Researchers analyzed over 500,000 patient records and found that patients diagnosed at age 70 were nearly twice as likely to be passed over for post-surgical radiation therapy. This significant gap in treatment recommendations suggests that cognitive heuristics play a major role in physician decision-making.
A new antimicrobial suture material has been developed to reduce infection rates and improve post-operative monitoring. The material, which combines iodine and nanoparticles, can be used for internal stitches and mesh implants, providing a promising alternative to existing products.
A team of experts discovered a recruitment mechanism for cancer-associated fibroblasts in lung adenocarcinoma, the most frequent type of lung cancer. This finding could lead to the development of new treatments targeting these cells' migratory advantage, which contributes to tumor progression and metastasis.
Researchers have identified a distinct latent reservoir of HIV-infected CD4+ T cells in the central nervous system (CNS), separate from the latent reservoir in blood and lymph tissue. This finding highlights a new challenge in creating a cure for HIV, as any curative therapy would need to activate both dormant reservoirs.
A new study at Cornell University introduced an automated participant that periodically interrupts the conversation to give nonnative speakers a chance to speak. The AI bot increased participation from 12% to 17% of all words spoken, with nonnative speakers feeling valued and appreciated for their perspectives.
A new study found that reflecting on life values before a debate can inspire individuals' intellectual humility, with 60.6% of participants showing more humility compared to the average person. The researchers suggest this process could lead to more harmonious debates in online and offline worlds.
Eleni Tomazou's project aims to create in vitro and in vivo models of pediatric sarcomas to accelerate drug discovery and precision medicine. Her work could lead to a significant impact on the treatment of these deadly cancers.
A team of researchers has successfully produced green hydrogen from seawater without pre-treatment, achieving nearly 100% efficiency. This breakthrough uses a non-precious and cheap catalyst in a commercial electrolyser, offering a solution to directly utilize seawater for hydrogen production.
A study published in Genome Biology and Evolution found a core genetic toolkit for reproductive division of labor in rudimentary insect societies. The authors identified common genes associated with fundamental social divisions in bees and wasps, suggesting a universal molecular 'theme' for cooperation across species.
A UVA Health survey found that 45.2% of women report taking days off due to menstrual symptoms, affecting energy levels, mood, and work interest. Digital health apps like Flo can help manage symptoms, improve productivity, and reduce leave, with app users being 18-25% less likely to report impacted productivity.
A study with human subjects found that varying training conditions led to better generalization of task performance, even in the presence of irrelevant stimuli. This suggests that more variability in training can lead to improved learning outcomes by enabling the brain to create invariant representations.
Researchers at the University of Florida have found that silver nanoparticles and aminoglycosides work together synergistically to combat antibiotic-resistant bacteria. The combination reduces the amount of antibiotic needed by 22-fold, making it more potent and potentially reducing side effects.
A team of experts led by LSTM has developed a globally relevant, evidence-based patient-centred set of measurements for snakebite clinical trials. The new core outcome measures aim to standardise trial methodology and support the needs of patients and clinicians worldwide.
A University of Maryland School of Medicine physician-scientist leads a research program to develop a bio-synthetic whole-blood product for easy use in the field, potentially saving thousands of lives. The product will be designed to stabilize blood pressure and facilitate blood clotting.
Researchers at Toyohashi University of Technology elucidated the decomposition behavior of electrolytes in cathode composites of all-solid-state lithium-sulfur batteries. The sulfide solid electrolytes convert to thiophosphates with long-chain cross-linked sulfur during charging and discharging cycles, governing battery performance.
Researchers discovered a single protein called Gr8a that plays an inhibitory role in mating decision-making, helping flies avoid inter-breeding with the wrong partner. The findings provide insight into how signal production and perception are tied together, shedding light on pheromone communication.
Researchers developed a method to measure individual biological response to therapy using functional near-infrared spectroscopy, enabling real-time evaluation of radiotherapy's impact on patients. This technique allows for tailored radiation doses to optimize treatment and improve outcomes.
A new framework incorporates plant physiology into fine-scale computer models of wildland fire, improving global fire forecasting. Plants' water and carbon dynamics influence combustion and heat transfer, affecting fire behavior and effects.
A new study by University of California, Berkeley researchers suggests that iconic desert plants came preadapted to stresses of arid living. The rock daisy study found these pioneers developed adaptations on dry, exposed rock outcrops within older areas, making it easier for them to thrive in expanding deserts.
A two-year study by Rutgers researcher Jinjing Jenny Wang found that babies between 14 and 19 months old benefit from watching counting videos, engaging them with real-life scenarios. The study's findings suggest these videos could reduce disparities in children who may not receive enough counting exposure from caregivers.
