A new approach using high-speed atomic force microscopy reveals distinct sEV subpopulations with specific exosome markers, enabling precise characterization and potential applications in disease diagnostics. This method has the potential to revolutionize early disease detection and targeted drug delivery.
Text2Robot leverages generative AI to convert user text descriptions into functional robots. The system generates manufacturable robot designs that resemble the specific request within minutes, making it accessible to anyone with a computer and 3D printer.
Glioblastoma, a type of brain cancer, shows resistance to traditional treatment temozolomide. Lysosomal dysfunction is linked to tumor progression and malignancy. A new approach mimicking lysine restriction may offer a promising therapeutic strategy.
A clinical trial shows that AI screening for opioid use disorder is as effective as healthcare providers in generating referrals to addiction specialists. The study found a 47% reduction in hospital readmissions among patients who received AI screening, resulting in estimated healthcare savings of nearly $109,000.
Researchers used video microscopy to explore extreme field sites on Earth, finding signs of microbial life in hot deserts, Arctic ice, and alkaline springs. The study highlights digital holographic microscopy as a tool for detecting life in space samples.
The US power system lacks capacity to handle rising demand, meeting participants agreed. Six big ideas for federal and state energy policymakers consider expanding the grid, optimizing current capabilities, and controlling costs and system reliability.
A nationwide mixed-methods approach found 85% of women deemed their science communication work as non-valuable, yet 84% continued contributing. Women often feel personally responsible for unpaid and undervalued roles.
A study led by Australian National University researchers has found that the critically endangered regent honeyeater's population decline has not been mirrored by genetic diversity loss. Despite a 99% population decrease, the species has lost only 9% of its genetic diversity due to a time-lag in genetic erosion.
Researchers found that habitually exercising retired adults outperformed sedentary peers in physical and cognitive tests. The study suggests that regular physical activity can help avoid the negative impacts of mental fatigue on cognitive and physical performance.
Dr. Leanne Redman, a leading authority on body weight regulation, has received the prestigious E.V. McCollum Award for her translational research on maternal nutrition and energy regulation, with significant impact on public health. The award recognizes her dedication to advancing research that improves women's and families' health.
Cynthia Jacelon, a renowned nurse and researcher, has developed the Jacelon Attributed Dignity Scale (JADS), a widely used concept to measure dignity in older adults. Her work focuses on rehabilitation care and promoting function in vulnerable populations.
A new Sea Grant publication provides clarity to Great Lakes fish farmers navigating permits, policies, and regulations hindering their operations. The comprehensive report breaks down complex legal frameworks, offering practical insights for understanding state and regional requirements.
Researchers have developed drug-delivering aptamers that target and kill leukemia stem cells, reducing the need for high doses of chemotherapy. The aptamers pair well with existing drugs like daunorubicin to deliver a targeted one-two knockout punch against cancer.
The updated guidelines call for uniform screening protocols in all states, recommending that IRT screening labs run twice a week and screen for all mutations known to cause cystic fibrosis. This can lead to earlier diagnosis and better treatment outcomes for newborns with the disease.
Researchers at CCNY have made a groundbreaking discovery of electronic interactions mediated via spin waves in 2D magnets. The interaction between excitons is controlled externally using a magnetic field, enabling the development of novel quantum transducers and advanced technologies.
A recent study published in Marketing Science found that 95% of influencer posts on Twitter were not disclosed, with undisclosed posts often associated with young brands and large social media followings. The study highlights a potential need for further regulatory scrutiny to ensure transparency in influencer marketing.
Lana Ruvolo Grasser, a Wayne State University assistant professor, has been selected as an Early Career Policy Ambassador (ECPA) by the Society for Neuroscience. She will engage in advocacy initiatives and learn effective strategies to advocate for scientific research and its funding.
A new study finds that the daily cycles of plant aromas shape the dietary habits and evolution of butterflies and moths. Research suggests that day-active insects have evolved to be picky eaters with larger antennae, while night-active species have more generalized diets due to reduced chemical information.
Research articles explore relative effectiveness of wildfire fuel treatments, geese impact on Arctic breeding grounds, bumble bee foraging behavior in agricultural areas, and the discovery of epiphytes in cities.
A team of researchers discovered that a robotic hand can learn to grasp and rotate objects even with incomplete or absent tactile sensation. The study highlights the importance of the sequence of learning experiences, also known as the curriculum, in facilitating learning.
Researchers at the University of Texas at Dallas have developed a durable and recyclable foam that can be 3D-printed using dynamic covalent chemistry. The new material has reversible bonds, allowing it to repair itself when damaged, making it more versatile and longer-lasting.
