The Princeton Plasma Physics Laboratory has been awarded $5 million to lead an Energy Earthshot Research Center focused on producing clean hydrogen. The center aims to reduce the cost of hydrogen by 80% and could lead to a paradigm shift in clean hydrogen production.
A machine learning model developed by researchers can predict lung cancer risk with an 83.9% sensitivity, identifying those who need screening for the disease. The model uses just three predictors: age, smoking duration, and pack-years of smoking, making it a simplified approach to determine high-risk populations.
A new study reveals that independent physician practices experienced a smaller drop in patient volume than their larger counterparts during the height of the COVID-19 pandemic. This finding suggests that independent practices can thrive and provide quality care to patients with chronic conditions.
Researchers at the University of Southern Denmark have conducted a study on rats, showing that small doses of psilocybin can increase resilience to stress and reduce compulsive behaviors. The study lends support to the benefits of microdosing as a therapeutic intervention.
Utilization and spending on mental health services for children and youths with commercial insurance significantly increased from January 2019 to August 2022. Attention-deficit/hyperactivity disorder, anxiety disorders, and adjustment disorder accounted for most visits and spending across all phases of the study.
A recent study by the University of Melbourne found that severe bushfires followed by heavy rainfall are causing platypuses to abandon their homes. The research used environmental DNA sampling to track platypus movement before and after the 2019-2020 megafires, revealing a significant decline in platypus populations in affected areas.
Duke researchers demonstrate that incorporating rhythm into movement designs can optimize performance and efficiency for robots and animals. By varying the timing of movements, optimal rhythms can be achieved, affecting all aspects of design.
The Illinois-led project will sequence at least 50 soybean genomes from cultivated lines and wild relatives, as well as 350 high-quality draft genomes. This will enable the identification of genetic variation and its incorporation into better crops, ultimately leading to climate-resilient soybean varieties.
A new study has detected high levels of bacterial resistance to antibiotics in two Australian aged care facilities, highlighting a concerning trend in the sector. The study used wastewater-based surveillance to detect antimicrobial resistance in Escherichia coli and found above-average levels of gentamicin resistance in one facility.
Researchers at Kyoto University discovered that liverwort Marchantia polymorpha uses gibberellin precursors to produce a signaling molecule aiding survival under shaded conditions. This metabolic pathway inheritance provides insight into the evolution of plant hormone responses.
Researchers discovered a cell signaling pathway that allows effector memory T cells to drive innate cytokine storms in autoimmune diseases. Targeting the STING pathway may prevent inflammation chain reactions, offering new hope for treating conditions like type 1 diabetes and rheumatoid arthritis.
Researchers have developed an oral lipid nanoparticle drug that prevents tumor development in mice, demonstrating its potential as a treatment for colitis-associated cancer. The study, led by Georgia State University researchers, used M13-loaded nanoliposomes to target diseased tissue and reduce side effects.
New research finds that cigarette smoking increases the risk of developing type 2 diabetes by affecting various metabolites in the bloodstream. A unique metabolic signature, identified through analysis of over 93,000 UK Biobank participants, can predict which smokers are more likely to develop the condition.
Researchers at the Technion have made a breakthrough in understanding sporadic Alzheimer's disease by identifying the mechanism behind protein accumulation. The study found that damage to the ubiquitin system leads to the accumulation of toxic proteins, even in healthy tissue, mimicking typical Alzheimer's pathology.
Research suggests that universal screening for type 1 diabetes at two ages could predict most cases of T1D by age 15. Dr. Emily K. Sims emphasizes the importance of identifying individuals with early, presymptomatic stages of disease to prevent life-threatening episodes and improve outcomes.
Researchers have identified a specific area of the amygdala brain region that can cause prolonged loss of breathing after a seizure. This finding offers new insight into the mechanisms underlying Sudden Unexpected Death in Epilepsy (SUDEP), a rare but fatal complication of epilepsy.
A 15-minute reflection exercise strengthens job seekers' belief in themselves, making them more effective applicants. The study found that this self-reflection increased the chances of finding a job, even for those over 50 and long-term unemployed.
Recent satellite deployments have reached record-breaking brightness levels, posing a threat to ground-based astronomy. The addition of 400,000 satellites in the near future could completely alter the night sky.
Researchers developed a new base modification, Z-mRNA, that demonstrates low immunogenicity and reduced cytotoxicity compared to unmodified mRNAs. The modified mRNA can induce a substantial immune response and has potential therapeutic applications beyond COVID-19 vaccines.
Spending on mental health services for children and adolescents increased by 26% from March 2020 to August 2022, with telehealth use rising 30-fold during the early pandemic phase. In-person care returned to 75% of pre-pandemic levels by August 2022.
