A team of scientists has identified a compound that shows promise in easing COVID-19 symptoms by targeting the cellular quality-control system damaged by coronaviruses. The compound, AMG PERK 44, was found to halt virus replication and boost lung function in mice infected with MERS.
Researchers found that changes in eDNA concentration accurately reflect movement of creatures between the twilight zone and surface. The study provides clues about species diversity, distribution, and migration patterns using genetic material shed by marine creatures.
A study published in Nature Communications reveals that the transcription factor Sp7 and its target gene osteocrin play a crucial role in osteocyte dendrite formation. Deletion of Sp7 causes severe defects in dendrites, but activating osteocrin can reverse these defects in mice.
Researchers aim to provide digital histopathology images and quantitative information without invasive biopsies, addressing a common challenge in wound healing. The project combines metabolic imaging, deep learning techniques, and collaboration with experts in the field.
A team of researchers identified the ultrafast carrier dynamics in monolayer MoS2/ReSe2 heterostructures, revealing relaxation pathways and intermediate processes. The study provides comprehensive insight into photocarrier dynamics across charge separation, enabling the development of optoelectronic devices.
Staffordshire University researchers investigate the impact of melting snow and ice on ski tourism. Despite environmental changes, tourists prioritize mountains, scenery, and hiking opportunities, highlighting the need for adaptation and diversification in the industry.
The AP-PLAT website provides online tools such as ClimoCast, Climate Impact Viewer, and ClimoKit for climate projections, impact assessments, and capacity development. The platform aims to support regional climate change adaptation efforts in the Asia-Pacific region.
Researchers found an association between prenatal PFAS exposure and late-onset preeclampsia, suggesting toxic effects outside placental development. The study analyzed data from pregnant women at Brigham and Women's Hospital, revealing a correlation between PFAS chemicals and the condition.
Researchers found that roads can be deadly for species survival, with certain traits like early age of sexual maturity helping some species bounce back from roadkill deaths. However, others like brown and black bears are particularly vulnerable due to late maturity age and small litters.
Male smokers have a lower rate of blood pressure control than female smokers, according to a study by the American College of Cardiology. Smoking cessation is key to improving health outcomes, with studies showing that quitting smoking can lead to better adherence to treatment and improved cardiovascular care.
The PRACE COVID-19 Fast Track Call allocated thousands of years of computer simulations to help fight COVID-19, yielding key lessons for the scientific community. Researchers across Europe used over half a billion core hours of HPC resources to tackle various aspects of the pandemic.
Researchers from TGen matched the exact strain of coronavirus shared among a Phoenix-area owner, his cat and his dog, marking the first reported US transmission of COVID-19 from a pet to pets. The study found that the virus spread from the pet parent to either the dog or cat, or both.
A new study reveals that many cratons were uninhabitable for microbes for much of their existence, with the longest period of habitability not much beyond a billion years. The deep biosphere, home to microbial life, has evolved over geologic history, and modern microbes are related to ancient ancestors in the subsurface.
A new study suggests that women are just as competitive as men in competitions, and that their reluctance to take risks is not the cause of the gender wage gap. Researchers found that when given the option to share winnings with losers, women were more likely to compete and excel.
Researchers discovered that a heat-soluble protein from tardigrade cytosols self-assembles into fibrous condensates under desiccation conditions. This dynamic organization suggests multistep anhydrobiotic mechanisms, allowing organisms to survive without water.
Researchers have developed a superconducting silicon-photonic chip for quantum communication, enabling optimal Bell-state measurement of time-bin encoded qubits. This breakthrough enhances the key rate of secure quantum communication and removes detector side-channel attacks, significantly increasing security.
Researchers at Shinshu University discovered a new type of amyloidosis associated with duodenal neuroendocrine tumors that produce somatostatin. Laser microdissection and liquid chromatography-tandem mass spectrometry techniques were used to identify the amyloid formation.
A 1.5°C temperature increase affects algae and animal species living on UK coastlines, with significant changes in species abundance and breeding patterns. The study highlights the importance of considering local temperature variations when predicting climate change impacts.
A team of Lehigh University undergraduates has won the National Institutes of Health's Healthcare Technologies for Low-Resource Settings Prize for developing a diagnostic device to detect sickle cell disease in infants. The $15,000 prize will support further development and testing of the device, which could improve healthcare outcomes...
Researchers developed a viral panel that enables simultaneous testing for SARS-CoV-2 and common respiratory viruses, providing insight into coinfections and viral spread. The tool helps predict and mitigate future outbreaks by tracking novel viral variants and their patterns of spread.
A study of over 2000 participants found that time spent alone during the pandemic led to improved well-being scores, with 43% describing activities as a source of competence. Adults experienced disrupted well-being and negative mood less frequently than teenagers, highlighting the importance of solitude for mental health.
A quantum search algorithm, known as Grover Adaptive Search (GAS), has been demonstrated to solve the index selection problem in index modulation faster than a classical computer. This breakthrough could lead to significant energy efficiency gains for wireless networks.
Researchers sequenced DNA from 242 accessions of Aegilops tauschii, a wild relative of bread wheat, and discovered a distinct lineage that contributed to the modern wheat genome. This ancient contribution has provided valuable genetic diversity for improving disease resistance, yield, and environmental resilience in modern wheat.
A lung model mimicking complex anatomy has enabled the assessment of respiratory volumes using a gas-in-scattering-media absorption spectroscopy (GASMAS) technique. The study demonstrates the feasibility of GASMAS to sense changes in gas volume in a controlled environment, paving the way for potential clinical applications.
David Wong's project aims to comprehensively measure family and social support in US counties by including demographic variables like age, ethnicity, and spatial dimensions. The research will provide more accurate health rankings and inform policy decisions.
A large national sample of US adolescents showed an increase in average total daily screen time from 3.8 hours/day pre-pandemic to 7.7 hours/day early in the pandemic period.