A study by Washington State University researchers found epigenetic alterations associated with elk treponeme-associated hoof disease, suggesting a systemic impact. The findings also suggest that the disease may be heritable, raising concerns about its transmission and susceptibility.
Scientists discovered that solid electrolyte interphase (SEI) layer behaves like a semiconductor, causing electron leakage and leading to inferior battery performance. Minimizing organic components in SEI enables longer-lasting batteries.
A new modeling method powered by interconnected processors removed human bias from the debate over dinosaurs' demise. The study suggests that the outpouring of climate-altering gases from the Deccan Traps alone could have been sufficient to trigger global extinction, consistent with volcanic eruptions contributing to the mass extinction.
A retrospective analysis of 37 heavily pretreated multiple myeloma patients found that intravenous immunoglobulin (IVIg) reduced the risk of severe infections by 90%. Patients with hypogammaglobulinemia experienced a higher rate of severe infections, and IVIg supplementation significantly mitigated this risk.
Researchers at Max Planck Institute for the Structure and Dynamics of Matter demonstrated that intense laser fields can probe electron dynamics in liquids. The team found that the mechanism of high-harmonic generation is unique to liquids, with the maximum photon energy independent of laser wavelength.
Research highlights the challenges of rural hospital-based maternity unit closures and transportation barriers, leading to delays in care and adverse outcomes. The study suggests that telehealth services can provide a solution to address these disparities in maternal health outcomes.
Researchers have developed a new semiconducting material called multielement ink that can be processed at low temperatures, paving the way for more sustainable semiconductor industry. The breakthrough enables faster and lower-energy production of semiconductors, which could significantly reduce carbon emissions.
Researchers have discovered a unique adhesin in Candida auris that enables it to stick to surfaces and cause disease. The study found that this adhesin, SCF1, is essential for colonization and virulence, suggesting a potential target for anti-fungal therapy.
Researchers tested five chemicals on zebrafish embryos and found that all caused impaired migration of bone-forming cells, leading to facial malformation. The study suggests a potential general mechanism underlying teratogenic chemicals and proposes using zebrafish as an alternative method for testing cross-species teratogens.
Researchers developed a high-resolution technique SBS-seq to characterize the complete sequence-range of sulfur binding domains, enabling a new nucleic acid detection platform. The technique employed tandem PT-modifications to improve binding affinity and extend the sequence-range of SBDs.
A recent study found that grandparent childcare does not significantly impact maternal mental health and wellbeing, nor does it reduce mother-child conflict. In fact, poor maternal wellbeing at age three was linked to poor child social and emotional outcomes at age seven.
Researchers have created the first-ever map of a single animal's early visual system, reconstructing it from the eyes to neurons in a tiny parasitic wasp. The study reveals complex behaviors such as flight in an insect with just 8,600 cells compared to the human brain's 171 billion.
A new study examines the pros and cons of advanced maternal age, finding that while older mothers face increased risks, they also have significant advantages due to their socioeconomic status. The research aims to untangle the truth about this complex issue by investigating how biomedical knowledge is produced and disseminated.
A large-scale study confirms that playing Tetris for fifteen minutes can prevent psychological trauma in mothers after a difficult birth. The therapeutic activity was found to interfere with memory consolidation of traumatic images, thereby preventing the development of post-traumatic stress symptoms linked to childbirth.
A UNIGE team investigated the destruction of neurons at different times of the day using fruit fly models and found that cellular stress was more deleterious to neurons at night. This suggests that the circadian clock exerts a protective effect on dopaminergic neurons against oxidative stress.
A team of researchers has uncovered a previously unknown compensatory mechanism found in liver disease. Giant cell clusters, formed by immune cells from the bone marrow, take over the filtration function of impaired Kupffer cells. This finding changes the way we think about the role of the immune system in liver fibrosis.
A gain-of-function HPY1 allele is identified as a key regulator of both photosynthetic capacity (source) and grain size/number (sink) in rice. This synergy enhances rice yield, leading to increased biomass and larger grains.
Researchers found a significant connection between biological particles and the formation of ice in Arctic clouds. The study's innovative approach revealed correlations with variables like snow cover and temperature, shedding light on the prevalence of fungal spores and their impact on climate models.
Recent research reveals that certain soil microorganisms persist and even thrive during drought periods, influencing ecosystem balance and plant growth. A novel method using water vapor measurement indicates that specific bacterial species become more active under simulated future climatic conditions.
A pharmacist-led diabetes control intervention was found to improve glycemic control and reduce the risk of complications among Hispanic adults with type 2 diabetes. The study, which included 931 participants, suggests that this type of intervention may be an effective strategy for improving health outcomes in this population.
