Researchers identify over 4,500 novel transcripts in fruit fly genome that regulate networks of genes and contribute to genetic disorders. These findings shed light on the 'dark' portion of human genome, which accounts for 98% of its content.
Monash University researchers improved aluminum alloy design by introducing specific crystal defects, enabling rapid nucleation of a strengthening phase. The study's findings have implications for lightweight alloys used in the aerospace industry.
Researchers found that propionic acid reduced relapse rates and disability progression in MS patients, with initial MRI studies suggesting reduced brain atrophy. The gut microbiome plays a crucial role in immune regulation, and altering its composition may lead to innovative dietary measures to complement existing therapies.
The study of 1,100 people with uncomplicated falciparum malaria from eight countries shows that TACTs are highly efficacious with no safety concerns. However, they showed slightly higher rates of vomiting and minor changes in the electrical activity of the heart compared to existing treatment.
The American Chemical Society is celebrating women entrepreneurs in chemistry with a special issue, featuring 20 female pioneers who have founded companies in biotechnology, solar energy, pharmaceuticals, and more. The Trailblazers issue aims to address the gender gap in funding and promote diversity in the entrepreneurial landscape.
Scientists found that crocodiles' reproductive biology and parental care may contribute to their resilience to mass extinctions. Unlike turtles, crocodiles select nesting sites carefully and bury nests for insulation, allowing them to cope with temperature fluctuations.
Researchers tested zika virus as a therapy for dogs with spontaneous brain tumors, achieving tumor reduction and longer survival. The treatment was well-tolerated and safe, with no adverse side effects.
A new study reveals that house cats have a two- to 10-time larger impact on wildlife than wild predators. The research found that most pet cats hunt in disturbed habitats and kill an average of 3.5 prey items per month, leading to an estimated ecological impact per cat of 14.2-38.9 prey ha-1 yr-1.
A KAIST research team identified a retino-cortical mapping ratio as the prime determinant in the topography of cortical organization, resolving a long-standing puzzle in understanding visual neuroscience. The study found that evolutionary variation in biological parameters induces distinct functional circuits in the visual cortex acros...
A new study by Case Western Reserve University economist Mark Votruba found that involuntary job loss leads to a dramatic increase in criminal behavior. Displaced workers experienced a 20% increase in criminal charges the year after being laid off, as well as decreased earnings and full-time opportunities.
Researchers found a toxic fungus previously thought to not be infectious in the sinus tissues of a man with refractory acute lymphocytic leukemia. The team successfully treated the infection using available antifungal drugs.
Researchers at University of Pennsylvania School of Medicine found that delivering dantrolene through the nose increases its brain concentration and duration in a mouse model of Alzheimer's disease. The study showed no obvious adverse side effects, paving the way for potential long-term treatment options.
Researchers have successfully demonstrated ionization cooling of muons, a key innovation for the development of the world's most powerful particle accelerator. The achievement marks a significant milestone in advancing our understanding of fundamental constituents of matter.
Soil microbes convert ammonium to nitrates using oxygen and diverse processes, making nutrients available to plants. The study highlights the importance of understanding microbial roles in the soil nitrogen cycle, which can inform efficient fertilizer use and mitigate greenhouse gas emissions.
A virtual reality test has shown promise in detecting balance problems in people with multiple sclerosis (MS), which can lead to falls and related injuries. The test uses a VR system to simulate falling while walking, triggering corrective reactions that can be measured as changes in gait and foot placement.
Research from Binghamton University found that older children's brains respond more strongly to rewards and less strongly to losses later in the day. This may lead to increased risk of risky behavior at night. The study suggests that understanding these differences can help prevent teenage risk-taking and psychopathology.
Researchers found that type of natural organic matter affects rate and level of arsenic release from sediments. Arsenic contamination in water can cause health issues like poisoning, cardiovascular disease, and cancer.
A new study reveals that conserving natural habitat around strawberry fields can decrease crop damage costs by up to 23% and increase yields, without compromising food safety. Removing natural habitat, on the other hand, can lead to significant cost increases of up to 76%.
A new study reveals that clearing acacia-dominated bushland for farming can raise land surface temperatures by up to 1.8°C, comparable to forest clearing. The findings suggest that preserving these ecosystems could mitigate climate change in the region.
Researchers have discovered a potential new treatment for drug-resistant epilepsy using compounds derived from magnolia trees. The study found that extracts from the bark of Magnolia officinalis reduced seizure-like behavior in both zebrafish and mice, providing a promising lead for the development of new treatments.
