A global network will be created to protect Indigenous data collection and use, leveraging worldwide policies and practices to ensure control over data related to Indigenous communities. The project aims to establish an alliance among 12 Indigenous data sovereignty networks spanning the globe.
A UK cohort study reveals that even low-risk alcohol consumption is linked to increased mortality among older adults with health-related or socioeconomic risk factors. The findings suggest that healthier lifestyles may play a role in the observed attenuation of mortality for wine drinkers and those who drink only during meals.
Researchers developed a new Gd/Mn co-doped CaBi4Ti4O15 ceramic with high piezoelectric activity and Curie temperature, suitable for high-temperature applications. The optimized composition showed a high Curie temperature of 809 ℃ and a high piezoelectric coefficient of 23 pC/N.
Natural killer cells engineered to express interleukin-21 demonstrate sustained antitumor activity against glioblastoma stem cell-like cells both in vitro and in vivo. IL-21 NK cells exhibit a stronger metabolic fitness than those expressing IL-15, leading to improved tumor control.
Researchers discovered that nuclei pack strongly, ordering cells into crystalline arrays, and control tissue stiffness. The study challenges the status quo, revealing a new role for nuclei in organ formation.
A study by Florida Atlantic University researchers has identified novel players in dopamine signaling using Caenorhabditis elegans. They found that mutations in the BBSome protein complex, which regulates transport and signaling in cells, can lead to rare genetic disorders like Bardet-Biedl Syndrome.
Researchers discovered that opioid receptors in the dorsal peduncular nucleus respond uniquely to opioids, blocking aversive feelings and leading to reward. This finding contributes to the pleasurable and addictive qualities of opioids.
Researchers at UC Santa Barbara discovered that macrophages can be programmed to respond to light, triggering an increase in their appetite and improving the effectiveness of cancer immunotherapies. The findings offer a new way to enhance trained immunity, a type of memory exhibited in the innate immune system.
Researchers found high expression of OLAH linked to fatal disease outcomes, while low levels were associated with recovery. The enzyme drives severe disease through inflammatory responses and fatty acid production.
Researchers found that babies form strong expectations for a robot's responses within 10 minutes of interaction. The study suggests that contingency, or caregivers' timely reactions, is key to foundational learning in early development.
Researchers at CUNY ASRC identify distinct histone tag in adult oligodendrocyte progenitor cells that regulates their proliferation and may lead to innovative therapies for neurodegenerative diseases. The discovery holds promise for advancing myelin repair and improving patient outcomes.
Researchers developed an aspirin-containing hydrogel that mimics the nutrient-rich fluid between cells, accelerating healing of radiation-induced skin injuries in animal models. The new salve could provide rapid wound healing for humans with minimal side effects.
A new study reveals that eco-friendly activewear companies' post-consumer circular economy policies are hindered by geography, making them ineffective for global customers. The research found that many companies have take-back schemes but restrict them to domestic customers or specific locations, limiting their environmental impact.
Researchers have identified two efficient glycosyltransferases from Astragalus membranaceus, which convert medicarpin to a bioactive pterocarpan glycoside. The enzymes enable high conversion rates and have potential applications in pharmaceuticals and biotechnology.
A new study found that young people value a wide range of characteristics in computer science students, including creativity and collaboration. Intelligence is still seen as important, but the research challenges long-held stereotypes of geeky, detail-oriented men lacking social skills.
A new Australian study found a strong link between low magnesium levels and high homocysteine, leading to increased DNA damage and susceptibility to Alzheimer's, Parkinson's, gastrointestinal diseases, cancers, and diabetes. Wholegrains, dark leafy vegetables, nuts, beans, and dark chocolate are rich in magnesium.
A study by the University of Gothenburg finds that removing Fallopian tubes during laparoscopic sterilization results in marginally more surgical complications than cutting them. The procedure may help protect against future ovarian cancer, a serious disease with limited early symptoms.
The article reviews major research results on grass carp morphology, cytogenetics, molecular genetics, and germplasm resource genetic improvement. Key findings include the origin and geographical distribution of grass carp and its genetic improvement technology, including gynogenesis and hybridization techniques.
Seoul National University researchers developed a biodegradable electronic tent technology that enables non-invasive brain disease diagnosis using a needle. The device unfolds to cover the entire brain over a large area and naturally decomposes in the body after diagnosis, minimizing side effects.
Researchers detected a 24-hour cycle of diving during the spring, with whales swimming deepest in the afternoon to track prey. Two bowhead whales were found to dive in synchrony over a week at a time, even when separated by up to 100 km.
