Nanobodies have been isolated and made available for researchers to study the 'spike' protein of SARS-CoV-2 virus. These proteins can stabilise the 'spike', enabling better imaging at an atomic scale, which could lead to new diagnostics and treatments.
Researchers discovered that PHIP protein resides at the leading edge of GBM cells, enabling other adhesion proteins to deepen the grip of cancerous cells on healthy brain tissue. Suppressing PHIP helped inactivate proteins that form the machinery for tumor cell movement, driving aggressive behavior.
SourceSutter Health·JournalProceedings of the National Academy of Sciences·DateApr 18, 2020