Researchers at CityU and HKUMed developed genetically modified human neural stem cells that promote neural circuit reconstruction, reduce glial scar accumulation, and enhance axon outgrowth. The therapy demonstrates potential for treating severe spinal cord injuries with functional recovery.
A team of researchers led by Professor Aydogan Ozcan has developed methods for designing all-optical universal linear processors of spatially incoherent light. These processors use successive diffraction of light to perform arbitrary linear transformations without external digital computing power, enabling fast and energy-efficient com...
Gallium oxide-based flash memory device demonstrates high performance and stability in extreme temperatures and radiation, retaining data for over 80 minutes. The team aims to improve device properties through further material quality and design advancements.
A new study published in Neurology found that only a small percentage of older adults with early Alzheimer's disease meet the eligibility criteria to receive new monoclonal antibody treatments. The study estimates that around 8% of people with mild cognitive impairment or mild dementia would be eligible for treatment.
Researchers from Kyushu University discovered intentional cranial modification among the Hirota people on Tanegashima island, characterized by a flattened back of the skull. The practice, which predates written history, was likely used to signify group affiliation and preserve social status.
Researchers at University of Queensland discovered platelets secrete a protein that rejuvenates neurons in aged mice, similar to exercise. This finding has significant implications for developing drug interventions to promote neurogenesis and enhance cognition.
A new study reveals that Ötzi had a Mediterranean-European skin tone and little to no Eastern European ancestry. His hair was likely sparse, with a predisposition to baldness. The research team used advanced sequencing technology to analyze Ötzi's genome, which has more Anatolian farmer ancestry than any of his European contemporaries.
Researchers found that children and adolescents exposed to the 1959-61 Chinese famine in utero or under age 2 are at double the risk of developing non-communicable diseases. The study, published in PLOS Global Public Health, examined the long-term health effects of early exposure to famine on later life.
Royal colleges have received £9m in payments from drug and medical device companies since 2015 but often don't disclose these payments publicly. The Academy of Medical Royal Colleges should coordinate standardised disclosure, increasing trust and informed discussion about payment governance.
A new study found that exposure to groups with dual social identities improves intergroup attitudes, especially when individuals identify strongly with both parts of their identity. This suggests that embracing both identities can be beneficial for minorities in terms of intergroup relations.
A team of international researchers have successfully conditioned red foxes to avoid native prey by associating it with nauseous chemicals. The study, published in Conservation Science and Practice, used levamisole to induce nausea and vomiting in the predators. By hiding the taste and smell of the chemical, the researchers were able t...
The August issue of CHEST journal features a new clinical practice guideline for managing patients with neuromuscular weakness and a multisociety evidence review on the effect of race and ethnicity on pulmonary function testing interpretation. This is complemented by other research and reviews covering various aspects of chest medicine.
A global research team found that extreme heat exposure and prior infection from a protozoan pathogen can severely negatively impact solitary bees' thermal physiology and behavior. The study showed that healthy bees can tolerate high temperatures, but infected ones are less tolerant, affecting their ability to forage and pollinate crops.
The University of Arizona Health Sciences has been awarded a National Institutes of Health training program grant worth $750,000. This funding will continue to support master's students pursuing degrees in environmental and occupational health in the Industrial Hygiene Program.
The recovery of gray wolf populations in the United States has been broadly successful over the past 30 years, with many regions now sporting robust populations. However, these growing populations face significant threats, including fragmented habitats, barriers to dispersal, and increased encounters with humans, pets, and livestock.
A recent study published in The Lancet found that taking levonorgestrel emergency contraceptive pills with an anti-inflammatory medication called piroxicam significantly prevents more pregnancies compared to taking levonorgestrel alone. The co-treatment increased the pill's efficacy by up to 32%.
Researchers found human metabolites, pharmaceuticals, illicit drugs, and sunscreens in stream water, altering chemical and microbial fingerprint. Human recreation also stirred up sediments, raising metal concentrations and potentially affecting wildlife.
A novel CRISPR-based gene-editing treatment, EBT-001, effectively removes SIV from the genomes of non-human primates without off-target effects. The study's findings support the development of a cure for HIV/AIDS in humans and pave the way for ongoing clinical trials.
Researchers at Michigan Medicine have discovered a potential treatment for diffuse midline glioma, a type of childhood brain tumor with no effective treatments. The compound ONC201 nearly doubled survival rates in patients with the disease, and the underlying mechanism behind its success has been explained.
The University of Missouri is using a $1 million grant to develop an Industry 4.0 lab, providing engineering students with hands-on learning experiences in the latest industrial revolution's technology-centered job market. The lab will integrate skills at a higher level and keep students at the state-of-the-art level for industry.
