A Geisinger Health System study found that genomic screening for hereditary hemochromatosis type 1 can identify underdiagnosed cases and encourage treatment. The screening program resulted in 69% of those notified proceeding with a lab test, and 69% of those showing iron overload beginning subsequent treatment.
A collaborative project led by UTHSC researcher Dr. Liza Makowski is exploring the complex interplay between obesity, the immune system, and cancer. The team aims to identify biomarkers that may provide therapeutic guidance for obese patients with specific types of cancers.
Researchers develop TrackerSci to track newborn brain cells' growth and maturity. The study reveals radical shifts in cell types depending on age, with neurons and glial cells declining in elderly brains.
A comprehensive framework for designing marine protected areas has been developed by an international team of scientists. The guidelines prioritize habitat persistence and coastal corridors to help vulnerable species such as turtles, sharks, and lobsters survive climate change. By connecting habitats fractured by human development and ...
A groundbreaking clinical trial launched by the U.S. Army aims to find new treatments for post-traumatic stress disorder (PTSD) in military personnel and veterans. The trial will test multiple drug candidates and examine biological indicators to determine potential treatments.
A new study by researchers at City, University of London found that alt-tech platforms like Gettr are increasingly important for facilitating far-right political discussions. The study shows that users banned from Twitter are up to six times more active on Gettr, sharing toxic content and aligning with far-right news outlets.
Researchers analyzed DNA sequenced datasets of microbes collected from salt marsh sites to study the relationship between cordgrasses and sulfur-cycling microbes. They found diverse microbial communities with varying combinations of genes for sulfate reduction and sulfur oxidation, allowing them to thrive in salt marsh sediments.
The study found that bronchiolitis admissions decreased temporarily during the pandemic but then surged among older patients, suggesting atypical seasonality. Hospitals should prepare for potential outbreaks in unusual timing in 2023.
A recent study led by UNC Greensboro researcher Mathieu Despard found that one-third of frontline healthcare workers experienced food insecurity, with even those earning over $75k facing housing hardship. The study highlights the importance of benefits in mitigating financial insecurity among healthcare workers.
A Baylor College of Medicine study analyzed metabolite data from over 4,000 adults and found no direct link between red meat consumption and markers of inflammation. The researchers suggest that body weight may be the driver of increased systemic inflammation instead.
A new study validates Low-Pass Genome Sequencing (LP GS) as a robust and cost-effective alternative to Chromosomal Microarray Analysis (CMA) for prenatal diagnosis. LP GS detects six additional Copy Number Variations (CNVs) in cases with negative CMA results, highlighting the importance of sequencing depth in its detection sensitivity.
A new study suggests that Venus once had plate tectonics similar to those on early Earth, which could have supported microbial life. The researchers used atmospheric data and computer modeling to show that the planet's current atmosphere and surface pressure would only be possible with an early form of plate tectonics.
A new meta-analysis suggests that high-dose prescription psychostimulants like methylphenidate and dextroamphetamine can lower cravings and reduce stimulant use in people with amphetamine-type stimulant use disorder. The study analyzed ten randomized controlled trials and found that effects may increase with higher dosage.
The study demonstrates experimentally that the electronic and mechanical properties of a metal are connected. Researchers measured lattice distortion as a function of applied stress in the superconducting metal strontium ruthenate, finding changes in mechanical stiffness corresponding to new electronic states becoming occupied.
A study published in Cell Reports Medicine reveals that endometriosis and irritable bowel syndrome (IBS) share common genetic risk factors. This finding explains why patients with one condition may also develop the other, highlighting the need for increased awareness and early diagnosis.
Conduction electrons play a crucial role in the elastic response of Sr2RuO4. Research reveals that a tiny fraction of current-carrying electrons can dominate the others, making the lattice softer. This finding provides new insights into decades-old problems and has implications for future research.
The Cusack group at EMBL Grenoble has provided insights into the interactions of XIAP and RIPK2 molecules involved in gut signalling pathways. This research sheds light on how these molecules interact, revealing a promising drug target for treating inflammatory bowel diseases.
A global platform study has released results on the use of simvastatin to treat severely ill patients with COVID-19, showing a high probability of improving outcomes. In contrast, high-dose vitamin C was found to be ineffective and potentially harmful in critically ill patients, suggesting its use should be discontinued.
Researchers have developed printable circularly polarized luminescence materials that enable flexible 3D imaging. The materials exhibit intense circularly polarized emission and can be used to create large-scale, high-performance integral imaging displays.
