Hurricane Florence is approximately 400 miles in diameter, with cloud top temperatures of -80F indicating heavy rainfall capability. The storm has the potential to produce extremely dangerous conditions, including life-threatening storm surges and rainfall exceeding 20 inches in coastal North Carolina.
Researchers at Monash University have discovered structural capacitance elements in mutated proteins associated with human diseases, particularly cancers. These elements enable mutations to trigger a gain-of-function, shedding light on protein evolution and the engineering of highly evolvable proteins.
Researchers present a new continuous model describing self-organized criticality, integrating areas such as economics and developmental biology. The model uses tropical geometry to describe the dynamics of critical systems, providing a universal solution for phenomena like earthquakes and sandpiles.
Experts suggest seven innovative approaches to improve Social Security's adequacy in response to demographic trends. The proposals aim to provide greater protections against financial risk for Americans with increasing longevity, low lifetime earnings, and caregiving responsibilities.
Researchers have analyzed nearly 4,000 mutations in the BRCA1 gene, shedding light on its role in breast and ovarian cancer. The findings provide immediate benefits to patients with previously inconclusive genetic test results, enabling clinicians to better interpret variant of uncertain significance.
A US study found that 59% of partnered men and 51% of women with dementia lived at home were sexually active. However, many faced unaddressed sexual function problems and lacked clear medical guidance. The study aimed to provide normative evidence for informing decisions about sex for people with dementia.
The study highlights the critical ecological roles turtles play in maintaining healthy food webs, dispersing seeds, and creating habitats for other species. The decline of turtles could have far-reaching consequences on ecosystems and human populations.
A Caltech study shows that people can accurately judge a politician's honesty based on their face width. Researchers found that politicians with wider faces were perceived as more corruptible, but it's unclear if they're actually more corrupt. The study suggests that facial appearance may play a role in corruption perceptions.
A study published in BioScience reveals that 61 percent of the world's 356 turtle species are threatened or extinct, which could have ecological consequences. Turtles play a crucial role in maintaining healthy food webs and dispersing seeds, making their decline a concern for ecosystems around the globe.
Researchers at the University of Washington School of Medicine have successfully created a novel, de novo-designed beta-barrel protein that can bind to specific small molecules. The achievement paves the way for custom-designed proteins with precise affinity and functionality.
A systematic review of 25 clinical trials found little evidence that invasive surgery reduces chronic pain. The study's findings raise concerns about the widespread use of these procedures without rigorous testing.
A team of researchers has successfully detected hydrogen using the Extraordinary Hall Effect in cobalt-palladium thin films. The technique demonstrates high sensitivity and could be used to detect leaks in hydrogen-powered vehicles and fueling stations, enhancing gas detection for a clean energy source.
The Max Planck Florida Institute for Neuroscience (MPFI) awards Dr. Jason Christie $2,082,074 to investigate neural circuits in the cerebellum and their role in motor learning. The goal is to understand how neurons interact with each other to facilitate learning outcomes.
A 73,000-year-old drawing made on a silcrete flake in Blombos Cave, South Africa, is the oldest known example of human-made art. The team used various techniques, including microscopy and Raman spectroscopy, to confirm that the lines were applied to the stone.
A new study published in Neurology shows that amyotrophic lateral sclerosis (ALS) affects the mind, especially later in the disease, leading to cognitive and behavioral problems such as apathy, changes in eating behaviors, and loss of sympathy or empathy. People with ALS are recommended to be routinely screened for these issues.
Researchers found evidence of captive jaguar and puma in ancient Mesoamerica, used in rituals and trade networks across the region. Stable isotope analysis suggests some animals originated from distant regions, confirming earlier research on animal captivity and trade.
A study by Rush University Medical Center found that Chicago news media reported 59% of child traffic crash deaths and 38% of fire-related deaths, but not a single case of sudden unexpected infant death. This lack of reporting contributes to parents' unawareness of the risks involved, leading to unsafe sleep environments.
Scientists have created a non-invasive instrument that uses optical trapping and Raman spectroscopy to study individual cells in real-time. The technique allows for the analysis of cell interactions and molecular differences without damaging or labeling the cells.
Scientists have uncovered how mice ignore their own footsteps, offering insights into human speech and music learning. The study shows that mice develop an adjustable sensory filter to suppress movement-related sounds, improving sound detection in their environment.
A new study by UCSF researchers reveals that nearly one in seven older veterans with hypertension are discharged with increased blood pressure medications despite having well-controlled blood pressure prior to their hospital stay. The study suggests a potential risk of medication harm due to overtreatment, particularly among older adults.
