A study led by Oregon State University has identified the mechanism behind omega-3 supplements' effectiveness in combating nonalcoholic steatohepatitis (NASH), a liver condition associated with metabolic syndrome. Betacellulin, a protein growth factor, plays a crucial role in the disease's progression and scarring.
A comprehensive study found that eating whole eggs had a positive impact on nutrient density, hematocrit levels, and immune function, while reducing the negative effects of egg whites. The study also explored differences in responses between women taking birth control pills and those not.
Researchers developed a new tool to evaluate clinical trial results, allowing for more complex research questions and faster treatment access. The 'Chauhan Weighted Trajectory Analysis' can assess multiple outcomes in one graph, capturing disease severity and treatment effectiveness.
A new approach using deep learning speeds up supernova simulation by 99%, enabling more accurate modeling of galaxy evolution. This breakthrough could also apply to climate and earthquake simulations, providing valuable insights into complex phenomena.
A study analyzing ancient Cancun Island remains found that immigrants from the Maya lowlands were treated similarly to locals in terms of food and burial practices. The findings suggest whole families moved residence across Mesoamerica and integrated into new societies, challenging previous assumptions about foreign treatment.
Researchers developed a single model that predicts population fluctuations in urban employment, human gut microbiomes, and tropical forests. The model, SLRM, generates a narrow distribution of the most likely trajectories, allowing for prediction and response to variability across multiple domains.
A study in fruit flies reveals a potential connection between a respiratory system defect and the development of aortic aneurysms in humans. Researchers identified proteins that play a crucial role in maintaining tube structure and integrity, which may also be relevant to human tubular diseases.
A study of 9,479 participants identified racial and ethnic disparities in breast cancer survival, highlighting the need for targeted interventions to improve outcomes for at-risk subgroups. The findings suggest that focused care approaches can address these disparities and promote more equitable treatment.
Listening to preferred music reduces pain intensity and unpleasantness, while emotional responses play a key role in predicting its effect. The study found that moving or bittersweet emotional themes are associated with lower pain ratings.
Research at Osaka University finds that warming up can rapidly activate contractile proteins and improve muscle performance, particularly in skeletal muscles. This difference may allow skeletal muscles to contract quickly upon warming, saving energy and resting when needed.
Researchers found changes in microglial cells, a specialized subset of immune cells, that may worsen schizophrenia risk in adolescents. The study, published in Nature Communications, suggests that THC exposure during adolescence can lead to long-lasting negative effects on brain development and function.
A new study reveals that autophagy plays a crucial role in the gradual loss of DNA content in diploid Saccharomyces cerevisiae cells undergoing chronological aging. The researchers found that only diploids survived, and autophagy induction was responsible for the DNA loss.
Researchers investigated rooster mirror self-recognition, finding that their behavior indicates recognition despite failed traditional tests. The study's results provide new insights into the cognitive ecology of mirror self-recognition in birds.
Researchers from Pusan National University have developed pricing formulas for vulnerable timer options, which can help reduce investment risks. The study found that these options are more effective than standard timer options in managing credit risk.
Researchers at Baylor College of Medicine identified a small molecule named 5D4 that can suppress breast and ovarian cancer growth. 5D4 works by binding to TopBP1 protein in cancer cells, disrupting interactions with multiple pathways that promote cancer growth. Combining 5D4 with PARP inhibitors enhances anti-cancer activity.
A brain-computer interface (BCI) has been successfully used to restore control of home devices for a patient with ALS, allowing the individual to navigate a communication board and smart devices without recalibration. The BCI device was implanted on the surface of the brain areas responsible for speech and upper limb function, enabling...
Researchers have confirmed that genes associated with East Asian and Native American ancestry explain lighter skin in people of these descent, rather than European genes. This discovery has broad implications for genetic research and the prevention of melanoma, particularly in Europeans.
The Cumming Global Centre for Pandemic Therapeutics is offering global grants of up to $200,000 per annum for three years to develop novel therapeutics for pathogens of pandemic potential. Researchers are invited to submit expressions of interest for Round Two of the Foundation Grants program.
Scientists have developed a novel organ-on-a-chip device with customizable screen-printed electrodes for measuring endothelial barrier integrity. The device overcomes traditional electrode fabrication challenges, providing a reliable and accurate method for studying the crucial roles of endothelial barriers in healthy and disease states.
A brain injury expert is calling for reforms to the Uniform Determination of Death Act, citing support from 83% of medical and advocacy organizations. The expert argues that the legal definition of death should align with medical standards, including clarifying what brain functions must be lost to declare someone legally dead.
