As consumers become richer, they spend more on services like health and education, while spending less on agriculture and manufactured goods. The study reveals that income and preferences play a larger role than productivity in shaping the sectoral composition of the economy.
Researchers found that ibuprofen inhibits the alternative splicing event generating RAC1B, overexpressed in BRAF-mutated colorectal tumors. Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein kinase complex, promoting nuclear exclusion of SRPK1 and SRSF1.
Researchers successfully transformed oral epithelial cell rests of Malassez into progenitor stem-like cells, which were then directly differentiated into endothelial, mesenchymal stem, and osteogenic cells. This breakthrough could lead to the development of new periodontal regenerative therapies.
A new technique for sampling and testing cells from Barrett's esophagus patients can detect specific chromosomal alterations, including the presence of esophageal adenocarcinoma. The approach combines esophageal brushing with massively parallel sequencing to provide an accurate assessment of disease stages and identify high-risk patients.
Researchers at Greenwood Genetic Center have identified cholesterol accumulation as a key contributor to the symptoms of genetic movement disorders, including seizures and balance issues. The study provides new hope for treatments targeting cholesterol accumulation, such as the drug 2-hydroxypropyl-beta-cyclodextrin, which showed signi...
Researchers at Duke University Medical Center identified a key reason hormone therapies fail and proposed a new treatment strategy directly targeting the cancer's fuel source, glutamine. By inhibiting glutamine utilization, tumor growth is successfully inhibited in studies using prostate cancer cell lines and animal models.
Researchers have developed a method to create arbitrary dimensional quantum-like classical light directly from a laser, enabling the control of high-dimensional classically entangled states. This breakthrough opens up new possibilities for applications in quantum metrology, error correction, and optical communication.
Farmers prioritize government and agricultural sector information, while scientists value scientific information. Female farmers and those using organic farming methods rate biodiversity as more important than others. The study highlights knowledge gaps between research, agriculture, and policy practice.
Scientists at MLU and IPB improve CRISPR/Cas9 to simultaneously knockout multiple genes in plants, overcoming previous limitations and enabling complex trait investigations. This approach allows for the study of gene interactions and redundancies, paving the way for more efficient research methods.
Prof. Zeleny proposes new systems, such as Integrated Productive Environments (IPE), to help human systems evolve and thrive in a rapidly changing world. He emphasizes the need for competent cooperation, multidisciplinary education, and adaptable management strategies to overcome the challenges of disequilibrium.
A new study suggests that increasing primary care physicians by one per 1,500 residents in critical-shortage regions could boost life expectancy by an average of 56 days and prevent over 7,000 deaths annually. This analysis is based on data from 3,400 regions, highlighting the need to incentivize doctors to practice in underserved areas.
Researchers at Northwestern University have developed a new method for producing propylene, a key component of plastics, that uses less energy. The technique, which involves the use of two catalysts, produces yields up to 30% higher than traditional methods, making it a promising solution for more energy-efficient plastics production.
A new toolkit developed by researchers at the University of Houston, in collaboration with the National Institutes of Health, enables rapid drug development for brain diseases and injuries. The toolkit uses high-resolution imaging to analyze unhealthy brain tissue, revealing multiple biological processes at once.
Lithium-metal batteries, used in next-gen electronics and electric vehicles, suffer from calendar aging, losing charge even when turned off. The nature of the battery electrolyte significantly impacts aging, with different electrolytes causing varying levels of corrosion and efficiency loss.
Researchers developed a standardized drying protocol for goldenseal to preserve its medicinal properties. The study found that high temperatures decreased the levels of canadine, while berberine and hydrastine remained unaffected. This optimized drying process could lead to more predictable health outcomes and applications.
Researchers at the University of Florida have discovered a way to evaluate enzyme lifespan, allowing them to identify enzymes that need improvement. This breakthrough could lead to increased crop yields by reducing energy spent on replacing worn-out enzymes.
A research team developed a straightforward method to find high-Q modes in single dielectric nanocavities. They discovered high-Q modes using Mie mode engineering and avoided crossing, resulting in improved photonic device performance and applications.
A study by the University of Florida found that male patients with a single general physician were more likely to receive a prostate cancer screening test during a period when it was not recommended. The trust between doctor and patient is strong, but physicians must practice evidence-based care.
Scientists have discovered over a dozen gene variants causing the rare eye disease MacTel, which leads to progressive retinal degeneration. The study identifies PHGDH as a key enzyme essential for serine production, whose partial loss contributes to MacTel's development.
