A team of researchers from INRS has developed a new tool to measure the effects of endocrine disruptors in wastewater. Using human cell lines, they can detect the presence of these contaminants and predict their harmful effects without resorting to animal testing.
Researchers found that adolescents who consumed ultra-processed foods were more likely to be obese, having abdominal and visceral obesity. The study used data from 3,587 US adolescents aged 12-19, dividing them into three groups based on the amount of ultra-processed foods in their diets.
Researchers at Northwestern University have developed a stable and selective catalyst for breaking down polyester-based plastics into their component parts. The method uses metal-organic frameworks (MOFs) and requires only three components: plastic, hydrogen, and the catalyst.
Researchers at Tohoku University and UCLA have made a breakthrough in high-voltage metal-free lithium-ion batteries using a small organic molecule, croconic acid. The battery has a strong working voltage of around 4V and a high theoretical capacity, potentially leading to more energy-dense and cost-effective batteries.
Scientists have developed a novel approach to targeting transcription factors, which could lead to new therapies for cancer and other diseases. A peptide designed to target the Mediator complex has been shown to selectively inhibit p53, a critical gene in human development and stress response.
A new study has shown that increasing genetic diversity can improve researchers' ability to identify important genetic markers for health conditions. The study, which analyzed data from over 470,000 Hispanic/Latino individuals, identified 42 previously unidentified regions of the human genome related to BMI, height, and waist-to-hip ra...
Researchers developed an alkali-resistant pervaporation membrane with excellent performance in separating sodium chloride solutions. The composite membrane showed stable desalination and alkaline resistance, making it suitable for various industrial applications such as papermaking and water resource recovery.
A team of scientists has successfully implemented a novel QSDC system that transmits information directly using quantum states over 100 km of fiber, achieving ultra-low error rates and high transmission rates. The system uses photonic time-bin and phase states, resulting in a record-breaking distance of 100 km.
The partnership between pharma companies and patient influencers has raised concerns about the potential risks and benefits. While some see it as a way to improve disease awareness and treatment options, others worry about misinformation and advertising blurring the lines between opinion and ad content.
A study found that over a third of cancer patients in the UK were diagnosed through emergency routes, with older and advanced cancer patients being disproportionately affected. The researchers called for better symptom awareness, reduced barriers to screening, and additional diagnostic capacity to improve early diagnosis.
This analysis examines the association between COVID-19 vaccination prioritization policies and incarcerated individual vaccination rates. The study found that policies favoring certain groups led to significantly lower vaccination rates among incarcerated populations.
A new paper by an Oregon State University-led research team provides a scientific framework to shape the rollout of a program in Oregon allowing the use of psilocybin for therapeutic reasons. The research highlights the importance of Indigenous traditions and safety guidelines for using psilocybin-containing fungi.
Extracellular vesicles play a crucial role in the aggregation and deposition of TTR amyloids in hereditary transthyretin amyloidosis, according to new research. The study reveals that EVs promote the formation of V30M-TTR aggregates on cells, leading to tissue damage.
A postmortem examination of 23 COVID-19 patients revealed significant changes in the sensory system responsible for processing smells. Loss of smell is an early symptom of COVID-19, and this study provides new insights into its underlying causes.
A study by Tokyo University of Science researchers used WCNs with increasing n values to find features of language that cannot be analyzed using existing WCNs. They found important features in networks with more than three co-occurrences, independent of text data.
Researchers developed a new way to help protect the natural flora of the human digestive tract by engineering bacteria to break down beta-lactam antibiotics. This approach protects the microbiota in the gut while allowing antibiotics to remain effective, reducing the risk of infection and antibiotic resistance.
Researchers have made a breakthrough in controlling bacterial nitrogen fixation by cereals, enabling them to produce their own ammonia fertiliser. This development has the potential to reduce reliance on industrially produced ammonia-based fertilisers and mitigate environmental pollution and greenhouse gas emissions.
Researchers are developing technologies to image tens or hundreds of human brains at unprecedented speed, generating comprehensive brain-cell atlases to uncover behavior, emotion, and cognition. The team aims to chart the diversity of brain cells, including neurons and glial cells, to gain insights into normal brain function and disease.
Adding immunotherapy to chemotherapy before surgery reduced the risk of recurrence and death in lung cancer patients by 37%, according to a phase III trial. The treatment also led to a nearly twelvefold increase in pathological complete response, with 24% of patients achieving no active cancer remaining when the tumor was removed.