Researchers used existing data from known coronaviruses to predict which parts of SARS-CoV-2 are capable of activating the human immune system. The study identified five regions in the spike glycoprotein, membrane protein, and nucleoprotein that elicit a strong immune response.
Researchers argue that AI can facilitate human interactions in family medicine, making patient care more meaningful. By incorporating informatics into primary care specialties, AI can help reduce administrative burdens and improve population health.
A Simon Fraser University-led study predicts that climate-driven glacier retreat will challenge some salmon populations, while creating new habitats in others. As glaciers lose up to 80% of their ice volume by 2100, southern watersheds may face low water flows and warmer temperatures, posing challenges for adult and young salmon.
A new study has validated a better way to stratify BPD risk in extremely preterm infants, using a longer duration of supplemental oxygen. The findings suggest that babies who require oxygen for over 120 days are at high risk of respiratory complications and should receive expanded ventilation before discharge.
Researchers have developed a novel approach for quantum error correction that can mitigate certain types of random fluctuations, enabling the creation of more efficient quantum computers and sensors. By targeting specific noise sources, this method could significantly improve the performance of quantum systems.
Researchers at Louisiana State University have discovered a new species of shrew, the Sulawesi hairy-tailed shrew, which has thick hair on its tail and climbs trees. The discovery highlights the significant diversity of mammals in Indonesian islands, with many habitats remaining unexplored.
A Rutgers-led study found that climate change could threaten the survival and development of common whelk in the mid-Atlantic region. The species' spawning cycle is closely linked to temperature, which is expected to increase due to rising temperatures.
Scientists used gas chromatography and sensory panel analysis to uncover volatile compounds in aged cognac, finding terpenoids for the first time. The study reveals how specific compounds enhance or suppress flavors, shedding light on aging's impact on aromas.
A new study found significantly higher mortality rates, hospitalization rates, and deaths after hospitalization among low-income older adults dually enrolled in Medicare and Medicaid compared to those solely enrolled in Medicare. The study suggests that health inequities persist despite efforts to improve healthcare access.
Scientists at Chiba University have discovered a previously overlooked electronic transition 'S0 → Tn' in heavy-atom-containing molecules exposed to visible light. The study reveals that this mechanism promotes radical reactions in photoreactions with visible light, which was not previously considered a main role.
Researchers found over 50 dinosaur footprints on ancient coastal mudflats, including stegosaurian and theropod dinosaurs. The discovery expands the list of known dinosaurs living in the region during the Middle Jurassic Period.
A new collaborative research center will focus on developing energy-efficient technologies for water desalination, purification, and reuse. The center aims to reduce energy needed for desalination, improve water recovery, and support safe water reuse.
A collaborative research team from Dartmouth and Honduras found a high level of participation in rural cancer screening events, resulting in over 88% of identified individuals seeking follow-up care. The 'multiphasic' approach involved multiple cancer screenings in one event, which was well-received by local communities.
Environmental engineers at San Diego State University have developed a rapid detection system for bacterial contamination in water, which can alert authorities to pollution in real-time. The system uses tryptophan as a marker and has been tested in Alvarado Creek, where it correctly identified sewage leaks and spills.
Researchers successfully measured and controlled the length of the Kondo cloud, a phenomenon discovered in the 1930s that explains resistance increase in certain metals. The findings provide insights into multiple impurity systems, including high-temperature superconductors.
Researchers at Boston Children's Hospital have discovered a new approach to cancer immunotherapy by reactivating the gasdermin E gene, which can convert 'cold' tumors into 'hot' ones that the immune system can target. The team showed that re-introducing gasdermin E in mouse models triggered pyroptosis and suppressed tumor growth in var...
A UK study found that cyclists have a 45% higher risk of hospital admission for a first injury compared to car commuters, but lower risks of cancer, cardiovascular disease and death. Cycling also offers health benefits such as improved fitness and lower body fat.
A new study measures the intensity of past methane release using sulfur isotopes in foraminifera shells, providing a novel tool for reconstructing geological records. The analysis reveals strong methane fluctuation responses to global warmings and hydrate dissociation.
Researchers at Rice University found that Buffalo Bayou's natural form is better at absorbing floodwater and preventing it from spilling over into heavily populated areas. The study shows that urban development in the Brays watershed increased the 100-year flood plain, making it more prone to flooding.
The ESO's Very Large Telescope has observed an ultra-hot giant exoplanet where it rains iron on its night side. Strong winds carry iron vapour from the day side to the cooler night side, where temperatures decrease, resulting in a unique and extreme phenomenon.
