and electric vehicles to last more than twice as long between charges. By adding oxygen to the traditional cathode compound, the battery achieves higher capacity and stability.
Scientists employed passive acoustic vibrations to characterize the vibrational modes of granular materials, revealing a new method to predict failure. The technique measures active vibrational modes' frequencies, providing an acoustic snapshot of the material's overall health.
Sheereen Majd aims to improve nanoparticle drug delivery by targeting diseased cells and minimizing off-targeting. Her research combines existing technologies to create a precise and stable carrier system, promising efficient delivery of bioactive molecules to specific sites in the body.
Researchers have developed a new tool that can work in both non-reproductive cells and egg-producing cells using the Gal4/UAS two-component activation system. The UASz vector has been shown to express about 4 times higher than UASp in the egg-producing system, overcoming previous limitations.
Researchers at the Johns Hopkins Center for Health Security have developed a forward-looking framework for identifying naturally occurring microorganisms that pose a global catastrophic biological risk (GCBR). The report outlines common characteristics of a potential GCBR-level pandemic pathogen, including respiratory mode of transmiss...
Researchers have developed a novel RNA-modifying tool called RIBOTAC, which uses a small-molecule-based approach to selectively delete toxic gene products and control the body's defense mechanisms. This technology has potential applications for treating genetic diseases such as cancer and incurable human genetic disorders.
Researchers at Binghamton University are developing a micro-device using bio-photovoltaic technology to create self-sustaining wireless sensor networks. The project aims to harness energy from biological photosynthesis to improve wireless sensing and communication, with potential applications in various industries.
Researchers at Oxford University have created a lab-based approach to develop defensive relationships between hosts and bacteria, which can work together to prevent infection. The study found that these relationships can evolve quickly in a matter of weeks, providing a new potential solution to the growing superbug crisis.
Scientists have successfully separated two forms of water, ortho- and para-water, which exhibit different chemical reactivities due to their nuclear spin orientations. These findings were reported in Nature Communications and confirmed by computer simulations.
Michigan Tech researchers explore lithium's mechanical properties to improve battery storage capacity and safety. Their findings highlight the importance of lithium's orientation-dependent elastic properties in controlling battery performance.
Researchers at Lobachevsky University discovered hormesis and paradoxical effects in plants under formaldehyde exposure, affecting growth and biochemical indicators. This study contributes to improving environmental assessment methods using plant parameters.
The Wayne State University College of Nursing is expanding its BSN training program with a $2.6 million HRSA grant to address the growing need for nurses working on community-based primary care and public health teams. Students will participate in immersive clinical experiences alongside RNs in Detroit's community settings.
Researchers at Columbia University have developed a new non-invasive approach to permanently correct vision. The technique uses a low-powered ultrafast laser to alter biochemical and biomechanical properties of collagenous tissue, resulting in changes in corneal curvature and refractive power.
The collaboration aims to use clinical insights to fine-tune early device testing, focusing on preclinical support, proof of concept studies, de-risking medical device translation, and rapid prototyping. Tufts CTSI and MIT will provide resources and expertise to research teams to efficiently turn device concepts into testable prototypes.
Plastic surgeons are crucial in managing young women at high genetic risk of breast cancer due to BRCA gene mutations. These women have a low lifetime risk of breast cancer, only 1.5-3.4% by age 30, and may benefit from mastectomy, but the decision is complex and requires careful consideration.
A study of over 2,800 postmenopausal women found that a higher proportion of male to female sex hormones was associated with a significant increase in cardiovascular disease risk. The researchers suggest that having a more male-like hormone profile may affect heart disease risk independent of other risk factors.
Researchers at NIST developed a novel power meter called 'Smart Mirror' that measures laser power in real-time using radiation pressure. The device is compact, sensitive, and fast, enabling continuous measurement during welding and calibration processes.
Researchers developed a new method to convert complex medical images into physical models with unprecedented detail. This technique uses dithered bitmaps to simplify grayscale images, allowing for faster and more accurate printing.
