Researchers at the University of Cincinnati found that a strain of E. coli Nissle protects human cells against pathogenic E. coli bacteria. The study suggests that Nissle may be used to develop a treatment for E. coli infections, which affect millions annually.
Two studies found that methotrexate treatment does not increase the risk of chronic interstitial lung disease in RA patients, but may even delay its development. This is significant as ILD is a common complication of RA and can be life-threatening.
A University of Pittsburgh research team received $330K to study the effect of silver on water disinfection. The goal is to determine if silver-coated shower fixtures effectively prevent opportunistic pathogen exposure and minimize antibiotic resistance.
Researchers utilized a computational method to analyze the CDR3 regions of T-cell receptors from high-grade serous ovarian cancers. The study found that patients with low T-cell infiltration but diverse or focused repertoires had clinical outcomes similar to highly-infiltrated tumors. The authors identified the degree of divergence bet...
Researchers developed a neural network capable of recognizing retinal tissues during differentiation without modifying cells. The method allows for growing retinal tissue for developing cell replacement therapies to treat blindness and conducting research into new drugs.
Justin Metcalf, OU assistant professor, received a Young Faculty Award from DARPA to explore how the electromagnetic spectrum has become critically congested. His research aims to develop techniques for radar and communications systems to share frequency bands, enabling defense and commercial users to dynamically share unlicensed bands.
Researchers at Stony Brook University will develop simulation tools to optimize offshore wind farm layouts and reduce the levelized cost of energy by up to 15 percent using advanced turbine controls and Artificial Intelligence. The project aims to bring down the cost of developing offshore wind energy in the U.S. and support its growth.
Researchers argue that agriculture's contribution to greenhouse gas emissions is overstated and may even have a net positive effect on the climate. Per Frankelius proposes seven measures to reduce emissions while advancing sustainable agriculture.
A University of Houston study found that insufficient sleep alters children's emotional health, particularly in response to positive emotions. The research highlights the importance of assessing and prioritizing healthy sleep habits for emotionally vulnerable children.
Caterpillars of the Lycaenidae family have evolved to associate with ants, which protect them from predators in exchange for sugary secretions. These associations are driven by chemical signals and rewards, allowing caterpillars to minimize energetic costs while maximizing protection.
Researchers found a 10-μm silicate feature in large olivine particles, contradicting the Mie theory. The study's outcome sheds new light on comets and deep space, potentially affecting our understanding of cosmic dust particles.
Researchers developed engineered natural killer immune cells expressing a PD-L1 CAR that directly kill tumour cells in mice and humans. The treatment also reduces the numbers of immunosuppressive myeloid cells harbouring PD-L1.
A large population study found that the risk of cerebral palsy in IVF children has consistently declined over six time-periods, from 12.5 cases per 1000 live born in 1990-1993 to 2.8 per 1000 in 2011-2014. The prevalence dropped more significantly in singletons born from IVF compared to naturally conceived children.
A new patient-focused intervention, DISCO App, has been developed to improve patient-provider treatment cost discussions and related patient outcomes. The five-year grant-funded study will evaluate the effectiveness of the app in reducing financial toxicity among cancer patients.
A new NYU study found that exercising in nearby parks reduces anxiety and depression, but safety concerns prevent many from using them. The researchers suggest improving park lighting, programs, and community engagement to make parks feel safer.
A new study published in eLife found that early exposure to the flu virus can reduce the risk of future infections, particularly with the same subtype. The study also showed that the effectiveness of flu vaccines varies with age and birth year, suggesting that early exposure plays a role in shaping immune responses.
Researchers found that a phenomenon known as the Marangoni effect helps mezcal bubbles linger longer when alcohol content is around 50%, allowing artisans to determine perfect distillation levels. The study also reveals new fundamental details about bubble lifetimes on liquid surfaces.
Research team found that gut Piezo1 stimulates serotonin production in enterochromaffin cells, regulating gut and bone health. Serotonin is critical for gut function, emotion regulation, and blood pressure control.
Researchers developed an on-chip plasmonic spin-Hall nanograting to detect both phase and polarization singularities of incident beams. The structure directionally couples different positions depending on the polarization and topological charge of the beam, enabling rapid detection with high resolution.
Researchers from Caltech and institutions like Northwestern University used deep learning and supercomputing to identify Nyx, a product of a long-ago galaxy merger. The discovery provides the first indication that a dwarf galaxy merged with the Milky Way disk.
Researchers have overcome the limitation of super-resolution microscopy by combining dSTORM and expansion microscopy, achieving a distance error reduction to just five nanometers. This enables fluorescence imaging with molecular resolution for the first time, allowing detailed insights into molecular function and architecture.