Researchers have developed a novel exosome-based drug delivery system that targets ovarian cancer cells, combining miRNA-regulated autophagy inhibition with coumarin anticancer drugs. The approach shows promising prospects for effective treatment in vitro and clinical applications.
Researchers from Tokyo Metropolitan University have discovered a fern species that can exist as an independent gametophyte for long periods without a sporophyte. This breakthrough sheds new light on the evolution of ferns and their adaptation to environmental niches.
Researchers created the first icosahedral superatomic silver nanocluster Ag13 and its gold analog Au13, exhibiting bright red luminescence. The study reveals the optical properties of these clusters and their potential applications in biological imaging.
Researchers at HKUST have developed a novel chiral-structured interface in perovskite solar cells, significantly enhancing reliability and power conversion efficiency. The new design retained 92% of its initial efficiency after 200 cycles, demonstrating improved durability under various conditions.
A team of researchers at McMaster University discovered that the epithelium plays a crucial role in directing the inflammatory response to gluten in celiac disease. They found that this inner lining of the upper intestine is not just involved in absorbing nutrients, but also activates immune cells in response to gluten.
French PDO cheese producers harbor a staggering array of microbial life in their dairy products, with over 820 bacterial species identified in the cheeses and nearly 1,230 in the milk sources. Regional artisanship plays a significant role in shaping these microbial assemblages.
Researchers at Carnegie Mellon University propose guidelines for using interpretable machine learning methods in computational biology to tackle complex problems. The guidelines address pitfalls such as relying on a single method and cherry-picking results, emphasizing the need for multiple approaches and human-centric considerations.
Researchers project significant short-term impacts of the Russian invasion on global timber markets, but also warn of long-term effects on the economy and environment. The study predicts that some product markets may not recover from the invasion, leading to increased production in other countries and potential environmental harm.
A recent study has confirmed the efficacy and safety of the dengue vaccine TAK-003, which reduces the risk of contracting the disease by over 50%. The vaccine has shown a high safety profile, with more than 90% of adults and children developing antibodies after administration.
A new study published in Frontiers in Nutrition found that a low-fat vegan diet reduces advanced glycation end-products (AGEs) by 73%, associated with an average weight loss of 13 pounds. The reduction came mainly from excluding meat, added fats, and dairy products.
Researchers at Medical University of South Carolina found that cocaine triggers a specific protein, NPAS4, which hijacks brain circuitry and promotes further drug use. Inhibiting these cells eliminates drug-seeking behavior in mice.
Researchers at the University of Chicago have discovered a new material, MnBi2Te4, that can store and access computational data using light. The material's magnetic properties change quickly and easily in response to light, making it suitable for optical storage devices.
Researchers at the University of Liverpool have achieved a significant milestone in converting carbon dioxide into valuable fuels and chemicals. They report a pioneering plasma-catalytic process for the hydrogenation of CO2 to methanol at room temperature and atmospheric pressure, achieving impressive selectivity rates.
Speech emotion recognition models are susceptible to adversarial attacks, which can significantly reduce their performance. The study found that black-box attacks outperformed white-box attacks and achieved impressive results despite limited access to the model's internal workings.
A 20-year multicenter study found improvements in gender parity and career trends among internal medicine chief residents, with a significant increase in female participation and a rise in pursuing hospital medicine careers. The study also revealed new roles such as quality improvement and patient safety chief residents.
Researchers found FoMO to be a key risk factor for employee mental health and burnout. Employees who feel overwhelmed by information and anxious about missing out experience higher levels of stress and burnout.
After two major health policy shifts, pregnant and postpartum women with depression and anxiety received slightly more psychotherapy and paid less out-of-pocket costs. Despite the positive trends, only about 10% of women with private insurance received psychotherapy in 2019 to 2020.
Researchers find undoped Spiro-OMeTAD outperforms doped devices under low-light conditions due to reduced series resistance. Devices show improved stability and reliability in these conditions, challenging the need for doping.
Researchers developed a tricot approach to collaborate with farmers in testing new crop varieties, increasing collaboration and community engagement. The approach has been shown to be cost-effective, equitable, externally valid, and scalable, benefiting national programs and improving data value.
This systematic review examines current methodologies and updates in early diagnosis practices for HNSCC, highlighting the need for effective screening methods. Effective early diagnostic practices will significantly impact patient outcomes, reducing the burden of HNSCC and enhancing quality of life.
A study published in Cell Reports found that Western classical music elicits positive effects on the brain by synchronizing neural oscillations between the auditory cortex and rewards circuit. Patients with treatment-resistant depression who received high music appreciation showed better antidepressant effects, while those with low mus...
