Researchers at La Trobe University's Olivia Newton-John Cancer Research Institute have developed a novel pre-clinical model expressing an enhanced version of the Cas12a enzyme, which can delete multiple genes simultaneously with high efficiency. This breakthrough enables complex genetic disorders to be modeled and interrogated.
Researchers create 3D-printed model to understand how neurons form networks and mature in neurological disorders. The nanostructured arrays guide neural network growth and directionality, influencing neuronal maturation.
Researchers developed new materials to facilitate electron transfer between enzymes and electrodes, improving biosensor performance. This innovation enables accurate measurements for disease diagnosis, environmental monitoring, and sustainable energy technology.
A new study from DTU National Food Institute finds that temperature and light intensity play a crucial role in the yield of various nutrients produced by the microalga Nannochloropsis oceanica. The research suggests a two-stage cultivation process to optimize nutrient production, paving the way for sustainable food production.
Researchers developed an AI model that analyzes electrocardiogram (ECG) data to predict biological age and potential cognitive decline. The study, based on UK Biobank data, found a link between higher ECG-age and poorer cognitive performance.
A new nanotechnology-based drug delivery system has been developed to save patients from repeated surgeries. The approach, called Pericelle, uses a paste of nanoparticles containing hydrogel on transplanted veins to prevent blockages, which can lead to repeated surgeries in heart and dialysis patients.
Professor Ashley Grossman has received the prestigious 2025 Transatlantic Alliance Award for his groundbreaking work on neuroendocrine tumors and pituitary disorders. He is recognized for fostering relationships between endocrinologists in Europe and the US, promoting collaborative efforts that advance global endocrine research.
Researchers utilized muon spin rotation spectroscopy to investigate the regioselective muoniation of peri-trifluoromethylated 12-phosphatetraphene 1, revealing a highly reactive muoniated radical at the phosphorus site. The study provided detailed insights into the structure and dynamics of the radical.
A Maynooth University study found that 84% of Parkinson's patients struggle with sleep issues, linked to depression, independent living difficulties and a decline in quality of life. Sleep problems worsen the severity of 'OFF periods' and are a significant burden on quality of life.
The TU Graz AI system optimises vehicle components using simulation models and evolutionary algorithms to reduce development time by several months. It considers multiple objectives including production costs, efficiency and package space requirements, as well as CO2 emissions across the entire supply chain.
A Mediterranean-style diet was associated with improved brain health in Hispanic/Latino adults, showing enhanced communication between brain regions and reduced white matter atrophy. The study used specialized imaging techniques to investigate the effects of diet on brain integrity.
Chalmers University researchers develop new ways to make cache memory work smarter, enabling faster data retrieval and improving computer performance. The innovation is part of the European Processor Initiative aimed at securing European independence in high-performance computing chips.
A study found that F.A.S.T. acronym was equally effective as BE-FAST in prompting people to call 911 at the first sign of stroke. However, the key stroke warning signs were remembered better with the F.A.S.T. acronym.
Researchers identified six genetic regions associated with anterior uveitis, a condition causing eye inflammation. The study also uncovered a correlation between anterior uveitis and inflammatory bowel diseases (IBD), with potential implications for treatment development.
A recent study by Ritsumeikan University researchers analyzed the durability of flexible perovskite solar cells under damp heat conditions. The findings revealed that high humidity leads to degradation, while a high-quality barrier film retained most power conversion efficiency, making it crucial for long-term stability.
Researchers synthesized optically active conducting polymers through physical methods using liquid crystals as solvents, achieving asymmetric (chiral) living polymerization. The resulting polyisocyanides exhibited optical activity and properties of twisted-bend nematic liquid crystal.
Dr. Girish N. Nadkarni, a pioneering physician-scientist, has been named Chair of the Windreich Department of Artificial Intelligence and Human Health and Director of the Hasso Plattner Institute for Digital Health at Mount Sinai. He will lead efforts to advance AI research, education, and clinical translation.
Researchers document butterfly's complete life cycle, including two distinct pupation phases, influenced by environmental conditions. The species may show phenological plasticity in response to climate change, adapting its breeding timing and brood production.
The UK's peatlands are critical ecosystems for carbon storage and biodiversity, but climate change threatens their viability. Western Scotland emerges as a priority area for conservation, while England's peatlands, including Dartmoor and the Peak District, may lose their suitability.
A new study reveals that Zika causes metabolic changes in human skin, making it a 'mosquito magnet' that attracts Aedes mosquitoes. The virus alters gene and protein expression in dermal fibroblasts, leading to increased production of volatile organic compounds that encourage mosquito bites.
