A comprehensive review of antidepressant use in chronic pain found that some classes were effective in treating certain conditions, while others showed unclear or unknown benefits. Serotonin-norepinephrine reuptake inhibitors (SNRIs) like duloxetine demonstrated efficacy for various pain conditions.
Researchers developed BirdFlow, a predictive model that utilizes eBird data and machine learning to forecast migratory patterns. The model was tested on 11 species of North American birds and found to outperform other models in tracking migration flows.
A 20-year study reveals that recent advances in surgical and clinical care have significantly reduced brain injuries in babies with congenital heart disease. Infants who received higher postoperative blood pressure had a 20% lower risk of brain injury compared to those in earlier stages.
Electrical tuning of passive radiative cooling enables temperature regulation at ambient conditions, reducing energy consumption and pollution. The technology has potential applications in building insulation, clothing, and wallpaper.
Researchers found that some antidepressant classes were effective in treating specific pain conditions, while others showed no benefits or unknown effects. The review of 26 systematic reviews involving over 25,000 participants suggests a more nuanced approach to prescribing antidepressants for chronic pain management is needed.
A new study analyzed 3,452 dogs with cancer to determine median ages of diagnosis based on characteristics such as weight, breed, and sex. The findings suggest that giant breeds, males, and purebred dogs tend to receive a cancer diagnosis at relatively younger ages.
A Tufts-led team discovered a brain region marker that indicates vulnerability to developing post-traumatic stress disorder (PTSD). The study found heightened amygdala activation in response to neutral facial expressions, suggesting an acquired characteristic of PTSD. This finding may inform early intervention strategies for individual...
A new study published in Cell Reports Medicine identifies four pan-cancer molecular subtypes of metastasis, each with distinct transcriptional programs and potential therapeutic targets. The research provides valuable insights for personalized treatments of metastatic cancer.
A team of researchers from Harvard and MGH developed a soft robotic wearable capable of significantly assisting upper arm and shoulder movement in people with ALS. The device improved range of motion, reduced muscle fatigue, and increased performance of tasks like holding or reaching for objects.
Princeton researchers have achieved a major breakthrough by microscopically studying molecular gases at a level never before achieved. The team cooled molecules to ultracold temperatures, observed individual molecules with high spatial resolution, and detected subtle quantum correlations, opening up new avenues for many-body physics re...
Scientists from the University of Vienna found that grid cells in the brain play a crucial role in detecting movements of people around us. This mechanism may help explain disorientation in dementia patients. The study suggests that grid cells create a mental map of our surroundings, including the movements of others.
Researchers found solid scientific evidence that Vikings transported animals, including a horse and dog, across the North Sea to Britain. The analysis of human and animal remains from the Heath Wood cremation cemetery revealed that these animals originated from Scandinavia.
A new study from the University of Portsmouth reveals that 'war tourism' has evolved into online activities such as countering misinformation and raising awareness for Ukrainian refugees. Researchers analyzed data from the Subreddit forum 'volunteers for Ukraine', which had over 44,500 members just two weeks after Russia's invasion.
Researchers identified HCirV-1 in a patient with unexplained chronic hepatitis, demonstrating its role in liver damage. After treatment, the patient's liver enzymes returned to normal levels, indicating the end of hepatic cytolysis.
A study at the University of Birmingham found that women can recall details of sexual assault with accuracy, regardless of moderate alcohol intake. The research challenged courtroom perceptions of intoxicated women as unreliable witnesses.
A multilayered fluidic system inspired by squid skin can optimize the wavelength, intensity, and dispersion of light reaching building interiors. This could lead to significant savings on heating, cooling, and lighting energy costs, with annual reductions of up to 50%.
The Geriatric Fracture Program at Cedars-Sinai Medical Center has been shown to reduce hospital stays by 2.12 days and lower hospital-related costs by $5,316 for patients aged 65 and older. The program's comprehensive care approach, including bone strength assessments and fall prevention strategies, is effective in improving outcomes.
The UK comic Beano promotes unhealthy food brands through quizzes and games on its website, raising concerns among health experts. The company collects data on children's consumption preferences, which is sold to companies, contributing to the problem.
A new smart contact lens has been developed to diagnose and treat glaucoma by monitoring intraocular pressure in real-time and releasing the appropriate amount of medication. The lens, created by a POSTECH research team, uses a flexible drug delivery system and wireless power and communication system.
Researchers at the University of South Australia are developing new biomarkers to improve melanoma detection and avoid delayed treatment. The current markers used in clinical practice are not always sensitive or specific, leading to fatal consequences if cancerous cells are missed.
