A study of 637 callers found misoprostol alone to be a safe and effective method for terminating pregnancies. The findings suggest strategies should be explored to maximize its effectiveness in clinical and nonclinical settings.
A Dartmouth study analyzing declassified Cold War satellite imagery identified 396 previously undocumented Roman forts across the northern Fertile Crescent. The forts were constructed from east to west, contradicting Father Antoine Poidebard's north-south axis claim and suggesting a more complex distribution along Rome's eastern frontier.
A Cornell University-led team used an underwater robot to explore the ocean conditions beneath an Antarctic ice shelf, discovering a new circulation pattern involving a jet funneling water sideways through crevasses. The findings improve modeling of ice shelf melting and freezing rates, which can impact global sea-level rise.
A team of researchers from the University of Liège has studied the mechanisms governing water droplet speed along fibers. They found that thicker fibers result in lower speeds, but unexpected behavior occurs when two fibers are bundled together, leading to faster droplet movement.
Ant communities in Okinawa Island show reduced seasonal behavior in areas with more human development. Researchers found that ant populations in developed sites are less predictable and have diminished seasonality compared to forested areas. The study highlights the impact of human activities on insect populations and ecosystem services.
Researchers at the University of Nottingham have discovered a protein that seals plant roots to regulate nutrient and water uptake from the soil. This finding has significant implications for developing climate-proof crops with reduced water and chemical fertilizer requirements.
A new framework for microbiome research involving Indigenous communities has been developed, prioritizing collaboration and Indigenous sovereignty. The framework aims to ensure that Indigenous communities reap the benefits from their contributions to science.
Researchers developed an AI-powered method to measure urban decay using street view images, identifying object classes like potholes and graffiti. The model showed promise in detecting urban decline in cities like San Francisco and Mexico City, with potential applications for informing urban policy and planning.
A six-month randomized clinical trial involving 75 adults with type 2 diabetes found that time-restricted eating was effective for weight loss. This novel dietary approach lowered hemoglobin A1c levels without calorie counting, offering potential for improved blood sugar management and overall health.
A study questions the ongoing arms race between bats and insects, finding that one bat species' low calls are likely due to its evolutionary history. The barbastelle, a hawking bat, has quieter calls than other bats but is likely descended from a gleaner that hunted on surfaces.
A new method called TWC-Swin effectively restores holographic images even under low spatial coherence and arbitrary turbulence, surpassing traditional convolutional network-based methods. The study demonstrates strong generalization capabilities, extending its application to unseen scenes.
A novel replacement strategy using CRISPR-Cas9 and recombinant DNA donor vectors is proposed to precisely replace disease-causing genes in SCID patients. This approach preserves regulatory elements and intronic sequences, reducing the risk of unregulated gene expression.
Scientists at Imperial College London have found that cells within hair follicles can detect touch and release neurotransmitters serotonin and histamine. This discovery may help understand histamine's role in inflammatory skin diseases like eczema.
The TMIST breast cancer screening trial is expanding to Thailand, aiming to improve outcomes for Black and Hispanic women. The trial, led by the ECOG-ACRIN Cancer Research Group, is comparing 3-D and 2-D mammography in 128,905 women to better inform tailored future screenings.
The Perinatal LAW Project, a medical-legal partnership, helps pregnant and postpartum patients tackle unmet legal needs, such as housing and financial insecurity. By integrating lawyers into care teams, healthcare providers can better support patients' health-harming legal issues, leading to improved birth outcomes.
A new study published in JAMA Network Open found time-restricted eating to be safe and effective for people with Type 2 diabetes, helping them lose weight and control blood sugar levels. Participants who followed the time-restricted eating plan had an easier time sticking to it than those on a calorie-reduced diet.
Researchers identified simple food swaps that can make a big difference in an individual's carbon footprint without drastic dietary overhaul. The suggested changes include replacing beef with chicken or plant-based milk, which could reduce the nation's food-related carbon footprint by more than 35% and improve overall dietary quality.
A study by Aalto University reveals that online games employ deceptive data collection practices, often hiding information behind complex legal jargon. Players are often unaware of the risks and may feel compelled to conceal their identities or personal data to maintain privacy.
New research suggests that meltwater flowing out to sea from beneath Antarctic glaciers is accelerating their retreat and contributing to global sea-level rise. The study's simulations indicate that this process could make a significant contribution to sea-level rise by 2300, potentially up to 15%.
Researchers at McGill University found that people who use sunscreen are more likely to develop skin cancer due to inadequate application or excessive sun exposure. Sunscreen is not the most effective way to protect against skin cancer, with clothing and avoidance being better options.