Researchers at Salk Institute discovered that cells from older individuals had impaired mitochondria, leading to reduced energy production. This finding could reveal more about the link between mitochondrial dysfunction and age-related brain diseases.
Researchers created personalized brain models using The Virtual Brain platform, accurately predicting the effects of tumors on brain connectivity. This breakthrough opens up new possibilities for integrating neuroimaging data with virtual brain modeling to enhance surgical planning.
A new study aims to identify the causes of the gender pay gap in medicine through dataset interrogation and qualitative evidence, with the goal of offering actionable recommendations. The project, led by Professor Carol Woodhams, will inform future decision-making for the Doctors' Pay Review Body.
A Penn-led trial has shown that AZEDRA can significantly reduce cardiovascular side effects and stop tumor growth in patients with pheochromocytoma and paraganglioma. The drug is effective in controlling tumor size while also alleviating debilitating symptoms caused by excess hormone production.
The Specify team has adopted a biological museum-membership organization to migrate from grant-supported to community-supported funding. The new model allows institutions of all sizes to contribute to the operating budget, while maintaining open-source software licensing and free access for users.
Researchers developed an imaging technique that reveals tiny brain motions induced by blood pulsation and CSF flow, enabling better visualization of brain motion. This method promises a long-awaited diagnostic tool for obstructive brain disorders, such as Chiari malformation I.
A new study published in Anesthesiology found no significant differences in death rates, hospital length of stay or costs between anesthesia care teams led by a physician and assisted by a nurse anesthetist or an anesthesiologist assistant. Physician supervision lessens any training differences between the two.
A MSU neuroscientist published research that reveals how the brain maintains attentional focus during eye movements, which could lead to new treatments or therapies for some brain disorders. The study's findings may also contribute to the development of screening technologies and targeted behavioral therapies for conditions like autism.
Researchers at DOE's Princeton Plasma Physics Laboratory discovered a way to more accurately measure the electrical properties of plasma. They found that a positive charge can sometimes surround probes, contradicting long-held assumptions about the plasma-wall sheath.
Researchers at UTSA created an authorization framework for connected cars to prevent cyber attacks and unauthorized access to sensors and data. The framework provides a conceptual overview of various access control decision and enforcement points needed for dynamic interaction in smart car ecosystems.
A new study provides a unified model for understanding tidal disruption events, which occur when a star is torn apart by a supermassive black hole's gravity. The model reveals that viewing angle accounts for differences in observed properties of these events, offering a coherent framework for researchers to analyze.
A team of researchers from Ruhr-University Bochum has discovered an olfactory receptor in human bladder tissue that may prove useful for bladder cancer therapy and diagnosis. The receptor, OR10H1, responds to sandalwood scents and inhibits tumour growth when activated.
Three-dimensional printed models provide a useful visual reference for plastic surgeons performing rhinoplasty, helping to achieve the desired clinical result. The models also improve communication with patients before surgery, making it easier to understand the surgical possibilities and limitations.
Researchers found a crucial structural element in spider silk proteins that forms strong beta-sheets, enabling quick weaving. The study used advanced spectroscopy methods to analyze the soluble protein before it formed into solid sheets.
The University of Texas at Arlington has received a Robert Noyce Teacher Scholarship Program grant from the National Science Foundation to promote STEM teacher recruitment, preparation, and induction. The grant adds computer science and engineering teachers to the pool, benefiting students pursuing secondary certification.
A case study and literature review concludes that breastfeeding should continue normally in mothers and babies with red diaper syndrome caused by Serratia marcescens. Treatment of the bacteria is not recommended for healthy infants, and clinical judgement should guide physicians' decisions.
Researchers found that honey bees shift their nutrient intake according to the season, increasing calcium consumption in the fall and seeking high-potassium sources. This adaptation helps prepare the bees for colder months when they need these minerals to generate warmth.
A University of Alberta study found that nearly six per cent of patients have a heart attack without any blockage in the arteries, with five per cent experiencing another heart attack or death within one year. Patients with MINOCA are twice as likely to be female and require more aggressive preventive treatment.
