Researchers have developed a groundbreaking method to observe lysosomes in live suspended cells—quantitatively, in 3D, and without the use of chemical labels. The technology uses holographic tomography in flow cytometry configuration (HTFC) to identify morphological and spatial lysosomal changes in models of lysosomal storage diseases.
A modified rapid visual screening approach in Pakistan assesses the seismic vulnerability of buildings in high-risk areas, recommending retrofitting and strengthening measures. The study emphasizes the importance of community engagement and education to build a culture of preparedness and reduce seismic risk.
New research found microearthquakes in the central Southern Alps increase during warmer periods, triggered by meltwater from glaciers and seasonal snow. The study highlights the role of extreme rainfall and glacier dynamics in seismic activity.
A recent study published in The BMJ found that consuming three weekly servings of French fries is associated with a 20% increased risk of developing type 2 diabetes. In contrast, eating similar amounts of boiled, baked, or mashed potatoes does not substantially increase the risk. Replacing potatoes with whole grains was also linked to ...
A new study found that consuming three servings of French fries weekly increased the risk of developing type 2 diabetes by 20%. In contrast, baked, boiled, or mashed potatoes were not significantly associated with T2D risk. Swapping any form of potato for whole grains may lower the risk of T2D, with a 4% reduction in risk estimated.
Researchers from OIST and universities provided a new proof for the BBL inequality using heat and diffusion equations, taking an unconventional approach. The study offers fresh insights on the concept, which has vast applications across many fields, including computer science, medical imaging, and resource distribution.
Scientists at UChicago Pritzker Molecular Engineering have developed polymer-based nanoparticles that self-assemble at room temperature in water, enabling stable delivery of proteins and RNA. These versatile particles can be used to carry various biologic drugs, including vaccines, with high efficiency and scalability.
Elevated cdc42 activity is a critical initiation event leading to proteinuria in nephrotic syndrome. Suppression of cdc42 activity could be a promising therapy.
Researchers call for global hunt to identify 'positive tipping points' that can trigger rapid reductions in emissions and environmental harm. Experts believe a method to find these points can help accelerate the green transition.
A study of 36,000 people with high blood pressure found that taking more steps and walking faster significantly reduces the risk of major cardiovascular events. Increasing daily step count by 1,000 steps was linked to a 17% reduction in risk, with additional steps above 10,000 associated with lower risks of stroke.
A Delphi exercise with 41 therapists identified 27 statements about therapy that can improve sessions, including the importance of teamwork, outside work, and discussing concerns with loved ones. An app called EveryStep is being trialed to prepare patients for therapy, offering daily activities to aid engagement.
A University of Washington study found that biased AI chatbots can influence users' political views, with those who interacted with the most biased systems shifting their views more significantly. The researchers suggest education about AI may help mitigate this effect.
A new study published in JAMA found that the August 2023 Maui wildfire led to a 46% increase in statewide suicide and overdose death rates, with a 97% increase in Maui alone. The researchers suggest direct exposure and indirect effects, such as concern for loved ones, contributed to the rise in deaths.
A global study reveals that women's mental wellbeing and self-efficacy are key predictors of fear during childbirth. Research shows that antenatal care should focus on building women's confidence rather than just teaching coping strategies.
Researchers at Emory University developed two affordable programs to prevent youth substance misuse: Connect Kits for Family Action and Connect Brief Intervention. A randomized trial found that these programs reduced alcohol and other substance use among high school students in rural Oklahoma.
Researchers found that older adults who challenge themselves to learn new things are less likely to experience loneliness or depression, even during the COVID-19 pandemic. Continued skill learning is associated with improved mental health outcomes, including greater resilience to external stressors and reduced depressive symptoms.
A new study suggests that an AI-driven surgical education model can significantly improve the quality of resident training, reducing errors and costs. The model uses artificial intelligence algorithms and extended-reality headsets to simulate complex procedures without instructor presence.
Researchers discovered that our bodies add sugars to RNA, shielding it from the immune system. This 'sugarcoating' prevents inflammation and helps clean up dead cells.
A new Northwestern University study finds that even with renewable energy availability, switching to electric vehicles won't fight climate change without upgraded transmission grids. Targeted upgrades could alleviate congestion and unlock full emissions-reduction potential of EV adoption.
Researchers found that improving access to technology can significantly reduce healthcare disparities among African Americans. The study highlights the importance of addressing both socioeconomic disparities and technology access to achieve equity in healthcare.
