Researchers at University of Technology Sydney have successfully created personalized 'bio-inks' from patients' own stem cells, which are then used to 3D-print cardiac tissues to repair areas of dead tissue. This technology shows promise in treating heart failure and may reduce the need for expensive and traumatic heart transplants.
Researchers at Garvan Institute of Medical Research found that introducing bacteria to a tumor's microenvironment triggers an immune response, activating neutrophils to destroy tumors in animal models. This breakthrough therapy targets neutrophils to improve cancer treatment outcomes.
Researchers from Kumamoto University found that synchronizing ovulation and mating in
A recent study published in PNAS reveals that the protein TSKS plays a crucial role in eliminating sperm cytoplasm, enabling a streamlined structure necessary for successful fertilization. The findings suggest potential applications for diagnostic tests and male contraceptives.
A new device developed by quantum engineers can measure the spins in materials with high precision, breaking the current record of thousands of spins. This breakthrough enables researchers to study systems that were previously inaccessible, such as microscopic samples and two-dimensional materials.
A phase two trial found that exenatide significantly reduced brain pressure and monthly headaches in seven patients with Idiopathic Intercranial Hypertension (IIH). The study showed a rapid action of the drug, with results indicating significant reductions in brain pressure and headache days compared to the placebo arm.
A new technique involving a small flap in the peritoneum can reduce postoperative complications in prostate cancer surgery by allowing lymphatic fluid to escape and be absorbed. The study found that this technique significantly reduced the incidence of lymphocele, a common complication where lymphatic fluid collects in the pelvis.
The ProtecT trial found that active monitoring of prostate cancer has the same high survival rates after 15 years as radiotherapy or surgery. Men on active monitoring were more likely to see their cancer progress, but this didn't reduce their likelihood of survival.
A cross-disciplinary team developed a convolutional neural network to analyze microscopy images of chromosomes with cohesion defects. The algorithm achieved 73.1% accuracy in classifying new images, streamlining experiments with chromosome analysis.
A UK study reviewing over 90,000 vasectomies found that chronic scrotal pain occurs in just 0.2% of patients, while post-operative infection rates are around 1.6%. The study updates outdated figures and aims to encourage more men to undergo the procedure.
A study published by the European Association of Urology defines 'growers' and 'showers' as men whose penises increase in size by more than 56% when erect, compared to flaccid states. The researchers found that most men fell into a 'grey zone', with only 24% classified as growers and 25% as showers.
Domestic solar panel manufacturing in the US can reduce greenhouse gas emissions by 30% and energy consumption by 13% compared to international trading partners. By 2050, US-made solar panels will be more efficient, reducing carbon footprint by 33% and using 17% less energy.
A study of nearly 24,000 individuals reveals insurance status as a modifiable risk factor for racial and ethnic inequities in advanced cervical cancer diagnosis. Expanding access to care may mitigate these inequities.
A recent study published in JNCCN found that the lack of genomic research for people with African ancestry is hindering efforts to reduce disparities in prostate cancer outcomes. The researchers evaluated molecular genetic results for 113 Black South African men diagnosed with advanced prostate cancer, identifying 17 pathogenic and pot...
A team of scientists discovered a new genus and species of ancient gnat fossils in Mallorca, Spain, dating back to the early Middle Triassic period. The fossil, found near the harbor of Estellencs, shows how insects adapted to a post-apocalyptic world after a mass extinction event that wiped out over 80% of species.
Researchers have discovered unexpected similarities between stone tools used by monkeys and some of the earliest hominin stone artifacts. The findings suggest that accidental production of stone fragments during nut cracking may hold clues to the origin of intentional tool use in early humans.
Scientists have demonstrated a breakthrough in manipulating magnetic materials without using magnetic fields, paving the way for ultra-fast and energy-efficient memories. The researchers achieved sub-picosecond magnetization reversal in rare-earth-free spintronic structures, expanding the bandwidth of common devices.
A study found that telemedicine visits did not adversely affect the quality of care for patients with major depression, and even improved some aspects of care. The transition to virtual visits also led to increased adherence to measurement-based care practices.
A new study suggests that pregnant women who have dimmed lights and screens for three hours before sleep are less likely to develop gestational diabetes. Dim light exposure before bedtime may help regulate glucose levels, reducing the risk of this common pregnancy complication.
Researchers in Japan used a synchrotron to create gamma rays that revealed unusual fluctuations in the electrical charge of a strange metal alloy. The study provides insight into the inner machinery of these materials, which could inspire new forms of electronic matter and high-temperature superconductivity.