Researchers found that thyroid hormones of the mother during pregnancy affect the later activity of brown adipose tissue in offspring. High maternal thyroid hormone levels were associated with more active brown fat in offspring.
The What3Words geocoding algorithm creates potential for confusing different nearby addresses, which could have serious implications in emergency situations. Simulation-based analysis highlights the need for improved spatial reasoning and algorithmic design to mitigate these risks.
A year-long clinical trial found sustained remission of polymyalgia rheumatica in 28% of patients taking sarilumab, compared to 10% of those on placebo. The treatment showed promise in reducing relapse and improving outcomes for patients tapering their steroid medication.
Korea Electrotechnology Research Institute (KERI) developed a high-efficiency multistage thermoelectric module, surpassing traditional single-stage modules by over 3% in efficiency. This innovation has applications beyond space exploration, including industrial waste heat recovery and temperature control of electric vehicle batteries.
Researchers developed a new type of laser using Dirac-vortex photonic crystal lasers on silicon, offering high performance and robustness. The discovery paves the way for next-generation silicon-based photonic integrated circuits.
A new study has discovered microfossils resembling modern-day algae that lived in the oceans during the Cambrian Period, around half a billion years ago. The findings suggest that early animals were evolving to feed on plankton, starting a predator-prey relationship that continues to this day.
Research found that nematodes can sense danger by smell, triggering a neural circuit that induces a response in other tissues, leading to a longer lifespan and less protein aggregation. The study suggests that manipulating perceptions of chemical substances could be a route to intervention in neurodegenerative diseases.
Researchers at ETH Zurich analyze Mars' seismic data and computer simulations to determine the planet's interior structure. They discover a layer of liquid silicate (magma) about 150 km thick between the core and mantle, contradicting initial estimates of the Martian core's density.
Researchers at Harvard John A. Paulson School of Engineering and Applied Sciences have developed a system that uses atomic vacancies in silicon carbide to measure the stability and quality of acoustic resonators, which could improve communications and offer new control for quantum computing. The technique also allows for acoustically-c...
Researchers created a rapid assessment tool, FAST, to estimate the depth of flooding and population exposure. The analysis estimated adaptation costs between $1.5-$3.6 billion for 7.4 million people affected by 1-2 meters of flood depth.
A study by Nagoya University found that children with a genetic predisposition to autism spectrum disorder (ASD) used screens for longer periods. Children with attention deficit hyperactivity disorder (ADHD) also increased their screen time as they grew older, suggesting a potential link between genetic risk and excessive screen use.
A randomized clinical trial involving 126 patients found that landiolol did not prevent organ failure in those with established septic shock. The study concluded that this beta-blocker is not a suitable treatment option for managing tachycardia in these patients.
A study shows pigeons tackle complex problems using associative learning and error correction, similar to AI models. Researchers used an AI model to replicate the pigeons' behavior, finding strong evidence for the similarities between pigeon and AI learning mechanisms.
A randomized clinical trial of 524 trauma patients found that adding sigh breaths to mechanical ventilation did not increase ventilator-free days. However, prespecified secondary data suggest that sighs are well-tolerated and may improve clinical outcomes in this patient population.
A first-ever study of wartime deepfakes examines the effects of artificially manipulated audio-visual content on news media and user trust during the Russian-Ukrainian war. The research found that fears of deepfakes often undermine users' trust in authentic footage, and efforts to raise awareness may even cause more harm.
Researchers used seismic data to locate and identify a thin layer of molten silicates overlying Mars' metallic core. The discovery reveals a denser and smaller Martian core, aligning with other geophysical data and analysis of Martian meteorites. This finding provides new insights into how Mars formed, evolved, and became a barren planet.
Researchers investigating sihek health have found that female birds are at greater risk for death and disease than males. The study also highlights reproductive diseases as a major threat to the species' survival, with females succumbing to these diseases more frequently.
A collected sample of 30 million Indian tweets revealed 2% containing misogynistic language, with rates rising during the COVID-19 pandemic. The study used a taxonomy to classify online misogyny and measured its prevalence in India.
Older Black Americans are more likely to receive low value acute diagnostic tests than older White Americans, while older White Americans were more likely to receive low value screening tests and treatments. These differences persisted within health systems and were driven by differential treatment within the system.
A study in sustainable-use reserves found local game species abundance decreases about 5 kilometers from nearest human community. Human impact on biodiversity is mitigated by management strategies, supporting community-based wildlife management for food security and conservation.
