Researchers found that immune cells in the bloodstream can worsen heart disease when they migrate to the heart. Blocking their migration improved symptoms in mouse models of heart disease, offering a novel therapeutic approach for non-ischemic cardiomyopathy.
A recent study from Johns Hopkins University reveals a flaw in the water treatment process that can create toxic transformation products, including 2-butene-1,4-dial. This compound has been linked to negative effects on human cells and may be responsible for toxicity in cigarette smoke and car exhaust.
A new study at University of Waterloo found that fear of guilt evokes feelings of doubt in decision-making, leading to indecisiveness and repetition in OCD patients. The study's results suggest that addressing this specific factor could improve treatment outcomes for individuals with Obsessive-Compulsive Disorder.
The Tyler Prize honors the groundbreaking research of Dr. Falkowski, which reveals the critical role of tiny phytoplankton in solving climate change. Dr. McCarthy's leadership in global policy initiatives has informed significant climate change policies.
The Persian Gulf may lose up to 12% of its marine biodiversity if climate change is not addressed. Some species may migrate north, but the area suitable for them will shrink under climate change.
Researchers have developed a tiny, simple photoactive film that converts light impulses into electrical signals, stimulating neurons and potentially restoring sight to blind people. The technology uses cheap and widely-available organic pigments and has been successfully tested in experiments with non-functioning retinas.
A study published by The BMJ found no evidence of 'gaming' after death rates for bowel surgeons were publicly reported. However, improvements were seen in mortality rates for patients undergoing non-emergency surgery, suggesting that the introduction of public reporting may have triggered better outcomes through teamwork.
Hawking's final theory on the origin of the universe predicts a simpler and finite universe, contradicting the prevailing theory of eternal inflation. The new theory, developed by Hawking and ERC grantee Thomas Hertog, proposes that the universe is reasonably smooth and globally finite.
A 15-year study found that people taking saunas four to seven times a week were 61% less likely to suffer a stroke than those taking one session per week. Frequent sauna bathing also reduces cardiovascular and all-cause mortality risk.
Researchers use time-lapse video observations to determine the foraging success of Emperor penguins, which is crucial in understanding their diet and adaptability to a warming Antarctic. The study's findings may inform conservation measures to protect the critically endangered species.
Researchers at the University of Birmingham have identified a unique type of immune cell that can combat viral infections. These unconventional V-delta-2 lymphocytes are present at birth and increase in numbers during viral infections, becoming licensed to kill and accessing tissues to detect and destroy virally infected target cells.
A novel voltage signal has been observed in a hybrid metal nanowire-superconductor structure, where the voltage peak appears at the proximity-induced superconducting transition temperature and is proportional to the cooling rate. This finding offers a new method for detecting superconductivity without damaging or dissipating current.
A UH engineer is working to understand how crystals form in soft materials, with potential applications in drug design, biomedical diagnostics and petrochemical production. The researcher aims to control the crystallization process to improve outcomes in various fields.
A study by researchers at the University of Copenhagen has confirmed a connection between the circadian rhythm and aggression in Alzheimer's patients. The team identified a circuit linking the brain's circadian clock to an aggression centre, suggesting a potential target for pharmacological intervention. This discovery may lead to new ...
A recent study suggests that early Mars was modestly warm and prone to rain, with only small patches of ice. The research challenges the long-held idea of an icy climate on Mars.
Research findings show that PD-L1 expression facilitates immune escape in medulloblastoma patients. The study identifies subgroup-specific variations in PD-L1 expression and its relationship with therapeutic responses. Immune adjuvant therapies may be necessary to fully realize the benefits of PD-1 blockade treatments.
A trial found that emollient bath additives provide no meaningful benefit when used in addition to standard eczema care in children. The study included 482 children and found no statistically significant difference in eczema control between the two groups. This may help guide decisions around effective prescribing in this area.
The study shows that using rough particles can significantly reduce the amount of material needed to achieve sudden solidification in suspensions. This could lead to improved cement flow characteristics and potential applications in everyday materials like bullet-proof vests.
A recent study sheds light on the role of inflammation in dementia and Alzheimer's disease, suggesting that inflammation is a major cause rather than just a consequence. The research found that many genes linked to dementia regulate susceptibility and response to inflammatory damage.
Children diagnosed with autism are able to create and play with imaginary companions, but at a later age than typically developing children. The quality of the play is similar, suggesting that imaginary companions could be used in future therapies for autistic youngsters.