A new study uses CRISPR-Cas9 to modify a gene that makes plants susceptible to viruses, resulting in strong resistance to multiple potyvirus isolates. This approach broadens genetic diversity and generates resistance without altering protein function or expression.
Physicist Yana Vaynzof at TU Dresden has been awarded an ERC Consolidator Grant to investigate metal halide perovskites and develop novel methods for vapor deposition. Psychologist Philipp Kanske also received an ERC Consolidator Grant to study the neural basis of empathy and perspective-taking in social interactions.
A new study found that women with pre-pregnancy migraine had greater risks of preterm delivery, gestational hypertension, and preeclampsia. Migraine with aura was associated with a higher risk of preeclampsia than without aura.
Biologists found songbirds can assess when predation risk from northern pygmy owls is highest and when there's safety in numbers. Mobbing behavior peaked in late summer and autumn when young birds are most vulnerable.
A new study finds that obesity-related neurodegeneration mimics Alzheimer's disease, with grey matter atrophy patterns similar in both groups. The researchers suggest that controlling excess weight could lead to improved health outcomes and slowed cognitive decline.
The EU's Medical Devices Regulation and Digital Markets Act pose challenges for Google and Apple, which must balance enforcement and oversight with their interests as distributors and developers. New regulations aim to improve app store models and ensure safe provision of digital health applications.
A new study estimates that urban heat islands cause 6,700 premature deaths annually in European cities, with increasing tree cover up to 30% reducing temperature and mortality rates. Cities with high excess heat-mortality rates can benefit most from this measure.
A new study found that sleep medications increase the risk of dementia in white adults. However, the relationship between sleep medications and dementia risk varies by medication type and socio-economic status. The study suggests that patients with poor sleep should consider alternative solutions before taking medications.
Numerical simulations suggest that Mimas' Herschel impact basin is compatible with a thinning ice shell and geologically young ocean. The results imply that the present-day ocean within Mimas must have been warming and expanding since its formation, potentially making it an emerging ocean world.
Researchers studied Ingenuity's historic flights on Mars to calculate dust cloud size and mass. The results supported engineering models, paving the way for future extraterrestrial rotorcraft missions.
The University of Alberta and Amii are recruiting 20 new Canada CIFAR AI Chairs to focus on groundbreaking AI research in health, energy, and Indigenous initiatives. This initiative aims to accelerate opportunities for responsible commercialization of AI, driving future economic growth.
Philip J.W. Moll's ERC Consolidator Grant aims to engineer electronic interactions within a single material, exploring new paradigms for interfaces between two regions of different electronic behaviors, such as superconductivity and magnetism.
Researchers developed a thin layer of silicon oxide to protect perovskite solar cells from radiation and extreme temperatures in space. The coating preserved efficiency and increased lifetime by up to 99% compared to unprotected cells.
Researchers developed a new photo-oxidation method to efficiently synthesize pharmaceutical intermediates and polyurethane from perchloroethylene, a common dry cleaning solvent. The method yields high-quality compounds with minimal environmental impact, offering a promising alternative for sustainable chemical recycling.
The study found that almost 92% of Africa's maize growing areas support year-round growth of fall armyworm. Almost 95% of the crop is also deemed climatically suitable for fall armyworm, with multiple pests posing significant risks.
Researchers have developed a new way to produce mirrors that can withstand extremely high powers, enabling the creation of small footprint, ultra-high-power laser systems. This breakthrough has significant implications for various fields such as medicine, biology, and physics.
Researchers developed a haptics-based automated driving system that encourages continuous engagement between drivers and automation. The system achieves this through three functionalities: interaction, arbitration, and inclusion, resulting in increased safety and comfort for human drivers.
Researchers discovered the most efficient way to produce ammonia through electrochemical synthesis, increasing its sustainability. The D5 step site on ruthenium nanoparticles was found to be the most active site for the nitrogen reduction reaction.
A Penn State-led study found that the timing of disruptions is more damaging to invertebrates than severity. Aquatic organisms in Sycamore Creek responded to winter floods and summer monsoon events differently, with some populations being resistant or resilient to disturbances.
Men who would use PrEP prefer long-acting injectable medications due to lower cost and reduced side effects. The survey found that respondents ranked costs and potential side effects as the most important factors in considering whether to take PrEP, with a preference for lower-cost options.
Fossils of a type of sea worm, Iotuba chengjiangensis, have provided new insights into the evolution of annelid worms. The discovery suggests that these worms diversified into different lineages around 515 million years ago, during the Cambrian explosion.