Researchers developed a natural, non-toxic hair dye from blackcurrant skins that is as durable as conventional dyes and retains color through multiple washings. The dye's anthocyanin-based formula shows promise in addressing environmental concerns and potential health risks associated with traditional hair coloring.
A new study by Cedars-Sinai investigators found that online physician satisfaction scores tend to be skewed and can mislead patients. The study examined data from Healthgrades and found that ratings consistently skewed positively and had different distributions across specialties.
A UTA engineer has developed computer tests and games that track individual brain functioning, providing a more objective measure of brain performance. The technology aims to help people make smarter decisions about their brain health and impacts daily life.
The American Cancer Society report highlights a decline in ovarian cancer incidence and mortality rates in the US, with significant reductions seen among white populations. The strongest risk factor for ovarian cancer is a family history of breast or ovarian cancer, with BRCA1 and BRCA2 mutations accounting for nearly 40% of cases.
A new study from Boston Medical Center and Boston University found that stronger alcohol policies significantly reduce the likelihood of alcohol-related car crashes, resulting in lower death rates. The research indicates that comprehensive policy approaches are needed nationwide to address this critical public health concern.
New research by Rice University geophysicists reveals that the asthenosphere's convective cycling and pressure-driven flow can move faster than the tectonic plates on top of it. This challenges a long-held theory that the lithosphere moves independently of the asthenosphere.
A study by Portland State University finds that removing dams could save up to $64 billion compared to repairing them. The research suggests that better data and analysis are needed to inform dam management decisions.
A new study links divorce to increased risk of smoking and lower physical activity levels, which can lead to early mortality. Divorced individuals report lower life satisfaction, predicting poorer health outcomes.
A new study by the American Heart Association found that high protein diets may be associated with a small increased risk of heart failure in middle-aged men. The study followed 2,441 men over an average of 22 years and found that those who consumed more protein had a slightly higher risk of developing heart failure.
Researchers at Monash University have developed a hand-made super-microscope capable of seeing the building blocks of bacterial cell walls. This discovery has shed light on how bacteria evade the immune system, providing key knowledge to disarm superbug resistance.
A Penn Medicine study reveals that early-life seizures can lead to premature activation of synapses tied to learning and language skills in children with autism. The researchers found that an antiepileptic drug may keep these synapses 'silent' longer, allowing the brain to develop normally.
Alberto has weakened to a subtropical depression with strongest storms circling its low-level center, producing heavy rainfall and flash flooding concerns.
Research finds people experience more regret about not fulfilling their ideal selves than their duties and responsibilities. The study, which surveyed hundreds of participants, highlights the importance of taking action towards one's ideals rather than waiting for inspiration.
Researchers found cognitive training reduced depressive symptoms and improved brain health in individuals with chronic traumatic brain injury. The study showed significant reductions in depressive symptoms, increased cortical thickness, and improved neural network connectivity.
Scientists have developed a new approach to cancer therapy by combining two synergistic drug components into a dimer, which can be loaded into polymeric nanotransporters at exceptionally high concentration. This method reduces side effects and improves transport and accumulation of drugs in tumors.
Scientists at Virginia Tech Carilion Research Institute have identified a novel cellular mechanism that can lead to cancer metastasis. The researchers found that the formation of gap junction structures allowing cells to communicate was disrupted during epithelial mesenchymal transition (EMT), despite an abundance of connexin 43 proteins.
A University of Oregon study found that fans who feel part of a group experience higher levels of excitement, joy, and engagement, leading to increased sponsor recall and repeat attendance. Fostering this in-group feeling can be achieved by creating welcoming off-site venues and activities.
Researchers aim to enhance neuron protection in glaucoma patients by activating the sigma 1 receptor, potentially increasing long-term protection. The S1R agonists have shown promising results in protecting retinal ganglion cells and may offer a new treatment strategy for glaucoma.
Two studies investigate vitamin D supplementation's impact on infant development, with no significant difference found in bone strength or infection incidence at age 24 months. A systematic review and meta-analysis also explores the effects of prenatal vitamin D on several infant outcomes.
