Researchers found that symptom-triggered testing can pick up early-stage aggressive ovarian cancer in 1 in 4 of those affected. The UK's protocol for picking up early-stage disease is an effective way to diagnose even early-stage ovarian cancer, with complete surgical removal possible in more than three quarters of women.
A study led by Utah mathematicians found that fast decisions reflect biases, while slow decisions do not. Slow deciders make more accurate choices as they accumulate more evidence and consider multiple perspectives.
A clinical trial in Denmark found that offering women further screening opportunities during breast cancer screenings significantly increased their participation and enabled early diagnosis of other cancers. The study used a cluster-randomized crossover design and involved over 27,000 participants.
A new study from Stockholm University provides fresh insights into the Viking Age monetary system, revealing a flexible pricing system that used both oxen and silver as units of payment. The Forsa Ring inscription describes fines paid in these forms, indicating a more practical and efficient financial system.
The study finds that agricultural expansion could lead to a 26% decline in biodiversity and emit almost half of current annual global CO2 emissions. Conservation policies can also have economic benefits, with minimal impact on GDP and reduced greenhouse gas emissions.
Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL) is a rare subtype of Hodgkin lymphoma characterized by a nodular growth pattern and distinctive lymphocyte-predominant cells. The disease typically presents with localized lymphadenopathy and an indolent course, but can transform into diffuse large B-cell lymphoma in approximately...
A new study provides first-of-its-kind data on the pharmacokinetics and safety of intravenous remdesivir in treating SARS-CoV-2 coronavirus in pregnant women. The research reveals that no dose adjustments are necessary for remdesivir when used in pregnant women, with no safety concerns or adverse pregnancy outcomes identified.
A new study shows that empowering women through energy care work can transform community-led renewable energy programmes, promoting gender equality. The research highlights the importance of valuing multiple voices and incorporating diverse practices of care into energy transition policies.
Toxic pollution is the single largest cause of death and poor health, killing up to 9 million people each year. Business can play a critical role in addressing it and mitigating its effects by embracing innovations like adaptive construction and alternative energy options.
Researchers have discovered a novel pathway to wake up dormant neural stem cells, which can produce new neurons aiding brain repair and growth. The study, published in Science Advances, reveals that astrocytes play a key role in reactivating neural stem cells, offering potential new therapies for neurodevelopmental disorders.
A new study from North Carolina State University uncovers the crucial role of position in successful communication dynamics within a large organization. Researchers identified 'shortcuts' across the hierarchy that enable information to flow more quickly than traditional stepwise communication.
A 1-year study found that continuous outdoor exposure with high sunlight intensity was associated with less myopic shift in children. Effective outdoor exposure patterns should be prioritized to prevent myopia in children.
The State of Wildfires report found that carbon emissions from wildfires globally were 16% above average, with Canada and Amazonia experiencing unusually high numbers of fires. Climate change increased the likelihood of extreme wildfires in these regions by at least three times and up to six times.
A clinical trial shows that JAK inhibitors improve autoimmune conditions such as alopecia areata, atopic dermatitis, and psoriasis in people with Down syndrome. The study also observed improvements in arthritis and decreased biomarkers of autoimmune thyroid disease.
A study published in BMJ Open suggests that Australia's high life expectancy can serve as a model for the US to improve its own life expectancy. The research found that Australians have a lower mortality rate from drug overdose, car accidents, and homicide compared to Americans. By adopting similar policies such as investing in public ...
A recent study published in Radiology found that solid lung nodules were present in approximately 42% of non-smoking adults, with prevalence increasing with age. The study suggests that current nodule follow-up guidelines may lead to unnecessary follow-up examinations for low-risk individuals.
A new study found a significant association between higher heme iron intake and type 2 diabetes risk. Participants with the highest heme iron intake had a 26% higher risk of developing T2D than those in the lowest intake group. The researchers also identified key metabolic biomarkers associated with this increased risk.
Researchers analyzed data from 1741 women diagnosed with high-grade serous ovarian cancer and found that symptom-triggered testing can lead to diagnosis of low-disease spread cases. In most cases, complete surgical removal of the cancerous tissue was possible, challenging the assumption that symptoms always signal advanced disease.
Researchers discovered that regulating porphyrin crystal facets can enhance the production of hydrogen peroxide (H2O2) in photocatalysts. The study found that exposing certain crystal surfaces created a strong internal electric field, which increased H2O2 generation rates.
A study published in Cell reveals that Mrc1 is crucial for epigenetic inheritance, ensuring cells maintain their genetic identity and function. The discovery has significant implications for understanding diseases like cancer and aging, where epigenetic landscapes deteriorate over time.