Small cell lung cancers metastasize to the brain by convincing astrocytes they are baby neurons in need of protection. Blocking this signal may slow or stop brain metastasis growth, according to a Stanford Medicine study.
Researchers aim to validate noninvasive screening test using exosomal microRNAs for early detection of pancreatic ductal adenocarcinoma. The goal is to reduce unnecessary surgeries and improve health equity by including diverse populations in the study.
Researchers found that most allegedly biodegradable plastic items sold by Brazilian supermarkets are actually oxo-degradable plastics banned in several countries. The products cost 125% more than conventional alternatives and failed to meet minimum requirements for genuine biodegradability.
New research reveals that endangered whales and dolphins inhabit the Hellenic Trench off Greece year-round, challenging seismic surveys and oil and gas exploration. The study confirms the presence of four species, including sperm whales, in both summer and winter, highlighting the need for conservation measures.
A research group led by Professor Kaspar Althoefer has been awarded a €10m ERC Synergy grant to develop a revolutionary new system for screening and treating colorectal cancer. The system, which combines medical robotics, artificial intelligence, and minimally invasive surgery, aims to improve patient outcomes and quality of life.
Researchers have discovered a protostar leaving its birthplace using high-resolution molecular spectral lines. The study found the core to have a significant blue shift of -2.3 km/s relative to its parental cloud, indicating an escape velocity less than 4,000 years ago.
A new study has identified 16 major risk factors for severe RSV infection in children under one year of age. The researchers created a clinical prediction model that performed well in both Finland and Sweden, highlighting the need for targeted prevention measures for high-risk infants.
The European Research Council has funded a groundbreaking project, SWIMS, to develop bio-inspired wireless multimodal sensory systems. The approach is based on the intricate workings of insects, aiming to reduce energy consumption and create sustainable Internet of Things nodes.
Scientists at the University of Würzburg validated an alternate theory proposing the spinaron effect, where individual cobalt atoms exhibit perpetual motion and interact with electrons in a unique manner. This discovery could lead to breakthroughs in magnetic information encoding and transportation, making IT more energy-efficient.
A UCLA-led study shows datopotamab deruxtecan, a Trop-2 directed antibody-drug conjugate, significantly improves progression-free survival in patients with metastatic non-small cell lung cancer. The treatment primarily benefits patients with non-squamous tumors, reducing disease progression and improving overall survival.
Researchers at Osaka University have developed a novel platform that combines nanopore technology with artificial intelligence to detect different coronavirus variants quickly. The platform was tested on 241 saliva samples and detected the Omicron variant 100% of the time.
Researchers at Karlsruhe Institute of Technology (KIT) discovered that applying mechanical pressure to strontium ruthenate increases its transition temperature and facilitates deformation. This is attributed to quantum mechanics resonance of electron oscillations, making the material softer.
Researchers propose retroelement-based gene editing as a safer alternative to CRISPR-Cas systems due to reduced risk of DNA double strand breaks and unwanted chromosomal modifications. This approach leverages endogenous mobile genetic elements, which can be programmed for targeted genomic engineering without generating DSB.
A secondary analysis of the Women's Ischemia Syndrome Evaluation (WISE) cohort study found that black and non-black women with obstructive coronary artery disease had similar long-term cardiovascular outcomes. The study suggests that guideline-based treatment, including statins and ACE inhibitors, may reduce racial disparities in cardi...
New research identifies two modes of rapid intensification, one linked to favorable environmental conditions and warm surface waters, the other triggered by major bursts of thunderstorms far from the storm's center. These findings may lead to better understanding and prediction of catastrophic hurricanes.
A study by Brigham researchers found that the COVID-19 pandemic led to a sharp decline in surgical abortions for commercially insured patients, with no concurrent increase in medical abortions. The rate of surgical abortions remained below pre-pandemic levels through June 2022.
A new tool has been developed to rapidly grow cancer-killing white blood cells, called T cells, which could advance the availability of immunotherapy. The bioreactor is 30% faster than current technologies and can be self-contained in a sterile cabinet.
A new method, probability of food security (PFS), measures food insecurity likelihood and finds that a third of US households experienced at least temporary food insecurity. PFS identifies chronic and transitory food insecurity groups for more refined policy addressing.
Researchers developed a ceria nanoparticle-immobilized mesenchymal stem cell nanovesicle hybrid system to treat rheumatoid arthritis. This approach provides both immediate pain relief through ROS scavenging and long-term immune tolerance by delivering immunomodulatory cytokines.
A study of wild chimpanzees in Uganda's Kibale National Park found that females can experience menopause and postreproductive survival. The research challenged the long-held assumption that this trait is unique to humans, suggesting it may be a species-typical trait in chimpanzees.
