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Science News for April 27, 2022


E. coli bacteria exploits Crohn’s disease inflammation

Research finds that intestinal inflammation liberates chemicals that nourish E. coli's growth and promote inflammation, highlighting new treatment targets for Crohn's disease. The study identifies key compounds that feed E. coli, such as phospholipids and amino acids, and shows that these compounds can enhance the bacteria's virulence.

SourceCornell University·JournalJCI Insight·DateApr 27, 2022

Study: Lawyers’ “game framing” of negotiations associated with lower moral character and less honesty

A study by Carnegie Mellon University researchers found that lawyers who view negotiation as a game, with arbitrary rules, are less willing to disclose honest information. Lawyers with higher moral character are more likely to adopt an ethical approach, while those with lower moral character are more prone to game framing.

SourceCarnegie Mellon University·JournalNegotiation Journal·DateApr 27, 2022

Study shows sharing behavior among young children may be related to their counting skills

A new study found that symbolic counting skills are strongly related to young children's fair sharing behavior. Researchers developed a counting intervention that improved sharing behavior in preschoolers, suggesting that learning to count may be a key factor in developing this social skill.

SourceSociety for Research in Child Development·JournalChild Development·TypeObservational study·DateApr 27, 2022

Findings open way for personalised MS treatment

Researchers at Karolinska Institutet have developed a method to identify the immune cells involved in autoimmune diseases and identified four new target molecules for personalized treatment of multiple sclerosis. This approach could lead to more precise treatments with fewer side effects, potentially benefiting other autoimmune diseases.

SourceKarolinska Institutet·JournalScience Advances·DateApr 27, 2022

CNIC scientists discover a new mechanism involved in the modulation of heart muscle elasticity

Researchers have identified a new mechanism involving the oxidation of cysteines in titin protein that modulates cardiac stiffness and dynamics. This discovery sheds light on how the heart adapts to various situations and responds to oxidative balance disorders.

SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalRedox Biology·TypeExperimental study·DateApr 27, 2022

Study shows creativity assessments progressing slowly, including racialized, gendered approaches

A new study from the University of Kansas found that creativity assessments in education rely on standardized approaches, overlooking many students. The research highlights the need for a more diverse range of assessments to identify and encourage creative young people across different domains and populations.

SourceUniversity of Kansas·JournalReview of Research in Education·TypeLiterature review·DateApr 27, 2022

THE LANCET: Global child and adolescent health targets in jeopardy without urgent, comprehensive reform, experts warn

Experts warn that recent progress in child and adolescent health is under threat without comprehensive reform. A holistic approach that spans preconception to adulthood is needed to reduce mortality and improve health outcomes. Strong health systems must partner with social systems to support children's development.

SourceThe Lancet·JournalThe Lancet·TypeSystematic review·DateApr 27, 2022

New data shows burden of dementia symptoms just as high in community population as nursing home residents

Researchers found that people with advanced Alzheimer’s disease and related dementias who live in the community experience similar symptom burdens to those in nursing homes. The study suggests that palliative care interventions could ease symptom burden and improve quality of life for patients and caregivers.

SourceRegenstrief Institute·JournalJournal of Palliative Medicine·DateApr 27, 2022

Is the origin of cultivated kumquat species implicated with Hong Kong kumquat? Probably no.

The study found that cultivated kumquat species have an independent phylogeny among citrus taxa, rejecting the hybridization origin hypothesis. The populations underwent directional selection during their evolutionary trajectory, and the asynchronous population dynamics were earlier than human activity in southern China.

SourceHigher Education Press·JournalFrontiers of Agricultural Science and Engineering·TypeExperimental study·DateApr 27, 2022

Researchers shed light on why a certain plant virus is so powerful at fighting cancer

A team of researchers has discovered that cowpea mosaic virus, when injected into a tumor, triggers a powerful immune response, preventing cancer recurrence. The unique protein shell and RNA structure of the virus activate toll-like receptors, leading to increased cytokine production and a prolonged anti-cancer response.