The use of dental implants for tooth replacement requires careful consideration of biomaterials, which must integrate into the body while minimizing negative immune responses. Researchers have compared titanium and zirconia, highlighting the importance of surface modification processes and coatings in optimizing implant performance.
Researchers used layered double hydroxide (LDH) to inhibit inflammatory environments surrounding spinal cord injuries, accelerating neuron regeneration and neural circuit reconstruction in mice. LDH promotes the activation of channels for neuron excitation and induction of action potential, improving locomotive behavior.
Researchers discovered a powerful approach for treating diabetic foot ulcers by targeting a gene that controls tissue growth and regeneration. The new treatment has shown promising results in animal models and human skin equivalents, and may hold potential for repairing internal organs.
Researchers found that considering soil organic matter improves water retention, mitigating crop yield losses from drought. Including this data in insurance premiums could reduce liabilities by 36% while increasing corn yields by 35 bushels per acre.
Researchers at Linköping University have developed nanoporous cubic silicon carbide that efficiently traps and harvests sunlight to split water into hydrogen gas. The material's high charge-separation efficiency boosts water splitting efficiency, making it a promising approach for producing renewable energy.
A new report by Harvard Medical School researchers found that TB diagnoses in the US are often delayed, leading to a higher likelihood of infection transmission and disease progression. The study suggests that increased clinician awareness and education can help minimize these delays.
Christopher Musco, an assistant professor at NYU Tandon, received a $562,224 NSF grant to develop new algorithms for processing massive data sets. His project aims to democratize big-data modeling and advance US mathematics education through closer ties with STEM fields.
Urban populations across Africa are forecasted to triple by 2050, resulting in significant environmental changes. Including local community voices in early planning stages can help reduce the impact of climate-related events and promote more inclusive urban climate policies.
A study of over 11,000 participants found that certain metabolic processes are associated with up to 14 diseases. The researchers identified key factors influencing human metabolism and developed a web application to make their results publicly available.
A recent study by University of California San Diego researchers identified 12 essential attributes that explain why commercial carbon capture and sequestration projects succeed or fail in the US. The credibility of revenues and incentives is crucial, with policies like the 45Q tax credit providing a guaranteed revenue stream.
Children's Hospital Colorado and STAQ Pharma developed pre-filled sterile injectables for pediatric patients, addressing drug shortages and medical waste. The partnership optimizes patient care by providing individualized medication concentrations and doses.
An international study found that insomnia, disrupted sleep, and daily burnout are linked to a heightened risk of not only becoming infected with coronavirus but also having more severe disease and a longer recovery period. The study also revealed that every extra hour of sleep at night was associated with 12% lower odds of infection.
The summit, to be held April 26-28, will bring together Nobel laureates and leaders to explore actions to achieve a more sustainable future. The event aims to mobilize action on issues like climate change, biodiversity loss, inequality, and technological advancements.
Iron, a micronutrient crucial for phytoplankton, is being released from deep ocean sediments, providing a new source of nutrition for drifting marine organisms. This finding challenges previous expectations and has significant implications for studying the ocean carbon cycle and managing the marine environment.
A recent study published in eLife reveals that astrocytes, a type of glial cell, can independently promote longer or deeper sleep in mice by manipulating slow-wave activity. The findings suggest that targeting astrocytes could lead to new insights into sleep disorders and brain diseases linked to sleep disturbances.
Researchers found that PAHs toxins degrade in sunlight into smaller 'children' compounds that are often more toxic than the original 'parent' PAHs. These compounds can accumulate in rivers, dams, and agricultural land, posing significant environmental challenges.
A study investigated incidental findings in brain MRIs of children, revealing significant rates that could affect diagnoses and treatments. The research highlights the importance of thorough image review and reporting.
The TB burden in Europe is decreasing, with a 19% overall decline from 2015-2019. However, drug resistance remains a major concern, and the COVID-19 pandemic may stall or cause setbacks in the fight against TB. Treatment outcomes are suboptimal, with only 77% of patients successfully completing treatment in 2019.
A University of New Mexico study analyzed data from four US cities and found that as vaccination rates increase, it becomes economically advantageous to relax social distancing measures and open businesses. The study suggests a gradual relaxation of restrictions can minimize economic costs while reducing public health risks.
A recent study published in JAMA Network Open found that the quantity and quality of SARS-CoV-2 antibodies differ significantly among children, adolescents, and young adults. The research has important implications for understanding the immune response to COVID-19 vaccines and informing public health strategies.
A new protein purification process, known as precipitation, could significantly reduce the cost of producing antibodies for chronic diseases and COVID-19 treatment. The method eliminates the need for costly chromatography processes, making it a promising solution to drive down production costs.