A recent study by the Institute of Atmospheric Physics found that Beijing's air quality did not improve as expected during the COVID-19 lockdown, with secondary aerosol species showing only small changes. The research highlights a challenge for mitigating secondary air pollution in regions with high concentrations of gaseous precursors.
A new study finds that climate warming and nutrient pollution reduce the effectiveness of quagga mussels in preventing Asian carp invasion. The researchers simulated historical conditions and projected future changes, showing that Asian carp habitat improves in warmer waters, benefiting the invasive fish.
A Rutgers study found that Medicare beneficiaries' self-reported data is more accurate than administrative data sources in tracking minority populations. In 19 states, Hispanic beneficiaries were misclassified at a rate of 20%, while American and Alaskan Native beneficiaries were misclassified in over 80% of states.
A retrospective analysis of US veterans aged 75 and older found statin use associated with a 25% lower risk of death from any cause. The study also showed benefits for cardiovascular events, including heart attacks and strokes, particularly in black participants.
A prospective study of 69 couples found that female partners overestimated their IVF live birth rates by 34%, while male partners expected a 54% higher rate. The study highlights the need for clinics to set realistic expectations and provide individualized prognosis to avoid disappointment.
Two studies find that targeted taxes on sweetened beverages and strengthened nutritional standards in schools significantly reduce the purchase of these drinks among low-income children. The Healthy, Hunger-Free Kids Act also reduces childhood obesity risk among those living in poverty.
A new study published in Pediatrics found that toddlers who were obese or overweight showed signs of cardiovascular disease by age 11-12. The study, led by the Murdoch Children's Research Institute, highlighted the need for early intervention to prevent obesity-related problems with heart health.
Researchers at Los Alamos National Laboratory have developed 3D printed fractal cubes with closely spaced voids that dissipate shockwaves five times better than solid cubes. The innovative design could lead to new types of lightweight armor and structural materials effective against explosions and impacts.
Scientists at Salk Institute have identified a key gene that modifies regulatory T cells, fine-tuning the immune response. By controlling these cells, they may be able to treat both cancer and autoimmune diseases.
A new study has developed a thermoelectric device that harnesses solar energy to generate power continuously day and night, regardless of weather conditions. The device uses a wavelength-selective emitter to create a temperature difference, resulting in constant voltage generation.
A new NIH study found that infants exposed to iodine in the neonatal intensive care unit (NICU) are at higher risk for developing congenital hypothyroidism. Infants with this condition often require thyroid hormone therapy within four weeks of birth, and permanent intellectual disability may result if treatment is delayed.
Researchers found that microplastic fibers impact lobster larvae's feeding and respiration. Young lobsters accumulate fibers under their shells, while older larvae ingest particles but keep them in their digestive systems.
A new study by Beth Israel Deaconess Medical Center found that surgical delays of 30-40 days are associated with shorter survival times in patients with colon cancer. For pancreatic and gastric cancers, the results indicate that longer surgical delays may increase cancer progression and worsen patient outcomes.
Two new studies investigate COVID-19 in kidney transplant recipients, finding most don't need hospitalization, and patients on dialysis may experience different symptoms. Additionally, another study reveals distinct clinical features of dialysis patients with COVID-19, highlighting the need for more research and guidance.
Researchers discovered that human milk contains a mix of saturated and polyunsaturated fatty acids, differing from bovids and primates. The study suggests that breast milk composition is evolving to meet the growing brain's needs, with increased polyunsaturated fatty acid content in human milk.
Researchers have discovered that neurons interact differently with the same muscle partner, revealing a previously unappreciated diversity in their propensity to respond to changes. The findings suggest that these subclasses of neurons exhibit distinct types of plasticity, which is essential for learning and memory.
A study led by the University of Zurich found that 1.5 billion people will strongly depend on mountain water resources by mid-21st century, up from 7% in the 1960s. Sustainable development and climate action are crucial to ensure mountain areas continue to supply water as 'water towers'.
A new long-acting injectable form of PrEP containing cabotegravir outperformed a daily oral Truvada regimen in preventing HIV acquisition among men who have sex with men and transgender women. The study found that the injectable PrEP had a superior protective effect, with a 66% lower incidence rate compared to the daily pill.
Researchers discovered that lysosomes are active during mitosis and selectively degrade specific proteins, leading to a toroidal nucleus morphology that may indicate chromosomal instability. This finding provides a new perspective on the connection between autophagy and cell division in cancer and other diseases.
Researchers discovered that flavonoids from a specific corn line reduced inflammation in mice with an inflammatory-bowel-disease-like condition. The study suggests that flavonoid-rich corn may provide protective effects on human health, offering a promising new approach to treating chronic intestinal disease.