SourceUniversity of California - San Diego·JournalMolecular Pharmaceutics·DateApr 27, 2022

Electronic skin anticipates and perceives touch from different directions for the first time

Researchers from Chemnitz University of Technology and Leibniz IFW Dresden create a new approach for miniaturizing soft sensor units with integrated artificial hairs. They successfully integrate the 3D magnetic field sensors with magnetically rooted fine hairs into an artificial e-skin, enabling precise spatial arrangement and mass pro...

SourceChemnitz University of Technology·JournalNature Communications·TypeExperimental study·DateApr 27, 2022

People who self-harmed during the COVID-19 pandemic may have been less likely to seek help and have found it harder to access in-patient treatment, according to study of over 3.5 million Welsh citizens

A study of over 3.5 million Welsh citizens found that those who self-harmed during the COVID-19 pandemic were less likely to seek help and faced difficulties accessing in-patient treatment. The research used linked electronic health records to investigate healthcare contacts with self-harm during this period.

SourcePLOS·JournalPLOS ONE·DateApr 27, 2022

UK wildlife watchers welcome 'ecological refugees'

UK wildlife recorders generally welcome newly arrived bird and insect species due to climate change, but have reservations about invasive species that harm native animals. The survey suggests that public opinion plays a crucial role in managing these arrivals, with scientific evidence being a key factor.

SourceUniversity of Exeter·JournalPeople and Nature·TypeSurvey·DateApr 27, 2022

Visual ordinal scoring of coronary artery calcium on chest CT: Diagnostic performance and prognostic utility

A retrospective study found high sensitivity and specificity for diagnosing coronary artery calcium on contrast-enhanced and non-contrast chest CT. The visual ordinal assessment of CAC has prognostic utility, identifying patients at higher risk of cardiovascular events.

SourceAmerican Roentgen Ray Society·JournalAmerican Journal of Roentgenology·TypeObservational study·DateApr 27, 2022

An epigenetic cause of miscarriages is identified and cured in mice

Researchers have identified the Xist gene as a critical regulator of fetal development in mice, leading to miscarriage and abnormal placentas when epigenetic instructions are missing. The study's findings suggest that failed Xist imprinting can be 'cured' by targeting specific genes involved in histone modifications.

SourceRIKEN·JournalGenes & Development·DateApr 27, 2022

Delivery light energy ultra-deep into turbid medium by controlling photons to travel in open channels

Researchers propose new method to enhance light delivery and focusing in scattering mediums, enabling deep imaging and biomedicine applications. The technique uses flying spot Reflection Matrix Optical Coherence Tomography (RMOCT) to separate multiple scattering photons and control their energy.

Wildfires in US, Canadian boreal forests could release sizable amount of remaining global carbon budget

A new study published by the Union of Concerned Scientists warns that wildfires in US and Canadian boreal forests between now and 2050 could release about 12 gigatons of net carbon emissions, equivalent to 3% of the remaining global carbon budget. This could jeopardize nations' ability to limit warming in line with the Paris Agreement.

SourceUnion of Concerned Scientists·JournalScience Advances·TypeObservational study·DateApr 27, 2022

New study offers improved pathways for monitoring and evaluation of climate adaptation conservation initiatives

A new study provides insights on improving monitoring and evaluation of climate-informed conservation projects, highlighting the underutilization of best practices like tying monitoring plans to a theory of change. The research reveals that partnering with external institutions can enhance the comprehensiveness of monitoring efforts.

SourceWildlife Conservation Society·JournalConservation Science and Practice·TypeMeta-analysis·DateApr 27, 2022

NIH awards $2.4 million grant to The University of Texas Health Science Center at San Antonio and ADA Science & Research Institute to study responsible antibiotic use

The NIH-funded study will enroll 1,050 patients with periodontitis to collect data on the efficacy of antibiotics in treating the condition. The goal is to develop evidence-based clinical guidelines and advance oral health, particularly given the critical need to reduce antibiotic misuse and combat superbugs.

Artificial intelligence aids to diagnose mild cognitive impairment that progresses to Alzheimer's

A new AI-based method distinguishes between stable and progressive cognitive impairment, enabling accurate diagnosis with an accuracy rate of 85%. This technique overcomes the complexity of subtle structural changes in mild cognitive impairment, contributing to achieving Sustainable Development Goal 3.