Scientists at IISc have developed an enzyme mimetic called NanoPtA that can degrade toxic chemicals in industrial wastewater effectively in the presence of sunlight. The nanozyme is highly specific and robust, making it suitable for large-scale industrial use.
A study by Duke University psychologists finds that White people tend to see Multiracial faces as Black, while Black people see them as White. Multiracial participants show less bias when forced to choose one race, categorizing faces as White more often than Black.
Diagnosed with type 2 diabetes at age 30 can lead to a reduced life expectancy of up to 14 years due to complications such as heart attack, stroke, and cancer. The analysis found that every decade of earlier diagnosis was associated with about four years of reduced life expectancy.
Ecologists say that carbon-capture tree plantations have a negative impact on tropical biodiversity and ecosystem services, despite their potential to offset climate change. In contrast, intact ecosystems like forests, grasslands, and savannahs store large quantities of carbon below ground and provide multiple ecosystem services.
Researchers at Northwestern University developed Lattice, a device that simulates human disease in multiple organs to analyze interactions and test new drugs. The technology can replicate complex disease processes, allowing scientists to study the effects of obesity on endometrial cancer, for example.
A Cornell-led collaboration created a 3D in-vitro model of human lymphatic vessels that revealed a surprising mechanism jamming up drainage: the protein ROCK2. Inhibiting ROCK2 reverses lymphedema effects, offering potential treatment for this condition.
Researchers discovered that around 13% of brain proteins differ between males and females, with some proteins more abundant in females and others in males. The study also found that genetic variation influences protein expression, with sex-related differences prominent at the protein level.
A team from Kanazawa University and international partners report their groundbreaking study on dynamic friction, shedding light on the force needed to maintain molecule movement. The research provides fresh insights into a long-studied phenomenon and paves the way for future studies on energy dissipation relaxation processes.
Researchers at CABBI developed an economical method for producing succinic acid, a key chemical in food, agricultural, and pharmaceutical products, using acid-tolerant yeast. The new pipeline eliminates costly downstream processing steps, significantly reducing costs and emissions.
A Northwestern University-led team of astrophysicists has discovered that young galaxies appear brighter than anticipated due to irregular bursts of star formation. This finding explains the puzzling appearance of massive galaxies too soon after the Big Bang, fitting within the standard model of cosmology.
University of Minnesota researchers identified top-performing primary care practices that deliver high-quality diabetes care through proactive patient outreach. These practices prioritize good communication and engagement with patients, fostering a strong doctor-patient relationship essential for overall health.
A recent study reveals that emerging infectious diseases are accumulating rapidly globally, particularly in Holarctic trees. The 'big data' approach used in the study characterizes the growing threat posed by emergent infectious diseases, with some tree species, such as pines and oaks, showing high new disease accumulation.
Researchers have developed a synthetic peptide that could help reduce vascular problems associated with acute respiratory distress syndrome in COVID-19. The peptide, called TIP, works by binding to a subunit of the epithelial sodium channel, which helps maintain barrier function and prevent damage from viral proteins.
A study published in Diabetes Care found that obesity, hypertension, and dyslipidemia alter cardiac energy production by interfering with metabolic substrate uptake. The research reveals early changes in apparently healthy middle-aged individuals, highlighting the importance of identifying mechanisms involved in heart disease onset.
Rice University bioengineers Jerzy Szablowski and Julea Vlassakis have received the National Institutes of Health Director’s New Innovator Award for their creative research projects on gene expression and cancer interactions. Szablowski is developing noninvasive methods to map gene expression, while Vlassakis is studying complex single...
A recent study found that households headed by single women of color in Brazil are four times more likely to experience food insecurity compared to those headed by married white men. The researchers argue that policies addressing gender equality, antiracism, and family considerations can help reduce poverty and hunger.
In a randomized clinical trial, weekly tirzepatide showed greater reductions in HbA1c levels and body weight compared to prandial insulin as an additional treatment in people with inadequately controlled type 2 diabetes. The study also found less hypoglycemia with tirzepatide.
Dr. On-Yee Lo receives $50,000 seed funding to develop personalized non-invasive brain stimulation targeting shared networks to improve physical and cognitive functions in older adults. The project aims to demonstrate direct evidence that modulating between-network connectivity can be linked to changes in physical and cognitive behaviors.
Researchers have developed a wearable sensor patch capable of continuously monitoring vancomycin levels, a critical antibiotic used to treat severe bacterial infections. The sensor system detects changes in vancomycin concentration using aptamers and gold wires, providing real-time measurements for effective treatment.
