Research finds people experience more regret about not fulfilling their ideal selves than their duties and responsibilities. The study, which surveyed hundreds of participants, highlights the importance of taking action towards one's ideals rather than waiting for inspiration.
Researchers found cognitive training reduced depressive symptoms and improved brain health in individuals with chronic traumatic brain injury. The study showed significant reductions in depressive symptoms, increased cortical thickness, and improved neural network connectivity.
Scientists have developed a new approach to cancer therapy by combining two synergistic drug components into a dimer, which can be loaded into polymeric nanotransporters at exceptionally high concentration. This method reduces side effects and improves transport and accumulation of drugs in tumors.
Scientists at Virginia Tech Carilion Research Institute have identified a novel cellular mechanism that can lead to cancer metastasis. The researchers found that the formation of gap junction structures allowing cells to communicate was disrupted during epithelial mesenchymal transition (EMT), despite an abundance of connexin 43 proteins.
A University of Oregon study found that fans who feel part of a group experience higher levels of excitement, joy, and engagement, leading to increased sponsor recall and repeat attendance. Fostering this in-group feeling can be achieved by creating welcoming off-site venues and activities.
Researchers aim to enhance neuron protection in glaucoma patients by activating the sigma 1 receptor, potentially increasing long-term protection. The S1R agonists have shown promising results in protecting retinal ganglion cells and may offer a new treatment strategy for glaucoma.
Two studies investigate vitamin D supplementation's impact on infant development, with no significant difference found in bone strength or infection incidence at age 24 months. A systematic review and meta-analysis also explores the effects of prenatal vitamin D on several infant outcomes.
A team of researchers has developed a model that simulates protein evolution, revealing how evolving protein components can give rise to dynamic and efficient molecular machines. The model shows that flexibility allows proteins to bind effectively to other molecules.
A University of Córdoba research group has developed a method to detect pollutants in seawater at very low concentrations, focusing on parabens and triclosan used as preservatives in personal hygiene products. The new system, Lab-on-Valve, uses carbon-coated titanium dioxide nanotubes for efficient detection.
A new analysis found that construction delays contribute 18% to the costs of building new nuclear power plants, making them more expensive than expected. The study suggests that these extra costs make nuclear projects high-risk investments.
A study found that oxytocin and vasopressin reduce aggression and increase cooperation in male rhesus macaques, flattening the social hierarchy and promoting egalitarian behavior. The hormones also synchronize behaviors, enabling non-verbal communication between animals.
Researchers propose strategies to discuss racial disparities, including providing context and emphasizing policies in shaping inequalities. Studies show that simply presenting numbers can cause people to support punitive policies, while offering context and information on history and policy change can reduce disparities.
A team of scientists has created a map of the molecular network in the aging brain, revealing two new Alzheimer's disease target genes that can be deleted or modified to treat the disease. The study provides a unique resource linking molecular changes in nearly 500 older brains to cognition and brain pathology.
A chemical compound called indazole chloride has been shown to produce beneficial inflammation and remyelination in multiple sclerosis patients. This process can help repair damaged axons and restore myelin, potentially reducing disability burden. The findings provide a promising new treatment avenue for the disease.
Research published in Psychological Science found that individuals who engaged in socially-focused strategies experienced increased life satisfaction, whereas those with nonsocial strategies showed no change. Time spent socializing with family, friends, and neighbors was particularly linked to improved well-being.
A team of researchers has discovered that the loss of BMI1 gene expression in the brains and neurons of patients with the common form of Alzheimer's disease is not a consequence of the disease, but rather its cause. This finding offers new hope for developing a cure by targeting the BMI1 gene.
A new compression bandage developed by MIT engineers features pressure-sensing photonic fibers that change color in response to pressure. This allows caregivers to gauge the optimal pressure and adjust the bandage accordingly.
Two new Collaborative Research Centers at Charité will investigate the use of diagnostic imaging technology to visualize pathological changes in the extracellular matrix. This research may contribute to the early detection of diseases and improve therapy monitoring. The centers aim to uncover new insights into memory consolidation and ...
A study published in JNeurosci reveals a new pattern of neuronal activity in the gastrointestinal tract that generates rhythmic electrical activity in smooth muscle. This finding identifies a previously unknown mechanism for colon movement, suggesting an early feature preserved through nervous system evolution.
Researchers at the University of Leeds have developed a new technology to extract anthocyanins from blackcurrant fruit waste for use in renewable dyes. The resulting hair dye is non-toxic, water-soluble and provides great colour results with minimal potential risks.
