Researchers developed a simple blood test that measures the body's immune response to improve ovarian cancer diagnosis. The test uses an immune marker for inflammation and cancer markers to detect epithelial ovarian cancer in blood, with results validated across two separate human trial cohorts.
A new study has found that the guideline-recommended diuretic chlorthalidone causes more serious side effects, including hypokalemia and kidney problems, compared to hydrochlorothiazide. The study analyzed data from over 730,000 individuals treated for hypertension.
A study found that reducing animal product intake and following a primarily plant-based diet can decrease the risk of heart disease by minimizing the adverse effects of a gut-microbiome associated with increased risk of coronary heart disease. Higher TMAO levels were linked to a 67% higher risk of CHD.
Researchers found that Earth's oceans already contain just the right amount of iron, making it unlikely to improve carbon dioxide absorption. Phytoplankton growth is more dependent on organic compounds called ligands, which regulate iron availability.
Scientists have discovered a new microscopic process called optical intersite spin transport (OISTR) that allows light to trigger a displacement of electrons between atoms, influencing the local magnetization. This process is accompanied by a leveling of electron reservoirs and can be tailored by bringing together specific types of atoms.
A new study of wild chimpanzees finds that males whose mothers were present during their tween and teen years had higher odds of survival later in life. The study also suggests that adolescent males benefit from their mother's wealth of experience and knowledge, such as how to avoid predators or find food.
Researchers identified precisely which mouse is making which sound in a study published in Nature Neuroscience. Mouse calls are different depending on the position of the mouse and relate to dominant signals.
The NRG-CC001 trial found that lowering radiotherapy dose to hippocampal stem cells reduces cognitive toxicity and neurologic symptoms in patients with brain metastases. Patients who received whole-brain radiotherapy with hippocampal avoidance reported improved cognitive function, reduced fatigue, and fewer cognitive symptoms.
A team developed new hydrogen evolution photocatalysts (HEPs) made from two semiconducting materials, enhancing energy storage. The HEPs absorb more visible light, increasing hydrogen production rates an order of magnitude beyond current single-component inorganic HEPs.
A systematic review of 149 studies has identified 24 genetic variants that increase the risk of endometrial cancer by up to 3.16 times. The study provides a polygenic risk score for personalized risk assessment, facilitating targeted screening and prevention strategies.
Researchers at Karolinska Institutet have discovered a gene, Synaptotagmin 13, that protects against motor neuron degeneration in ALS and SMA. Gene therapy was shown to increase life expectancy in animal models.
A new collaborative study has developed a way to measure microscopic axons using MRI, revealing unprecedented accuracy and opening up new research possibilities. The method overcomes the long-standing challenge of probing axons non-invasively inside a living brain.
A Rice University study found that public school students have healthier core strength than home-schooled children due to daily use of heavy backpacks. The research also revealed a disparity in push-up performance between the two groups, with public school students meeting requirements and home-schoolers narrowly missing them.
Researchers developed a novel method to analyze chemotherapy-resistant tumors using circulating tumor cells. Single-cell RNA sequencing revealed gene expression differences between individual cells, providing insight into the evolution of multiple resistance mechanisms.
A new study found that testing enhances both memory and the ability to make inferences about subject matter. The researchers tested participants with either rote restudy or testing, and found that testing improved long-term memory and inference over a period of 25 days.
A new form of imaging modality called coded light-sheet array microscopy (CLAM) allows for full 3D parallelized fluorescence imaging without scanning. CLAM reduces photobleaching and preserves biological specimen viability, enabling long-term volumetric imaging.
Researchers at Otto-von-Guericke-Universität Magdeburg are using brain research methods to analyze artificial neural networks and improve explainable AI. The Cognitive neuroscience inspired techniques project aims to understand the internal processes of ANNs and identify malfunctions.
A study reveals that Mediterranean-like climates are experiencing variable responses to climate warming, with some regions drying faster than global-mean warming. The differences result from distinct regional changes in atmospheric circulation driven by separate fast and slow sea-surface temperature responses to greenhouse gases.
Researchers have demonstrated the ability to break reciprocity in acoustic waves using spacetime-varying metamaterials. The materials' properties change simultaneously in time and space, allowing for non-reciprocal wave behavior. This breakthrough has potential applications in fields like communications, medicine, and electronics.
A recent study by Jackson Lu, Richard Nisbett, and Michael Morris found that East Asians are disproportionately underrepresented in US leadership positions due to relatively lower assertiveness. The research suggests that diverse leadership styles are valuable for organizations and highlights the need for recognition of these differences.