Scientists at the University of Vienna have developed a new method to excite shorter and faster spin waves, a crucial step towards magnon-based computing. This breakthrough could lead to the creation of more efficient computer systems with reduced power consumption.
Researchers at Monash University have created a new method to reprogram human cells, called transient-naive-treatment (TNT) reprogramming, which reduces the differences between induced pluripotent stem (iPS) cells and embryonic stem cells. This breakthrough has significant implications for biomedical and therapeutic uses.
A systematic review by the University of Adelaide found combining pyrethroid insecticide with chlorfenapyr improves its effectiveness in treating malaria-preventing mosquito nets. The WHO has updated its guidelines to include these new recommendations.
Scientists have designed catalyst-coated lampshades that transform indoor air pollutants into harmless compounds using waste heat from lamps. The technology targets volatile organic compounds (VOCs), which account for most indoor airborne pollutants, and has been shown to work with halogen and incandescent light bulbs.
A new study by Ben-Gurion University researchers measures effort in football teams, finding that peer effort positively affects individual effort. Teammates' social connections also contribute to positive effects. The findings suggest that managers should consider workers' compensation based on effort, not just performance.
Chronic disease medications impair the body's ability to regulate core temperature, increasing the risk of heat-related illness in elderly patients. Exercise and improved fitness levels can help mitigate these effects, but bodily impairments from chemotherapy and medications may limit exercise capacity.
Recent studies have identified molecular inflammatory mechanisms that trigger the growth and transformation of progenitor cells into cancer stem cells, a key step in liver cancer development. Maintaining progenitor cell compartment integrity could be an attractive therapeutic strategy, while targeting IL-17 production may eradicate CSC...
A ban on personalized ads significantly reduces the number of available apps and updates, according to a TUM study. The findings can help policymakers and companies define their business models and adapt to regulations.
The new microscope uses structured illumination and optical fibers to achieve fast super-resolution imaging over a wide field of view, enabling the study of individual cell responses to various drugs. The system can image multiple cells simultaneously with high resolution, providing statistical information about cell response.
Scientists have created iron oxide nanoparticles called 'smart rust' that can remove a range of contaminants from water, including oil, nano- and microplastics, and estrogen hormones. The particles are magnetic and can be easily removed with a magnet, making them a promising tool for improving water treatment.
A recent study found that despite their high resilience levels, nurses considered leaving nursing at a higher rate during the COVID-19 pandemic. The study also showed that job satisfaction and work demands played significant roles in shaping intentions to leave nursing.
A study by Florida Atlantic University found that nearly all wristbands (95%) are contaminated with harmful bacteria, including E. coli and staphylococcus. The study suggests using metal types like gold and silver, which had little to no bacteria, and recommends regular sanitizing of wristbands, especially after gym activities.
A team of scientists has discovered extremely rare 160-million-year-old sea spider fossils in Southern France that are closely related to living species, providing new insights into their evolution. The findings suggest that the diversity of sea spiders had already started to form by the Jurassic period.
Glutamine metabolism plays a crucial role in cancer cell growth and survival, with its inhibition shown to block cancer cell growth in vivo and in vitro. A recent editorial paper suggests that glutamine dysregulation may also impact the tumor microenvironment, potentially leading to increased oxidative stress and cancer cell death.
A new study finds that people who adhere to a Mediterranean lifestyle have a lower risk of all-cause and cancer mortality. The study, led by La Universidad Autónoma de Madrid and Harvard T.H. Chan School of Public Health, analyzed data from 110,799 participants and found an inverse association between adherence to the Mediterranean lif...
Researchers propose a spatiotemporal hemodynamic monitoring technique using skin-like microfiber Bragg grating group for real-time monitoring of blood pressure, heart rate, peripheral resistance, and vascular elasticity. The device can detect subtle physiological signals and presents the dynamics of the systemic cardiovascular system.
A study of over 20,000 first-time parkrun participants in Scotland found that returning runners were more likely to be male, older, and faster. The event's proximity to freshwater and woodland also played a significant role in retention rates.
A systematic review and meta-analysis found a significant association between paternal depression and subsequent offspring depression. The study included over 7 million father-child dyads and suggests that mental health interventions can benefit the entire family.
UCI scientists discover that deeper Arctic snowpack is thawing ancient permafrost reserves, leading to increased greenhouse gas emissions. This process can accelerate emissions even if human-caused climate change is stopped.
