People with rheumatoid arthritis have a higher risk of cardiovascular disease due to inflammation. However, new research suggests that commonly used treatments for RA can also lower this risk by reducing arterial inflammation and disease activity. The study found that immunomodulators like methotrexate and TNFi drugs reduced heart dise...
The NASA Deep Space Optical Communications project has successfully demonstrated a new type of laser system that can transmit large amounts of data, including high-definition images and video, through space. The system uses a combination of flight and ground-based lasers to establish an optical link between spacecraft and Earth.
Researchers developed a new method to target diseased neurons using light, changing their long-term behavior. The approach uses light-sensitive enzymes to create insulating or conductive coatings on cell membranes, tuning excitability in neurons.
Researchers developed a quantum receiver that uses adaptive learning to improve signal decoding in noisy environments. The upgraded receiver achieved record-high efficiency and robust interference visibility, with improved performance compared to conventional designs.
Researchers at Tsinghua University developed a high-conductivity material, molybdenum disulfide (MoS2), that reduces contact resistance and improves Schottky barrier height in microchips. The team's innovative method uses epitaxial van der Waals contacts to achieve promising results.
Researchers used bright green lasers and camera equipment to directly visualize aerosol plumes and measure the speed and spread of particles in a toilet flush. The study found that airborne particles shoot out quickly, reaching speeds of 6.6 feet per second and remaining suspended in the air for minutes or longer.
Researchers at UCSF and IBM Research create a predictive model that encodes commands for cells to kill cancer cells. By combining words that guide engineered immune cells, they can predict which elements should be included in a cell to carry out precise behaviors. This advance allows scientists to rapidly design new cellular therapies.
A new study found that suicidal ideation increased by nearly five times during the pandemic, particularly among people living in low-income households and those struggling with loneliness. The study highlights the need for policies and programs providing financial and social support to vulnerable populations.
A study by the American Museum of Natural History and collaborators classifies the world's simplest animals, placozoans, using genetic makeup, revealing distinct lineages and relationships to cnidarians and bilaterians. The research establishes a backbone taxonomy for the phylum, providing insight into their evolution and diversity.
The University of Birmingham has developed a validated symptom burden questionnaire for Long COVID, which can now be translated into hundreds of languages. The questionnaire, called SBQ-Long COVID, aims to capture the complexities of Long COVID and develop or test new treatments.
Researchers at the University of Münster developed a new way to produce vicinal diamines, which are crucial for biologically active molecules and drugs. The process uses light energy from blue LEDs to produce these unsymmetrically constructed compounds without using transition metals.
Researchers at Johns Hopkins Medicine discovered that regulating the electrical charge on the inner side of the cell membrane can activate pathways responsible for cell movement. This finding has potential implications for understanding cancer cell migration and immune cell function.
A USTC research team achieved on-demand storage of photonic qubits at telecom wavelengths using a laser-written waveguide fabricated in an erbium-doped crystal. This innovation increases photon storage efficiency by up to fivefold, reaching 98.3% fidelity and enabling large-scale quantum networking applications.
A quality improvement program assisted patients in overcoming video visit access barriers, leading to improved adherence rates. The study found a significant association with both increased video visit attendance and financial savings.
Researchers discovered that 55 Cnc e orbits its star along the equator, unlike other planets in the system. This unique orbit likely formed when the planet fell toward its star over time, resulting in a scorching surface and interior with possible diamond formation.
Researchers at NIST have measured the 3D orientation of polymer chains in plastics, observing complex patterns that dictate material properties. The new technique uses polarization-controlled coherent Raman microscopy to identify molecular orientation patterns, allowing for optimized materials in industries like medicine and electronics.
A new study provides fine-scale maps to guide action towards protecting Oregon's forests, which are among the highest carbon density in the world. The research aims to increase carbon storage while protecting wildlife and clean water.
Researchers used genomic data from over 4,000 dogs to identify 10 major lineages and behavioral traits that correlate with these lineages. The study found that genomic variations among dog breeds are related to the development of their nervous system, suggesting a link between canine and human brain function.
Researchers at Baylor College of Medicine discovered that oxytocin drives the development of neural connections in adult-born neurons. Oxytocin triggers a signaling pathway that promotes synapse maturation, enabling these new neurons to function properly.
A recent astronomical observation supports theoretical modeling, revealing a new observational fingerprint of neutron-star mergers that may shed light on the production of heavy elements throughout the universe. The detection pushes our understanding of gamma-ray bursts to the limits and breaks the standard idea of these events.
A study by Hokkaido University reveals that the El Niño Southern Oscillation (ENSO) has caused more frequent heavy rainfall in the Mekong Delta, resulting in increased flooding risk. The findings suggest that better weather predictions and preparation can help mitigate the negative effects of floods and droughts in the region.