A new study suggests that combining therapeutic touch and music can significantly improve sleep quality, reduce menopause symptoms, and enhance overall quality of life in women undergoing menopause. The study involved over 100 menopausal women who experienced significant improvements after four weeks of treatment.
A new study published in the Proceedings of the National Academy of Sciences found that exposure to norm-violating rhetoric from politicians like Donald Trump can reduce support for certain core democratic principles. The researchers found that Trump supporters who were shown his antidemocratic tweets indicated less support for partici...
The study reveals that human-driven global nutrient imbalances are linked to increased risk of diseases such as coeliac and cancer. The research proposes a new strategy for managing fertilizers by adjusting the N:P ratio, potentially enhancing therapy effectiveness against certain cancers.
A new study from the University of Copenhagen demonstrates that 10-20-30 interval training is effective for improving running times and overall fitness, even at 80% sprint intensity. This type of training benefits both blood pressure and cholesterol levels.
Scientists discovered a molten silicate layer beneath the Martian mantle using InSight mission data, contradicting earlier assumptions about the planet's internal structure. This new finding suggests that Mars experienced an early magma ocean stage and provides insights into the formation of its core.
A patient at OHSU received a single stimulator implanted in the brain to effectively control two life-altering conditions: seizures caused by epilepsy and compulsive behavior caused by obsessive-compulsive disorder. The treatment, known as responsive neurostimulation system (RNS), has dramatically improved Pearson's quality of life.
New research suggests that unilateral divorce laws could lead to improved women's welfare by reducing the time spent on household chores. This shift in responsibility could result in more time devoted to personal care and leisure activities.
New research reveals widespread harassment and stereotyping of women in coastal sciences, affecting their ability to participate in fieldwork and advance their careers. Women often experience objectification, discrimination, and micro-aggressions, which can be traumatic and disadvantage them professionally.
A new study reveals that chloroplasts are essential for plant immunity, with stromules forming around the nucleus to transport pro-defense signals. Researchers have identified a key protein involved in stromule biogenesis during immunity, opening up new avenues for understanding and engineering resistance to pathogens.
Researchers at New York University developed a novel learning procedure called Meta-learning for Compositionality (MLC) that enables neural networks to make compositional generalizations. MLC outperforms existing approaches and is on par with, and in some cases better than, human performance.
Researchers found that sunflower stem extracts can prevent gray mold in blueberries by destroying the fungus's plasma membrane and preventing it from forming biofilms. The extracts protected almost half of the berries from mold growth over six days.
The authors argue that tackling climate change and biodiversity loss requires a unified approach, as both crises have devastating impacts on human health. The World Health Organization should declare the indivisible climate and nature crisis as a global health emergency.
A study published in PLOS ONE found correlations between climate change and human population trends in Central European regions. During warm periods, populations increased due to improved crops and economies, while during cold periods, populations decreased, leading to cultural shifts and potential social inequality.
A recent study published in the British Journal of Psychiatry found that individuals with severe mental illness were 50% more likely to die from all causes following a COVID-19 infection. The research also highlighted regional disparities and differences in mortality risk based on ethnicity and geographical location.
A new study published in Science Advances suggests that a decades-old anti-anxiety drug can improve the effectiveness of chemo-radiotherapy towards glioblastoma, the most common and lethal brain cancer. The researchers found that the drug trifluoperazine can re-sensitize tumor cells to both therapies, leading to improved patient survival.
Researchers found that increased homozygosity, indicating a shared ancestor, leads to negative effects on fertility in the Himba population. The study, which analyzed genetic data from 681 individuals, showed that higher levels of inbreeding resulted in lower reproductive success among post-reproductive women.
Researchers identified a novel measure, the 'd factor', linking distractibility with ADHD symptoms and hyperfocus. The study found strong statistical links between external distraction, intrusive thoughts, and mind-wandering, suggesting a general distractibility trait.
A study by UCLA researchers found that children of parents with adverse childhood experiences are at increased risk of arrests and convictions by young adulthood. Positive childhood experiences were not observed to provide a balance for the adverse ones.
A new study by Princeton researchers reveals widespread illegal hunting in China, resulting in the loss of over 20% of native species, including endangered ones. The study estimates that at least 28% of China's terrestrial vertebrate species may have been taken during the six-year period.
A Rutgers study found that 70.5% of law enforcement officers in the US own firearms, with handguns being the most common type. The study also revealed that those with lifetime thoughts of suicide are more likely to own firearms and engage in insecure storage methods.