A study from the University of Surrey reveals that delays in cancer diagnosis for pregnant women are often due to misattributed symptoms as normal pregnancy changes. Women experiencing more specific symptoms, such as breast lumps, are more likely to receive quicker diagnoses and referrals.
Researchers at Linköping University have developed a new technology that adds xenon to digital memories, allowing for even material coating in small cavities. This breakthrough enables more information storage in the same physical size, with 4 terabytes possible in a memory card once holding only 64 megabytes.
A new Kentucky bluegrass variety, 'Matchless', has been commercially released by Washington State University, offering higher yields and reduced environmental impact. The variety was bred to eliminate the need for field burning, a practice banned in Washington state due to air quality concerns.
A study published by the American Psychological Association found that people with higher optimism levels saved more money over time, especially those with lower incomes. Optimism was found to exert a stronger influence on savings behavior than financial literacy and risk tolerance.
A new polymer developed using gecko-inspired technology can stick to icy surfaces, reducing the risk of slips and falls. The material is designed for use in shoe soles and has potential applications in medical innovations such as electronic skin.
A new article suggests that queen conch aquaculture is not a viable solution for repopulating declining populations due to high natural mortality rates. The study recommends prioritizing protection of natural breeding aggregations and implementing proactive fisheries policies instead.
The study discovered new microbial species and never-before-reported metagenomes from African sites, shedding light on the importance of geography in shaping microbiome differences. The research highlights the need for site- and region-specific approaches to gut health interventions.
Researchers have discovered a new way to measure magnetic field orientation using tiny atom-based compasses. The technology has the potential to create precise measurement devices for various applications, including navigation, brain imaging, and medical research.
Researchers found that topical mupirocin treatment significantly lowers lesional Staphylococcus aureus levels and inflammatory signals in cutaneous lupus erythematosus lesions. The reduction in bacteria also decreases skin monocyte levels, which drive inflammation.
Research from the University of Miami found that bilingualism has a positive impact on children's executive function skills, which are crucial for daily tasks and social interactions. Multilingual children also exhibit improved perspective-taking abilities, indicating enhanced cognitive development.
A new Cochrane review confirms that antidepressants reduce anxiety symptoms in GAD patients under trial conditions. However, there is limited data on long-term usage and its potential benefits and harms.
A Chinese trial suggests that fresh embryo transfer may have a higher live birth rate than frozen embryos in women with low IVF treatment success. The study found lower rates of pregnancy and live births in the frozen group, but no differences in birth weight or complications.
Researchers found that clinicians screen for firearm access mainly when there's a risk of suicide or violence. Most clinicians underestimate the need to ask all clients about firearm access, with barriers including subjective decisions about who needs screening.
A UC Merced study revealed a significant gap in false-belief understanding among preschool children, with lower socioeconomic groups showing the most impact. Children from higher-income backgrounds showed little cognitive effect from lockdowns.
A new study found that 81% of Brazilian adolescents had experienced some form of childhood trauma by age 18, with the more types of trauma experienced increasing the risk of mental health problems. The study highlights the need for early interventions to reduce trauma exposure and mitigate its long-term consequences on mental health.
A research team from the University of Göttingen investigated the influence of the Zagros Mountains on Earth's surface bending. They found that the Neotethys oceanic plate is breaking off horizontally, creating a depression in the region.
Researchers developed a simple and sensitive optical fiber sensor for real-time detection of extremely low levels of arsenic in water. The sensor can detect arsenic levels as low as 0.09 ppb and provides analysis within just 0.5 seconds, making it a powerful tool for monitoring and ensuring safer water quality.
Researchers analyzed over 30 years of data to discover key influences on fast ice thickness in McMurdo Sound. They found that storm events, air temperature, and winter wind speed cause annual fluctuations in thickness.
A new survey from the American Heart Association reveals an increase in confidence among U.S. adults to perform lifesaving CPR during cardiac emergencies. The Nation of Lifesavers movement has contributed to this growth, with more people feeling prepared to respond in such situations.
A University of Michigan study found that people value their time similarly to the regional hourly wage when choosing between public transit and ride-hailing services like Uber and Lyft. The researchers suggest making transit more convenient could lead to larger gains in sustainability.
Researchers at the University of Pennsylvania have developed a protein called Melt that can be toggled by temperature, allowing for precise control over cellular pathways. The breakthrough enables non-invasive therapy options for cancer treatment and basic research, potentially leading to more targeted and less toxic treatments.