A recent study published in Forest Ecology and Management found that deer browsing had relatively little long-term impact on two tree species in a northern forest. Researchers discovered that seedling survival and growth were more greatly influenced by light availability, soil nitrogen, and size attained before gaps were created.
As abortion restrictions take effect, acute care surgeons should prepare to treat complications such as infection, haemorrhage, and injury to the uterus, bowel, bladder, and circulatory system. Experts argue that providers have an ethical duty to protect patient privacy and not report complications to law enforcement.
Researchers at the University of Rochester develop a new method to control electron spin in silicon quantum dots, paving the way for practical silicon-based quantum computers. The technique harnesses spin-valley coupling to manipulate qubits without oscillating magnetic fields.
The new optical resonator developed by Capasso's team provides precise control over the mode of light and enables multi-mode coupled light to exist within the resonator. This breakthrough could influence how resonators are understood and open doors for new capabilities, including fundamental physics experiments and manipulation of mate...
A study of 4,078 cases found that sports-related cardiac arrests in people 65 and older are rare, occurring in only 1.9% of cases. Those who experienced exercise-related cardiac arrests tended to have fewer cardiovascular risk factors and better health outcomes.
Research led by Christina Aiello shows that GPS tracking data and computer simulations can predict animal movements, helping optimize habitat connectivity enhancement projects. The study identified eight populations of bighorn sheep where barrier removal would increase accessible habitat.
A study published in Nature Food found that hyper-palatable foods consistently led to increased calorie intake across four different dietary patterns. These meals were characterized by high energy density, fast eating rates, and specific combinations of fat, sugar, sodium, and carbohydrates.
Researchers from Tsinghua University develop a new strategy to decouple temperature and pressure in hydrothermal carbonization, breaking the temperature limit. This process produces high-quality carbon microspheres with abundant oxygen-containing functional groups and good thermal stability, suitable for various applications including ...
Etoposide's impact on DNA structure has been untangled by Cornell researchers using optical tweezers and magnetic tweezers. The study found that etoposide promotes DNA loop trapping and barrier formation by topoisomerase II, enabling the creation of sensitive screening tools for improving patient treatment.
Researchers found that rock ants display a striking regular meandering pattern when exploring their surroundings, combining systematic movement with random walks. This behavior may make their search more efficient by reducing the frequency of crossing their own paths.
Researchers at MIT have discovered a way to switch graphene's superconductivity on and off with short electric pulses, opening up new possibilities for ultrafast brain-inspired electronics. This discovery could lead to energy-efficient superconducting transistors for neuromorphic devices.
An experimental vaccine against Marburg virus demonstrated a good safety profile and induced strong, long-lasting immunity in a Phase 1 clinical trial. The vaccine candidate, cAd3-Marburg, induced an immune response in 95% of participants and maintained that response for over 48 weeks.
A new study published by the University of Leeds reveals that people with arthritis are 20% less likely to be in work compared to their peers without the condition. The most striking finding is that non-university educated women aged 60-plus are at least 37% less likely to be in work if they have arthritis.
Researchers found that seminal fluid protein sex peptide alters the female fly's behavior by changing the expression of genes involved in metabolism and the circadian clock. Post-mating, sex peptide increases egg-laying, aggression, activity and feeding while reducing sleep and interest in mating.
A study by Osaka University compared the sensitivity of rapid antigen tests (RATs) and polymerase chain reaction (PCR) tests for the Omicron variant of COVID-19. The results showed that RATs had a high enough sensitivity to suggest frequent testing using RATs may still be the best approach.
Researchers developed a microfluidic device to model the spleen's filtration function in patients with sickle cell disease. The study found that low oxygen levels can cause the spleen's filters to become clogged, while boosting oxygen levels can unclog them, potentially explaining how blood transfusions help patients.
A new study reveals a low-cost sensing glove that can identify fetal position and measure force applied to the fetal skull during labor, potentially improving birth outcomes in low-resource regions. The technology provides real-time data during vaginal exams, allowing clinicians to take corrective action early on.
A new study finds COVID-19 was the top underlying cause of death from infectious disease among children and young people aged 0–19 years. The risk of death from COVID-19 was substantially lower compared to other age groups, but still a significant concern, with over 1,300 child deaths attributed to the virus in the US.
A study found that immune checkpoint inhibitors enhance chemotherapy-induced neuropathic pain by blocking interaction between macrophages and neurons via PD1-PDL1 synergy. This discovery could lead to the development of therapeutic alternatives to prevent pain while maintaining anti-neoplastic effects.