A study of European jackdaws reveals that sleep-deprived birds prioritize deep sleep over vigilant wakefulness. The findings suggest that even flexible sleep strategies have limits, highlighting the importance of understanding animal sleep patterns to better comprehend human sleep loss.
The study reveals that animal behavioral diversity is at risk due to declining biodiversity, which can be linked to human activities. Preserving cultural behaviors, such as tool use in primates, could aid in developing comprehensive conservation strategies.
Researchers at Rutgers University have developed an oral antiviral drug candidate that overcomes Paxlovid's limitations, providing 90% protection against SARS-CoV-2 with lower doses. The new compound, Jun13296, targets a different viral protein and works alone, addressing major side effects associated with Paxlovid.
The conference gathered international researchers to discuss AI's role in drug discovery and development, including generative AI strategies for designing chemical compounds. The speakers emphasized the significance of personalized medicine, where therapies will be tailored to each patient's unique molecular profile.
Mass General Brigham researchers have identified 17 modifiable risk factors shared by stroke, dementia, and late-life depression. Modifying any one of these risk factors can reduce the risk of all three conditions, providing an opportunity to simultaneously reduce the burden of age-related brain diseases.
This study found that low-intensity multitask exercise increased delta power during sleep and activated the prefrontal cortex immediately after the session. The findings suggest that multitasking exercise may be a promising strategy for promoting better sleep in older adults.
New research identifies specific populations of neurons in the amygdala that play a key role in regulating nutritional needs and turning them into action. The study reveals distinct groups of neurons responding to thirst and hunger, guided by molecular cues.
A new study led by NYU Langone Health scientists sheds light on how the major cancer gene BRCA2 determines which cancer cells can be killed by a class of precision cancer drugs called PARP inhibitors. Intact BRCA2 functions as a molecular shield, preventing PARP1 from disrupting DNA repair complexes, and its activity dictates PARP inhi...
The Ontario Institute for Cancer Research has announced support for five research teams developing new cancer drugs with improved efficacy and reduced side effects. The funded projects will focus on harnessing new insights about cancer biology to stop cancer from spreading and overcome treatment resistance.
A team of scientists has discovered that the circadian clock plays a crucial role in regulating F. oxysporum's response to zinc starvation and controlling secondary metabolism, enhancing its virulence. The study provides new insight into host-pathogen interactions and could lead to innovative approaches for crop protection.
A study found that pedometers capture a remarkable 88% of the health information provided by more advanced accelerometer measurements. Walking at a brisk pace is essential for cardiovascular health optimization, with a minimum cadence of 80 steps per minute strongly associated with good aerobic fitness.
A new study reveals significant shifts in prehistoric hunter-gatherer populations in Europe due to climate changes at the end of the last Ice Age. The population declined by half, but some areas in central Europe showed stability or even an increase in population size, indicating human migration towards the east.
Researchers found bonobos create complex call combinations resembling human language, suggesting compositionality is evolutionary ancient. This challenges long-held assumptions and implies a shared trait among humans and their ancestors.
A new study has revealed that Beagle dogs carrying mutations in the Shank3 gene exhibit face processing abnormalities, similar to those observed in human ASD patients. The research provides direct experimental evidence that mutations in Shank3 lead to ASD-like deficits in face processing, contributing to social impairments.
Scientists have created a new method to create silver telluride colloidal quantum dots that overcome challenges of high dark current, limited linear dynamic range, and response speed. The team developed the first proof-of-concept SWIR LIDAR using these non-toxic materials, measuring distances over 10 meters with decimetre resolution.
The Naval Research Laboratory will present emerging defense technologies, including compact coronographs and quantum navigation, at the Sea-Air-Space Conference. The NRL's hypersonic wind tunnel and Space Technologies will also be showcased.
The World Health Organization recommends universal introduction of rubella-containing vaccines into childhood vaccination programs globally. This effort will significantly boost global immunity against both diseases, bringing the world closer to eradicating them.
Researchers at MIT have developed a method to mass manufacture nanoparticles that target cancer cells, eliminating the need for manual polymer mixing and streamlining production. This approach integrates good manufacturing practice (GMP)-compliant processes, making it suitable for large-scale production of cancer treatments.
University of Queensland scientists used machine learning to predict when bacteria evolved oxygen use, finding some bacteria used it before photosynthesis. The study suggests aerobic metabolism occurred before oxygenic photosynthesis, dating back around 3.2 billion years.