A recent survey by Emory University found that Americans across party lines do not support cutting child-focused programs, such as infant safety and monitoring programs. The survey also revealed decreased trust in vaccine policy among nearly half of respondents, with concerns about lead and heavy metal contamination being the second bi...
Researchers found that AI chatbots can easily repeat and elaborate on false medical information, but a simple warning prompt can significantly reduce this risk. The study suggests that stronger safeguards are needed before these tools can be trusted in healthcare.
A recent study found that human gut evolution is closely tied to the recent surge in gastrointestinal disorders globally. The research team created human and chimpanzee intestinal organoids using stem cells, identifying key genetic differences that may have primed the human intestine for better nutrient absorption.
Researchers found that patients with Alzheimer's disease have reduced ability to absorb cholesterol from the cerebrospinal fluid, and this impairment is linked to the presence of the APOE4 variant. The study suggests that efficient delivery of cholesterol to neurons is essential for their function and maintenance.
Silvia Blemker, a renowned biomedical engineer, has been elected to lead the American Society of Biomechanics. She aims to bolster industry ties, expand funding for students and early-career researchers, and promote interdisciplinary collaboration.
USF's new program provides a defined pathway for students into high-demand field of simulation specialists, offering expertise in technical and operational aspects of simulation-based training. The program addresses a growing need for health care simulation workers to advance patient safety and care quality.
A recent University of Michigan study found that nonmedical use of prescription ADHD drugs among adolescents has dropped from 10% in 2005 to 6% in 2023. Lifetime medical use also increased slightly during the same period, but overall trends suggest a decrease in misusing these prescriptions.
Researchers found that MtABCB1 plays a crucial role in promoting arbuscule development during AM symbiosis. The protein's auxin efflux activity is essential for modulating auxin distribution and homeostasis within symbiotic cells.
The two universities are sharing high-end research equipment, including microscopes and atom probes, to foster deeper collaboration and joint research projects. This will lead to higher-quality research, faster innovation, and more effective industry engagement.
A new precision genomics initiative is launching to improve pediatric cancer diagnostics and research. The BrightSeq platform aims to deliver actionable genomic findings to care teams while accelerating research through robust sample acquisition.
Researchers found that AI-augmented, personalized feedback from human instructors enhanced surgical performance and risk management. This study suggests the integration of human expertise in AI-driven education can improve engagement and ensure contextualized, adaptive feedback.
Researchers at the Francis Crick Institute discovered that early heartbeats trigger biological signals guiding the formation of a functional beating heart in zebrafish. The study highlights the heart's ability to remodel and adapt, shedding light on congenital heart conditions.
Researchers from Guilin University of Technology developed a novel garnet-type ceramic, YMAG, exhibiting low dielectric loss, stable dielectric characteristics, and temperature stability. The material shows promise for X-Band Applications, and its optimized version achieved excellent impedance matching and high radiation efficiency.
Researchers will present findings on the risks of delirium in non-English speaking older adults and chronic pain after surgery for those experiencing food insecurity or loneliness. ANESTHESIOLOGY 2025 also explores rising fentanyl overdose deaths among older and younger adults alike.
A new study shows that higher levels of hope are linked to reduced bullying and cyberbullying, with students with more hope being less likely to engage in these behaviors. Strengthening hope could be a powerful strategy in preventing bullying by helping young people build resilience and invest in their futures.
Folate and biopterin cofactors modulate disease mechanisms through shared enzymatic pathways and structural similarities. Key interactions include BH₄ salvage, enzyme substitution, and CNS folate-biopterin axis, highlighting the importance of their crosstalk in diseases such as depression, autism, and vascular disease.
Scientists at the University of Sharjah have developed a cooling system that utilizes waste air from central air conditioning systems to cool the rear surfaces of solar panels. The system is designed to reduce energy losses caused by high operating temperatures and can recover up to 10% more solar power production.
A KAIST research team found that placental inflammation during pregnancy affects the fetus's immune system, leading to stronger allergic reactions after birth. This study presents a new possibility for early prediction and prevention of allergic diseases like pediatric asthma.
Researchers at Yonsei University have successfully measured the full quantum metric tensors of Bloch electrons in solids, a breakthrough that could lead to advanced semiconductor technologies and higher transition-temperature superconductors. The study used black phosphorus as a representative material for photoemission measurements.
The decline of seed-dispersing animals, including birds and mammals, hinders the fight against climate change by altering forest composition and reducing carbon absorption. Researchers warn that major global efforts underestimate the importance of frugivores in conservation and restoration strategies.