Researchers at UCF create brain-like devices that enable AI to function independently, allowing technology like robots and voice assistants to operate in remote areas or space. The devices use parallelism and in-memory computing, similar to the brain, for AI and unsupervised learning.
Researchers used vertical sounding data to improve forecasting of Zonda windstorms, a severe weather phenomenon affecting Argentina's agricultural communities. By analyzing atmospheric profiles and applying principal component analysis, they achieved reliable forecasts with up to 24 hours of lead time.
A study published in the Ochsner Journal found that 28.2% of current smokers reported increased tobacco use during the pandemic, while former smokers experienced no relapse. Researchers identified correlates of increased tobacco use, including mental health concerns and coping strategies.
Patients in low-socioeconomic-status neighborhoods and those needing language interpretation had higher connection rates for successful video visits, thanks to medical assistant involvement. Overall, the study found 87% of video visits had a successful connection.
A new study by NYU researchers found that SNAP-eligible families are less likely to purchase healthy foods like fruits, vegetables, and meat when buying groceries online. Participants cited concerns over the quality of products selected by hired shoppers as a major factor.
The RACE Act has led to an increase in required studies for cancer drugs targeting molecular targets relevant to pediatric cancer. Since its implementation, 42.9% of approved drugs have been required to conduct pediatric studies, up from 8.3% before the act.
A new study by USC researchers uses focused ultrasound technology to stimulate the retina of blind rats, demonstrating the potential for a non-surgical solution to restore sight. The technology generates sound waves that activate neurons and send signals to the brain, bypassing traditional light-based stimulation.
A new study published in Ecotoxicology and Environmental Safety reveals that microplastics in the Cauvery River may be causing growth defects in fish, including skeletal deformities and DNA damage. The study found that pollutants from slow-flowing and stagnant sites caused significant harm to zebrafish embryos.
Researchers have developed a new 3D printing technique to fabricate microfluidic devices with precise channels at the microscale. This breakthrough allows for accurate creation of channels in clear resin, enabling applications such as COVID-19 detection and cancer research.
A recent study by researchers from the University of Cambridge and Boston University has made a major breakthrough in understanding how cuckoo finches mimic eggs of multiple host species. The team found that female cuckoo finches inherit their egg-mimicry abilities from their mothers, allowing them to exploit different host species. Ho...
Yale scientists have discovered a protein called augmentor-alpha that regulates body weight in mice, offering insights into potential new treatments for metabolic disorders. The protein is found in the hypothalamus region of the brain and plays a role in energy conservation during fasting.
Researchers identified genes and epigenomic marks that enable cancer cells to resist chemotherapy. By inhibiting these marks, epi-drugs can restore treatment sensitivity. Future clinical trials aim to adapt this concept for human use.
A new review found that Autistic women face significant challenges in breastfeeding, despite being motivated to do so. The lack of understanding of their needs and limited support from healthcare professionals exacerbate these issues.
Research reveals that climate change and drought can cause significant yield losses in soybeans, even with high levels of weed control. To mitigate this, farmers need to adopt integrated weed management strategies, including the use of soil-residual herbicides and late-maturing soybean varieties.
Researchers at University Hospitals and Case Western Reserve University have discovered a new receptor, Ptprd, that controls appetite and body weight. The receptor trap drug suppresses appetite, body weight, and blood glucose levels in obese mice.
A study revealed a negative correlation between living in areas with low residential greenspace and lower depressive symptoms among people with spinal cord injury. The findings have implications for urban planning and public policy, highlighting the need to understand how community environment factors influence quality of life.
Current drug optimization prioritizes potency/specificity over tissue exposure/selectivity, leading to clinical failures. A new approach, STAR, classifies drugs based on potency/selectivity, tissue exposure/selectivity, and required dose to achieve clinical efficacy/toxicity balance.
A kindness training program adapted from Children's Kindness Network improves both parents' resilience and children's empathy. The study found that teaching kindness at home boosts parental resilience and enhances emotional intelligence in preschoolers, supporting overall brain health.
Researchers have discovered that rhesus monkeys can sense their heartbeats, which may help understand interoception and its link to mental health conditions. This finding provides an important model for future psychiatric research.
Researchers at NYU Tandon School of Engineering propose a paradigm to solve the problem of inferring collective size from individual behaviors. By observing self-propelled Vicsek particles, they show that the time rate of growth of mean square heading is sufficient to predict the number of particles under particular parameters.
Research finds that declining snowpack due to climate change poses significant risks for winter wheat crops, increasing exposure to freeze and agricultural drought. The study's findings highlight the need for improved representation of snow processes in crop models to better understand climate change effects.
