A recent systematic review found that health information exchanges can significantly reduce healthcare costs and usage. Community-based exchanges showed more promising results than proprietary ones. The study's lead investigator attributed the difference to more mature systems being examined in the current review.
Researchers developed a gentle buffer exchange method to remove free ions, enabling DNA origami stability at low-magnesium levels. This breakthrough paves the way for various biomedical uses, including drug and enzyme delivery.
Researchers developed a new neural interface paradigm that preserves dynamic muscle relationships in amputated limbs, allowing for proprioceptive feedback and movement commands. The technique improved sensation and control of prosthetic limbs, enabling people with artificial limbs to move more efficiently and naturally.
Researchers from OSU and NOAA have mapped over 1,000 underwater methane seep sites off the Oregon coast, finding that much of the methane is solidified as hydrates beneath 500 meters. The discovery raises concerns about environmental impact and potential energy sources.
Women with metabolically 'healthy' obesity still face a higher risk of cardiovascular disease, even if they are not experiencing other metabolic issues. A large cohort study found that this group has a 39% increased risk of cardiovascular events compared to normal weight women without metabolic abnormalities.
Researchers created a unified Time-Temperature-Architecture Diagram to guide the fabrication of heterostructures with favorable electronic properties. The blueprint enables the generation of numerous nanostructures with physical properties of interest, paving the way for advancements in computing power and transistors.
Researchers at The University of Tokyo's Institute of Industrial Science have developed a method to integrate living muscle into robots, overcoming previous issues with force and function. The resulting biohybrid robots achieved remarkable movement and continued muscle function for over a week.
A new study found that urbanization and climate change are driving off low-lying morning clouds in southern California, leading to increased wildfire risk. The decrease in cloud cover correlates with lower vegetation moisture and higher fire danger.
A new tool called EcoCast uses satellite data, maps, and observations to help fishers locate the most productive fishing spots while avoiding protected species. The study shows that this approach can be up to 10 times more efficient in protecting species than previous management styles.
Researchers discovered that the root spittlebug produces a thermal insulator-foam to maintain an optimal body temperature during development. The foam, composed of palmitic acid, stearic acid, proteins, and carbohydrates, protects nymphs from temperature fluctuations in the external environment.
Researchers discovered that blood stem cells with a genetic mutation can be compensated by normal stem cells producing specific types of immune cells. Key findings suggest these highly productive stem cells proliferate dramatically and maintain a balanced immune system when transplanted into mice.
Researchers at UTA will work with Boeing to create new learning environments where humans collaborate with bots, robots, and AI. The goal is to reskill employees and prepare them for an increasingly automated workforce.
A study found that smaller societies with female leadership have higher female representation, but still lag behind male representation, indicating a need for constitutional commitments to equality. Academic societies can promote gender equity through supporting female leadership and making an outward commitment of equality.
A recent study published in Risk Analysis found that the public expects self-driving vehicles (SDVs) to be four to five times as safe as human-driven vehicles. To be accepted, SDVs must reduce traffic fatalities by at least 75-80%.
A Finnish-Canadian study found that law firms' professional ethos discourages men from taking parental leave, perpetuating gender inequality. The study suggests organisational solutions and male law firm partners' encouragement are needed to promote a more family-friendly culture.
Researchers have discovered that disruptions in iron-sulfur cluster formation can lead to the buildup of fat droplets in cells, a hallmark of conditions like nonalcoholic fatty liver disease. The study provides clues about the biochemical causes of these diseases and may help researchers find new targets for treatment.
Scientists have engineered new anti-cancer antibodies that attract killer T cells directly to cancer cells covered with the ROR1 protein. These bi-specific antibodies can target several types of cancer and work for about five days, outlasting current approaches.
Researchers found radish cover crops significantly reduced soil nitrate content, but decomposed nitrogen was not returned to the soil. The study suggests radish can trap nitrogen without providing a fertilizer benefit to subsequent crops.
The new guidance, developed by experts at the University of Exeter Medical School, aims to improve quality of life for older adults with type 2 diabetes. For the first time, it provides guidance on stopping treatment in particularly frail adults, a move welcomed by Diabetes UK.
A team of scientists analyzed ant species distributions to understand why biodiversity is higher in the tropics. Their research suggests that time is key to species diversity, with tropical habitats having had more time to accumulate species.
Cesarean-born babies may be at risk for health problems due to differences in their microbiome. A new review suggests that routine antibiotic administration during C-section deliveries is a major underlying problem, rather than a lack of exposure to vaginal microbes.