Existing UK air pollution regulations will reduce thousands of premature adult deaths, but have limited impact on protecting sensitive ecosystems. The study found that even with the most effective technically feasible measures, air pollution would still harm UK's natural habitats and ecosystems.
Researchers analyzed North American pollen records to track vegetation changes since the end of the Ice Age, concluding that humans have had as much impact on the landscape. The study's findings indicate comparable vegetation changes within the last few hundred years to those accompanying the last epochal transition.
Researchers developed a new way to diagnose bipolar disorder using a simple blood test that can identify up to 30% of patients. The test, combined with digital mental health assessments, can differentiate between major depressive disorder and bipolar disorder.
A study found that patients with cancer who receive payments from industry are more likely to receive non-recommended and low-value treatments. This association was strongest for denosumab, GCSF, and nab-paclitaxel, but not branded drugs. Further research is needed to better understand the impact of industry payments on cancer care.
A French team of researchers has developed a method to produce stable polystyrene dispersions with unprecedentedly large and uniform particle sizes. The team used light-driven processes, overcoming the previous 300-nanometer ceiling limit of UV and blue-light-based photopolymerization systems.
Researchers developed the SOMMA Vigor to Frailty Score to rank older adults from 0 (vigorous) to 12 (frail), predicting their resilience to stress. Patients on the high end of the continuum are up to 31 times more likely to have functional limitations.
Researchers at Stockholm University have discovered a unique ion transporter, SLC9C1, that activates in response to chemo-attractants, triggering increased sperm motility. This finding provides new insights into the intricate mechanisms governing fertilization.
A new study found significant racial and socioeconomic inequities in access to mechanical circulatory support for US patients with cardiogenic shock. Black patients were more likely to experience reduced access to life-saving therapies like mLVAD and ECMO, highlighting systemic disparities.
A team of researchers from East China University of Science and Technology has developed a systematic framework to identify indicator-PPCPs in raw landfill leachate samples. This study provides the first comprehensive analysis of 68 PPCPs in Shanghai, China landfill leachates, helping implement source apportionment in landfills.
A recent investigation found that some English hospitals are using foreign doctors as part of fellowship schemes, paying them less than trust-employed doctors and limiting their benefits. The Academy of Medical Royal Colleges' scheme has seen over 6,986 trainees from countries including Pakistan, Sri Lanka, and India since 2009.
Researchers have made a groundbreaking discovery in positron emission tomography (PET) imaging, enabling more precise removal of glioma cells. The study revealed that early post-administration PET scans can identify the most aggressive tumor areas, leading to faster disease progression and improved treatment outcomes.
A newly described family of jewel wasps, Protoidae, has been found in Cretaceous amber from Lebanon, providing a unique snapshot of the group's early evolution. The discovery reveals striking characteristics, including a long, shovel-like process, which may have assisted with egg-laying and ovipositing.
Researchers at Institute for Systems Biology have made a breakthrough discovery about T cells, finding that the genetically encoded T-cell receptor sequence determines a T cell's function. This fundamental discovery has huge potential for developing custom immune responses to specific antigens.
Researchers at the University of Houston have discovered that microalgae can be used to sequester carbon dioxide and convert it into mass-produced proteins, lipids, and carbohydrates. This process has the potential to transform food production, treat wastewater, and produce sustainable biofuels.
Research by Hokkaido University's Masayo Soma found that Java sparrows show increased swelling in their eye rings when paired with a preferred mate. This change serves as a rapid indicator of mating readiness and plays a crucial role in communication between pair-bonded birds.
Researchers developed 'acoustic touch' smart glasses that translate visual information into distinct sound icons, enhancing the ability of blind or low-vision individuals to navigate their surroundings. The technology significantly improved object recognition and reaching abilities, empowering independence and quality of life.
Scientists have developed a method for controlling brain activity in living organisms using infrared light-controlled drugs. The technique uses mid-infrared light to activate a specific neurotransmitter receptor, providing unparalleled precision in three dimensions.
The James Webb Space Telescope has made its first detection of a heavy element, tellurium, in a star merger. This breakthrough allows scientists to better understand the process by which rare elements are created, and may shed light on other elements near tellurium that could be present.
Digital technologies provide effortless access to novel information, fostering a habit of frequent checking and task-switching. This creates a mismatch between the mind's preference for novelty and modern digital environments' ability to deliver it constantly.
A new study found that Zika virus infection during pregnancy slows fetal growth and affects how infants interact with their mothers in the first month of life. The study also suggests that reducing viral load may be beneficial for infant development.
A meta-analysis of 28 studies involving 154,739 participants found a strong association between childhood traumatic events and adult headache disorders. People who experienced one or more traumatic childhood events were 48% more likely to have headache disorders than those who had not.