SourceUniversitat Oberta de Catalunya (UOC)·JournalIEEE Journal of Biomedical and Health Informatics·DateApr 27, 2022

Plug-and-play organ-on-a-chip can be customized to the patient

Researchers from Columbia University have developed a plug-and-play multi-organ chip, customized to the patient, consisting of engineered human heart, bone, liver, and skin linked by vascular flow. The model allows for long-term studies and can be optimized for personalized therapy optimization in cancer and systemic diseases.

SourceColumbia University School of Engineering and Applied Science·JournalNature Biomedical Engineering·DateApr 27, 2022

The Trump baby bump among Republicans after the 2016 election

Research from the University of California San Diego finds a significant partisan shift in birth rates among Republicans and Democrats after Trump's 2016 election. Republican-leaning counties experienced a sharp rise in birth rates, while Democratic counties saw a baby slump, with differences amounting to 1-2% of national birth rates.

SourceUniversity of California - San Diego·JournalAmerican Economic Review·TypeData/statistical analysis·DateApr 27, 2022

Study of privately insured patients finds short-term telehealth follow-up comparable to most in-person care during first year of COVID-19 pandemic

For 18 out of 21 analyzed conditions, patients with telehealth consults did not require more unplanned hospitalizations or emergency department visits within 14 days compared to those making an initial in-person visit. However, patients with upper respiratory infections and bronchitis were more likely to need follow-up visits.

Researchers realize topological quantum simulation based on synthetic orbital angular momentum dimension in degenerate cavity

Scientists create artificial lattice structure with infinite topological charge numbers by coupling photons' spin-orbit coupling to internal degrees of freedom. The setup allows direct measurement of physical quantities and paves the way for exploring high-dimension topological physics.

SourceUniversity of Science and Technology of China·JournalNature Communications·DateApr 27, 2022

Yale researchers have a formula for getting in the flow

Yale University psychologists have developed a mathematical theory of flow that can be used to enhance immersion and engagement in almost any task. The theory is based on the concept of mutual information between desired end states and means of attaining them, and suggests that more informative means lead to greater flow experience.

SourceYale University·JournalNature Communications·DateApr 27, 2022

Tangle no more, nanotubes

Researchers develop less-corrosive solutions using methanesulfonic acid, p-toluenesulfonic acid and oleum acids to separate and process nanotubes. The new method enables scalable production of advanced materials with excellent electrical and mechanical properties.

SourceRice University·JournalScience Advances·TypeExperimental study·DateApr 27, 2022

Zeroing in on a new treatment for autism and epilepsy

Scientists at Gladstone Institutes have discovered that reducing protein tau levels soon after birth can prevent autism and epilepsy in an experimental model. The study pinpointed the crucial brain cells where tau levels must be reduced to avoid these problems, and showed that lowering tau is still effective when initiated after birth.

SourceGladstone Institutes·JournalScience Translational Medicine·DateApr 27, 2022

Scientists find a genetic cause of lupus

Researchers have identified a genetic cause of lupus, a chronic autoimmune disease that affects 50,000 people in the UK. The TLR7 gene mutation causes inflammation in organs and joints, leading to debilitating symptoms. This discovery paves the way for new treatments targeting the mutated gene.

SourceThe Francis Crick Institute·JournalNature·TypeExperimental study·DateApr 27, 2022

Decoy receptor protects against Omicron infection

Researchers from Osaka University have developed an engineered ACE2 decoy that effectively reduces the rate and severity of infection with the Omicron variant under laboratory conditions. The decoy mimics the SARS-CoV-2 receptor, preventing the virus from binding to cells and entering them.

SourceOsaka University·JournalScience Translational Medicine·TypeExperimental study·DateApr 27, 2022

Synthetic “forever chemicals” known as PFAS linked to liver damage

A new study systematically reviews data on PFAS exposure and liver damage, linking three commonly detected PFAS to elevated levels of a liver enzyme, ALT. The research suggests a potential link between PFAS and non-alcoholic fatty liver disease (NAFLD), a growing public health crisis affecting 25% of adults worldwide.