A portable virtual reality system will be developed to quickly assess traumatic brain injuries in remote locations, utilizing AI-powered machine learning algorithms. The system aims to provide a rapid and fine-grained assessment of neurocognitive abilities, increasing the survivability and readiness of US soldiers.
A new international clinical trial found that a drug candidate is highly effective in treating Acanthamoeba keratitis with medical cure rates of 87%, reducing the risk of poor visual outcomes and surgery. The treatment, low concentration polihexanide (PHMB 0.08%), follows a novel and evidence-based protocol.
Researchers found that smooth surfaces like tile and lacquer-coated wood have low bacterial growth, while porous surfaces like untreated oak increase the risk of contamination. Treated wood is recommended as surface material to prevent bacterial transmission via dry hands.
A study in mice finds that two proteins, MAP6 and Kv3.1, interact to control movement, memory, and anxiety. Disrupting this interaction can lead to behavioral changes, including hyperactivity and impaired memory, highlighting potential new targets for schizophrenia treatment.
University of Leicester astronomers confirm the existence of an infrared aurora on Uranus, offering clues to its magnetic fields and potential for life. The discovery may also help identify other habitable planets with similar characteristics.
A new study by York University researchers suggests that people with autism are less likely to be affected by the bystander effect, which can lead to inaction in the face of wrongdoing. The findings suggest that neurodivergent individuals can bring unique benefits to workplaces.
Researchers observed a gamma-ray burst from a kilonova, the collision of two compact neutron stars, using the James Webb Space Telescope. The data revealed the creation of the element tellurium, which had not been recognized before, and provided new insights into the formation of heavy elements in the universe.
Researchers used gut organoids to study gut cell differentiation, identifying ZNF800 as a key regulator of enteroendocrine cells. The discovery could have implications for understanding gastrointestinal diseases and endocrine disorders.
Scientists generate multiple quasiparticles simultaneously in a quantum gas and observe their complex interactions, including attractive and repulsive behavior. Quantum statistics plays a crucial role in these interactions, which are essential for understanding fundamental mechanisms of nature.
Researchers successfully controlled spin waves by using a superconducting electrode, which acts as a mirror to reflect the magnetic field back to the spin wave. This breakthrough offers an energy-efficient alternative to electronics and opens doors for designing new circuits based on spin waves and superconductors.
A team of Osaka University researchers discovered a link between Rab32 and Rab38 proteins, crucial for both hair pigmentation and bone resorption. Double-knockout mice showed increased bone density and altered physical characteristics, highlighting the importance of these proteins in maintaining bone homeostasis.
A survey of 1,005 parents found that internet use by adolescents has both positive and negative effects, including concerns about addiction and cyberbullying. The study revealed that twice as many parents reported specific concerns about internet addiction than substance addiction.
Researchers identified two fungus strains, Cyberlindnera jadinii and Kluyveromyces lactis, with potential probiotic effects on gut inflammation. These strains may offer a new way to develop probiotics and treat inflammatory bowel diseases like Crohn's disease and ulcerative colitis.
Researchers at UC Davis Health found that KSHV infection can lead to inflammation and dysregulation of the immune system. The study used single-cell sequencing and other technologies to investigate the role of IL-6 in KSHV-mediated reprogramming of immune cells.
A nationwide study by Radboud University Medical Center found that approximately 32 patients in the Netherlands are in a minimally conscious state after severe brain injury. These patients were on average 45 years old and showed signs of consciousness, such as following simple commands or showing emotions.
A new study found that making simple substitutions like switching from beef to chicken or plant-based milk can reduce the average American's carbon footprint from food by 35%, while also boosting diet quality by between 4-10%. These small changes can have a significant impact on both climate and health outcomes.
Researchers from the Max Planck Research Group aim to investigate the local immune system of the liver to develop new immunotherapy strategies for metastatic diseases. They will examine tissue and tumor samples using state-of-the-art techniques to identify key molecules and checkpoints in complex cellular interaction networks.
Researchers discovered a wide range of organisms, including microbes and humans, exhibit similar movement patterns to navigate their surroundings. These patterns are thought to be linked to uncertainty management in the brain.
Researchers have identified 38 businesses marketing unapproved stem cell treatments and exosome therapies for preventing and treating COVID-19. Many clinics claim to treat Long COVID, with some charging up to $25,000 for 'treatments'. Regulatory bodies must act to protect patients from misleading claims.
Researchers argue that AI systems can be designed to follow human law, suggesting a more integrated approach to regulation. The study proposes training AI agents in legal frameworks and using large language models to monitor and shape their behavior.