A team of researchers has developed a model that simulates protein evolution, revealing how evolving protein components can give rise to dynamic and efficient molecular machines. The model shows that flexibility allows proteins to bind effectively to other molecules.
A University of Córdoba research group has developed a method to detect pollutants in seawater at very low concentrations, focusing on parabens and triclosan used as preservatives in personal hygiene products. The new system, Lab-on-Valve, uses carbon-coated titanium dioxide nanotubes for efficient detection.
A new analysis found that construction delays contribute 18% to the costs of building new nuclear power plants, making them more expensive than expected. The study suggests that these extra costs make nuclear projects high-risk investments.
A study found that oxytocin and vasopressin reduce aggression and increase cooperation in male rhesus macaques, flattening the social hierarchy and promoting egalitarian behavior. The hormones also synchronize behaviors, enabling non-verbal communication between animals.
Researchers propose strategies to discuss racial disparities, including providing context and emphasizing policies in shaping inequalities. Studies show that simply presenting numbers can cause people to support punitive policies, while offering context and information on history and policy change can reduce disparities.
A team of scientists has created a map of the molecular network in the aging brain, revealing two new Alzheimer's disease target genes that can be deleted or modified to treat the disease. The study provides a unique resource linking molecular changes in nearly 500 older brains to cognition and brain pathology.
A chemical compound called indazole chloride has been shown to produce beneficial inflammation and remyelination in multiple sclerosis patients. This process can help repair damaged axons and restore myelin, potentially reducing disability burden. The findings provide a promising new treatment avenue for the disease.
Research published in Psychological Science found that individuals who engaged in socially-focused strategies experienced increased life satisfaction, whereas those with nonsocial strategies showed no change. Time spent socializing with family, friends, and neighbors was particularly linked to improved well-being.
A team of researchers has discovered that the loss of BMI1 gene expression in the brains and neurons of patients with the common form of Alzheimer's disease is not a consequence of the disease, but rather its cause. This finding offers new hope for developing a cure by targeting the BMI1 gene.
A new compression bandage developed by MIT engineers features pressure-sensing photonic fibers that change color in response to pressure. This allows caregivers to gauge the optimal pressure and adjust the bandage accordingly.
Two new Collaborative Research Centers at Charité will investigate the use of diagnostic imaging technology to visualize pathological changes in the extracellular matrix. This research may contribute to the early detection of diseases and improve therapy monitoring. The centers aim to uncover new insights into memory consolidation and ...
A study published in JNeurosci reveals a new pattern of neuronal activity in the gastrointestinal tract that generates rhythmic electrical activity in smooth muscle. This finding identifies a previously unknown mechanism for colon movement, suggesting an early feature preserved through nervous system evolution.
Researchers at the University of Leeds have developed a new technology to extract anthocyanins from blackcurrant fruit waste for use in renewable dyes. The resulting hair dye is non-toxic, water-soluble and provides great colour results with minimal potential risks.
Researchers have engineered a cell-like structure that harnesses photosynthesis to perform metabolic reactions, including energy harvesting and cytoskeleton formation. This innovation opens up new possibilities for building artificial cells that can mimic complex biological behaviors.
Researchers have developed a novel method enabling infinite walking in VR by manipulating user eye movements during saccadic suppression. The system successfully redirects users away from obstacles in the physical space while avoiding scene distortions.
The Swiss State Secretariat for Migration and the Immigration Policy Lab (IPL) are testing a new data-driven method to assign asylum seekers to cantons across Switzerland. The algorithm aims to maximize job chances, and its recommendations will be compared to those of randomly allocated individuals over several years.
Research reveals that E. coli infection can induce delirium in aging rats by reducing levels of brain-derived neurotrophic factor (BDNF), a protein essential for long-term memory formation. The study suggests that immune system activation, such as after surgery or infection, may contribute to cognitive decline in the elderly.