Research shows that warming temperatures and thawing permafrost are altering the chemistry of Arctic rivers, leading to declines in inorganic nitrogen and increases in dissolved organic nitrogen. The study highlights the importance of understanding these interconnections to protect both human health and ecosystem integrity.
Researchers at University of Pennsylvania discover red blood cells contribute to clot contraction, shrinking and stabilizing blood clots. The finding opens door to new strategies for studying and treating clotting disorders, such as excessive bleeding or dangerous clots like those seen in strokes.
A Korean survey of over 50,000 middle and high school students found that adolescent girls with weight concerns are at higher risk for depression and suicidality. The study highlights the importance of addressing body image issues in young females to prevent mental health problems.
Researchers propose a new concept, RNA immunity, which suggests small RNA molecules play a direct role in fighting viral infections in mammals. Endogenous and exogenous small RNAs can bind to viral RNA sequences and inhibit replication.
A new microscopy technique, Confocal² Spinning-Disk Image Scanning Microscopy (C²SD-ISM), has been developed to overcome limitations of existing super-resolution techniques in deep tissue environments. The system achieves high-fidelity super-resolution with a lateral resolution of 144 nm and performs 3D imaging over large volumes.
Heat-related deaths are projected to rise four-fold by 2050 if global temperatures reach 2 degrees Celsius above pre-industrial levels. Experts recommend a physiology-based approach that focuses on hot people, using tools like HeatWatch, to enhance heat adaptation and minimize carbon intensity.
Researchers create breakthrough imaging system that shows sensory activity in real time, enabling them to distinguish between different sensations. The technique uses a genetically encoded voltage sensor to observe electrical signals from neurons and has major implications for treating chronic pain and sensory disorders.
A new study from the University of Maine compares two common Atlantic sea scallop farming methods, lantern net and ear-hanging. The research found that ear-hanging production is more advantageous when scallops' life cycles exceed three years, with faster rate of production and larger adductor muscles.
Researchers have developed a method to control the interactions between light and materials at the nanoscale, allowing for ultrafast on-and-off switching of resonances. This breakthrough enables precise control over optical resonance, opening up new paths for faster optical computers, quantum communication, and photonic circuits.
Nanoparticles containing calcitriol and a protein fragment from aggrecan have been shown to regulate dendritic cell activity, reducing inflammation and swelling in RA. The treatment also delays disease onset and reduces joint damage when combined with other medications.
Researchers used large-scale simulations to reproduce near-Earth space environment, confirming opposite charge polarities between regions. Plasma motion explains the reversal in equatorial plane.
The report provides evidence-based strategies to improve communication between clinicians and patients 65 and older, addressing common barriers such as low health literacy and cognitive changes. It emphasizes adapting communication techniques to use simpler instructions and maintaining patient dignity and autonomy., A new guide from th...
Researchers at Monterey Bay Aquarium Research Institute used the EyeRIS camera system to track the movements of deep-sea pearl octopuses. The study revealed simplified control mechanisms in their arms, which could inspire the design of octopus-inspired robots.
Researchers at Boston University developed a new ultra-open metamaterial that effectively silences a broader range of unwanted sounds while preserving airflow. This breakthrough enables practical acoustic silencing in diverse settings, such as factories, offices, and public spaces.
Researchers developed a novel Ti-24Nb-4Zr-8Sn alloy with low Young's Modulus, superior corrosion resistance, and good biocompatibility. The alloy showed promising results in reducing stress shielding and improving bone regeneration compared to conventional Ti64 implants.
A cross-national study of 5,474 participants from eight European countries found that people tend to view their own population as 'victim-heroes' who resisted Nazi rule with courage. Historical records show that governments or segments of the population actively cooperated with the Nazis in many countries.
A new study suggests that genetic rescue of endangered species may not be as effective as previously thought, and could even introduce more harmful mutations. Analysis of Eastern massasauga rattlesnakes found more deleterious than adaptive mutations in donor animals selected for relocation.
Scientists have developed a new technique to silence specific genes in plants, improving crop yields and disease resistance. The vsRNAi approach uses ultra-short RNA sequences to trigger gene silencing, opening up new avenues for sustainable agriculture.
Researchers have identified a distant black hole in galaxy CAPERS-LRD-z9, dating back 13.3 billion years to the early universe. The discovery offers a unique opportunity to study the structure and evolution of this enigmatic period using cutting-edge technology like the James Webb Space Telescope.
A study by the University of Liège found that clear water ponds in Brussels emit more methane through ebullitive emissions, which are facilitated by macrophytes. This process has significant implications for global climate dynamics, as methane is a powerful greenhouse gas.