Astronomers are probing the mystery of how galaxies stop forming stars by studying a class of galaxies known as 'self-quenching' galaxies. These galaxies have gas being blown out at incredible speeds, but without evidence of black hole activity, suggesting alternative mechanisms may be at play.
Young footballers would benefit from more time learning to read the field and less on ball skills. Research suggests scanning should be taught alongside technical and tactical skills to improve awareness, decision-making, and technical actions. Coaches with higher qualifications and experience tend to prioritize scanning.
Researchers have developed a new sensor that uses the mbira instrument to detect toxic substances and counterfeit medications. The sensor can distinguish between different liquids by their density, making it a potential tool for detecting counterfeit medication.
People who use drugs in NYC have changed their behaviors to prevent overdoses due to the increasing presence of fentanyl. Many reported using test shots and carrying naloxone, while others used drugs with others or reduced their consumption.
Researchers have identified mutations defining two common subtypes of MPAL, B/myeloid and T/myeloid, and shown that some patients may benefit from targeted therapies. The study provides a genetically based framework for designing clinical trials to develop more effective treatments.
A study by UC Riverside researchers found that male mice on high-fat diets experienced neuroinflammation and reduced testosterone levels, while female mice remained protected. The findings suggest ovarian estrogen plays a crucial role in protecting females against weight gain and associated health issues.
A recent study from the University of Chicago Booth School of Business found that uncertain rewards motivate consumers to make repeat purchases. This phenomenon is attributed to the psychological boost consumers receive in moving from uncertainty to certainty resolution.
Researchers at Toyohashi University of Technology have discovered a new ultrasonic wave phenomenon that enables precise and nondestructive detection of fatigue and early damage in thin plate materials. This technology surpasses conventional methods, allowing for accurate evaluation of material damage even before it occurs.
Researchers at Sanford Burnham Prebys Medical Discovery Institute have found that amodiaquine suppresses blood vessel formation through both the apelin and VEGF pathways, reversing vascular eye damage in animal models. The compound blocks the receptor's function by binding to a unique area, inhibiting apelin's ability to drive blood ve...
A randomised controlled trial found that high dose folic acid supplementation beyond the first trimester has no benefit for preventing pre-eclampsia. However, low dose folic acid supplements before and during early pregnancy are still strongly recommended to prevent birth defects such as spina bifida.
Researchers aim to understand how individuals protect their personal data in the digital age. The new study will develop survey instruments and conduct qualitative fieldwork to identify different strategies for navigating algorithmic privacy. It also plans to create experimental prototype tools to explore the design space around algori...
Researchers have discovered a new combination treatment targeting pre-leukemia stem cells by inhibiting protein synthesis and oxidative phosphorylation pathways. The treatment, involving FDA-approved drugs omacetaxine and venetoclax, has shown promising results in killing cancerous cells while leaving healthy stem cells unharmed.
Researchers at the University of Basel have developed a new technique to probe individual edge states in novel materials, such as topological insulators and 2D materials. This allows for precise measurement of current-carrying edge states with nanometer resolution.
A synergistic approach to big data in science emphasizes the importance of collaborative research efforts and open science. Ecologists must work together to answer complex, globally relevant questions that cross disciplines and require extrapolating findings from one location to another.
Future El Niño and La Niña events are expected to cause more intense temperature and precipitation changes, including increased wildfire risk in the Southwest US. Climate model simulations suggest that these events will become even cooler and wetter in California, exacerbating flood risks.
LumaCyte's Radiance instrument offers rapid analysis of viral vaccines, speeding up development and production. This label-free method provides real-time monitoring of viral infectivity, reducing the time required to obtain an answer from 72 hours to just 5-10 minutes.
Scientists monitored hurricane water vapor to gauge potential for intense rainfall; analysis shows coldest cloud top temperatures reaching -70 degrees Fahrenheit. Forecasts predict storm weakening and shifting trajectory over the next few days.
A new study identified 'signposts' on cancer cells that can help the immune system recognize and kill them, potentially leading to higher recovery rates. The findings suggest a highly personalized approach to immunotherapy could improve treatment outcomes.
A study found that spring is arriving early in 76% of US National Wildlife Refuges, but not uniformly across migratory bird routes. The team's analysis suggests that higher latitudes are advancing more rapidly than lower latitudes, threatening the synchronization of species with their habitats.