A new study identifies a strong cancer driver gene linked to alternative splicing changes in aggressive cancers. The researchers developed computational tools and biological model systems to analyze RNA sequences from nearly 900 prostate tissue samples, revealing over 13,000 alternative splicing events.
A team of NUS researchers identified a novel protein S1P2 that can protect nerve cells from damage and pain when activated with a drug-like compound. This discovery holds promise for the prevention and treatment of chemotherapy-induced neuropathy, as well as other forms of neuropathy.
A new study from Columbia University Irving Medical Center found that women who sleep poorly tend to overeat and consume lower-quality diets. Women with poorer sleep quality consumed more added sugars, calories, and unhealthy fats, while those with insomnia symptoms ate more food by weight.
Noninvasive magnetographic imaging of muscle activity allows spatial and temporal mapping of physiological electric currents, enabling studies of the cardiac cycle and lower back pain. This breakthrough method offers diverse applications in medical research and could provide new insights into muscle function and pain mechanisms.
Researchers developed an optogenetic method called mRNA-LARIAT to control mRNA position and translation in living cells. The technique uses blue light to trap specific mRNAs, reducing protein synthesis and cell motility.
Scientists developed SR-FACT microscopy, combining label-free ODT and two-dimensional fluorescence microscopy to visualize cellular environment. The technique revealed novel subcellular structures like dark-vacuole bodies interacting with organelles.
A new artificial neural network model has been developed to solve inverse problems, demonstrating accuracy comparable to the maximum entropy (MaxEnt) approach. The model's versatility and robustness against noisy data have been showcased in various tests, including recovering electron single-particle spectral densities.
The Swedish Malaise Trap Project has documented 20 million insects collected over 15 years, providing a unique timestamp of the country's insect fauna. The project has identified over 1,300 new species and 87 previously unknown to science.
New research suggests that rising sea surface temperatures and acidic waters could eliminate nearly all existing coral reef habitats by 2100. The study found that few to zero suitable coral habitats will remain by 2100, with only small portions of Baja California and the Red Sea being viable locations for coral reefs.
A new RAND Corporation study found that about 12% of young adults surveyed were aware of heated tobacco products and 5% reported using them. The devices are being promoted by the tobacco industry as alternatives to cigarettes.
A new study reveals wide state-by-state variation in melanoma rates attributed to ultraviolet radiation, with highest rates found on the East and West Coasts. States like Hawaii, Utah, Vermont, and Minnesota have high UV-attributable incidence rates, likely due to outdoor activities and sun protection.
Scientists from China's top research institutes discovered the novel coronavirus responsible for the Wuhan pneumonia epidemic through next-generation sequencing and bronchoalveolar lavage fluid samples. The virus is 99.8-99.9% similar among all patients' samples, closely related to bat SARS-like CoVs.
A study by Toni Rodon and colleagues found that areas near former concentration camps in Germany receive more electoral support for far-right parties. The researchers suggest that the 'satiation hypothesis' may explain why this relationship ceases to be significant when the Alternative for Germany party is included in the analysis.
Researchers at McGill University have discovered at least nine directions of brain-gender variation using a unique dataset and machine learning algorithms. This finding has important consequences for promoting equity, diversity, and inclusion in Canada and beyond.
A team of scientists using the Low Frequency Array (LOFAR) radio telescope has detected radio waves from exoplanets interacting with their star's magnetic field, which can heat and erode a planet's atmosphere. The discovery paves the way for novel ways to probe exoplanet environments and determine habitability.
A new study reveals that patients' ratings of hospitals are more closely tied to hotel-like amenities and services than medical care quality. Hospitality scores have a limited impact on patient survival rates, while factors such as nurse responsiveness and room tidiness have a greater influence on satisfaction.
A team of Virginia Tech researchers has developed a new wearable analyzer to measure hazardous air pollutants in real-time for truck drivers and other workers. The device, called iWAVE, provides a time-resolved measurement of exposure and is expected to revolutionize the way workers combat harmful pollutants on a daily basis.
A study on wild bighorn sheep suggests that male offspring may lead to a faster decline in reproductive success and aging rates in mothers. Females that produced more male than female offspring early in life experienced reduced winter survival rates among their offspring, contributing to accelerated maternal aging.
A study by Michigan Medicine team discovered that repeat expansions cause neurodegenerative diseases but also found normal functions of these repeats in regulating protein production in healthy nerve cells. The research suggests a potential pathway for treating Fragile X syndrome and other disorders.
Researchers at KAIST have developed a long-lasting and economical catalyst that converts greenhouse gases into hydrogen gas and fuel. The catalyst, made from nickel, magnesium, and molybdenum, can work efficiently for over a month without degrading.
