Research from Lancaster University found that new caregivers during COVID-19 experienced a sharp decline in their own mental health, with the most significant impact occurring during national lockdowns. Existing carers also saw a decline in mental well-being, particularly during the third lockdown.
A decade-long analysis reveals that most clinical trials are never cited by the time they reach point-of-care, with less than one in two Phase III trials being cited across 9 out of 18 medical specialties. The study found that NIH funding correlates strongly with citation rates, with costs ranging from $48,086 to $874 per new citation.
Researchers demonstrate safety and effectiveness of DREADD-based strategy to suppress epileptic seizures in model monkeys. The treatment, deschloroclozapine (DCZ), can control widespread seizures within minutes without tissue damage or impairment.
A new study published in PLOS Global Public Health found that factors such as marriage status, age, and education are associated with pregnancy termination in 36 low- and middle-income countries. The study used data from over 1.2 million women aged 15-49 and found that married women, those over 30, and those with higher education were ...
The EU has launched an online treatment program called Prevent It to reduce child sexual abuse, providing a nine-week digital program with individual support. The program has shown promising results in reducing the risk of sexual exploitation and is now available in several languages.
Researchers discovered that glassy-winged sharpshooters use a 'superpropulsion' mechanism to launch droplets of pee at high speeds, conserving energy in the process. This innovative strategy helps the insect efficiently excrete its 99% water fluid waste.
A growing gap in NIH funding created an elite class of super principal investigators with persistent gaps in gender, ethnicity, and race. Researchers highlighted the critical need for reform to promote equity among NIH investigators.
A study published by Queen Mary University of London found that feeling supported at work reduces the risk of depression, anxiety, and burnout. Improving workplace aspects such as manager approachability, consistent information, and staffing levels can significantly protect mental wellbeing in healthcare professionals.
This special supplement from Annals of Family Medicine highlights the work of six HRSA-funded academic units focused on advancing health care equity and improving primary care practices. The articles cover topics such as workforce training, mental health care seeking, socioeconomic issues, and whole-person oriented healthcare.
Hollings researchers create small molecule that targets CD38 enzyme activity, stimulating proliferation of natural killer cells and enhancing anti-cancer activity. The compound has potential as an adjuvant therapy to boost effects of existing treatments and reduce resistance to monoclonal antibodies.
A review of evidence suggests that increased parental energy investment in young offspring may have facilitated the evolution of larger brains in some species. This is particularly true for warm-blooded species, which tend to invest more energy in their young through actions such as egg production and lactation.
A recent study found that bacterial co-infection in COVID-19 patients significantly increased the risk of death, intensive care unit admission, and mechanical ventilation. The study reviewed 13,781 COVID-19 inpatient encounters and identified laboratory trends associated with COVID-19 bacterial co-infection.
Research from Binghamton University highlights the importance of ants in forest regeneration, with over 95% of New York state forests relying on them to disperse seeds. Ants take seeds with fatty rewards back to their nests, protecting them from consumption by rodents and other organisms, promoting a mutually beneficial arrangement.
Researchers studied a Type 1a supernova in a faraway spiral galaxy, NGC 1566, to understand how certain chemical elements are emitted into the surrounding cosmos. The study confirms that ejecta doesn't escape the confines of the explosion, validating many assumptions about how complex entities work.
Researchers at Tohoku University analyzed samples from Japan's Hayabusa2 spacecraft and identified what they believe may be the oldest solids from the solar system. The grains were likely transported outward from the inner regions of the early solar system to their current location in the outer reaches.
A recent study found that sexting is associated with negative mental health outcomes, including depression, anxiety, and sleep problems. Participants who only sent sexts reported more mental health issues than others. The study highlights the need for further research into the correlations between sexting and mental health.
Researchers discovered that young snapping shrimp's upper claws can accelerate at speeds of up to 580,000m/s², surpassing their parents' abilities and producing powerful cavitation bubbles. The study, published in Journal of Experimental Biology, highlights the impressive mechanical capabilities of these tiny crustaceans.
A study analyzing over 800,000 tweets found that negative emotions expressed about geoengineering can easily fall into conspiracy theories. The researchers also discovered a strong link between geoengineering and the chemtrail conspiracy theory, with toxic tweets spilling over across regional boundaries.
A school-based wellness initiative led by MUSC's Boeing Center for Children's Wellness has been shown to reduce the average student BMI over time. The program, which targets policy, systems and environmental change, uses evidence-based strategies such as physical activity, nutrition and social-emotional wellness.
A team of researchers from Rensselaer Polytechnic Institute has developed a system to optimize TV ad scheduling, resulting in a 3-5% revenue increase for networks. The model combines mathematical programming and machine learning to assign ads to specific breaks and positions.