ACS Fall 2024 will feature over 10,000 presentations on cutting-edge scientific topics. The event will include keynote events and presidential addresses of significant interest to attendees.
A recent study published in Cell Metabolism reveals a critical link between defects in the urea cycle and the development of fatty liver disease. The researchers found that these defects lead to secondary impairment in energy metabolism, resulting in excessive fat storage and inflammation in the liver.
A study by SIAT researchers found that microplastic exposure can cause intestinal damage, disrupt sleep patterns, reduce ovary size, and shorten lifespan in fruit flies. The research also revealed genotoxic effects on metabolic processes in the brain and ovary, emphasizing the urgent need to address environmental microplastic pollution.
A new study identifies three distinct profiles of preterm-born children, revealing markedly different cognitive and behavioral results. The analysis suggests that precision psychiatry can lead to more effective treatment for individual children, highlighting the complexity of preterm birth.
A new Diffusion-based Graph Contrastive Learning (DGCL) method constructs brain networks with unique features, capturing key connections and eliminating redundant ones. DGCL outperforms existing tools in terms of efficiency and prediction accuracy for brain disease analysis.
A team of researchers has created a new sonic anemometer that can track wind speeds on Mars with remarkable precision and speed. The system uses sound pulses to measure wind direction and speed in three dimensions, providing valuable insights into the Martian climate and atmosphere.
A WVU biologist is studying how genes establish animal body plans and contribute to regenerative abilities. He has identified Hox genes as key players in planarian regeneration, suggesting their functions may differ in highly regenerative versus poorly regenerative organisms.
Researchers have developed a suite of parameters that can be used to quantitatively measure different physical characteristics of the lung. The parameters were found to be highly sensitive and specific for diagnosing fibrosis and edema in an animal model, using only five necessary parameters.
Researchers at Australian National University create a new method to treat deadly diseases caused by parasites, including malaria, by attaching drugs to cholesterol. The method could lead to more effective and longer-lasting treatments, as well as implications for the agricultural industry.
The Hastings Center has received $1.5 million in funding from PCORI to develop a measure of organizational trustworthiness and investigate its role in shaping research engagement processes and outcomes. The study aims to strengthen patient-centered and stakeholder-driven comparative clinical effectiveness research.
Researchers at Heidelberg University have developed a process for producing biologically active peptide boronic acids, which could be used to induce an immune reaction against tumor cells. The new substances also show promise for targeted release of active compounds in the body.
Researchers found that targeting neutrophils' metabolic process, glycolysis, reduces NET formation and subsequent blood clots in APS patients. The strategy doesn't increase bleeding risks.
Researchers developed a framework called SigLLM that uses large language models to detect anomalies in time-series data. The approach converts time-series data into text-based inputs and can be deployed right out of the box, offering an efficient anomaly detection solution for complex systems.
Researchers have developed a new approach to enhance the stability of NiFe-based electrodes in seawater electrolysis, showcasing improved anti-corrosion properties and efficiency. The innovative W-NiFeS/WC electrode demonstrated superior activity and stability in both oxygen evolution reaction and hydrogen evolution reaction.
A recent study reviewed current research and methods used to support Australian military veterans' psychological, physical, and social well-being, highlighting the need for holistic and tailored programs. The researchers emphasize the importance of addressing social, organizational, and environmental factors alongside mental health con...
A Washington State University study reveals that automatic delivery robots with low carbon emissions can encourage consumers to use them when ordering food. Participants who were more environmentally aware and had less perceived risk of late or spoiled food were more likely to choose the robots.
A new species of the extinct genus Ontocetus, named Ontocetus posti, has been discovered in the North Atlantic. The fossil shows surprising similarities to the modern walrus, highlighting convergent evolution and adaptation to suction-feeding.
A Rice University-led team is developing an affordable system to improve tumor removal accuracy for breast and head and neck cancer. The AccessPath system enables rapid, automatic tumor margin classification, revolutionizing real-time surgical guidance.
Analysis of international longevity data reveals Australians have the best life expectancy at birth since the early 1990s, with a 4 to 5 year advantage over the US. Lower death rates from drug and alcohol misuse, screenable cancers, and cardiovascular diseases contribute to this advantage.
A nationwide cohort study of 254,670 Chinese adults aged 40-80 years reveals significant interactions between age, gender, and sleep duration on lipid levels. The study highlights the importance of considering age in studies of gender differences in metabolic diseases and advocates for personalized prevention and management strategies.