A new journal series published in the British Journal of Clinical Pharmacology aims to provide insights into European medication-related guidelines. The series, developed in collaboration with the EMA, offers annotated versions of relevant guidelines and regulatory documents, facilitating discussion among professionals and patients. Ex...
Researchers have gained insights into stress granules, clumps of RNAs and proteins that form when cells are stressed, linking them to neurodegenerative diseases. The study reveals the critical role of two enzymes, USP5 and USP13, in disassembling stress granules, which could lead to innovative treatments.
New research from UC Riverside psychologist Kalina Michalska finds that children's experience of pain is significantly influenced by their expectations. The study, involving healthy and anxious children, reveals that simply telling them they will experience pain can actually increase the severity of their pain. In contrast, distracting...
New research finds a causal relationship between whites' attitudes towards welfare and their perceived threatened racial status. Whites who fear losing their socioeconomic standing oppose government anti-poverty programs they perceive as benefiting minorities, while not affecting views on programs benefiting themselves.
Researchers developed a new method to identify microbe food sources using carbon stable isotope ratios, providing insights into microbial communities and their impact on animal and plant health. The technique uses mass spectrometry and software to link microbes with substrates, enabling the study of complex microbial relationships.
Researchers developed a technique to distinguish between natural and synthetic truffle compounds using carbon isotope ratios. The method can reliably detect foods containing synthetic truffle aroma or a mixture of synthetic and natural aromas, helping to fight food fraud.
Researchers developed a new method to detect insect invaders using eDNA, while coral reef studies highlighted the importance of cultural values in conservation. Additionally, designers created fish-friendly architectural engineering designs for marine infrastructure, and a study examined the effects of oil sands on wildlife populations
A global coalition of respiratory doctors and scientists warns of the dangers of e-cigarettes to children and adolescents, citing growing evidence of their addictive nature. The authors call for an immediate ban on flavourings and marketing e-cigarettes as lower-risk alternatives to minors.
The xB3 platform efficiently delivers antibodies across the BBB, maintaining systemic pharmacokinetics and improving brain exposure. The platform demonstrates dose-dependent effects in neuropathic pain models, providing a promising treatment for CNS disorders.
Scientists at the NIH have unraveled the process by which the tularemia bacteria cause disease, finding that it tricks host cell mitochondria in two phases of infection. This understanding could lead to the development of effective treatment strategies for the life-threatening disease.
The European Commission has funded a €4 million research project to develop a new, potentially low-cost class of solar materials. The MAESTRO project will focus on increasing cell stability and boosting efficiency in perovskite-based devices.
Scientists have calculated the axial coupling of neutrons with unprecedented precision using supercomputers, paving the way for more accurate nuclear physics predictions. This breakthrough has significant implications for fields like nuclear energy and nuclear weapon detection research.
A new cooking training program has been shown to decrease sodium levels in Chinese take-out meals without sacrificing taste. The study found significant reductions in sodium content after 36 months, demonstrating the potential benefits of partnering between public health agencies, academic institutions, and community businesses.
Researchers at North Carolina State University have synthesized a new compound inspired by a natural product that is effective against drug-resistant bacteria like MRSA. The molecule, JJM-35, has been shown to be up to 50 times more effective than the original natural product against several bacterial strains.
A Special Focus Issue explores novel LC-MS assays for evaluating DDI potentials early in development, expanding interest in using sensitive and selective assays. The issue discusses multiplexing, HRMS, and sample pooling approaches to improve DDI evaluations.
New research suggests that a narrow corridor along Alaska's Pacific coast could have enabled early human migration to the Americas as far back as 17,000 years ago. The authors used dating and reanalysis of animal bones to reconstruct deglaciation and find that the area was habitable during this time period.
Researchers from Israel and Japan collaborated to diagnose a child with an ultra-rare genetic disease caused by a mutation in the EPT1 gene, which is essential for making myelin in the normal brain. The team found that the disease affects PE production, leading to reduced plasmalogen synthesis, but not enough to prevent myelin damage.
Scientists have discovered that environmental noise can paradoxically maintain the coherence of quantum systems. Researchers at RIKEN Center for Emergent Matter Science used a three-particle system to demonstrate this phenomenon, which could help accelerate research into scaling up semiconductor quantum computers.
Physicists use powerful supercomputers to solve quantum chromodynamics equations, which governs how quarks and gluons interact within neutrons. The new calculation yields the highest-ever precision of nucleon axial coupling, a property that determines the strength of neutron decay into protons.