Research at Instituto Gulbenkian de Ciência uncovered two new mechanisms in the microbiota's evolution, driven by aging and nutrient competition. In mice, E. coli adapts to inflammation and scarce nutrients in older individuals, leading to potentially pathogenic changes.
Research finds that the dorsal attention network (DAT) and default-mode network (DMN) are anti-correlated, with suppressed activity during unconscious states. The study uses fMRI data to uncover temporal circuits of brain activity supporting human consciousness.
A randomized controlled trial found that tailored messages addressing HPV vaccine concerns improved intent to vaccinate, while a bundled approach was less effective. The study suggests that personalized messaging may be essential for increasing HPV vaccination uptake among hesitant parents.
Researchers at the University of Illinois have developed a method to precisely control the sequence in synthetic polymers, allowing them to study charge transport properties and measure conductance through single chains. This work has significant implications for designing and manipulating materials with designer properties.
A new wireless, battery-charged monitoring system is being tested to provide clinical-grade care for premature babies and pregnant women in low-resource settings. The soft, flexible sensors offer advanced features such as crying and movement detection, allowing for early intervention and improved health outcomes.
Researchers at Rice University have developed a new strategy to destroy antibiotic-resistant genes, known as superbugs, in sewage system wastewater. The nano technology traps and degrades these genetic remnants before they can infect other bacteria.
A doctors' group is suing California for neglecting to add processed meat, such as hot dogs and bacon, to the state's cancer-causing substances list under Proposition 65. This move comes after experts classified consumption of processed meat as carcinogenic to humans, increasing risks of colorectal, breast, prostate, pancreatic, and ov...
The new guidelines establish evidence-based limits for exposure to high-frequency electromagnetic fields, setting thresholds below which no adverse effects can occur. The report provides guidance on basic restrictions and reference levels to ensure safe exposure in various settings, including occupational environments.
A study found that accounting for local perspectives when designing conservation policies may increase community support and improve their success. Local people's frustrations with policies were rooted in technical issues, lack of funding, and inadequate involvement in decision-making.
A new guide seeks to provide healthcare providers with useful tools and information to support new mothers with the challenges of exclusive breastfeeding during the first six months. The guide addresses gaps in knowledge and support created in previous decades, providing evidence-based solutions for breastfeeding management.
A study published in Neurology found that 82% of people with Parkinson's reported one or more eye problems, compared to 48% without the disease. Eye problems often interfered with daily life for 68% of those with Parkinson's, affecting activities like driving and reading.
New research suggests that scientists who are known for their hard work, like Thomas Edison, are more motivating than those who are viewed as naturally brilliant, like Albert Einstein. The findings dispel myths about what it takes to succeed in science and can help optimize science education.
Professor Peter Girguis has been awarded a five-year grant from the Gordon and Betty Moore Foundation to pursue innovative research on symbiosis in aquatic systems. His team will use engineering approaches, genome sequencing, and protein analysis to understand how these symbioses change their environments.
A recent survey found that people are more willing to donate genomic data if they have control over its use and can be compensated for their involvement. The study, which involved 2,020 survey respondents, also revealed that nearly half of participants would only provide their data in exchange for payment.
A University of Colorado Cancer Center study found that African American patients were half as likely as non-Hispanic whites to receive PET-CT imaging for non-small cell lung cancer, while Hispanics received it 70% as frequently. This disparity may be due to limited access to specialized imaging equipment and unconscious bias.
Researchers found a method to promote cancer cell growth using silica-coated gold nanorods exposed to near infrared light, with a 36.13% higher growth rate than normal incubator conditions. The heat shock proteins induced by the nano heat islands helped protein folding and cell survival.
Researchers detected chemical variations between day and night on the planet, revealing the presence of iron vapour condensing into drops on the dark side. This discovery provides insights into the extreme climate conditions on ultra-hot giant exoplanets.
Researchers from the University of Illinois have developed a system called VoLoc that uses microphone array recordings and room echoes to infer user location within a home. This technology can improve smart devices' support for available skills, such as turn-on-light or increase-temperature commands.
Researchers at the University of Helsinki discovered novel loci associated with hip dysplasia and osteoarthritis in German Shepherds, highlighting the hereditary nature and polygenic background of the disorder. The study sheds light on the genetic factors influencing complex diseases and may lead to better treatment options in the future.
Researchers discovered a 'mild depolarization' of the inner mitochondrial membrane regulates mROS production and is key to the anti-ageing program. This mechanism falls apart in mice at 1 year but persists in naked mole rats up to 20 years, contributing to their exceptional longevity.