Research by University of Kent found that moderate intensity exercise, such as brisk walking or cycling, significantly benefits long-term memory performance. The study suggests that moderate exercise is a more effective approach than highly strenuous exercise for improving memory.
Researchers at UC San Diego developed a new ultra-low power Wi-Fi radio that consumes just 28 microwatts of power, enabling IoT devices to communicate with existing Wi-Fi networks. The chip can transmit data at a rate of 2 megabits per second over a range of up to 21 meters.
A team of archaeologists and Traditional Owners identified 10 plant foods, including fruits, nuts, roots, and palm stem, preserved as charcoal at the Madjedbebe archaeological site. The discovery provides insights into the complex lifestyle of the earliest Australian Aboriginal people.
Researchers at the University of Helsinki confirm existence of the Taita mountain dwarf galago, a tiny nocturnal prosimian weighing 100-180 grams. The species is found in relatively cool montane forests and communicates using distinctive calls.
Women who have experienced domestic abuse appear to be more than 40 per cent more likely to die from any cause compared to the general population. The researchers found an increased risk of developing cardiometabolic diseases such as cardiovascular disease and type 2 diabetes in those who have experienced abuse.
A 784,000-year climate simulation reveals that Southern Ocean sea ice significantly reduces atmospheric carbon dioxide during glacial periods. By limiting surface water exposure and vertical mixing of deep ocean waters, sea ice drives a 40 ppm reduction in atmospheric CO2 levels.
Early symbolism in modern humans evolved to become easier to remember and replicate, as shown by experiments using engraved ochre and ostrich eggshell fragments. Participants more accurately recognized young patterns than old patterns, suggesting aesthetic intention behind the creations.
A new intercalation strategy boosts superconductivity in layered materials, enabling tailored topological properties. The method, developed by Tsinghua University researchers, shows enhanced superconductivities and good sample stabilities in intercalated MoTe2 and WTe2.
The 'Birth Settings' report highlights medical disparities in childbirth, with Oregon emerging as a leader in integrated care and access to midwives. Midwife-led births are associated with lower complication rates and improved patient experiences, but US regulations limit access to care.
Scientists at Tokyo University of Science have developed a novel technology to measure thermal energy conversion efficiency. This innovation can shed light on the processes of energy-converting systems like leaves during photosynthesis, improving the understanding of energy transfer in plants and solar cells.
Researchers at MDC have found a weakness in the most common form of kidney cancer by identifying stem cells that depend on two critical biochemical signals. Blocking these signals hinders tumor growth in several laboratory models, suggesting a promising new approach to treating human patients.
Scientists at Virginia Tech explore a novel approach to treat alcohol use disorder by using behavioral analysis and neuroimaging to understand decision-making processes. By pre-experiencing future events, individuals can mentally construct how they will feel, reducing the value they place on alcohol.
Scientists discovered that all materials develop identical statistical properties when exposed to mechanical deformation, leading to self-affine surface roughness. This finding explains the observed universality of surface roughness across different scales and materials.
A team of European scientists developed a micro-particle size analyser using AI and consumer electronics. The device measures particle size with precision comparable to commercial light-based analysers, but is much smaller, lighter, and cheaper.
Researchers have developed a new supercapacitor that combines high power density and energy density, enabling fast charging and long runtime. The device can be bent to 180 degrees without compromising performance, making it ideal for wearable electronics and electric vehicles.
A study found that low-dose methotrexate was associated with a small increase in adverse events, such as skin cancer and gastrointestinal problems. However, the risk for kidney-related side effects was decreased. The findings suggest that monitoring guidelines and safe prescribing of LD-MTX may need to be revised.
Researchers found that B cells migrate to multiple brain areas after a stroke, targeting regions critical for motor and cognitive recovery. The discovery could lead to new therapeutic avenues for stroke patients.
Researchers at Binghamton University found that road salt and invasive species can harm native amphibians, with non-native African clawed frogs showing greater tolerance to chemical changes. This study highlights the need for better environmental management strategies to protect natural ecosystems.
Researchers identified reduced brain activity in a specific left-brain area in individuals with face blindness, contrasting with normal activity in control subjects when viewing faces. The discovery provides new insights into the condition and may aid in developing treatments.
Scientists have determined the 3D atomic structure of a key enzyme complex in paramyxoviruses, a family of RNA viruses that includes measles, mumps, human parainfluenza and respiratory syncytial virus (RSV). This discovery could lead to the development of new antiviral drugs for these viruses as well as coronavirus.