Researchers from four countries sequenced genomes of 100 infants with unexplained seizures to better understand the potential strengths of early genome sequencing for infantile epilepsy. The study found that 43% received a diagnosis within weeks, and this impacted prognosis in nearly 90% of cases.
Brazilian researchers discovered an enzyme that can replace traditional catalysts in the production of aviation biokerosene, increasing renewable biofuel output. The enzyme, OleTP RN, promotes deoxygenation and is selective for different sizes and types of carbon chain.
A new study from the University of Colorado at Boulder has developed an economical approach for producing green hydrogen, a precursor to liquid fuels. The method uses heat generated by solar rays to split molecules of water and carbon dioxide into hydrogen and carbon monoxide, which can be converted into fuels like gasoline and diesel.
Women with low-risk breast cancer aged 55 or older can be effectively treated without radiation after surgery, according to new research published in The New England Journal of Medicine. A total of 2.3% of patients experienced recurrence of cancer in the breast five years post-surgery.
Researchers developed a novel method using Google Trends to assess player popularity and demonstrated its improvement in predicting market value. The method involves calculating six indicators of popularity that can be compared among players, improving accuracy when incorporated with other factors.
Researchers identify Noelin proteins as crucial for supporting synapse function in the brain and retina, providing insight into processes like learning and memory. The study also highlights the development of blinding conditions like glaucoma.
A case series shows that pig-to-human xenotransplant can provide normal graft function in a deceased human with chronic kidney disease. Future studies are needed to determine long-term xenograft kidney function and its potential as a bridge or destination therapy for end-stage kidney disease.
Researchers have discovered a possible link between mitochondrial function and schizophrenia, highlighting impaired energy production as a key factor in its development. Mitochondrial dysregulation can cause psychiatric symptoms and disorders, and its effects are seen not only in the brain but also in other cells, such as kidney cells.
Researchers used tower-based platform data to show that wind waves can increase wind stress, while swells reduce it. This study highlights the need for numerical models to consider both swell and wind wave effects on wind stress.
Scientists have demonstrated techniques to fabricate layered semiconductors with suitable bandgap and band structure, offering a new class of materials in photoelectronic applications. Heterogeneous integration of TMDs and traditional semiconductors enables the exploration of next-generation electronic and optoelectronic devices.
Despite increased problem behaviors like stranger aggression and training problems, shelter dog owners reported high satisfaction rates of 94% due to improved behavior over time. Owners also noted a decrease in separation-related behaviors as their dogs became more assured of return home.
The American Society for Biochemistry and Molecular Biology named 2024 award winners, Tamás Balla and Margaret Phillips, who made significant contributions to biochemistry and molecular biology. The recipients will give talks at the society’s annual meeting in March.
A new study reveals that corals use the mTOR signal path to incorporate nutrients from their dinoflagellate symbionts. This regulation is crucial for the health of corals and the entire coral reef ecosystem, which relies on these symbiotic partnerships for survival.
A new technique converts kale waste into phytochemicals for use in health and personal care products, preserving potency and using non-toxic solvents. The method reduces energy consumption and emissions, making it attractive for industry adoption and supporting a circular economy.
Researchers have identified 21 key chemical compounds that make pandemic-era sourdoughs so uniquely sour. These compounds include salt, acetic acid, and lactic acid, which are produced during fermentation and contribute to the bread's distinctive taste and smell.
A systematic review and meta-analysis found that dual active ingredient insecticide-treated nets are effective in preventing malaria. The study showed that these nets can control the spread of the disease when traditional pyrethroid-based nets become less effective due to resistance.
A new study led by Brown University researchers provides unprecedented insights into the forces influencing Arctic sea ice motion. The analysis reveals how local tidal currents affect sea ice movement and highlights the crucial role of the seafloor in causing abrupt changes.
Researchers at Tokyo Institute of Technology have developed a novel ferroelectric semiconductor memory device with a 100 nm channel length, enabling high-density storage and seamless integration with existing semiconductor technologies. The device exhibits typical resistive switching, high on/off ratio, large memory window, and good re...
Researchers have discovered a new scar type, reciprocal pairs, in HR-deficient cancers that create specific chromosomal changes. These findings may lead to new approaches in treating these types of cancers by blocking backup repair mechanisms.
The study of Ötzi's genome reveals surprisingly high levels of Anatolian Farmer ancestry, indicating a genetically isolated Alpine population. The findings also suggest that Ötzi had dark skin, dark eyes, and male pattern baldness, contradicting previous reconstructions.
A new study by University of East Anglia reveals ChatGPT's systematic left-wing bias, favoring Democrats in the US and Labour Party in the UK. The platform's responses also lean towards President Lula da Silva of Brazil's Workers' Party.