Researchers have engineered a cell-like structure that harnesses photosynthesis to perform metabolic reactions, including energy harvesting and cytoskeleton formation. This innovation opens up new possibilities for building artificial cells that can mimic complex biological behaviors.
Researchers have developed a novel method enabling infinite walking in VR by manipulating user eye movements during saccadic suppression. The system successfully redirects users away from obstacles in the physical space while avoiding scene distortions.
The Swiss State Secretariat for Migration and the Immigration Policy Lab (IPL) are testing a new data-driven method to assign asylum seekers to cantons across Switzerland. The algorithm aims to maximize job chances, and its recommendations will be compared to those of randomly allocated individuals over several years.
Research reveals that E. coli infection can induce delirium in aging rats by reducing levels of brain-derived neurotrophic factor (BDNF), a protein essential for long-term memory formation. The study suggests that immune system activation, such as after surgery or infection, may contribute to cognitive decline in the elderly.
A study found that serum NF-L concentrations showed promise as a biomarker for brain injury due to repetitive subconcussive head impacts, but further research is needed. The researchers also observed fluctuations in tau protein concentrations, which did not show significant differences between starters and nonstarters.
Researchers at Cold Spring Harbor Laboratory have identified a neural circuit in the amygdala that generates anxiety. The critical role of dynorphin was revealed, which could serve as a cellular target for treating anxiety-related disorders.
Purdue researchers have found a way to overcome the brittle nature of ceramics by applying an electric field during sintering, resulting in materials that can deform like metals at room temperature. This innovation enables the creation of more stable ceramic components for aircraft engine blade coatings and dental implants.
A recent study by Vanderbilt University Medical Center found that quitting smoking significantly reduces lung cancer risk, with a 39% drop in just five years. Even 25 years after quitting, former heavy smokers' risk remains threefold higher than non-smokers.
A preclinical study found that combining soy lecithin with an NSAID increased anticancer properties and reduced gastrointestinal bleeding. The combination provided superior protection against colorectal cancer without the usual side effects, according to researchers at UTHealth.
New research reveals four essential skills for nurse leaders to facilitate successful cross-sector collaborations promoting community cultures of health. Nurse leaders must possess knowledge, attitudes, and skills as facilitators, partners, and relationship-builders to address social conditions affecting population health.
A recent University of Minnesota Medical School study found a direct link between psychosocial stress and shortened lifespan in mice, identifying cellular senescence mechanisms and diseases associated with aging. The research also observed an increased risk of cardiovascular disease, including early-stage atherosclerosis.
Researchers discovered a naturally occurring protein called apolipoprotein A-I binding protein (AIBP) that inhibits inflammatory response underlying chronic pain processing. A single spinal injection of AIBP alleviated chemotherapy pain in mice for two months with no side effects.
Researchers found that SHP2 inhibitors are effective against lung and pancreatic cancers, which share the same genetic error. The new class of drugs may help treat drug-resistant tumors by reverting cancer cells to being susceptible to other drugs.
A new, fully implanted deep brain stimulation device uses real-time brain signals to fine-tune its signaling, reducing side effects and improving symptom control in Parkinson's patients. The adaptive system was shown to be equally effective as traditional stimulation methods in initial short-term studies.
Researchers propose that wars between patrilineal clans led to a collapse in male genetic diversity around 7,000 years ago. This phenomenon, known as the Y-chromosome bottleneck, was observed only in men and has been linked to changes in social structures after farming and herding emerged.
Researchers found that activating olfactory receptor OR51E2 in prostate cancer cells causes aggressive castration-resistant disease, suggesting a new treatment approach. Blocking the receptor with specific molecules or scents could provide a new way to treat prostate cancer.
Aalto University researchers found Nokia's radical strategic renewal was fueled by a culture shift led by the new board, which increased trust and encouraged data-driven decision-making. By presenting multiple options, top managers became less emotionally attached to their initial strategies.
A recent study published in JAMA Pediatrics found that US citizen children whose mothers are eligible for DACA are more likely to participate in the Special Supplemental Nutrition Program for Women, Infants and Children (WIC). The study analyzed data from nearly 2,000 children and their mothers, revealing a significant increase in WIC ...
A 16-week study found that combining recreational football training with dietary guidance significantly improves physical fitness, reduces blood pressure, and promotes healthier weight loss. This innovative intervention demonstrates the potential for exercise and diet to prevent type 2 diabetes in middle-aged and elderly individuals.