Researchers found that states with telehealth reimbursement parity policies had higher rates of face-to-face and virtual contraceptive appointments during the pandemic. The study suggests that increased access to contraception through telehealth may have contributed to improved reproductive health outcomes.
Research by the American Psychological Association found that individuals with high levels of conscientiousness and low neuroticism tend to have better cognitive functioning late in life. Those high in extraversion may also maintain normal cognitive function longer, while high neuroticism is associated with decreased healthy cognition.
The study demonstrates a sulfide coating, amorphous Li2S via ALD, that protects the NMC811 cathode and improves capacity retention, rate performance, and mitigates voltage reduction. The coating also removes O2 released from the NMC cathode during charging.
A new analysis of brain scans from close to 60 people receiving treatment for depression reveals that psilocybin-assisted therapy shows increased brain connectivity even after use, leading to self-reported improvements in depression. The findings differ from conventional antidepressants and suggest a fundamental mechanism via which psy...
The AURORA study found that metastatic breast cancer tumors have distinct genetic and immune feature profiles compared to primary tumors. These differences may lead to more effective treatments by considering individual patient biopsies and biomarkers.
Researchers at UC San Diego found that ovarian cancer tumors activate FAK protein to regulate CD155 expression, creating a shield against immune detection and evading treatment. New molecular targets may boost immune response and lead to new combinatorial strategies for this disease.
Research finds that brain circuit strength is linked to a child's ability to understand numbers. A four-week number sense training program targeting the intraparietal sulcus (IPS) and hippocampus improved learning outcomes for elementary school-aged children across abilities.
Researchers from Osaka University engineered microorganisms to use light as an external energy source, accelerating biomanufacturing of target compounds without disrupting the host microorganism's natural metabolism. This approach has the potential to increase efficiency and reduce carbon emissions in bioprocesses.
A new study found that climate change and drought can lead to increased rates of HIV treatment non-adherence in Africa. The review highlights the complex interactions between social, economic, and environmental factors that exacerbate this issue.
Researchers at Hiroshima University have created the world's first silicon quantum dot (QD) LED light using waste rice husks, offering an eco-friendly alternative to toxic semiconducting materials. The new method transforms agricultural waste into high-quality LED lights with high luminescence efficiency and low environmental impact.
Researchers have developed a new potential COVID-19 treatment using decoy nanoparticles that mimic cells. These nanoparticles effectively inhibit viruses and bind them, rendering them inactive. The treatment has shown promise against drug-resistant variants, outperforming traditional treatments in some cases.
Researchers propose that wildlife can return phosphorus to the land by restoring interconnected animal communities, revitalizing ancient pathways of natural fertilization. This approach aims to generate sources of fertilizer for farmers and increase ecosystem resilience in the face of climate change.
A study by University of Helsinki researchers found that the immune system attacks itself in rare type of blood cancer. The immune system plays a role in the development and growth of cancer cells, making current therapies less effective.
Dr. Mitchell T. Heflin, MD, MHS, is honored with the 2022 Dennis W. Jahnigen Award for his extensive contributions to geriatrics education and healthcare provider training. His work focuses on developing innovative models of care and improving interprofessional collaboration.
A new review estimates that 52% of the global population experience a headache disorder each year, with significant variations in prevalence rates across different age groups and regions. The study also highlights differences in diagnostic methods and their impact on estimated rates.
Researchers identified clofarabine as a promising compound with inhibitory effects on bladder cancer cells, including urothelial carcinoma and sarcomatoid carcinoma. The study suggests potential for clinical trials to treat metastatic bladder cancer patients who cannot receive traditional cisplatin-based therapy.
A survey study found that full FDA approval of the Pfizer-BioNTech COVID-19 vaccine had little immediate impact on vaccination intentions among unvaccinated US adults. The results suggest a lack of urgency or fear driving vaccine hesitancy, instead pointing to concerns over vaccine efficacy and side effects.
Research shows that children aged 9-11 believe farm animals should be treated like pets and think eating animals is less morally acceptable than adults. The study suggests that speciesism - a moral hierarchy giving different value to different animals - is learned during adolescence.
The University of Missouri has received a grant to help nurses discuss COVID-19 vaccination hesitancy with their communities. The project will equip nursing students with knowledge and confidence to promote public health through effective communication strategies.
A new study by UC San Francisco and Imperial College London found that psilocybin therapy reduces connections within brain areas tightly connected in depression, while increasing connections to other regions. This leads to improved depressive symptoms and better cognitive functioning in participants.