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Science News for October 24, 2021


Role of TGF-β/SOX9 axis in carcinogenesis using 3-dimensional in vitro and in vivo models

A study investigates the role of the TGF-β/SOX9 axis in promoting cancer migration and invasion in oral squamous cell carcinoma. The research found that CAF-induced TGF-β1 upregulates SOX9 expression, leading to increased cancer invasiveness and poor prognosis. The findings suggest a potential therapeutic target for developing novel tr...

SourceNiigata University·JournalTranslational Oncology·DateOct 24, 2021

A new approach to treating leukemia

Researchers at Bar-Ilan University have developed a novel treatment method that destroys cancer cells by targeting the cytoskeletal protein WASp, which is unique in active hematologic cancer cells. The approach uses small molecule compounds identified through AI and machine learning to inhibit proliferation and destroy malignant cells.

SourceBar-Ilan University·JournalNature Communications·DateOct 24, 2021