Tropical Cyclone Flamboyan has been weakened by strong vertical wind shear, with precipitation pushed southeast of its center. The storm's elongated low-level circulation center is due to the presence of high winds, leading to a gradual decay over the next couple of days.
Researchers recommend developing best practices for revenue sharing, increasing funding for public programs, and establishing professional standards for sharing plant breeding materials. This can support the development of low-return, high-value crops that benefit both farmers and society as a whole.
A Cornell University study suggests that understanding biases is key to resolving conflicts over free speech, as psychological science has shown many types of bias can prevent opposing sides from accepting each other's arguments. The researchers argue that college experiences should involve challenging beliefs, even when uncomfortable.
According to Public Health Ontario and ICES, whooping cough cases in Ontario are more frequent than previously known, with estimated cases being nearly double reported cases. This highlights the need for people to ensure their immunizations are up-to-date to limit potential infection and spread.
Researchers found that Antarctic glaciers can experience surface melting during the winter months due to warm winds. The Larsen C ice sheet shows large meltwater lakes forming, which may affect ice-shelf stability and contribute to sea-level rise if ponds cause ice shelves to break up.
The GPM core satellite analyzed severe weather in the US, predicting a surge of spring tornadoes after a drought. Moisture-laden air from the Gulf of Mexico interacted with dry air, resulting in thunderstorms that spawned rotation and tornadoes.
UT Southwestern researchers have obtained atomic-scale blueprints of the most abundant class of brain nicotinic acetylcholine receptors. The study's findings suggest new ways to treat nicotine addiction and neurodegeneration by designing drugs that interact with the receptor in different ways.
Research at the University of Kent found that 57% of respondents had watched ISIS videos, with 93% reporting a negative attitude towards the group. The study also revealed a 'morbid buzz' surrounding explicit content, making it compelling viewing for many.
The Scripps Research team will expand studies on broadly neutralizing antibodies that can neutralize many strains of malaria and influenza. The grant aims to design promising vaccine candidates against these diseases, which kill millions globally each year.
Scientists have identified thermal energy and low climate stress as key drivers of coral species diversity in the Indian Ocean. The study, published in the Journal of Biogeography, found that optimal levels of warm water and reduced stress support high species richness, while extreme temperatures kill many species.
Researchers have discovered a new material that can absorb and selectively reemit light, providing a platform to understand how information is stored and processed in valleytronics devices. This breakthrough could enable the development of operational valleytronic devices with increased computing power and data storage density.
A recent study from the University of Michigan found that racial disparities in opioid prescribing have decreased, with blacks and whites now receiving equal numbers of opioid prescriptions. However, blacks are at a higher risk of addiction due to prescription narcotic exposure.
A study published in Kidney Cancer found that non-aspirin NSAID use was associated with shorter overall survival time for patients with metastatic renal cell carcinoma. The use of these medications can cause kidney-specific toxicity, leading to increased blood pressure and decreased renal function.
Researchers at Duke University have developed a strategy that delays blindness in mice with retinal degeneration by boosting cells' ability to process misfolded proteins. The approach could potentially be used to prevent cell death in other neurodegenerative diseases, such as Huntington's and Parkinson's.
Researchers from the University of Sheffield have developed an algorithm that pairs wearable sensors with real-life data to monitor MS patients' walking patterns. This innovation helps clinicians assess treatment effectiveness and disease progression, leading to better patient outcomes.
The new technology can control electromagnetic waves in many different ways by adjusting the size and angle of tiny silicon cylinders within a grid structure. This allows for subwavelength control, faster reconfiguration, and potentially improved security scanners and visual displays.
Researchers used human and C. elegans data to understand the mutational causes of cancer, finding a resemblance between nematode worms and human cancer genomes. They discovered DNA mismatch repair deficiencies in both species, providing insights into the causes of cancer and potential treatment avenues.
A study presented at the AATS 98th Annual Meeting found that patients used far fewer opioids than were prescribed after open and laparoscopic hiatal hernia repair. The study identified several factors contributing to over-prescribing, including inadequate patient education and improper use of adjunct pain medications.
A growing financial disparity occurs in couples' financial literacy over time, driven by relationship roles and responsibilities. This can lead to difficulties in managing finances post-divorce or widowhood, as individuals struggle with unfamiliar financial tasks.
Researchers developed a new membrane with nanoscale pores that allows for controlled sweat stimulant release, mitigating issues with direct dermal contact and sweat dilution. The technology has the potential to improve wearable biosensing devices for measuring small samples of sweat.