Researchers found interdecadal variability of solar radiation impacted strong Meiyu events, particularly in the Yangtze River. The study analyzed historical data and simulations, revealing a correlation between strong solar radiation and higher frequency of strong Meiyu events.
Researchers identify duplicated gene as cause of social deficits and seizures in autism type, finding that reducing PRRT2 levels can restore normal brain activity and behavior. This discovery could lead to novel therapies for neurodevelopmental disorders with brain over-activation.
A study by Princeton University researchers found that children are more likely to know an emotion label when they also know many related valenced words. Parents can support young children's learning of emotion labels by surrounding them with related words, such as
Scientists have discovered a previously unknown lineage of elephant bird that roamed the wet, forested landscapes of northeastern Madagascar, using ancient eggshell DNA. This breakthrough reveals new insights into the diversity of birds that once inhabited Earth and provides clues about their extinction.
Researchers found that breath analysis may be a valuable tool for COVID-19 diagnosis, but emerging variants pose challenges to overcome. The study's results warrant further evaluation to improve the use of breath analysis in patient care.
A UIC study published in Obesity links precarious work to increases in body mass index, particularly among Latino and Black women with lower education. The researchers analyzed 20 years of data from the National Longitudinal Survey of Youth and found a 2.18-point increase in BMI for every 1-point increase in precarious employment.
A study found that high-frequency spinal cord stimulation significantly reduced average pain levels by 76%, while improving motor function and sensation. The therapy's long-term safety and potential disease-modifying effects are promising, but further studies are needed to confirm the results.
Researchers have discovered that HIV creates reservoirs as early as the first days of infection, hiding and persisting during antiretroviral therapy. This finding is a major obstacle to curing HIV, but it also offers new opportunities for treatment development.
A survey of over 2,500 teens and young adults found that vaping nicotine and THC is associated with self-reported symptoms of depression and anxiety. Dual vapers were more likely to report addiction to nicotine and feel less depressed after starting vaping.
A new study found that polypharmacy, the concurrent use of multiple medications, increases the risk of adverse treatment outcomes in older adults with advanced cancer. Patients taking multiple medications had a 59% higher chance of stopping cancer treatment earlier than recommended.
Researchers developed an updated conservation metric, EDGE2, incorporating scientific uncertainty and status of related species. This approach identifies top-priority species for protection, preserving over 700 million years of evolutionary history, and allocates limited funds effectively.
Applying evolutionary principles to medicine inspires new ways of preventing and treating disease, including overcoming chemotherapy resistance and antibiotic resistance. Evolutionary-inspired strategies like 'anti-evolution' drugs and extinction therapy can tackle these global health threats.
A new machine learning model can predict city traffic activity in different zones of cities, enabling targeted responses from policymakers. Understanding people's mobility patterns is crucial for improving urban traffic flow, and the model provides insights into urban interactions.
Researchers found reduced brain oxygen levels in individuals with symptomatic COVID-19 illness, worse performance on cognitive tests, and increased psychiatric symptoms like depression and anxiety. Older women were more affected by the brain imaging outcomes.
A new study finds that bison herds in northern Yellowstone National Park are negatively impacting riparian plant communities, leading to biotic impoverishment and loss of ecosystem services. The effects of increased bison numbers are exacerbating climate change, shifting plant communities towards warmer and drier conditions.
Researchers from UPF's CaSEs research group have developed sustainable agricultural strategies using traditional small-scale rainfed agriculture for drought-tolerant crops like finger millet and sorghum. The study provides novel information on the intersection of traditional ecological knowledge and academic knowledge.
A liquid nitrogen spray developed by WSU researchers can remove almost all simulated moon dust from space suits with minimal damage. The technology uses the Leidenfrost Effect to clean spacesuits, performing better in vacuum environments than previous methods.
A study by Nagoya University researchers identified three intestinal bacteria - Collinsella, Ruminococcus, and Bifidobacterium - linked to dementia with Lewy bodies. These findings may help diagnose and treat the neurodegenerative disease, with potential therapeutic interventions targeting specific bacteria.
A study by Dr. Roman Lietz and Dr. Fergal Lenehan found that socially engaged Twitter users share similar values and motivations, including a commitment to human rights, tolerance, and understanding. Despite the harsh environment of social media, these individuals demonstrate surprising similarities in their perspectives on society.
A new study by PSE Healthy Energy and the University of California, Berkeley aims to investigate the relationship between exposure to air pollution, heat, and humidity with birth outcomes. The research will analyze disparities in local exposure across the region and develop targeted solutions to protect vulnerable populations.