Researchers developed a new method combining pMINFLUX microscopy with graphene energy transfer, enabling axial precision of less than 3 angstroms. This allows for the study of molecular structures and dynamics at the nanoscale, fundamental for understanding cellular biomolecular reactions.
A new study found that Black patients with pulmonary fibrosis are significantly younger than their Hispanic and white counterparts, experiencing accelerated disease progression. Lifestyle and socioeconomic factors linked to environmental exposures may contribute to these disparities.
A team of microbiologists proposes using powerful microbial technologies to reduce global and local challenges leading to conflict, including food supply security and pollution. The authors advocate for deploying these technologies to address humanitarian crises and advance Sustainable Development Goals.
Peeter Laud's research aims to create a distributed identity system by removing single points of failure and improving privacy properties. He will explore how digital evidences can be issued privately using cryptographic technologies like zero-knowledge proofs.
A new study found that future incidents of simultaneous climate extremes will be exacerbated by human-driven climate change, with the strongest increases in tropical regions. Increasing concurrent temperature extremes will weaken tropical ecosystems' ability to act as carbon sinks, amplifying global climate change.
The γ-MnO2 dual-core pair-hole fiber enables the production of an all-fiber mode-locked laser with a pulse width of about 1 ps and a repetition frequency of about 600 MHz. This fabrication scheme offers good stability and is suitable for combining other novel materials with specialty fibers, expanding ultrafast optics and sensing appli...
Researchers found that phosphorus limitation decreases global and Chinese carbon sink strength by 7-16% by 2030s. The positive feedback between net primary productivity and soil decomposition amplifies this impact in China.
An international team of researchers has successfully read and assembled the whole genome of faba bean, a globally important protein source. The new genome reveals key genes for seed size and provides insights into improving drought and disease resistances, processing quality, and nutritional value.
A new study reveals that northern and southern resident orcas differ in their hunting behaviors, with males catching more salmon per hour than females. Southern resident males outperform females by 152%, highlighting a distinct pattern of foraging that may contribute to the population decline.
Researchers have improved Brillouin microscopy to acquire mechanical images of cells and tissues at speeds 50-100 times faster than existing methods. This innovation enables the investigation of cell behaviors in real-time, with potential applications in cancer diagnosis and embryonic tissue development.
Researchers suggest a four-part framework to identify animal viruses that may infect humans, focusing on viruses from repeat offender families and those with known human compatibility. By studying these viruses early, scientists can develop diagnostic tools and treatments, and be better prepared to combat future pandemics.
Researchers developed temporal compressive super-resolution microscopy (TCSRM) to overcome optical diffraction's spatial resolution restriction. TCSRM achieves high-speed imaging at 1200 frames per second with a spatial resolution of 100 nanometers, enabling observation of fast dynamics in fine structures.
A meta-analysis of 34 studies found a significant association between autism spectrum disorder (ASD) and increased risks of developing diabetes, dyslipidemia, and heart disease. Children with ASD were more likely to develop these metabolic complications, prompting clinicians to monitor them closely.
Researchers found that migratory birds can restore several parameters of their immune function during stopovers, not just to refuel. This discovery suggests that these short breaks are essential for the birds' overall health and immune system.
A survey of over 1000 patients found that two thirds prefer a urologist of their own gender, but in certain situations, both men and women choose a female doctor. Patients with painful conditions are more likely to opt for a female urologist.
A study of one family with monogenic diabetes reveals that insulin deficiency is the principal factor leading to a smaller pancreas. The Vanderbilt University Medical Center researchers discovered this through precise measurements of the pancreas taken from four family members.
A new international study reveals that global squid fisheries are operating largely in unregulated areas, with 86% of fishing efforts recorded between 2017-2020. This expansion poses significant challenges to fisheries sustainability and resource equity.
A study found that prenatal exposure to the anti-nausea drug Bendectin, containing dicyclomine, increased the risk of colorectal cancer in adult offspring. Incidence rates were three times higher among exposed children compared to those not exposed.
A recent study from Aarhus University reveals that B cells can be activated by antigens that only bind one receptor at a time, challenging the long-held model of immune recognition. This discovery holds promise for designing more effective vaccines and treating autoimmune diseases.
Researchers from Swansea University and Université Grenoble Alpes demonstrate the effectiveness of selenium nanoparticles in killing ovarian cancer cell models. The study reveals a novel biological mechanism underlying the anti-cancer effect, involving histone methylatransferases and epigenetic processes.
A new platform allows researchers to study cell-cell interactions in inflammatory neurological diseases like multiple sclerosis (MS). By identifying genes that control biologic processes, the team hopes to develop therapeutics to change disease-promoting cell behavior.
