Researchers identify a new small molecule inhibitor for use against Alzheimer’s disease
A team of researchers at Massachusetts General Hospital has identified a new small molecule inhibitor, PB118, that significantly reduces Alzheimer's disease neuropathology. The inhibitor targets histone deacetylase 6 (HDAC6), which is overexpressed in the brain of AD patients.
SourceMassachusetts General Hospital·JournalAdvanced Science·TypeExperimental study·DateNov 25, 2023