State hospital regulations encouraging breastfeeding increased breastfeeding rates by 4% and up to 7%, but also reduced mothers' labor force participation by 3%. The policies have been shown to benefit women with higher education and incomes, but may not necessarily provide a health benefit due to confounding factors.
A randomized clinical trial found that early metformin treatment did not improve insulin initiation or fasting glucose levels in pregnant women with gestational diabetes. Further investigation into larger trials is warranted based on prespecified secondary outcome data.
A real-world study confirms the reliability and effectiveness of the Pooled Cohort Equation (PCE) in assessing cardiovascular risk, regardless of statin use. The PCE performed well across different demographics and retained accuracy with measurement factors outside its original risk profile range.
A new study by UCLA climate scientist Daniel Swain finds that climate change is limiting the use of prescribed fires to prevent wildfires. The research projects a 17% reduction in favorable days across the Western US, with most reductions coming in spring and summer.
Researchers discovered that monk parakeets possess a unique tone of voice, known as a voice print, similar to humans. This finding raises the possibility that other vocally flexible species may also have a voice print.
Researchers add graphene to Bi-2223 superconductors, increasing critical current density and improving phase formation. The findings suggest potential applications in various fields, including power generation, transportation, and quantum computing.
A new study published in JAMA found that a consensus-based risk-stratification algorithm reduced unnecessary ovary removals in girls with benign masses from 16.1% to 8.4%. The algorithm accurately identified lesions highly likely to be benign, allowing for ovary-sparing surgery.
A new SwRI study posits that the large mounds on Kuiper Belt object Arrokoth are similar in size and shape, suggesting a common origin. This finding supports the streaming instability model of planetesimal formation, where gentle collision speeds allowed objects to accumulate and form Arrokoth.
Scientists at Johns Hopkins Medicine have identified a protein mutation in CD8+ T cells that can make them more effective against cancer and infections. The mutated T cells were found to be more active when stimulated, persist longer, and expand in great numbers during the initial immune response.
The research aims to understand the molecular response of plants to environmental stress by investigating the connection between two independent biochemical signaling pathways, ethylene biosynthesis and autophagy. The findings could lead to the development of high-yield, pathogen-resistant, stress-tolerant plants.
A new AI-based predictive tool called PARMESAN helps scientists discover potential treatments for genetic disorders by analyzing public biomedical literature databases. The tool assigns weighted scores to gene-protein interactions, identifying promising drugs and accelerating research speed.
Researchers at DESY have developed a method to deflect laser beams in air without contact, preserving the beam's quality. The technique uses acoustic density waves to create an invisible grating that changes the direction of the laser light.
A novel liquid biopsy test identifies levels of circulating tumor DNA as a more precise measure of disease burden than the number of tumors themselves. Patients with lower levels of detectable ctDNA are more likely to benefit from radiation therapy.
A new study reveals the critical importance of post-transcriptional processes in regulating circadian rhythms and their impact on sleep. Researchers identified a structure in the circadian mRNA Period2 that alters the amplitude of circadian rhythms and disrupts sleep patterns, particularly during transitions between light and dark.
Scientists have developed a trivalent vaccine candidate that provides broad and long-lasting protection against COVID-19 infection by delivering the vaccine via the nose. The vaccine triggers a strong neutralizing antibody response and protects mucosal areas, preventing disease symptoms.
A new study found that a shorter radiation treatment course is just as effective as a longer schedule for patients with non-HPV-related locally advanced disease. Delivering fewer, but higher doses of radiation was associated with similar tumor control and late-term side effects.
A new AI method leverages causal relationships in genome regulation to efficiently identify optimal genetic perturbations for cellular reprogramming. The technique reduces experimental costs by prioritizing the most informative interventions, leading to faster convergence and more effective results.
Researchers found that using electronic prompts during appointment scheduling for seasonal flu and COVID-19 vaccines can identify willing participants for HPV and shingles vaccines. Only 30% of those booking for these vaccines were already vaccinated against HPV, presenting a significant opportunity for targeted campaigns.
A study using 29 low-cost instruments revealed PM2.5 values exceeded Indian national standards, associated with crop residue burning and secondary formation. The data will aid in addressing environmental impacts of air pollution.
Researchers from FAU's College of Engineering and Computer Science employ a computer-vision deep learning technique to analyze wall-bounded turbulent flows. They successfully identify the sources of extreme events in a data-driven manner, providing new insights into non-linear relationships in fluid dynamics simulations.
Research reveals increased sympathetic nerve activity and reduced exercise capacity in patients with heart failure resulting from anthracycline chemotherapy. Sympathetic neural overdrive is associated with skeletal myopathy and decreased cardiac function.