Physicists at MIT have designed a quantum light squeezer that reduces quantum noise in lasers by 15% at room temperature. The system uses an optical cavity with two mirrors to engineer the light exiting the cavity, allowing for more precise measurements in quantum computing and gravitational-wave detection.
A new quantum classifier introduces a tailored quantum kernel, outperforming AI technology and enhancing classification tasks with small datasets. The method exploits the quantum advantage in finding non-linear features, leading to significant improvements.
SpeechVive, a Purdue University-affiliated medical device company, has secured a convertible note to scale its business and expand access to its wearable device for treating Parkinson's disease. The funding will allow the company to pursue reimbursement from Medicare and commercial insurance companies.
Dr. Richard Plemper, a Georgia State University researcher, has received a $3.65 million grant to develop antiviral therapeutics for respiratory syncytial virus (RSV) infections. The goal is to create cost-effective and well-tolerated treatments for RSV, which affects over three million hospitalizations annually.
A Yale University study found that teens delaying driver licensure are missing critical safety training, including nighttime driving restrictions and passenger limits. This can lead to a higher risk of crashes and fatalities among vulnerable populations.
Researchers at Cold Spring Harbor Laboratory found that interfering with cholesterol storage can stop pancreatic cancer cell growth in mice and lab-grown pancreas models. The study suggests a new strategy for treating deadly disease by targeting an enzyme called SOAT1.
Researchers at Kiel University have observed rapid electronic changes in tungsten ditelluride using laser pulses, which could enable ultra-fast optoelectronic switches. The team used time-resolved photoelectron spectroscopy to visualize the changes in the material's electronic structure, revealing new insights into its unusual properties.
Researchers have successfully linked UK public health monitoring systems with the UK Biobank, enabling analysis of genetic and epidemiological factors associated with severe COVID-19. The resulting pooled data can provide near-to-real-time insights into SARS-CoV-2 spread, testing, and disease characteristics.
New research published in Developmental Cell shows that an overabundance of protein PRC1 disrupts genome errors linked to cancer. The protein acts like a viscous glue during cell division, precisely controlling the speed at which two sets of DNA are separated as a single cell divides.
Chinese researchers successfully integrated non-noble metal ions into semiconductor quantum dots, creating ultra-small nanocrystals with integrated light absorber, protecting layer and active site. The loading of metal ions enables the efficient evolution of hydrogen from water through photocatalysis.
Researchers at the University of Tsukuba found that dopamine neurons represent different parts of the decision-making process, including both evaluation and choice. The study suggests that these neurons send decision signals to other brain areas, ultimately influencing muscle action and informing choices in everyday life.
A new study found that women with higher manganese levels in early pregnancy had a lower risk of developing preeclampsia later on. The researchers analyzed data from over 1,300 women and found an association between higher manganese levels and reduced preeclampsia risk.
This study developed a hemolysis correction equation to improve serum Neuron-specific enolase (NSE) concentration accuracy in small-cell lung cancer diagnostics. The corrected results showed an increased AUC and lower cut-off value for SCLC detection, indicating the importance of hemolysis correction.
Researchers from Curtin University have found evidence that the Earth's first continents were not formed by subduction in a modern-like plate tectonics environment. The team measured iron and zinc isotopes in rocks sourced from central Siberia and South Africa, suggesting an alternative formation process.
Researchers at Trinity College Dublin have developed a novel device that enables controlled single photon emission from quantum dots, a crucial component in quantum computing and communications. This breakthrough allows for entangled states of pairs of quantum dots, paving the way for significant advancements in quantum technologies.
Researchers discovered two possible mechanisms that drive varying degrees of susceptibility and resistance to EMT, a key process in cancer metastasis and therapy resistance. The study's findings suggest that epigenetic feedback and stochastic partitioning during cell division contribute to this resistance.
Researchers at Princeton University have discovered that the source of thermodynamic instability in cesium lead iodide (CsPbI3) is the 'rattling' behavior of the inorganic cesium atom within its crystal structure. This discovery could help improve the stability and efficiency of solar cells made from this material.
A study in Peru found that shifting from subsistence farming to commercial agriculture is associated with less diverse diets and reduced access to food among local communities. The expansion of cash crops like palm oil and cocoa has led to simplified production systems and decreased agricultural biodiversity.
A University of Missouri researcher has received a $4 million grant to develop an intervention that improves reading comprehension and social studies knowledge for struggling middle school students. The five-year project will be implemented in schools across Missouri, Michigan, Massachusetts, and Washington, D.C., and aims to create be...