A holistic transformation is needed for a sustainable future, and a new study by an international team of researchers explores the Theory of Planetary Social Pedagogy as a driver. This theory applies to all societal sectors and aims to make life meaningful by increasing experiences of belonging and inclusion.
Scientists create molecular model of triglyceride transport in mycobacterial barrier, discovering 'Trojan horse' system to weaken pathogen's defenses. This breakthrough could lead to more effective therapies against tuberculosis.
A new study analyzes Twitter discussions on deepfakes related to the Russian invasion, highlighting negative reactions and positive sentiments towards deepfakes. The researchers found that some users' distrust in real videos increased after exposure to deepfakes.
A new study, funded by a $3 million grant, aims to investigate whether treating insomnia can lower the risk of cardiovascular disease. The SHADES trial will recruit 200 patients and compare those who receive modernized collaborative care with standard primary care for insomnia.
Researchers have discovered that genetic ancestry influences the biology of normal breast tissue and how it factors into the development of aggressive breast cancers. PZP cells, naturally higher in Black women, can influence cancer cell behavior and growth.
A recent study published in JAMA Internal Medicine found that only 18% of physicians portrayed in films are women, despite increasing representation over time. The research highlights the importance of media representation in shaping attitudes towards women in medicine and may contribute to imposter syndrome among underrepresented groups.
Terminating metformin treatment was associated with higher risk of developing dementia in a large cohort of adults. The study of 41,000 participants found that early metformin cessation was linked to increased dementia incidence compared to continued use.
Researchers Joel Mejia and M. Sidury Christiansen are developing a handbook of recommended pedagogical approaches to address exclusionary language in engineering classes. They aim to improve the sense of belonging among multilingual students pursuing STEM careers by guiding faculty on strategies for changing biased language practices.
Researchers develop a new migration strategy that enhances CO2 reduction to CO via reverse water-gas shift reaction in Ru/(TiOx)MnO catalysts. The approach boosts catalytic activity by 3.3 times and improves H-spillover for efficient hydrogen transportation.
Researchers developed smart glasses with an acoustic touch feature similar to human echolocation. The technology enables blind or low-visioned individuals to recognize and reach objects.
A team of researchers at Kyoto University has found that a deficiency in the enzyme B4GALT3 inhibits tumor growth in mice. The study shows that reduced glycosylation on T cell surfaces correlates with increased CD8+ immune cells infiltrating tumors.
Researchers at UMass Amherst have tracked tarpon migration patterns using acoustic telemetry, revealing two distinct subgroups of the species. The study, which gathered data over five years, has significant implications for conservation efforts, as tarpon are listed as vulnerable due to fishing, habitat loss, and degraded water quality.
A team of researchers found that fibroblast cells cultured on substrates with varying degrees of stiffness exhibit changes in cell structure, function, and TGF-β activity, which regulates ECM architecture. This study provides insights into how mechanical forces influence wound healing and tissue development.
Researchers found no significant improvement in primary composite outcomes, including organ support-free days and hospital survival, among hospitalized patients with COVID-19 who received intravenous vitamin C. The study suggests that vitamin C treatment may not be effective in improving patient outcomes for this population.
Research from TU Dortmund University and RWTH Aachen University suggests that marketing academia has focused on identifying new phenomena, but neglected building 'big-picture' frameworks and theories. This limits the field's ability to provide answers to complex marketing problems.
A new AI-driven mapping study from the University of Copenhagen has discovered a billion tons of hidden biomass in Europe, including trees outside forested areas. The research found that countries like Denmark, Netherlands, and UK have significant tree cover outside forests, which can impact biodiversity and climate models.
Researchers have discovered that water and UV radiation can rapidly degrade the crosslinked polymers in diaper liners without the need for chemicals. This process breaks down the chains linking the polymers, turning them into liquid fibers that can be used to create new products such as adhesives and dyes.
Researchers improved biomass-related traits in sheepgrass using a custom genome editing system, revealing its potential for rapid genomic breeding. The study increased understanding of sheepgrass genomics and established a precedent for its genetic improvement.
A new soft sensor developed by UBC and Honda researchers enables touch sensitivity and dexterity in robots, allowing them to pick up fragile objects like an egg or a glass of water. The sensor uses weak electric fields to sense objects, even at a distance, making it suitable for adoption in robots that interact with people.
A new study reveals that the COVID-19 pandemic has significantly impacted end-of-life care, with a growing burden on first-time carers and reduced formal care support services. Researchers advocate for improved resources for wider end-of-life care education, health and social care staff, and identification and assessment of carers.