A comprehensive review of research found a significant association between childhood adversity and impaired social cognitive functioning among adults with major psychiatric disorders. The study highlights the importance of understanding the mechanisms behind early trauma and its effects on social cognition, which may inform the develop...
A new screening tool at UBC evaluates online health ads for deception by assigning points based on persuasion techniques used. The tool found that bodybuilding, medicinal products, and lifestyle ads are most common deceptive types.
A mathematical model developed by international researchers predicts that temperature-dependent phages can affect the spread of melioidosis in Southeast Asia. The study reveals opportunities for disease control, including rescheduling work on rice fields and using protective gear during high-risk periods.
A study by UC Riverside researchers predicts climate-induced reduction in large soil pores, leading to increased surface runoff and erosion. Climate change may also exacerbate flash flooding, threatening human health, food security, and biodiversity.
Theoretical analyses show that different motor proteins moving on the same filament can block each other's motion, leading to patterned distributions and emergent topological hindrance. This phenomenon was not previously modeled, but is now understood through a new theoretical model developed by LMU physicists.
A new study suggests that global coastal wetlands can migrate further inland to secure their future and avoid catastrophic losses. The research finds that with enough space, coastal wetlands could gain up to 60% in elevation, mitigating the impact of sea level rise on global warming and coastal flooding.
Researchers developed a mathematical model to predict the spread of melioidosis in Southeast Asia, highlighting the impact of bacteriophages on bacterial populations. The study found that phage-free bacteria numbers are highest during cooler periods, and using fertilizers can kill off phages, posing a risk of more frequent infections.
Researchers and regulators have conducted an expedited analysis of recalled blood pressure drugs, finding no association between use of potentially contaminated products and increased short-term cancer risk. However, a slightly increased risk of colorectal and uterine cancers was found in patients exposed to the impurity NDMA.
The National Science Foundation INCLUDES program aims to create a diverse STEM workforce. RIT professor Casey Miller will direct the Inclusive Practices Hub to enhance diversity, equity, and inclusion in STEM Ph.D. programs.
Researchers at the University of Illinois Chicago developed a nano-sandwich technique to improve heat transfer between two-dimensional materials and silicon bases, reducing component failure due to overheating. By adding an ultra-thin layer of aluminum oxide, they were able to double energy transfer between the materials.
The Global Consortium on Climate and Health Education (GCCHE) has launched an online knowledge bank with resources for educators on the health impacts of climate change. The platform features links to publicly available online courses, curricular guidance, and information on upcoming events.
Researchers demonstrate spontaneous time-reversal symmetry breaking in a cavity quantum electrodynamics system using dipole interaction. Exceptional points are identified at critical thresholds, exhibiting robust dynamics and topological protection.
A systematic review found that serotonin-noradrenaline reuptake inhibitors can cause withdrawal symptoms when discontinued, with venlafaxine showing higher prevalence rates. These symptoms typically occur within a few days of stopping the medication and can last several weeks.
The article tackles key questions about graduate school, including choosing a research program and advisor, and overcoming obstacles like burnout and unexpected setbacks. It provides a roadmap for navigating the chemistry graduate school experience, drawing on stories from students and expert advice.
A team of researchers successfully recorded environmental data using a wireless photonic sensor resonator with a whispering-gallery-mode architecture, mapping temperature distribution on a drone and recording real-time air temperature data. The findings demonstrate the potential applications of miniature sensors in IoT.
The European Renewable Energy Directive may lead to vast new cutting of the world's forests as a result of additional wood needed just to supply 5 percent of Europe's energy. This is expected to increase greenhouse gas emissions by 10 to 15 percent in Europe's energy use by 2050.
ANP32A protein protects cartilage from oxidative stress, which contributes to osteoarthritis development. Antioxidant treatments like NAC may prevent further cartilage damage and reduce osteoarthritis symptoms.
Researchers at Indiana University are leading an experiment that could shed light on the existence of matter in the universe. The project aims to detect a small separation of electrical charges in neutrons, which would validate theories about the imbalance between matter and antimatter.
Researchers from University of Otago identify genetic variant that controls urate levels and gout risk in the gut as well as kidney. This discovery has significant implications for developing new medical interventions in gout and kidney disease.
Former Tropical Storm Paul has weakened to a remnant low-pressure area about 1,115 miles west of Mexico's Baja California, as observed by NASA's Aqua satellite. The system is expected to gradually weaken over the next several days.
A new sensor based on a 3,000-year-old African musical instrument can detect adulterated or counterfeit drugs. The device measures the density of any liquid, revealing whether it has the same ingredients as a known product.