The study highlights technological innovations to accelerate green transformation of textiles, including sustainable materials, manufacturing technologies, and recycling methods. These developments aim to reduce greenhouse gas emissions and water consumption, minimizing environmental impacts.
A new study found that 76% of global insect species are not adequately covered by protected areas. This underrepresentation is particularly concerning for critically endangered insects, with some species having no overlap with protected areas at all.
A new report by the University of Portsmouth found that UK coastal city residents face infrastructure challenges and accessibility barriers when trying to reduce their single-use plastic waste. Despite being concerned about plastic use, consumer behavior often contradicts these beliefs.
Researchers found that klotho has anti-inflammatory and neuroprotective effects on cultured glial cells, reversing increased secretion of pro-inflammatory cytokines. The study supports klotho's therapeutic potential in pathological processes with a neuroinflammatory component.
A study found that stock photography sites have limited representation of diverse populations, particularly people with darker skin tones and lower socioeconomic status. This limitation makes it challenging for organizations to develop effective communication tools to reach these groups.
Researchers found that Black children experienced more childhood adversity than White children, leading to differential changes in brain regions linked to psychiatric disease. The study suggests that structural racism may play a significant role in these differences.
A 550-million-year-old fossil of Dickinsonia was discovered in India, but it turned out to be a beehive. The correction puts the geologic and life history of India back into contention, with the rocks potentially being one billion years old.
A large study published in JACC: Heart Failure found that social isolation and loneliness are associated with higher rates of heart failure. However, feelings of loneliness were found to be a stronger predictor of heart failure risk than objective social isolation. The study suggests that effective tools for screening social isolation ...
A new approach to deep reinforcement learning demonstrates ability to stabilize large datasets used in AI models, which may lead to uncovering ways to arrest cancer development. The method has been successful in designing and refining existing therapies, with the next step being to use live cells.
Women who experience five major pregnancy complications face an increased risk of ischemic heart disease up to 46 years after delivery. The study found that all major adverse pregnancy outcomes should be recognized as lifelong risk factors for heart disease.
Researchers developed a novel CRISPR system to detect small amounts of cancer-related molecules in exosomes in plasma, effectively distinguishing between malignant and benign samples. The method has the potential to make cancer diagnosis and monitoring quicker and easier by analyzing blood samples.
A new optogenetic tool, OPN4-mGluR1, allows researchers to modulate mGluR1 signalling in the cerebellum using light. This enables the study of synaptic plasticity and its role in motor learning, offering new possibilities for understanding cerebellar-associated diseases.
A new analysis of NETosis from Dompé farmaceutici puts a spotlight on neutrophils in carcinogenesis. Neutrophils' behavior is modulated by extracellular vesicles and interleukin-8, leading to tumor progression and drug resistance. Targeting IL-8 and EVs may lead to novel drugs to regulate neutrophil biology.
Researchers at Iowa State University have developed a new procedure to improve eyewitness lineup accuracy and detect suspect guilt or innocence. The 'rule out' procedure adds confidence questions to standard lineups, allowing witnesses to provide more valuable information about their decision.
A new analysis found that human ignitions started 76% of the wildfires that destroyed structures in Western states, leading to increased structure losses. The study suggests that policymakers can lessen the risks of wildfire damage by addressing human-related ignitions and promoting fire-resistant building materials.
A team of biologists from the University of Amsterdam found that water pores in leaves are part of a plant's defence system against pathogenic micro-organisms. The discovery provides insight into how plants defend themselves against bacterial diseases, and may help make agricultural crops more resilient.
OmniVis, a pathogen detection company, has received $100,000 from the Purdue Ag-Celerator fund to establish a field pilot for its hand-held devices. The funding aims to test the devices in real-world settings and make connections with the agricultural community.
Astronomers have uncovered a rare binary star system that has the right conditions to trigger a kilonova, an ultra-powerful explosion created by colliding neutron stars. The system, CPD-29 2176, is one of only about 10 such systems thought to exist in the Milky Way Galaxy.
A team of researchers has developed an amplification technique to study a parity-violating interaction between spins mediated by a hypothetical Z' boson. The setup, called SAPPHIRE, uses polarized rubidium and xenon atoms to increase sensitivity five orders of magnitude, setting new constraints on the strength of this interaction.
A recent study published in Science Advances found that individuals with similar ideologies have more similar neural fingerprints of political words and process new information in a polarized way. The researchers used a range of methods, including fMRI and representation similarity analysis, to explore how the brains of people who iden...