Researchers have identified markers associated with an increased risk of metastasis in patients with metastatic pheochromocytoma, allowing for personalized clinical management. The study also identifies patients who could benefit from immunotherapy treatments, paving the way for potential new therapies.
Researchers identify 32 human monoclonal antibodies that can block SARS-CoV-2, SARS-CoV-1, and MERS-CoV coronaviruses. These antibodies target a vulnerable site on the viral spike protein, offering potential for broad protection against future pandemics.
Researchers found adult smokers with bipolar disorder and schizophrenia drink the most caffeine, while those with mental illness are at highest risk of negative health consequences. The study suggests mood, metabolism, and self-medication may explain use patterns among this population.
A new phylogenetic tree analysis by the University of Vienna has provided fresh insights into the evolutionary history of sharks and rays. The study found that the Late Jurassic shark Protospinax annectans was a highly evolved species, contrary to previous hypotheses about its position in the family tree.
Researchers employ defect engineering to improve nitrogen reduction and oxidation reactions, enhancing catalyst activity and stability. The study predicts future trends in defect engineering and nitrogen cycling.
Researchers developed intelligent metasurface robotics that provides real-time and full-context awareness of its operating indoor environment. This resolves limitations of conventional robotics, including limited field of view and sensitivity to skin color.
A new study by Brigham and Women's Hospital found that over 20% of patients at high risk of cardiovascular disease refused statin medications. Women were more likely than men to refuse statin therapy, with a 50% higher rate of never accepting the recommendation.
Scientists from the Institute of Botany discovered a widespread phenomenon called alcobiosis, where algae live inside fungal tissue and engage heavily in photosynthesis. The coexistence is common among corticioid basidiomycetes and is distinct from lichens.
Researchers from Hiroshima Shudo University and the University of Tokyo have successfully identified species of deep-sea brittle stars using a novel metabarcoding approach. This method analyzes environmental DNA released from marine invertebrates, enabling efficient and cost-effective monitoring of biodiversity.
Researchers identified microglia as key players in chemo brain inflammation, suggesting a potential target for treatment. In a mouse study, deleting microglia restored memory and lowered brain inflammation after paclitaxel treatment.
Researchers developed a new method for removing bisphenol pollutants and lignin derivatives using activated peroxymonosulfate and photothermal technology. The material, C-defects/C-O band-modified ultrathin porous carbon nitride, has shown faster reaction rates and improved oxidizing ability compared to conventional materials.
A new review paper from Mayo Clinic outlines how obesity impacts common tests used to diagnose heart disease, such as ECG, CT scan, MRI, and echocardiogram. The study highlights the need for alternative approaches to prevent weight gain in patients with heart disease.
The study combines osseointegration, TMR, and pattern-recognition control to operate a fully powered bionic leg prosthesis, aiming to restore intuitive control and comfort for those with lower-limb amputations. The device has the potential to provide unprecedented control and comfort for users.
Scientists at Universitat Autonoma de Barcelona have created spherical nanoparticles inspired by amyloid proteins that bind to the SARS-CoV2 spike protein with high affinity, preventing cell infection. The biocompatible and stable nanostructures also show great potency in blocking viral particles.
Researchers have created a simple and inexpensive method to disinfect drinking water using silver sulfide quantum dots encased in a peptide coat. When exposed to near-infrared light, these nanoparticles kill bacteria with high efficiency, making them a promising alternative to traditional methods.
Researchers develop innovative strategy to fabricate monolithically integrated micro-supercapacitors with high areal capacitance, volumetric capacitance, and stable performance. The devices achieve record areal output voltage and high systemic performance for powering miniaturized electronics.
A team from TU Wien has developed a method to cool several particles simultaneously by adapting the spatial structure of a laser beam to particle motion. The technique uses far-field wavefront shaping to optimize cooling and can be achieved without knowing the exact location or movement of the particles.
A new study finds that a combination of chemotherapy drugs performs better than BCG in preventing high-grade cancer recurrence in patients with non-muscle invasive bladder cancer. This alternative treatment has shown excellent safety and efficacy outcomes, providing a viable option for patients facing a shortage of standard care treatm...
Researchers at Johns Hopkins University are developing 'organoid intelligence' using human brain cells, which could exponentially expand computing capabilities and solve energy consumption issues. The technology has the potential to revolutionize drug testing research for neurodevelopmental disorders and neurodegeneration.
Excessive vitellogenin accumulation impairs lysosomal function in germline tissues, leading to reproductive arrest and oocyte quality maintenance. Improvement of lysosomal function is proposed as a potential approach for mid-life intervention in maintaining reproductive health.