Children with Down syndrome are highly vulnerable to developing aggressive leukaemia due to a defect in the RUNX1 gene, which regulates blood cell formation. Researchers have identified a specific variant of the gene that promotes leukaemia development and discovered potential therapeutic approaches to correct this malfunction.
An analysis of European marine fish found temperature to be a key driver of large-scale spatial variation in fish assemblages. By 2050 and 2100, the study predicts the greatest community-level changes will occur at locations with greater warming, particularly further north.
The new technique allows for the production of a dozen different soft polymer material morphologies, including ribbons, nanoscale sheets, rods, and branched particles. By precisely controlling three sets of parameters during manufacturing, researchers can fine-tune the morphology of polymeric materials at the micro- and nano-scale.
Earth Map provides users with intuitive remote sensing data and enables a broader range of actors to take an active role in monitoring lands impacted by human activities. The tool aims to inform decision-makers about the current state of climate and resource management, driving meaningful policy changes and sustainable livelihoods.
Glaucoma researchers identify mitochondria as a key source of energy for optic nerve cells, and restoring balance can protect these cells from damage. The study suggests enhancing mitochondrial biogenesis may be a promising treatment strategy.
The February 2023 nTIDE report shows people with disabilities increasing their labor force participation rate to an all-time high of 40.2%, outperforming non-disabled peers in the labor market. The employment-to-population ratio also narrowed, reflecting gains made by people with disabilities since the pandemic.
Cambridge researchers observe Unio crassus mussels squirting water jets up to a meter away from the riverbed to increase the chances of their larvae attaching to specific host fishes. This behavior has never been seen in any other mussel species and may be crucial for the endangered species' survival.
A USC-led team of scientists identified the key gene Nr5a2, essential for opening up genome regions that enable neural crest cells to form tendons and salivary glands. Zebrafish and mice lacking this gene exhibited skeletal and tendon defects, as well as failed salivary gland development.
The International Research Network for Nuclear Astrophysics (IReNA) has partnered with the Ibero-American Network of Nuclear Astrophysics (IANNA) to enhance knowledge in nuclear astrophysics. The new collaboration will enable researchers from both networks to access cutting-edge technology and combine their expertise, resources, and ac...
A recent study highlights the perils of bacteria's secret antimicrobial resistance, which can be difficult to detect using traditional methods. Researchers are exploring new approaches, such as genetic analysis, to identify and prevent the spread of these resistant strains.
A study of 4.3 million patients found shorter primary care visits were associated with a higher likelihood of antibiotic overprescribing and co-prescribing opioids and benzodiazepines. Younger, publicly insured, Hispanic, and non-Hispanic Black patients had shorter visits, highlighting opportunities for operational improvements in visi...
Expanding Medicaid-benefit eligibility reduced Black-white disparities in preventable hospitalizations and emergency department visits by 10% or more. The study controlled for age, sex, and state variables to understand the effects of expansion on access to care.
Researchers discovered that jewel beetles have duplicated genes allowing them to see new colors, including ultraviolet and blue light. This evolution likely occurred after the loss of blue vision in beetle ancestors around 300 million years ago.
A new urine gene test can detect genetic mutations in urine that predict bladder cancer up to 12 years in advance of clinical symptoms. The test was trialled on over 50,000 participants and showed promising results, suggesting its potential for early detection and reduced unnecessary invasive procedures.
The Meta-Semi algorithm achieves competitive performance on challenging semi-supervised learning tasks, such as CIFAR-100 and STL-10, with only one additional hyper-parameter to tune. This approach naturally yields a meta-learning formulation where the correctly pseudo-labeled data has a similar distribution to labeled data.
Researchers at the University of Cincinnati developed an innovative breathing device called PEP Buddy, which improves symptoms of breathlessness, quality of life, and oxygen levels in people with COPD. The study found significant reductions in shortness of breath and improvements in quality of life among participants.
An international team of researchers has received $3 million to study how early gut development shapes children's health. They will collect tissue samples from diverse groups to understand the impact of environment, genetics, and other factors on gut development.
Researchers at University of Bonn discover a backup mechanism in immune cells that ensures efficient antiviral responses despite TBK1 enzyme mutations or complete loss. This mechanism relies on the stability of IKKepsilon protein, which compensates for TBK1 deficiency.
The study reveals that enzyme ATE1 enhances activity upon binding iron-sulfur clusters and is sensitive to oxygen, moderating the cell's response to oxidative stress. This discovery could lead to new therapeutic targets for diseases tied to chronic cellular stress.