Researchers at Northwestern University have developed a novel high-performance organic electrochemical neuron that responds within the frequency range of human neurons. The device was integrated with artificial touch receptors and synapses to create a complete perception system, enabling real-time tactile signal sensing and processing.
A major clinical trial has identified three new safe and effective regimens for treating drug-resistant tuberculosis, offering faster, safer, and more accessible care. The new treatments show promise in reducing treatment duration and side effects, making them a significant breakthrough in the fight against this infectious disease.
Researchers found that glial cells accumulate excess extracellular matrix proteins and alter gene expression when detecting damaged cilia. This discovery may have implications for treating diseases caused by defective cilia, such as polycystic kidney disease.
A new AI-based analysis of almost 10,000 pregnancies has discovered previously unidentified combinations of risk factors linked to serious negative pregnancy outcomes. The study found that there may be up to a tenfold difference in risk for infants who are currently treated identically under clinical guidelines.
Researchers have developed a pioneering approach to predict and engineer the metalation of proteins, crucial for life. The study reveals that metal availability plays a key role in binding metals within cells, and provides practical tools to forecast metal-protein interactions.
Research from Edith Cowan University found that FIFO workers with better sleep hygiene had better health, including a better sleep environment, more regular sleep schedule, and better mental health. This includes having an optimal sleep environment despite remote mining camps' challenges.
Researchers found large pediatric centers achieve low rates of delayed diagnosis with low CT use, likely due to high-quality ultrasound capabilities. The study aims to drive diagnostic improvements by promoting adherence to best practices and coordinated care.
The partnership allows for the expansion of on-site fitness programs at senior living communities across the Boston metro area, providing access to high-quality fitness resources and preventative health programs. The Get Movin' program teaches senior residents how to improve their health through balance, mobility, cardiovascular endura...
Researchers at Rutgers University have discovered that a weekly injection of diabetes medication can replace painful daily hormone shots for people with a rare genetic form of lipodystrophy. The study found that the drug tirzepatide improved insulin resistance and normalized blood glucose levels in patients, reducing the burden and pai...
A recent study published in The Lancet Global Health found that prenatal multiple micronutrient supplements significantly reduced the risk of small vulnerable newborn types, including preterm birth, low birthweight, and small-for-gestational-age birth. These findings suggest that switching from iron and folic acid supplements to MMS as...
A University of Oklahoma researcher is exploring alternate strategies for identifying and targeting Alzheimer's and related diseases using a $2.2 million federal grant. The study aims to understand the mechanisms linking aging to cognitive decline, potentially leading to new treatments for dementia.
A new technique allows for precise tracking of tiny particles known as dark excitons in time and space. This breakthrough has the potential to improve the quality and efficiency of solar cells and other devices.
Researchers uncovered eight rare diseases that carry significantly increased risks for COVID-19-related mortality in fully vaccinated individuals. These conditions, including infertility disorders and kidney diseases, pose a nearly fivefold greater risk of death from COVID-19 than the general population.
Researchers discovered that activating NPBWR1 neurons in the central nucleus of the amygdala enhances social interactions with novel individuals. This study also found that overexpressing the human NPBWR1 gene in mouse neurons reduces sociability, highlighting the importance of genetic variations in personality traits.
Researchers at NIST have created a new thermometer using Rydberg atoms, allowing for accurate temperature measurements in fields like quantum research and industrial manufacturing. The thermometer's sensitivity could improve temperature readings by tracking energy jumps caused by blackbody radiation.
A study found that changing cholesterol levels over time is associated with a higher risk of dementia in older adults. The study suggests that fluctuating cholesterol may be a new biomarker for identifying people at risk of dementia.
A team of researchers developed an AI model called EpiBERT that can predict which genes are expressed in any type of human cell. The model accurately identified regulatory elements and their influence on gene expression across many cell types, building a 'grammar' that is generalizable and predictable.
A recent study published in Plastic and Reconstructive Surgery found that breast reduction surgery can lead to weight gain in adolescents and young women, particularly those who were at a healthy body mass index (BMI) before surgery. The study suggests that these patients should be targeted for healthy lifestyle changes to prevent weig...
A research team developed an autonomous geological assessment tool that uses machine learning to measure dip angles and directions in rock facets with high accuracy, achieving rates of up to 99.4%. The R-C-D-F method eliminates joint bands while preserving joint embedment points, making it ideal for modern infrastructure projects.