A study found that serum NF-L concentrations showed promise as a biomarker for brain injury due to repetitive subconcussive head impacts, but further research is needed. The researchers also observed fluctuations in tau protein concentrations, which did not show significant differences between starters and nonstarters.
Researchers at Cold Spring Harbor Laboratory have identified a neural circuit in the amygdala that generates anxiety. The critical role of dynorphin was revealed, which could serve as a cellular target for treating anxiety-related disorders.
Purdue researchers have found a way to overcome the brittle nature of ceramics by applying an electric field during sintering, resulting in materials that can deform like metals at room temperature. This innovation enables the creation of more stable ceramic components for aircraft engine blade coatings and dental implants.
A recent study by Vanderbilt University Medical Center found that quitting smoking significantly reduces lung cancer risk, with a 39% drop in just five years. Even 25 years after quitting, former heavy smokers' risk remains threefold higher than non-smokers.
A preclinical study found that combining soy lecithin with an NSAID increased anticancer properties and reduced gastrointestinal bleeding. The combination provided superior protection against colorectal cancer without the usual side effects, according to researchers at UTHealth.
New research reveals four essential skills for nurse leaders to facilitate successful cross-sector collaborations promoting community cultures of health. Nurse leaders must possess knowledge, attitudes, and skills as facilitators, partners, and relationship-builders to address social conditions affecting population health.
A recent University of Minnesota Medical School study found a direct link between psychosocial stress and shortened lifespan in mice, identifying cellular senescence mechanisms and diseases associated with aging. The research also observed an increased risk of cardiovascular disease, including early-stage atherosclerosis.
Researchers discovered a naturally occurring protein called apolipoprotein A-I binding protein (AIBP) that inhibits inflammatory response underlying chronic pain processing. A single spinal injection of AIBP alleviated chemotherapy pain in mice for two months with no side effects.
Researchers found that SHP2 inhibitors are effective against lung and pancreatic cancers, which share the same genetic error. The new class of drugs may help treat drug-resistant tumors by reverting cancer cells to being susceptible to other drugs.
A new, fully implanted deep brain stimulation device uses real-time brain signals to fine-tune its signaling, reducing side effects and improving symptom control in Parkinson's patients. The adaptive system was shown to be equally effective as traditional stimulation methods in initial short-term studies.
Researchers propose that wars between patrilineal clans led to a collapse in male genetic diversity around 7,000 years ago. This phenomenon, known as the Y-chromosome bottleneck, was observed only in men and has been linked to changes in social structures after farming and herding emerged.
Researchers found that activating olfactory receptor OR51E2 in prostate cancer cells causes aggressive castration-resistant disease, suggesting a new treatment approach. Blocking the receptor with specific molecules or scents could provide a new way to treat prostate cancer.
Aalto University researchers found Nokia's radical strategic renewal was fueled by a culture shift led by the new board, which increased trust and encouraged data-driven decision-making. By presenting multiple options, top managers became less emotionally attached to their initial strategies.
A recent study published in JAMA Pediatrics found that US citizen children whose mothers are eligible for DACA are more likely to participate in the Special Supplemental Nutrition Program for Women, Infants and Children (WIC). The study analyzed data from nearly 2,000 children and their mothers, revealing a significant increase in WIC ...
A 16-week study found that combining recreational football training with dietary guidance significantly improves physical fitness, reduces blood pressure, and promotes healthier weight loss. This innovative intervention demonstrates the potential for exercise and diet to prevent type 2 diabetes in middle-aged and elderly individuals.
The University of Texas at San Antonio is upgrading its storm water management facilities with a low-impact development approach to remove pollutants from storm water runoff. The project will treat runoff from 9.5 acres of campus rooftops and parking lots, reducing contaminants entering the Edwards Aquifer.
A new study finds that male thyroid cancer survivors have a nearly 50% higher risk of developing heart disease than women. Additionally, thyroid cancer survivors with obesity have a 41% higher risk of cardiovascular disease.