Researchers have made significant progress in using immunotherapies prior to surgery, leading to better biomarkers and more effective combination therapies. This approach has shown promise in various cancer types, including lung cancer, triple-negative breast cancer, melanoma, and gastrointestinal cancers.
Researchers warn of risks associated with eating sushi and sashimi, especially for individuals with weak immune systems. The study highlights the importance of adopting a broad approach to combat the spread of antibiotic-resistant bacteria through animal and human health, food production, and environment.
New research published in Cognitive Research: Principles and Implications suggests that small amounts of surplus information can negatively impact decision-making. When presented with complex causal models, people's ability to make good choices deteriorates as they receive more information than necessary.
Malaria parasites have developed resistance to artemisinins, a critical treatment for non-severe cases, with devastating consequences. The study found that effectiveness declined by 2025% between 2016 and 2019, highlighting the urgent need for new treatments.
Researchers develop natural-based, low-carbon building materials by mimicking the composite adhesive secreted by sandcastle worms, which binds grains together. These materials exhibit good mechanical performance and can be constructed from various grains using oppositely charged bio-polymer adhesives.
Researchers at the University of Surrey have developed an electronic diagnostic test for bacteria and viruses, including SARS-CoV-2. The 'Electro-chemical LAMP' (eLAMP) test is affordable, sensitive, and can be performed at home or in a hospital lab.
A recent study by Ohio State University researchers found that saturated fats can interfere with the creation of new memories in aged brains. However, omega-3 fatty acids, particularly DHA, may help protect brain cells from fat-related inflammation. The study used cell cultures and brain tissue from aging mice to explore the effects of...
A new imaging agent, 68Ga-ABY-025, can predict early metabolic response to HER2-targeted treatment in HER2-positive metastatic breast cancer patients. Whole-body PET/CT enables quantification of HER2 expression and predicts metabolic response, potentially sparing patients from unnecessary side effects.
A new holographic 3D display system has been developed with a wider viewing angle of 73.4°, significantly improving over previously proposed systems. The system uses SLMs and liquid crystal grating to achieve this improvement.
Researchers at Columbia University found that when courtship is involved, dopamine-based error signals are suppressed and replaced by reward signals for performing well. This suggests a socially driven shift in the brain's self-evaluation system during courtship, potentially applicable to learning other behaviors.
Recent state-sponsored infrastructure projects in Angola and Mozambique have been linked to climate-related humanitarian disasters. Research by Ruy Blanes highlights the need for local consideration in planning, as neglect can lead to devastating consequences.
A study by the DZD found that losing abdominal fat can reverse prediabetes and reduce the risk of developing type 2 diabetes. Participants who achieved remission showed improved insulin sensitivity and reduced markers of kidney damage, while maintaining similar weight loss as non-responders.
A new quality improvement study shows a primary care intervention reduced the number of older adult patients at risk for hypoglycemia by almost 50%. The tool facilitated shared decision-making and improved patients' daily lives, leading to de-escalation of diabetes medications causing hypoglycemia in 20% of participants.
Researchers at Baylor College of Medicine developed a new compound called d16 that can reduce tumor growth and overcome therapeutic resistance in mutant p53-bearing cancers. The compound, which targets the DNA2 enzyme, shows promise as a potential combination therapy for difficult-to-treat cancers.
A new study suggests that hot flashes experienced during sleep may be an early indicator of women at higher risk of Alzheimer's disease. The study, which involved nearly 250 midlife women, found a greater number of sleep hot flashes to be associated with an increased likelihood of Alzheimer's.
The use of an animal rescue system – Hawk Data Pro – proved vital in detecting and controlling a potentially deadly rabies outbreak in Pune city, India. The system helped document an ongoing outbreak and direct awareness materials and mass dog vaccinations.
Current online trust mitigation efforts are focused on a single topic and geographic scale, leading to limited effectiveness. The 'glocal' phenomenon means distrust is spreading with diverse topics and local-global interests, making it challenging for organizations to address.
A study found that microplastic exposure negatively affected the survival, growth, and emergence of sediment-dwelling invertebrate larvae, but not their offspring. Ingestion of microplastics may inhibit food acquisition or nutrient assimilation in parentals, which can lead to negative impacts.
People with fewer financial resources have lower life expectancies due to factors like healthcare costs and economic inequality. Longer-term financial planning is associated with a lower risk of death, even after accounting for other factors.
A large US study found that increased fibre and carbohydrate from whole grains, fruit, and non-starchy vegetables is associated with less weight gain in midlife, while refined carbohydrates are linked to greater weight gain. Replacing refined carbs with whole grain equivalents results in less weight gain.
