A new national standard approved by AASHTO COMP uses Purdue-developed sensor technology to provide real-time data on concrete strength, potentially saving states and contractors time and money. The method aims to reduce uncertainty in determining when concrete pavement is strong enough to handle heavy truck traffic.
Researchers found that having concerns or judgments about one's own level of happiness were associated with lower well-being, due in part to greater negativity and disappointment about positive events. Thinking too much about one's own happiness could be related to fears about not measuring up or not being as happy as other people.
The study elucidated the mechanisms behind G protein selectivity and efficacy in the human adenosine A2A receptor, discovering changes in activation conformations as the primary cause of coupling promiscuity. The research team used experimental and computational techniques to understand allosteric mechanisms and their role in selective...
Researchers identified a new enzyme XccOpgD in Xanthomonas that enhances pathogenicity, leading to potential anti-bacterial pesticides. The discovery offers sustainable solutions to global agricultural challenges and promotes environmental stewardship.
University of Utah researchers have developed a targeted therapy approach using alpha particles to break down harmful amyloid beta plaques, potentially slowing the devastating neurodegenerative disease. The treatment, called Targeted Alpha Therapy, delivers particles directly to the plaques while minimizing damage to healthy tissues.
A recent study warns that overshooting 1.5°C of global warming poses significant risks to the Earth's climate system, but swiftly reversing warming can minimize these risks. The study suggests that achieving and maintaining net-zero greenhouse gas emissions by 2100 is crucial to limit tipping risks.
Angel Martí, a professor at Rice University's Wiess School of Natural Sciences, has been elected a fellow of the American Chemical Society. He was recognized for his outstanding scientific achievements and service to the society, including leading research on Alzheimer's disease and developing new treatments.
Researchers predict that circular RNAs will play a crucial role in cancer diagnosis and treatment, enabling innovative diagnostic and therapeutic developments. The study highlights the potential of circRNAs as biomarkers, therapy targets, and even immune response inducers against cancer cells.
A new species of fossil penguin discovered in New Zealand shows how penguins' wings evolved into their present form and function. The study highlights the unique combination of bones that allowed penguins to dive and swim, contributing to their ecological diversity.
Researchers analyzed four core climate tipping elements, including the Greenland Ice Sheet and Atlantic Meridional Overturning Circulation, to determine the risks of destabilization due to overshooting 1.5°C. Achieving net-zero greenhouse gas emissions is crucial to limit tipping risks.
Researchers at Kyoto University have developed a new method to reduce optical interference and measure the quantum coherence time of moiré excitons, which are electron-hole pairs confined in moiré interference fringes. This breakthrough enables the realization of quantum functionality in next-generation nano-semiconductors.
A new study by Stellenbosch University reveals that indoor fireplaces release harmful particles into the air, posing a risk to occupant health. The research highlights the importance of improving indoor air quality in homes with amenity fireplaces.
Researchers have identified a shared genetic mechanism driving the emergence of similar traits in distantly related plants with prickles. The study reveals that mutations in a specific gene can lead to prickle loss in various species, including crops like eggplants and rice.
Researchers discovered ultrastructural abnormalities in obese patients with heart failure with preserved ejection fraction (HFpEF), which may be related to the impact of obesity on muscle structure. The study suggests that reducing obesity and using certain medications could help improve HFpEF outcomes.
Researchers at Bonn University Hospital found that increasing vegetarian options in hospital menus can encourage patients to choose healthier meals. The study involved over 2,000 participants and showed that menu design elements can influence food choices and satisfaction among meat-eaters.
A clinical trial found that fish oil supplements slowed neuronal integrity breakdown in older adults with the APOE4 gene variant, a risk factor for Alzheimer's disease. The study showed no benefit for all older adults, but suggested omega-3 fatty acids may be useful for prevention.
Researchers found that close household contacts of people diagnosed with geographically restricted TB strains had a lower rate of infection and active TB disease compared to those exposed to widespread lineages. This suggests a shared evolution between humans and microbes, amplifying the risk for infection.
A study using genomic data and artificial intelligence has revealed that the Imazighen and Arab populations of North Africa have distinct genetic origins. The research found that these two populations separated more than 20,000 years ago, shedding light on the region's complex demographic history.
Scientists analyzed rock samples from four Andes Mountains glaciers, finding they are smaller now than any time in the past 11,000 years. This suggests the tropics have already warmed beyond predicted limits, crossing a critical benchmark for glacier classification.
Researchers discovered a new type of parasitic behavior in ancient Antarctic archaea, which can kill their hosts and impact ecosystem balance. The study provides insights into these unique microorganisms' role in supporting Earth's ecosystems and holds promise for biotechnological applications.
Researchers have visualized a molecular complex that loads a 'clamp' onto DNA to ensure accurate replication. This discovery sheds light on the intricate mechanisms of DNA replication and could improve understanding of related health conditions.
A recent study published in National Science Review revealed the existence of naturally formed few-layer graphene in a lunar soil sample. The team proposes that graphene may have formed through volcanic activity and solar winds, paving the way for more affordable production methods.
Researchers discovered that transferring regenerative genes from simple organisms into fruit flies can suppress age-related issues and promote greater intestinal stem cell division. This breakthrough has implications for developing new strategies to rejuvenate stem cell function and extend healthy lifespans, particularly in humans.
Recent viral spread northward highlights unanswered questions about Oropouche virus's ecologic and pathologic characteristics. Research on the molecular virology and pathology of this arthropod-borne virus is reviewed, but crucial knowledge gaps remain.
Researchers at H. Lee Moffitt Cancer Center & Research Institute propose a unified framework for understanding antifragility in complex systems, including cancer. The study suggests that applying principles of antifragility could lead to dynamic and responsive cancer therapies.
Researchers are studying the role of stress hormones and mineralocorticoid receptors in bone health as we age. The goal is to understand how balance between these factors affects our skeletons. By investigating this complex relationship, scientists hope to develop new insights into osteoporosis and other age-related bone disorders.
Researchers found that serving a dip with a salty snack significantly increased overall energy intake, with participants consuming more calories from the combination. The study suggests that adding dip to snacks can substantially increase energy intake without people realizing it.
A new study catalogs greenhouse gas emissions tied to energy use for interbasin water transfers, with a significant portion attributed to agriculture. The research found that irrigation-related emissions are substantial in certain locations, particularly those with high concentrations of agricultural land.
A new study reveals Andean tropical glaciers are the smallest in over 11,700 years due to increasing temperatures and human-induced climate change. This region is a hot spot for understanding the cryosphere's changing state, with implications for higher-latitude glaciers.
A team of scientists from Scripps Research has developed an AI tool that can diagnose heart conditions, including heart attacks, using just three electrodes and a simpler electrocardiogram technology. The tool was tested on 238 ECGs and showed accurate clinical assessment results similar to those from original 12-lead ECGs.