A study at the University of Helsinki discovered a new type of degenerative brain disease, limbic-predominant age-related TDP-43 encephalopathy (LATE), prevalent among the oldest old. LATE is associated with similar symptoms to early Alzheimer's but progresses more slowly and is milder.
Researchers from Sandia National Laboratories have successfully miniaturized a motion sensor using silicon photonic microchip components, achieving unprecedented accuracy and reducing size by a thousand times. This breakthrough enables precise navigation even in GPS-denied areas, posing significant national security risks.
A nationwide children's hospital implemented an automated Caring Contacts texting system to provide ongoing care and support to youth at risk for suicide. The intervention helped patients feel hopeful and supported, with 83% reporting feeling moderately to very hopeful and 88% feeling moderately to very supported.
The 2024 Europlanet Science Congress (EPSC2024) will be held in Berlin from September 8-13, covering a wide range of planetary research topics. Over 1,200 scientists from Europe and worldwide are expected to attend the fully hybrid meeting.
A recent study reveals that urban trees are more negatively impacted by heat waves and drought than their rural counterparts. The research highlights the challenges urban trees face in the context of climate change, underscoring the importance of tailored urban forestry management to protect tree species and reduce urban heat islands.
Researchers developed a faster and more precise method to separate particles in fluids, enabling quicker sorting of cells in blood samples and removal of pollutants in water. The improved technique uses specially engineered channels and high polymer concentrations to guide particles and increase accuracy.
A new study published in PLOS One found that most people view humor as an effective parenting tool, leading to improved relationships between parents and children. The research team surveyed 312 people aged 18-45 and discovered a correlation between a parent's use of humor and the quality of their relationship with their children.
Researchers found that mature trees increased wood production by an average of 9.8% under elevated CO2 levels, supporting their role as medium-term carbon stores and natural climate solutions. This increase was not accompanied by a corresponding rise in leaf or fine-root production.
A new study provides a detailed map of healthy breast cells, shedding light on how breast cancer develops and the genetic ancestry-dependent variability in breast tissue. The research aims to identify new treatment targets and improve understanding of breast cancer development.
Researchers at Florida State University have shown potential of a new treatment for pediatric brain cancer by enhancing natural killer immune cells to improve their ability to attack the disease. The study, published in Bioactive Materials, provides a critical part in addressing a major clinical need for children with brain cancer.
A mathematical model shows that quicker decisions are influenced by initial bias, while slower decisions are less biased. The model predicts that with more information, decision makers are more likely to behave rationally.
Edith Brown Weiss advocates for a Planetary Trust to ensure a just and robust Earth system for present and future generations. She proposes six critical commitments for the UN Summit of the Future, including integrating the future into decision-making and practices.
Five pioneering firms in agriculture, manufacturing, and pharma retail have demonstrated businesses can catalyze social and environmental change. They address complex issues using scientific methods, partner with NGOs, and prioritize purpose alignment.
Scientists studied multiple fossil specimens of Moschorhinus kitchingi to understand how it evolved its body structure to withstand extreme conditions. The research suggests that its robust skeleton and powerful build gave it an advantage in the late Permian period.
A new study by Umeå University found that people with type 2 diabetes have difficulty eliminating beta-amyloids, which may contribute to Alzheimer's disease. The researchers suggest that preventing or managing type 2 diabetes could reduce the risk of cognitive decline.
Researchers developed a simple, cost-effective method to study ubiquitination, a critical protein modification process involved in diverse cellular functions. The Ub-POD method quickly labels targets of E3 ligase enzymes directly in human cells, allowing for the identification of new substrates and expanding therapeutic options for dis...
Researchers at Pusan National University found compact cities reduce consumption-based carbon emissions through efficient public transportation, mixed land use, and pedestrian-friendly communities. This study supports the argument that compact city development is crucial for achieving carbon neutrality.
A national cohort study found that no routine clinical lab test can aid in diagnosing post-acute sequelae of SARS-CoV-2 infection. Ongoing inflammation is thought to contribute to symptoms like anosmia and PASC. Researchers also discovered a link between SARS-CoV-2 and diabetes risk, independent of PASC symptoms.
This comprehensive review revolutionizes the 'medicine and food homology' principle, integrating ancient dietary practices with modern living to enhance health and prevent diseases. The study's findings have profound implications for personalized nutrition, disease prevention, and treatment.
Researchers developed a learning-based approach called LVWS to schedule robots and enable voluntary waiting, resulting in faster task completion. This method outperformed other approaches by up to 23% suboptimality, demonstrating its potential to improve manufacturing, agriculture, and warehouse automation.