Researchers found that growth hormone treatment improved cognition, reduced brain tissue loss, and promoted plasticity in the brain of mice with induced strokes. The treatment showed promise for facilitating rehabilitation and improving quality of life after a stroke.
Researchers at the University of Sydney have developed a generalized method to predict epileptic seizures using data from non-surgical devices powered by AI and machine learning. The system can alert epilepsy sufferers within 30 minutes of the likelihood of a seizure, with an accuracy rate of up to 81.4%.
Researchers at Wake Forest Institute for Regenerative Medicine have created an advanced brain organoid that closely resembles human brain anatomy. This innovation enables faster drug discovery and screening for neurological conditions, as well as improved understanding of the blood-brain barrier.
Researchers identified a genetic link between SuperAgers and better memory retention, suggesting that therapies targeting the MAP2K3 gene could reduce age-related memory decline and Alzheimer's disease risk.
Scientists at Newcastle University successfully printed the first human corneas using a unique gel-like substance and 3D printing technology. The breakthrough could provide an unlimited supply of corneas for transplantation, addressing a significant shortage that affects millions worldwide.
Researchers propose using viruses to restore normal functioning of cells' nuclei, potentially eradicating unwanted effects of aging. Wrinkled nuclear membranes may be responsible for metabolic diseases such as diabetes and fatty liver disease.
Supriya G. Mohile, an oncologist at the Wilmot Cancer Institute, has been named the winner of the B.J. Kennedy Award by ASCO for her work in geriatric oncology. The award recognizes her research and efforts to improve communication between doctors and older patients with cancer.
A new study reveals an invisible layer of biological compounds on the sea surface can reduce carbon dioxide gas exchange by up to 50 percent. This finding has major implications for predicting future climate, as it suggests slower removal of anthropogenic carbon dioxide from the atmosphere.
The UKPID registry has provided valuable information on PID in the UK, especially regarding delays to diagnosis. The data show that longer diagnostic delays can lead to poorer long-term outcomes for patients.
A new Portland State University study found that infant mortality rates are higher in counties with greater proportions of conservative Protestants, especially fundamentalists. The research suggests that the insular culture of fundamentalists can lead to poorer health outcomes.
Researchers from University of Pennsylvania develop a mathematical model to understand the dynamics of cancer growth and spread. The study suggests that mutations leading to metastasis often arise early in tumor history, contrary to previous observations.
The material has unique properties that could be used to guide autonomous vehicles or instruct robots in factories. Liquid crystal shells can reflect light highly selectively and change structure when exposed to certain impacts, enabling passive sensors for pressure and temperature detection.
A research team at Hokkaido University has discovered the key receptor molecule that enhances the infection of the influenza A virus. The Ca2+ channel is the critical component, and blocking it with calcium channel blockers can significantly suppress IAV infections.
A new genetic cause for canine congenital eye disease has been discovered, revealing an unprecedented mode of inheritance linked to maternal genes. The study found that a deletion mutation in the RBP4 gene leads to vitamin A deficiency and blindness in affected dogs.
Cavefish have higher levels of DNA methyltransferase DNMT3B in developing eyes, leading to epigenetic suppression of eye development genes. This process differs from genetic mutations, which are permanent changes in the DNA code.
Researchers propose creating and analyzing new systems governed by entanglement properties directly connected to the original ones, making it easier to quantify experimentally. This innovative approach can be carried out in several experimental conditions, from atomic systems to superconducting circuits.
Researchers found that climate change led to a shift in the host choice of zombie ant fungi, from leaves to twigs and bark, as tropical forests transitioned to temperate areas. The study, published in Evolution, reveals that this adaptation occurred independently in different locations around the world.
Researchers found that proxies more accurately predict length of life left and are less likely to agree to burdensome treatments for residents believed to have less than 6 months left. This discovery was published in the Journal of the American Medical Association Internal Medicine.
A recent study published in the Journal of Minimally Invasive Gynecology found that high volume gynecologic surgeons have significantly lower complication rates compared to low volume surgeons. This is especially concerning for women undergoing complex surgeries such as hysterectomies and gynecologic cancer treatments.