The University of Texas at San Antonio is upgrading its storm water management facilities with a low-impact development approach to remove pollutants from storm water runoff. The project will treat runoff from 9.5 acres of campus rooftops and parking lots, reducing contaminants entering the Edwards Aquifer.
A new study finds that male thyroid cancer survivors have a nearly 50% higher risk of developing heart disease than women. Additionally, thyroid cancer survivors with obesity have a 41% higher risk of cardiovascular disease.
Researchers found that growth hormone treatment improved cognition, reduced brain tissue loss, and promoted plasticity in the brain of mice with induced strokes. The treatment showed promise for facilitating rehabilitation and improving quality of life after a stroke.
Researchers at the University of Sydney have developed a generalized method to predict epileptic seizures using data from non-surgical devices powered by AI and machine learning. The system can alert epilepsy sufferers within 30 minutes of the likelihood of a seizure, with an accuracy rate of up to 81.4%.
Researchers at Wake Forest Institute for Regenerative Medicine have created an advanced brain organoid that closely resembles human brain anatomy. This innovation enables faster drug discovery and screening for neurological conditions, as well as improved understanding of the blood-brain barrier.
Researchers identified a genetic link between SuperAgers and better memory retention, suggesting that therapies targeting the MAP2K3 gene could reduce age-related memory decline and Alzheimer's disease risk.
Scientists at Newcastle University successfully printed the first human corneas using a unique gel-like substance and 3D printing technology. The breakthrough could provide an unlimited supply of corneas for transplantation, addressing a significant shortage that affects millions worldwide.
Researchers propose using viruses to restore normal functioning of cells' nuclei, potentially eradicating unwanted effects of aging. Wrinkled nuclear membranes may be responsible for metabolic diseases such as diabetes and fatty liver disease.
Supriya G. Mohile, an oncologist at the Wilmot Cancer Institute, has been named the winner of the B.J. Kennedy Award by ASCO for her work in geriatric oncology. The award recognizes her research and efforts to improve communication between doctors and older patients with cancer.
A new study reveals an invisible layer of biological compounds on the sea surface can reduce carbon dioxide gas exchange by up to 50 percent. This finding has major implications for predicting future climate, as it suggests slower removal of anthropogenic carbon dioxide from the atmosphere.
The UKPID registry has provided valuable information on PID in the UK, especially regarding delays to diagnosis. The data show that longer diagnostic delays can lead to poorer long-term outcomes for patients.
A new Portland State University study found that infant mortality rates are higher in counties with greater proportions of conservative Protestants, especially fundamentalists. The research suggests that the insular culture of fundamentalists can lead to poorer health outcomes.
Researchers from University of Pennsylvania develop a mathematical model to understand the dynamics of cancer growth and spread. The study suggests that mutations leading to metastasis often arise early in tumor history, contrary to previous observations.
The material has unique properties that could be used to guide autonomous vehicles or instruct robots in factories. Liquid crystal shells can reflect light highly selectively and change structure when exposed to certain impacts, enabling passive sensors for pressure and temperature detection.
A research team at Hokkaido University has discovered the key receptor molecule that enhances the infection of the influenza A virus. The Ca2+ channel is the critical component, and blocking it with calcium channel blockers can significantly suppress IAV infections.
A new genetic cause for canine congenital eye disease has been discovered, revealing an unprecedented mode of inheritance linked to maternal genes. The study found that a deletion mutation in the RBP4 gene leads to vitamin A deficiency and blindness in affected dogs.
Cavefish have higher levels of DNA methyltransferase DNMT3B in developing eyes, leading to epigenetic suppression of eye development genes. This process differs from genetic mutations, which are permanent changes in the DNA code.
Researchers propose creating and analyzing new systems governed by entanglement properties directly connected to the original ones, making it easier to quantify experimentally. This innovative approach can be carried out in several experimental conditions, from atomic systems to superconducting circuits.
Researchers found that climate change led to a shift in the host choice of zombie ant fungi, from leaves to twigs and bark, as tropical forests transitioned to temperate areas. The study, published in Evolution, reveals that this adaptation occurred independently in different locations around the world.
Researchers found that proxies more accurately predict length of life left and are less likely to agree to burdensome treatments for residents believed to have less than 6 months left. This discovery was published in the Journal of the American Medical Association Internal Medicine.
A recent study published in the Journal of Minimally Invasive Gynecology found that high volume gynecologic surgeons have significantly lower complication rates compared to low volume surgeons. This is especially concerning for women undergoing complex surgeries such as hysterectomies and gynecologic cancer treatments.