A husband-and-wife research team at UC Riverside found a simpler gene network is involved in specifying the gut in nematodes related to Caenorhabditis elegans. The discovery was made possible by the COVID-19 pandemic, which freed up time for the researchers to explore their question of how nematodes develop their gut.
Researchers found that germicidal UV lamps can significantly decrease SARS-CoV-2 virus transmission risk, but also produce secondary VOCs and particulate matter, impacting indoor air quality. The study recommends using GUV systems in high-risk environments where benefits outweigh drawbacks.
Researchers used WGS data of 10,585 people from China to construct the first blood virological profile of the Chinese population. The study identified 14 viruses widely present in the population, including hepatitis B virus, which was detected in 1.69% of individuals.
A new undergraduate research program at the University of Arizona aims to address local health issues in Arizona using a community-based approach. The PHIRE program recruits 60 students annually for training in health informatics and places them in research projects relevant to their communities.
Researchers have identified three new genes, SHMT1, FAM120B, and ICA1L, and their expressed proteins that may be involved in the development of multiple sclerosis. The study provides new insights into the mechanisms underlying the disease and prioritizes promising targets for future therapy research.
Researchers have made a breakthrough in producing infectious Plasmodium falciparum sporozoites without the need for mosquitoes, paving the way for more effective malaria vaccines. This achievement accelerates the ability to study the parasite's biology and develop new tools for vaccine development.
Researchers found that a vaccine against the toxin produced by E. coli protects infant mice from intestinal damage, suggesting it could boost global efforts to combat childhood malnutrition. Vaccinating kids against E. coli diarrhea may prevent long-term effects like stunting and micronutrient deficiencies.
The SURGE Topical Theory Collaboration aims to develop calculations and a theoretical framework for discovering the saturated state of gluons. Scientists hope to gain deeper insight into the strong force and gluons' role in generating hadron properties.
Two independent teams of astronomers detected the unexpected hallmarks of a kilonova after a long gamma-ray burst, challenging the prevailing theory that long GRBs exclusively come from supernovae. The discovery was made possible by the proximity of the event and the sensitivity of telescopes like Gemini North.
A 120-million-year-old bird fossil called Yuanchuavis kompsosoura reveals a mosaic of dinosaurian and bird traits, including a feathered body with wings, a toothed mouth, and an immovable dinosaurian palate. The study provides clues about the origin of cranial kinesis, a fundamental feature of modern bird skulls.
Researchers found particulate air pollution concentrations between 10 to 20 times higher inside the Copenhagen Metro system compared to street level. The concentrations measured at stations were 109-168 µg m−3, exceeding EU's 25 µg m−3 standard.
In Germany, community participation in decision-making processes and sharing of financial benefits from renewables projects enhanced public support. However, recent delays and corporate investments have led to resentment. In contrast, Australia's decentralized approach to its power grid, including community energy projects, aims to bri...
Researchers at UMass Amherst calculated pre-agricultural soil erosion rates in the Midwest, finding them to be 0.04 mm per year, significantly lower than the USDA's current limit of 1 mm per year. Modern agriculture has accelerated erosion rates, threatening topsoil and global food security.
The City of Tempe and Arizona State University have developed a unique partnership to track COVID-19 using wastewater-based epidemiology, providing early warning data for municipalities. The system has been shown to reliably predict SARS-CoV-2 levels in city ZIP codes up to 11 days ahead of clinical testing results.
A study by Sanford Burnham Prebys found that misfolded proteins in liver cells contribute to liver cancer development, potentially increasing the risk of certain patients receiving gene therapies for hemophilia. Improving FVIII folding could decrease this risk and develop safer treatments.
A KAUST research team studied the interaction between nitrogen gas and hydrocarbons in oil reservoirs. They found a direct correlation between nitrogen solubility and oil swelling, enhancing oil recovery. The study also sheds light on CO2 storage with impurities like methane and nitrogen.
A study published in the Journal of Medical Imaging and Radiation Sciences found that hospital parking fees significantly correlate with cancer center address transit score and city cost of living across Western Canada. Cities with higher cost of living have less free parking, exacerbating economic burdens on patients.
A study published in the Journal of Dentistry found that patients with unexplained brain abscesses were three times more likely to have oral bacteria present. The researchers also discovered significantly higher counts of Streptococcus anginosus, a bacterium linked to dental abscesses and infections in internal organs.
The phase 1 and phase 2 studies showed that ARV-471 was well-tolerated and could promote substantial estrogen receptor degradation in patients with advanced disease. The study has led to a randomized phase 3 trial comparing ARV-471 with a SERD in patients with ER-positive/HER2-negative advanced breast cancer.