Researchers found that people with schizophrenia, bipolar disorder, or major depression are more likely to die within 30 days and one year after a heart attack. The study highlights chronic health inequalities faced by those with serious mental illness and calls for urgent action to address disparities.
Researchers at Harvard's Wyss Institute develop programmable DNA self-assembly strategy for ultrasensitive diagnostic biomarker detection and scalable fabrication of micrometer-sized structures. The 'crisscross polymerization' approach enables robust nucleation control and growth to large sizes.
A team of researchers led by Professor Alexander Meyer has created an early warning system for intensive care units (ICUs) using big data and artificial intelligence. The system predicts postoperative bleeding and acute kidney injury with high accuracy, allowing timely interventions to save lives.
A UC Riverside study analyzed fourth-generation electronic cigarette pod atomizer design features, identifying toxic elements such as nickel, chromium, and iron. The findings suggest that these elements may accumulate in the environment and contribute to chemical pollution, highlighting the need for further research on e-cigarette safety.
A consortium of researchers found that some days saw up to 3-4 new cyber-attacks during the pandemic, with most involving phishing and malware. The study reveals an explicit connection between governmental policy announcements and cyber-crime campaigns.
The AstraZeneca vaccine demonstrated high vaccine efficacy of 78.9% against symptomatic COVID-19 disease, including severe disease or hospitalization. The vaccine also showed no increased risk of thrombotic events or cerebral venous sinus thrombosis among vaccinated participants.
A significant number of older adults in the US lack necessary equipment to assist with bathing and toileting. The study estimates that many adults struggle without this support, highlighting a pressing public health concern.
A novel culture-free self-driving DNA nanosensor can accurately detect lethal superbugs like MRSA with high sensitivity, enabling rapid and precise sensing of a microorganism's DNA. The detection time is reduced to just 10 seconds, making it a cost-effective tool for timely diagnosis and treatment.
A study at the University of Helsinki uses machine learning to analyze bone marrow samples and identify genetic mutations associated with myelodysplastic syndrome (MDS). The technique provides new insights into disease progression and can help assess and diagnose hematological malignancies.
A large study of 11,679 nine- and ten-year-old children found potentially life-threatening brain abnormalities in 1 in 500 children and minor abnormalities in 1 out of 25. The study aims to save lives by reviewing MRI scans for incidental findings.
The Global Harmonization Initiative aims to establish a legislative framework for recognized food safety professionals, promoting formal requirements for education, registration, and professional bodies. This move seeks to enhance food safety practices globally by setting standards for roles in managing food safety.
Children who attended a comprehensive preschool program had lower body mass indexes and reduced obesity rates compared to those who did not attend the program. The study found that women participants were particularly less likely to be obese.
A team of researchers developed an ultrasmall needle-electrode technology called 'STACK' that enables high-quality brain recordings in mice with a high signal-to-noise ratio. The device offers improved biocompatibility and minimized tissue damage, making it suitable for long-term and safe chronic recordings.
Researchers have developed a new catalyst for the low-temperature hydrogenation of CO2 to methanol with high activity and selectivity. The sulfur vacancy-rich few-layered MoS2 catalyst achieves 94.3% methanol selectivity at 180°C, outperforming commercial catalysts.
A recent study reveals a 97% decline in lithium-ion battery costs over the last three decades, driven by rapid growth of electric vehicles and renewable energy. This rate of improvement is comparable to that of solar photovoltaic panels.
Researchers at the University of Seville are studying the Type VI Secretion System (T6SS) in bacteria like Pseudomonas putida to develop biocontrol agents for sustainable agriculture. The T6SS is a molecular weapon that allows bacteria to quickly eliminate competitors and protect plants from diseases.
Researchers found that chronic inflammation in osteoarthritis triggers a harmful 'feed-forward' loop in cartilage cells, making them more sensitive to pressure and leading to further breakdown of the cartilage. This discovery opens the door for disease-modifying treatments for osteoarthritis.
A Skoltech researcher has discovered a new model of quantum computation, the variational model, which enables universal computation using limited control over a quantum simulator. This breakthrough bridges the gap between traditional quantum simulators and quantum computers.
The new battery has an energy density of 24 Wh/kg, ten times higher than previous prototypes, and a stiffness of 25 GPa. This breakthrough paves the way for 'massless' energy storage in vehicles and consumer electronics.
A team led by Michigan State University's Pang-Ning Tan is working to make artificial intelligence algorithms more fair and aware of their potential biases. They're developing a definition of fairness that considers perspectives from groups of people, rather than just individual outcomes.