Researchers found that pigs can ferment fiber in their hindgut without a decrease in efficiency up to 30% inclusion rate. The energy utilization from high-fiber diets is mainly affected by faster passage through the digestive tract, rather than fermentation capacity.
New research found life in the crater within a few years of impact, contrary to predictions. A thriving ecosystem developed within 30,000 years, influenced primarily by local factors such as water circulation and ecological niches.
A new study found that Helicobacter pylori bacteria can shut down the energy production in host cells to evade the immune system, leading to an increased risk of gastritis, ulcers, and stomach cancer.
A $1.7 million NIH grant will aid in understanding citrate signaling for bone development and designing novel biomaterials. Researchers aim to mimic native tissue composition and induce bone growth through citrate-presenting biomaterials.
Researchers at TGen and HCI are working together to combat bone metastatic breast cancer, a leading cause of pain and death for patients. By blocking the activity of RON kinase, they aim to prevent further damage to skeletal structures and enhance anti-tumor immunity.
Researchers at St. Jude Children's Research Hospital have identified a hidden driver, kinases Mst1 and Mst2, that regulates the function of different dendritic cell subsets and primes anti-tumor T cells. This discovery provides clues for new treatment strategies by modulating dendritic cell activity to shape the immune response.
Researchers have developed a novel approach to limb amputation that preserves dynamic muscle relationships, enabling patients to feel the movement of their prosthetic limbs. This new paradigm, called the agonist-antagonist myoneural interface (AMI), has been successfully implemented in a human patient with below-knee amputation.
Researchers found that higher protein intake from most sources was associated with a slightly higher risk of heart failure, with the greatest increase seen for animal-based proteins. The study suggests that moderating protein intake may be beneficial in preventing heart failure, but further research is needed.
Research from the University of Missouri finds that workplace dress codes present a significant barrier to people living with disabilities, leading to increased stigma and decreased confidence. The study highlights the need for inclusive and adaptive clothing options to promote workplace inclusivity.
Researchers at Washington State University have developed a one-step 3D printing process for multimaterial projects, allowing for faster production and reduced manufacturing steps. The technology enables the creation of complex products with multiple parts in one operation, reducing the need for adhesives and joint connections.
Researchers found that official inflation indexes, such as CPI and PCE, may overestimate or underestimate the true inflation rate due to errors in housing rent assessments. The alternative method suggests an error range of 1.7-4.2% during the Great Recession and 0.3-0.9% during the current expansionary period.
Researchers discovered that sharks' electrosensing organs react in an all-or-none manner to tiny electrical fields, unlike skates which respond with graded currents. The study suggests that genes controlling ion channels may be responsible for this difference.
A new review published in Progress in Cardiovascular Diseases found that plant-based diets can prevent and reverse atherosclerosis, reducing the risk of cardiovascular disease by 40%. Plant-based diets are rich in fiber and phytonutrients, which reduce inflammation and oxidative stress, while animal products are high in saturated fat a...
A multidisciplinary team of researchers found that oil and gas wastewater can be effective at suppressing dust, but it also carries high salt, organic, and radioactivity concentrations. The team recommends using alternative materials or treatment to remove contaminants before using the wastewater.
The poll found that only about half of people aged 50 to 80 have set up an account on a secure online access site, or 'patient portal,' offered by their health care provider. Despite the benefits of patient portals, many older adults are uncomfortable with electronic interactions and prefer telephone contact with their providers.
Subtropical Depression Alberto's center has been located near latitude 38.7 degrees north and longitude 87.4 degrees west, approximately 80 miles southwest of Indianapolis, Indiana. The depression is moving toward the north-northeast at 17 mph, with maximum sustained winds near 30 mph and higher gusts.
A team of researchers used powerful supercomputers to calculate the nucleon axial coupling, which is central to understanding a neutron's lifetime. Their method offers a clear path to resolving the experimental discrepancy and provides new insights into fundamental forces of nature.
Researchers at King's College London have discovered a fundamental process by which brains are built, involving the balance of excitatory and inhibitory neurons. This finding may lead to new treatments for neurodevelopmental disorders like autism and epilepsy.
A team of UTSA researchers received a $387,000 grant to develop brain-computer interface technology that identifies brain activity patterns contributing to stuttering. The goal is to train individuals to optimize their brain functions and reduce stuttering rates.
A study found that extreme price competition in the generic pharmaceutical market leads to more manufacturing-related recalls, which may put patients at serious health risk. The researchers suggest that regulators and insurers should temper their pressure on pharmaceutical companies to bring prices down.