Researchers at University of Tsukuba have achieved the first successful lab rearing of Hypselodoris festiva, revealing a previously unknown growth process. The study describes nine stages of development, from metamorphosis to adulthood, and provides a reference for further research on Chromodorididae species.
A team of researchers has discovered a gamma-ray line with an energy of up to 37 million electron volts, making it the highest-energy spectral line observed in the universe. The study used data from two space gamma-ray monitors and found that the line energy and flux evolve as a power law function of time.
Scientists at Yokohama National University successfully isolated Mannan-rich Holocellulose nanofibers (HCNFs) from spent coffee grounds using TEMPO-mediated oxidation. The resulting HCNFs exhibit desirable properties, including preservative-free long-term storage, volume reduction during transportation, and easy handling without solven...
Researchers have developed a new class of synthetic polymers that effectively combat fungal infections by attacking the cells in multiple ways. These compounds mimic naturally occurring peptides and offer potential for sustainable treatment options with improved survival rates.
Researchers unveil retrotransposon-derived DNA zip codes that enable myeloma cell internalization, shedding light on cancer evolution and treatment response. The findings highlight the potential of zip-code technology in improving patient outcomes and advancing human health.
A new classification system, PTNM, has been proposed for identifying subtypes of Peyronie's disease and penile curvature. The system, based on evidence-based criteria, identifies four distinct subtypes of PD and three non-PD categories, including congenital, maturational, and trauma-induced penile curvature.
A study by Rutgers researchers examined particulate matter from a June 2023 fire that triggered advisories for over 100 million Americans in the Northeast. The analysis revealed extremely high concentrations of ultrafine particles and toxic chemicals, surpassing national air quality standards.
Researchers highlight the need to develop new anti-angiogenic agents to improve cancer treatment efficacy, citing knowledge gaps in human clinical trials. The review recommends considering tumor mutations, microenvironment, and patient profiles to select optimal AAD combinations.
Researchers investigated the interaction and genetic introgression between two closely related spider mite species in Japan's mountains. The study found extensive overlapping distribution, hybrids, and genetic introgression, shedding light on speciation in haplodiploid organisms.
A team of researchers from the University of Arkansas has made a breakthrough in understanding species abundance by linking it to genome size. The study found that temperature and genome size are key drivers of diatom population growth rates, with body size still playing a role in colder latitudes.
A recent study by Neda Akhavan found that baked potatoes can help lower blood sugar and improve body composition in adults with Type 2 diabetes. The study, which involved 24 participants, showed a modest decrease in fasting blood glucose levels and improvements in waist circumference and resting heart rate.
Researchers uncover significant genetic and epigenetic variations in blueberries, highlighting gene introgression's role in adaptation to subtropical climates. Key genes like VcTBL44 are identified for regulating fruit firmness, offering valuable insights for future breeding programs.
Researchers have developed a novel polymer-modified Cu electrode that exhibits superior selectivity towards C2+ products, enabling efficient conversion of CO2 to fuels and chemicals. The PECA-decorated Cu electrode achieved high Faradaic efficiency (FE) values of up to 76.3% for C2+ production.
A study by Indiana University Kelley School of Business found that Black employees are more likely to attribute workplace mistreatment to racial prejudice and make a pessimistic attribution. This leads to higher rates of depression compared to white employees. Organisations must create an inclusive workplace to reduce workplace mistrea...
Researchers at Dartmouth College developed a technique using light to imprint 2D and 3D images inside any polymer containing a photosensitive chemical additive. The technology enables the creation of erasable 3D displays with high resolution, applicable in surgeries, architectural designs, education, and art.
Researchers developed a new method using spectral measurements to accurately estimate forest tree leaf nutrient content, offering a faster and larger-scale alternative to traditional methods. The method improved accuracy when accounting for soil type and tree genus, showing promise for informing forest management decisions.
A study in São Paulo state found that peer-to-peer certified organic farms had an average of 58.8 organic items, while conventionally certified farms had only 22.2. This greater diversity includes native and medicinal species, contributing to a more sustainable and biodiverse organic farming system.
Researchers found that butterflies spin unique silk structures, including hook-and-loop fasteners and multi-strand safety tethers, to secure their chrysalises to branches. Despite being thinner and weaker than silkworm silk, these structures provide a stable anchor for the butterfly's transformation.
A smartphone healthcare application was found to be more effective for weight loss among non-walkers. Participants who did not have a walking habit at baseline were more likely to achieve successful weight loss with the app, possibly due to increased physical activity triggered by notifications.