SourceKeck School of Medicine of USC·JournalEnvironmental Health Perspectives·TypeMeta-analysis·DateApr 27, 2022

Mental health of college students is getting worse

A recent study found a consistent decline in the mental health of college students across the US over eight years, with significant increases in depression and anxiety among racial and ethnic minority students. The study also revealed a gap between symptom onset and treatment access, particularly for students of color.

SourceBoston University·JournalJournal of Affective Disorders·DateApr 27, 2022

Glimpse inside a graphene sandwich

Researchers studied twisted trilayer graphene, discovering a phase diagram that decouples into product states of graphene and bilayer graphene. The system exhibits unique insulating and semi-metallic phases in the presence of an electric field.

SourceUniversity of Innsbruck·JournalPhysical Review X·TypeComputational simulation/modeling·DateApr 27, 2022

Solar beats nuclear at many potential settlement sites on Mars

A new study by UC Berkeley scientists finds that solar photovoltaics can provide sufficient power for extended Mars missions, outperforming nuclear fusion reactors in over 50% of the planet's surface. This breakthrough provides a more practical solution for long-term human settlements on Mars.

SourceUniversity of California - Berkeley·JournalFrontiers in Astronomy and Space Sciences·TypeComputational simulation/modeling·DateApr 27, 2022

Almost 90% of autistic women report experiencing sexual violence, often on multiple occasions

A new study published in Frontiers in Behavioral Neuroscience reveals that nine out of ten autistic women in France have suffered sexual violence, with most victims being assaulted multiple times at a young age. The findings highlight the need for improved prevention and care programs to address this vulnerable population.

SourceFrontiers·JournalFrontiers in Behavioral Neuroscience·TypeSurvey·DateApr 27, 2022

Brain imaging shows what happens when we question fake news

A new study from the University of Texas at Austin finds that asking a single question about article truthfulness can activate the brain's critical thinking centers, challenging biases and encouraging more critical evaluation of content. This finding has implications for social media companies looking to curb the spread of misinformation.

SourceUniversity of Texas at Austin·JournalInformation Systems Research·TypeExperimental study·DateApr 27, 2022

Study reveals genetic diversity of a particularly problematic pathogen

Researchers analyzed 451 bacterial strains of C. difficile, identifying 9,924 distinct gene clusters and categorizing them into 176 genetically distinct groups. The study provides new insights into the genetic diversity and evolution of this pathogen, shedding light on its virulence factors and antimicrobial resistance determinants.

SourceUniversity of California - San Diego·JournalProceedings of the National Academy of Sciences·DateApr 27, 2022

Nanoplastic particles love company: Researchers in Bayreuth analyze polyethylene degradation in the environment

A research team from the University of Bayreuth investigated the progressive degradation of low-density polyethylene in the environment. They found that isolated nanoplastic particles are rare and instead aggregate rapidly to larger colloidal systems, preventing individual nanoparticles from being freely available.

SourceUniversität Bayreuth·JournalScience of The Total Environment·TypeNews article·DateApr 27, 2022

Highly efficient Fe³⁺-doped A₂BB’O₆ broadband near-infrared-emitting phosphors for spectroscopic analysis

Researchers have developed Fe³⁺-activated Sr₂InSbO₆ broadband NIR-emitting phosphor materials with tunable emission from 885 to 1005 nm. The Ca2InSbO6:Fe3+ phosphor peaking at 935 nm shows an ultra-high IQE of 87%, making it suitable for NIR spectroscopy detection.

Origin of complex cells started without oxygen

Eukaryotes emerged in an anoxic environment in the ocean, and their mitochondria-bearing cells likely resulted from a merger between archaea and bacteria. This finding contradicts the long-held view that oxygenation of Earth's surface environment led to eukaryogenesis.