Researchers at MIT have observed a rare resonance in colliding ultracold molecules for the first time, shedding light on the forces that drive molecules to chemically react. The discovery could lead to new ways to steer and control certain chemical reactions using magnetic fields.
A recent study found that China's cleaner heating policies in northern cities, including Beijing and Tianjin, reduced premature deaths from air pollution by 23,000 in 2021 compared to 2015. The stricter policies led to a significant decrease in fine particulate matter (PM2.5) concentrations.
A Rutgers researcher has analyzed data from Mexico's Ministry of Health to identify dengue fever hotspots, highlighting areas where severe outbreaks occur. The study found that lower socioeconomic status increases risk of dengue fever and that DENV-2 is the deadliest serotype.
Researchers at Kessler Foundation are conducting a double-blind randomized clinical trial to evaluate the impact of their strategy-based cognitive training program on new learning and memory in individuals with multiple sclerosis. The study aims to assess the efficacy of this protocol, which is based on the KF-STEM protocol.
A large cohort study found that vitamin D supplementation is associated with a reduced risk of suicide attempts among US veterans. The study highlights the importance of vitamin D levels and supplementation in preventing suicidal behaviors, particularly among Black veterans and those with pre-existing low vitamin D.
Embry-Riddle astronomers report a rare binary star system with an uncommon circular orbit, formed when a supernova fizzled out without the usual bang. The discovery sheds light on the origins of the universe and the formation of heavy elements.
Researchers discover intrinsic faradaic layer on semiconductor surface exhibits bipolarity under illumination, serving as electron and hole transfer mediators in photocatalysis and photoelectrocatalysis. A new descriptor for solid surface structure is introduced, simplifying the understanding of complex interactions.
Researchers found increased rates of pregnancy-associated deaths in the US from 2018 to 2020, with no significant decline. The pandemic contributed to these changes, with rates rising due to various causes including drugs, homicide, and suicide.
A team of researchers has proposed a novel method for multi-label classification that enables continual learning from big data. The approach combines clustering and Bayesian methods to achieve high classification performance and adaptability in the face of new data.
A study of nearly 2 million Tweets in London and San Francisco identified specific events and locations associated with different emotions. The analysis showed that certain locations, such as hotels and restaurants, were linked to higher levels of joy, while train stations and transportation sites were linked to disgust.
A study by NYU researchers found that music excerpts can accurately predict listeners' preferences for entire songs, regardless of clip length. The results suggest that the general vibe of a song is more important than its individual notes in evoking emotions in listeners.
Researchers found that while some antidepressants are effective for certain pain conditions, most are either ineffective or the evidence is inconclusive. A more nuanced approach is needed when prescribing antidepressants for pain, say experts.
Numerous studies prove that multimodal enrichment enhances learning outcomes through brain region activation and computer algorithms. Researchers hope this understanding will lead to optimal learning strategies in the future.
Scientists have created a small, portable device that can extract and pretreat bacterial DNA using voice commands, making it easier and safer for researchers to handle potentially infectious samples. The device has shown promise in extracting DNA from Salmonella Typhimurium with an efficiency of 70% in under a minute.
A study published in Women and Birth found that seeing the same midwives throughout the perinatal period makes a substantial difference to a woman's experience of care. The continuity of care model improves trust, advocacy, access, and consistency of care for high-risk mothers, reducing anxiety and stress.
The study examines the impact of climate change and economic sustainability on drinking water management strategies. The integrated assessment framework assesses factors such as water quality, environmental changes, and potential costs to determine performance data and benchmarking.
A $1.1 million Department of Defense grant supports Augusta University research linking prostate cancer and cardiovascular diseases. Dr. Avirup Guha's research aims to investigate the aging process, exploring the role of nicotinamide adenine dinucleotide in this connection.
Researchers at KTH Royal Institute of Technology have developed a process to unlock soluble ferulic acid-rich dietary fibers from corn bran, a low-value sidestream. The extracted antioxidants can prevent cell oxidation and improve gut health by delivering hydrogels that counteract oxidative stress.
Researchers at Korea Research Institute of Chemical Technology (KRICT) have developed biodegradable paper straws that outperform conventional straws, maintaining their integrity in cold and hot drinks. The new straws lose weight but decompose completely within 120 days, unlike regular plastic straws and corn plastic straws.
A systematic review and meta-analysis found that MRI-based surveillance after surgical treatment can detect clinically occult local recurrences, potentially improving patient outcomes. The study included 19 studies and showed a significant association between high-intensity surveillance and the detection of local recurrences.