Researchers create a soft robot that can detect damage and heal itself using stretchable fiber-optic sensors and polyurethane urea elastomer. The SHeaLDS technology provides a damage-resistant robot that can self-heal from cuts, and the researchers plan to integrate it with machine learning algorithms for more tasks.
A UCLA-developed wearable patch analyzes fluid underneath the skin to continuously record medicine concentrations in the body. The technology shows reliable forecasts of total effective medication delivery, offering a step toward improving doctors' ability to administer precise doses.
A study on the flagellate Angomonas deanei reveals how host cells control their bacterial symbionts through protein transfer. This process enabled the bacteria to become cell organelles, such as mitochondria and chloroplasts, with reduced genomes and controlled metabolism.
A large-scale study has found a clear relationship between the composition of the microbiome and depression. A diverse microbiome was associated with lower rates of depression, while an underrepresented microbiome was linked to increased depressive symptoms. This association is as strong as established risk factors for depression.
A study by Michael Hurd and Susann Rohwedder found that real spending adjusted for inflation declined at annual rates of about 1.7% and 2.4% after age 65, contradicting traditional wisdom that spending will increase during older age.
A University of California Riverside study found that Salton Sea dust triggers lung neutrophil inflammation in mice, with potential implications for asthma sufferers and other terminal lake regions. The research highlights the need for further funding to understand dust-triggered inflammation and its effects on human health.
A phase II clinical trial evaluating neoadjuvant trastuzumab deruxtecan in patients with hormone receptor-positive, HER2-low breast cancer demonstrated a 75% overall response rate. The study also showed that T-DXd was relatively safe and may provide a translational framework for future studies on combination regimens.
Researchers develop new method to identify crucial protein fragments driving autoimmunity, enabling better diagnostics and therapies. The study finds cross-reactivity between human and microbial proteins drives autoimmunity in at least two diseases.
A large genetic study found that more than 2,300 genes predict alcohol and tobacco use behaviors, with a majority shared among people of European, African, American, and Asian ancestries. The study's findings have the potential to identify individuals at high risk for substance misuse.
A new study by the University of East Anglia highlights the risks of relying on nature-based solutions, such as forests and soils, to achieve net-zero emissions. The research warns that these solutions may not be enough to offset the remaining difficult-to-decarbonize emissions if progress on reducing fossil fuel use stalls.
Researchers have developed a scaled-up version of a probabilistic computer using stochastic spintronic devices, suitable for combinatorial optimization and machine learning. The new design combines conventional semiconductor chips with modified spintronic devices, achieving massive improvements in throughput and power consumption.
A new study by University of Toronto researchers found that a strong majority of those diagnosed with COPD were in excellent mental health. 87% of older Canadians with COPD had no mental illness, highlighting the importance of social support and interventions to promote well-being.
Researchers developed magnetic microrobots that can bind and isolate S. aureus from milk, improving dairy safety. The 'MagRobots' use antibodies to target the bacteria, allowing for efficient pathogen isolation while preserving naturally occurring microbes.
Administration of vaccine boosters to nursing home residents significantly reduces SARS-CoV-2 infections and hospitalizations. The study suggests that booster vaccination may play a crucial role in preventing COVID-19-related morbidity and mortality among vulnerable populations.
A longitudinal study from UMass Amherst reveals that peer mentorship enhances female engineering students' confidence, motivation, and academic outcomes. The study, which tracked 150 female students over eight years, showed that female mentees with female mentors reported greater belonging, motivation, and confidence.
A recent study published in Molecular Psychiatry reveals a genetic link between attention-deficit/hyperactivity disorder (ADHD) and Alzheimer's disease in older adults. Researchers used a polygenic risk score to analyze the relationship between ADHD genetic predisposition and cognitive decline, finding a higher risk of developing Alzhe...
Researchers found that dietary saturated/trans fats, but not cholesterol, can trigger hepatic angiogenesis and lymphangiogenesis in mice, leading to the promotion of hepatic tumors. This process is driven by the JNK-HIF1α-VEGF-C axis.
Researchers at the Salk Institute have identified mechanisms that activate oncogenes in cancer cells, providing insights into predicting and treating the disease. The study found that structural variants in DNA can impact gene expression, leading to cancer, but most variants have no effect.
Alzheimer's disease is a growing health concern, affecting two-thirds of dementia patients. Prof. Michael Heneka's MINIALZ project aims to study immune cells and neurons in the brain to better understand disease progression and develop new diagnostic tools.
A research team used photogrammetry to build 3D models of flowers from two-dimensional images, gaining new insights into the shape and color of flowers. The technique allows for detailed study of flowers' morphology and colors, which act like magnets to attract pollinators.