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Science News for September 23, 2018


Results from the COAPT trial reported at TCT 2018 and published simultaneously in NEJM

The COAPT trial found that the MitraClip device significantly reduced hospitalization rates and mortality, while improving quality-of-life measures and functional capacity in heart failure patients with secondary mitral regurgitation. The study also showed a substantial reduction in the need for heart transplants or left ventricular as...

SourceCardiovascular Research Foundation·JournalNew England Journal of Medicine·DateSep 23, 2018

Preventing underage drinking among youths on rural reservations

A recent study evaluated the effects of combined individual- and community-level interventions to reduce underage drinking by American Indian/Alaska Native youths. Reports of drinking frequency declined among students in the intervention group relative to comparison groups, with significant reductions in heavy drinking frequency.

SourcePacific Institute for Research and Evaluation·JournalAmerican Journal of Public Health·DateSep 23, 2018

Prosthetic valve mismatches common in transcatheter valve replacement, ups risk of death

A large study found that severe cases of prosthesis-patient mismatch after transcatheter aortic valve replacement increase the risk of death and heart failure readmissions by 19% and 12%, respectively. The study identified predictors of PPM, including smaller valve prostheses, larger body surface areas, and female or younger patients.

SourceUniversity of Pennsylvania School of Medicine·JournalJournal of the American College of Cardiology·DateSep 23, 2018