SourceUniversity of Exeter·JournalNature Ecology & Evolution·TypeLiterature review·DateApr 27, 2022

Bat box design, placement matter for energy balance in endangered bats

Research finds that bat box design and landscape placement significantly impact the energetic balance of endangered Indiana bats. A study by University of Illinois researchers tested five bat box designs and four landscape placements to determine their effects on bat metabolism, development, and survival.

Green technology breakthrough: Hematite photocatalyst using sunlight energy simultaneously produces hydrogen and hydrogen peroxide

A breakthrough in green technology has successfully produced both hydrogen gas and hydrogen peroxide simultaneously from sunlight and water using a hematite photocatalyst. This innovation could lead to a solar water-splitting utilization system with greater added value, enabling the widespread adoption of carbon-neutral energy sources.

SourceKobe University·JournalNature Communications·TypeExperimental study·DateApr 27, 2022

Anesthetic drastically diverts the travels of brain waves

A new study by MIT scientists reveals that propofol anesthesia significantly alters the state of brain waves, with lower frequency delta waves dominating. Higher frequency beta waves decrease in structure and power, with their traveling nature disrupted by the surging delta waves. The findings suggest a profound impact on consciousness.

SourcePicower Institute at MIT·JournalJournal of Cognitive Neuroscience·TypeExperimental study·DateApr 27, 2022

Student research solves an icy dwarf planet mystery

A team of researchers from Brigham Young University has solved the mystery of Haumea's origin by re-evaluating assumptions about its formation. By considering the dwarf planet in the context of the broader solar system creation, they proposed a new explanation that explains why Haumea is one of the fastest spinning objects and covered ...

SourceBrigham Young University·JournalNature Communications·TypeComputational simulation/modeling·DateApr 27, 2022

Hitting new heights

A UC Santa Barbara-designed mechanical jumper has achieved a record-breaking 100-foot height, thanks to the innovative application of 'work multiplication' and a novel hybrid spring design. The device overcomes biological limitations, enabling efficient locomotion in challenging environments.

Moffitt researchers develop model to predict patients with poor lung cancer outcomes

Researchers developed a model using radiomic features from screening images to identify high-risk lung cancer patients. The model divided patients into groups according to their risk of having poor outcomes, with low-risk patients having an 83.3% five-year overall survival and high-risk patients having a 25% five-year overall survival.

SourceH. Lee Moffitt Cancer Center & Research Institute·JournalCancer Biomarkers·TypeImaging analysis·DateApr 27, 2022

Study shows importance of ensuring participant and provider follow-up after a genetic screening result

A study from the Healthy Nevada Project found that only 10% of patients with electronic health records containing genetic diagnosis experienced a change in care, emphasizing the need for follow-up education and conversations. The study also highlights the importance of including genetic diagnoses into electronic health records to maxim...

SourceDesert Research Institute·JournalFrontiers in Genetics·TypeSurvey·DateApr 27, 2022

“Keto” molecule may be useful in preventing and treating colorectal cancer, Penn study suggests

Researchers found that a molecule called beta-hydroxybutyrate (BHB) produced in the liver during low-carb diets can suppress colorectal tumor growth. BHB's anti-tumor effects were replicated by giving mice the molecule directly, indicating its potential as a preventive and treatment for colorectal cancer.

SourceUniversity of Pennsylvania School of Medicine·JournalNature·TypeExperimental study·DateApr 27, 2022

A refined microbiome “fingerprint” method tracks sub-strain variants of a single gut microbe strain

Researchers develop a refined microbiome fingerprint method to track sub-strain variations in key gut bacteria species. The study found differences in sub-strain dynamics between healthy individuals and hospitalized COVID-19 patients, suggesting an impending shift in the dominant strains of the gut microbiome.

SourceUniversity of Alabama at Birmingham·JournalScientific Reports·TypeData/statistical analysis·DateApr 27, 2022

Language that belittles or blames patients is overdue for change

Using positive language in clinical practice can alter attitudes of both patients and physicians, fostering a relationship focused on shared understanding and collective goals. Language that casts doubt, belittles, or blames patients affects therapeutic relationships by altering patient behaviors.

SourceBMJ Group·JournalThe BMJ·TypeData/statistical analysis·DateApr 27, 2022