Researchers at the University of Surrey developed a cost-effective method for removing CO2 from the air and converting it into synthetic fuel. The Dual-Function Material (DFM) process has been shown to be financially competitive with established industry methods, offering a promising route to decarbonize industries.
Researchers have developed a novel catalyst, ZEO-1, which exhibits high selectivity and stability in carbonylation and disproportionation reactions. The study reveals that ZEO-1's large cages promote DMM carbonylation and those in small cages favor DMM disproportionation.
A new framework helps clinicians choose phrases that more accurately reflect the likelihood of certain pathologies in X-rays, improving the reliability of critical clinical information. The approach treats certainty phrases as probability distributions, capturing nuances of what each word means.
A recent study revealed clouds are more sensitive to aerosol changes than previously thought, impacting climate warming assessments. The research findings suggest that human-induced fine particles have slowed down climate warming caused by greenhouse gases.
Researchers from Waseda University discovered that common phrasal expressions have a significant impact on how fluent speakers sound, even when controlling for smoothness and other acoustic features. This study suggests that language learners should focus on mastering everyday phrases rather than rare vocabulary to improve their fluency.
This study used high-resolution satellite data to rapidly assess coseismic surface ruptures caused by the 2023 Türkiye earthquake doublet. The research found separate rupture zones for each earthquake and highlighted seismic hazard risks for specific fault segments, including the Malatya Fault and East Anatolian Fault Zone.
Washington State University researchers develop a method to recycle wind turbine blades without harsh chemicals, recovering high-strength glass fibers and resins. The recycled materials are then reused to create stronger plastics, with enhanced performance and potential applications in various industries.
A new simulation of brain metabolism has revealed potential targets for future dementia treatments, according to a study published in Frontiers in Science. The model, available on the Open Brain Platform, could help scientists accelerate research into interventions promoting healthy brain aging.
Eventgoers use social media to capture special moments and construct narratives of their own lives, intersecting with communal narratives. This mediated memory work influences how they experience and remember live events, blurring the lines between the present and future.
A novel circular RNA, circTP63-N, generated by back-splicing exons 2–4 of the TP63 gene is significantly downregulated in nasopharyngeal carcinoma (NPC) tissues. Restoring its expression effectively inhibits NPC cell proliferation and metastasis via engagement with HSP90AB1 to modulate the YAP1/Hippo signaling pathway.
The National Comprehensive Cancer Network (NCCN) has awarded four early-career oncologists with $150,000 in funding to tackle pressing challenges in cancer care. The recipients will support studies aiming to improve cancer outcomes through molecular residual disease-guided adjuvant therapy and electronic symptom monitoring.
A longitudinal study found that individuals living in neighborhoods with low walkability had a higher risk of cardiovascular disease, even after adjusting for sociodemographic characteristics. The study highlights the importance of long-term urban planning for cardiovascular health.
Researchers have discovered a key cellular mechanism regulating mRNA vaccine delivery and stability, proposing a new paradigm for mRNA therapeutics. The study highlights the importance of N1-methylpseudouridine modification in enhancing mRNA vaccine effectiveness.
A 'master regulator' gene, ZNFX1, has been identified that may help guide treatment in patients with therapy-resistant ovarian cancer. The expression of this biomarker correlates with improved survival outcomes.
A study from Lund University found that migrating freshwater roach have larger pupils and better eyesight than non-migrating individuals. This adaptation enables them to detect small food sources in low-light conditions, crucial for survival during migration.
A national survey of 8,009 adults found that frequent exposure to gun violence is associated with increased depression, suicidal ideation, and need for mental health support. The study also highlights the importance of addressing interpersonal violence in suicide prevention efforts.
A new study found that a harmful build-up of the alpha-synuclein protein in nerve clusters near the heart may contribute to Parkinson's-related cardiac autonomic dysfunction. This suggests that targeting toxic protein clumps outside the brain could help manage symptoms and quality of life for people with Parkinson's.
A study finds that deporting undocumented immigrants working in the US healthcare system could lead to a significant shortage of skilled personnel. The loss of these workers would be particularly challenging to replace, especially if legal immigration is restricted.
The article provides actionable insights into how educators can use AI tools like ChatGPT and adaptive learning systems to enhance traditional teaching methods. The guide emphasizes the importance of implementing AI with care, ensuring that human-led education remains a priority.
The new Keck Medicine of USC – Newport Beach Radiation Oncology and Imaging Center offers biology-guided radiation therapy, using up-to-the-minute signals to track and treat cancer cells in real time. The center is equipped with state-of-the-art technology and will be the first in Orange County to provide this treatment option.