A new study suggests that physiologically assessed hot flashes may be associated with greater systemic inflammation, a risk factor for heart disease. Midlife women experiencing frequent hot flashes may require focused cardiovascular disease prevention efforts.
Researchers at NYU Grossman School of Medicine found that blocking the Notch signaling pathway in aging skeletal stem cells increases bone mass and restores lost bone-healing ability. The study used single-cell RNA sequencing to reveal that Notch signaling becomes abnormally active with age, shifting cells towards fatty degeneration.
A study of 77 wild Asian elephants found that individual differences in willingness and ability to problem-solve impact their success in accessing food. The most innovative elephants solved all three compartment types, demonstrating cognitive flexibility and potential implications for conservation management.
A recent study published in Human Reproduction found a doubling in the chances of pregnancy miscarrying or resulting in a stillbirth following a job loss. The researchers emphasize an association between job loss and increased probability of miscarriage or stillbirth, highlighting potential socioeconomic factors.
A new study found significant differences in cerebral blood flow and arterial transit time between women at different menopause stages and age-matched men. The researchers discovered distinct spatial distributions of these changes, with sex differences being more pronounced than any effect of menopause stage.
A new study found that faces against houseplant or bookcase backgrounds are perceived as more trustworthy and competent than those with other backgrounds. The research, published in PLOS ONE, suggests that videoconference users, particularly men, may benefit from using these background images to make a good impression.
Researchers identified two SARS-CoV-2 protein mutations linked to severe COVID-19 symptoms and increased inflammation. The mutations, known as KR, were found in patients with higher viral loads and more severe symptoms.
The James Webb Space Telescope detected no significant atmosphere around TRAPPIST-1 b, a planet in the habitable zone of its cool star. The study highlights the impact of stellar activity on observations of exoplanets, which can create 'ghost signals' that affect data interpretation.
A new study by UTA researchers found that vertebrate population declines are five times slower in conservation areas compared to those outside protected lands. Conservation areas help stabilize amphibian and bird populations, while also having a positive impact on reptiles in countries with good governance.
Liver cells become scarring when damaged by conditions like viral hepatitis or excessive drinking, leading to cirrhosis and liver failure. Reversing this process involves targeting the creation of scar tissue and addressing underlying causes, offering new hope for patients with liver fibrosis.
Research highlights personality traits and mental health problems as key causes of erectile dysfunction (ED), with biological components often overlooked. The study calls for better integration of psychological and biological treatments for ED, including couples therapy and diverse population research.
A team of researchers elucidated how hydrogen peroxide affects the degradation of a carbon-based catalyst named N-G/MOF. The study examined changes in the catalyst's elemental composition, major chemical bonds, crystal structure, and morphology under varying concentrations of hydrogen peroxide.
Researchers aim to develop programmable formal specification-based data stream processor and hardware monitor to enhance microchip security and prevent malfunctions. They will explore novel technologies for real-time monitoring of physical and biological systems, including signal patterns within computer chips.
A new study resolves a long-standing contradiction in brain function by revealing that familiar stimuli trigger brief neural spikes, known as visually evoked potentials (VEPs), which suppress activity. The findings advance understanding of visual recognition memory, enabling prioritization of attention.
Researchers found persistent inflammation in intestines of patients 20 years post-radiotherapy, even with targeted treatments. This could lead to chronic symptoms like tenesmus and frequent diarrhea.
Researchers have identified that ancient quakes occurred in shallow faults on the Puget Lowlands in western Washington, which could lead to another devastating event. The study used tree rings to pinpoint the dates of these quakes and found a link between them, suggesting regional hazard models may need to be updated.
A new study found that US K-12 students' science learning standards vary widely in their coverage of environmental issues, reflecting the states' dominant political ideology and major industries. The quality and depth of information on planetary health issues are greatly impacted by these factors.
Researchers from the Netherlands found that traditional swimming lessons in the country often discourage children from having fun in the pool. By adopting a teaching style based on self-determination theory, instructors can nurture autonomy, competence, and relatedness, leading to improved swimming skills and increased enjoyment. The s...
The IISc team developed a fully indigenous GaN power switch, comparable to state-of-the-art switches, with a switching time of about 50 nanoseconds. The device's performance is suitable for applications such as power converters for electric vehicles and laptops, as well as wireless communications.
Researchers identified dozens of genes implicated in neurodevelopmental disorders, which have similar effects on brain function. The study uses a new method to sort defective genes by their function, accelerating drug development for these disorders.