A study led by Queen Mary University of London found that high-dose vitamin D supplements significantly boosted weight gain in malnourished children. Vitamin D supplementation also resulted in substantial reductions in delayed motor development and language development, with potential implications for the management of severe acute mal...
A global charity grant will support researchers in Australia and the US to identify 'drug-like' molecules for treating malaria. The new treatments aim to target deadly forms of the disease, such as Plasmodium falciparum and P. vivax, with a focus on long-term effectiveness.
Researchers at Joslin Diabetes Center have discovered a hormone in fat that boosts metabolism during exercise and cold exposure. The hormone, 12,13-diHOME, is released from brown fat and offers beneficial metabolic effects. Further studies are underway to understand its role in obesity and metabolic disease.
In a recent study published in JAMA Network, synthetic opioids were found to be involved in 45.9% of opioid-related deaths in 2016, up from 14.3% in 2010. The study highlights the growing threat of synthetic opioids, particularly fentanyl, and their increasing role in overdose deaths
A recent study published in Cell Reports has revealed that mutant Isocitrate dehydrogenase 1 (IDH1) drives glioma development by cooperating with multiple mutations and events in brain tumor cells. This breakthrough discovery provides substantial evidence for the functional role of mutant IDH1 in tumorigenesis.
A study published in Critical Care found that blood type O patients had a death rate of 28% after severe trauma, compared to 11% for patients with other blood types. The researchers suggest that lower levels of von Willebrand factor may be linked to higher hemorrhage rates and increased mortality.
A new study tests the safety and effectiveness of MDMA-assisted psychotherapy in veterans with post-traumatic stress disorder (PTSD), suggesting it may enhance benefits of psychotherapy. However, further research is needed to confirm its efficacy and long-term effects.
Breast cancer screening should be tailored to each woman's risk, considering the benefits and harms of mammography. Experts recommend clinicians engage patients in shared decision-making to determine individualized screening plans.
A new study from Trinity College Dublin found that palliative care significantly improves patient experience by reducing hospital stays and costs. For patients with complex health needs, which often come with high costs, palliative care can expedite discharge and improve outcomes.
A new study found that consumers tend to make choices in a 'boundedly rational' way, relying on predispositions while keeping an open mind to strong evidence. This is particularly true when product quality is ambiguous, such as with generic products versus brand-name alternatives.
A study found that post-mortem CT angiography outperformed conventional autopsy in detecting skeletal and vascular lesions, which can provide crucial information in post-mortem examinations. The technique showed high sensitivity and specificity, making it an excellent choice for investigating traumatic deaths.
The study shows that ST1-ADC selectively inhibits tumor cell proliferation and induces tumor cell death in both in vitro and in vivo ovarian cancer models. The data provide promising results for the development of new therapeutic options to treat ovarian cancer.
A recent study published in the Journal of Allergy and Clinical Immunology found that children living close to major roadways had nearly three times the odds of pediatric asthma compared to those who lived farther away. The researchers also discovered a stronger link between lifetime pollution and asthma among school-age girls.
A recent study found that many academic institutions in the US are unprepared to comply with stricter requirements for clinical trial registration and reporting. The institutions face challenges in allocating staff time and resources to meet these new regulations. As a result, some organizations have not implemented policies to punish ...
A new study published in the American Journal of Clinical Nutrition found that introducing pureed pork as a complementary food to formula-fed infants can support early growth and development. The research suggests that meat-based diets may be beneficial for linear growth, with no increased risk of overweight at 12 months of age.
A study by Yale researchers found significant disparities in lung cancer care and survival between the US and England. In the US, 25% of patients were diagnosed at stage 1, compared to 15% in England, while 45% of US patients were diagnosed late-stage, versus 52% in England.
A network meta-analysis of 53 randomized controlled trials found naproxen most effective in improving both pain and function, followed by cortisone injections and PRP injections. The study suggests naproxen as a relatively safe and low-cost treatment option for knee osteoarthritis.
A new study finds that nurse-led task shifting combined with health insurance coverage is an effective strategy to control hypertension in Ghana. The intervention led to a greater reduction in systolic blood pressure compared to health insurance coverage alone.
The Keck School of Medicine of USC is launching a landmark $1.5 billion National Institutes of Health-led program to develop precision medicine. The program aims to create a demographically, geographically and medically diverse participant community, especially those underrepresented in biomedical research.
A new study reveals that a polydnavirus suppresses the defense mechanisms of both caterpillar hosts and plant hosts, allowing parasitic wasps to thrive. The virus reduces glucose oxidase in caterpillars' saliva, triggering lower enzyme activity and defense-gene expression in plants.