A nationwide study found patients with diabetes discharged with low glucose values have a higher risk of death and rehospitalization; physicians should avoid discharging patients until glucose levels are above 100 mg/dl
Researchers analyzed postmortem brain samples from 24 people with Alzheimer's and 24 without the disease to identify cellular pathways affected by the disease. The study found that axon myelination is disrupted in patients, and gene expression patterns vary significantly between men and women, suggesting potential new drug targets.
A new study suggests that vaccination could reduce the impact of white-nose syndrome in bats by providing immunity against the fungus Pseudogymnoascus destructans. Bats immunized against Pd were less likely to develop WNS or die from the disease in two initial scientific trials.
Researchers investigated risk factors for melanoma dissemination and the impact of time on distant relapse. The findings provide valuable information for improving melanoma treatment outcomes.
In a touchscreen-based task, wolves behaved more prosocially towards their fellow pack members than dogs. Wolves opted to deliver significantly more food to an adjacent enclosure when it held a member of their own pack present.
A new study by University of British Columbia researchers found a correlation between excessive engagement with loot boxes and measures of problem gambling, but not problem video gaming. Loot box use was associated with risky gambling behaviours, suggesting that the feature may be contributing to gambling-like problems in gamers.
A new physical mechanism erodes seabed sediment at depths up to 20 meters, adding nutrients stirred by breaking surface waves. This process complements littoral drift and has significant implications for coastal sediment management practices like dredging.
Two new urine tests have shown promise in accurately detecting bladder cancer, determining its severity, and detecting recurrence. The tests use a gene variant called V1, which is elevated in bladder cancer, and have been found to be 90% effective at detecting the disease.
An international team of scientists has secured a five-year, $6.2 million grant to study HIV and tuberculosis (TB) coinfection in children. The researchers will investigate the disease mechanisms and explore potential therapeutic approaches using nonhuman primate experiments.
Scientists investigate how tropical species are adapting to the newly formed pass in St. Joe Bay, a critical ecosystem with seagrass meadows and diverse marine life. The research aims to understand potential changes in seagrass consumption and its impact on juvenile fish, crabs, and shrimp.
Researchers found the Great Whirl, a massive whirlpool off East Africa, is larger and longer-lived than previously thought. It can grow to over 275,000 square kilometers in area and persist for about 200 days.
The Dementia Friendly Hospital Initiative targets comprehensive training for all hospital staff to improve quality and safety for patients with dementia. The program aims to lower rates for in-hospital injuries, length of stay, and 30-day readmissions.
A study by the University of Saskatchewan found that therapy dog visits can significantly improve the comfort levels and positive feelings of hospital waiting patients. The study showed a noticeable reduction in distress levels and an increase in perceived comfort among patients, regardless of wait time duration.
Researchers discovered that tumors subvert endothelial cells' ability to form new blood vessels, using microRNA to control gene expression. Delivering this microRNA to endothelial cells in mice slowed tumor growth and reduced blood vessel formation.
A new reading of the Mesha Stele suggests that biblical King Balak may have been a historical figure, based on high-resolution images revealing three consonants in the monarch's name. The name is now believed to be 'Balak', a king of Moab mentioned in the biblical story of Balaam, rather than the previously accepted 'House of David'.
Researchers at Cornell University discovered a link between diabetes and increased risk of metastatic cancer, attributed to the glycation of collagen matrices. Elevated blood sugar levels lead to structural changes in collagen fibers, facilitating cancer cell movement through the body.
Researchers found that MDM2 interacts with a mitochondrial protein to promote cancer cell death. Nutlin-3A enhances this interaction, helping kill cancer cells.
Researchers have developed a computational approach to simulate the complex bioelectrical interaction at the tissue scale, enabling more accurate and capable virtual experiments of cell behavior. The technique has potential applications in treating cancer and accelerating combat wound healing.
Researchers from NYU Tandon School of Engineering have developed models to assess pollution exposures at the neighborhood level, but propose advancing to individual-level assessments using data from environmental sensors, mobile, and wearable devices. This could provide evidence-based arguments for change, particularly impacting indivi...
Researchers at Harvard University have developed a new tool that records and controls neural activity in real-time using genetically encoded voltage indicators. This breakthrough enables the study of complex behaviors and neural interactions with unprecedented clarity.
Researchers measured farmland nectar supplies throughout the year, revealing hungry gaps when food supply is not meeting pollinator demand. Early spring and late summer are periods of great nectar deficit on UK farmland.
A large study found that quitting cigarette smoking is associated with a reduced risk of bladder cancer in postmenopausal women. The risk continued to decrease after 10 years of quitting, but even after 30 or more years, risk remained higher for those who had smoked than never-smokers.
Researchers found a new pathway to killing cancer cells by targeting ferroptosis, a type of cell death linked to immune cells. The study suggests that combining ferroptosis sensitizer and checkpoint inhibitor treatments creates a strong immune response that fights tumors.
Research suggests that daily activities such as eating and walking are affected early in the course of rheumatoid arthritis, with most patients experiencing functional disabilities. The study also found that persistent excess in functional disability continued even after diagnosis and treatment.
Researchers at Oak Ridge National Laboratory developed a stretchy plant-derived material with superior adhesion properties, while also advancing additive manufacturing techniques for metal parts. Additionally, they utilized the Summit supercomputer to simulate small modular nuclear reactor designs with improved efficiency.
Researchers repurposed shrink films to make strong grippers that can encapsulate materials or be incorporated into soft robotics. The grippers were made by patterned black ink onto polystyrene sheets, which then wrapped around objects to grip them.
Researchers discovered that neutrophils can induce a previously unrecognized type of cell death in tissues, leading to the destabilization of atherosclerotic plaques. This process causes inflammation, which increases the likelihood of plaque rupture and subsequent cardiovascular events.
The largest study of its kind has identified 190 links between genetic code and birth weight, with two-thirds being discovered for the first time. Both maternal and fetal genetic effects play a role in influencing birth weight, with some genes promoting growth while others restrict it.
Researchers are developing novel derivatives of glucagon to improve rescue kits for hypoglycemia, which can be life-threatening if left untreated. The new solutions aim to enable easy delivery methods like an EpiPen-like device and potentially intranasal delivery.
Researchers at Johns Hopkins Medicine have developed a technique that facilitates precise placement of cancer drugs in the brain using positron emission technology and image-guided drug delivery. This approach shows promising results in improving treatment outcomes for difficult-to-treat brain cancers, such as glioblastoma.
Research found that nematode-infected horned passalus beetles process wood 15% faster than uninfected ones, leading to increased decomposition rates. The parasites are beneficial to the forest ecosystem, enabling the beetles to provide a more effective service
Researchers at the Montreal Clinical Research Institute have made a breakthrough in understanding how neurons navigate to their targets, potentially leading to treatments for spinal cord injuries and motor disorders. The study discovered that Sonic hedgehog molecules act like breadcrumbs to guide axons towards specific locations.