The 2026 ARDD Meeting in Boston will feature a dedicated government and regulatory panel led by senior FDA officials and ARPA-H representatives. The panel will explore how clinical trials of emerging therapeutics can be aligned with regulatory mandates and the evidence required to advance new interventions responsibly.
Researchers studied 72 young Sun-like stars and their protoplanetary disks, finding that different types of winds are more important at different stages in a planetary system's early life. The study shows that gas giants like Jupiter must assemble their massive atmospheres quickly before winds carry that raw material away.
The article introduces a field guide for environmental data scientists, providing 10 simple rules for effective use of generative AI. The rules address preparation, coding, and verification phases, aiming to fill a gap in existing advice. The guide acknowledges the environmental costs and social implications of GenAI, highlighting the ...
Researchers developed a model explaining how lava-covered worlds can maintain thick atmospheres due to molten rock sloshing over surfaces. This new theory expands the cosmic shoreline framework, suggesting a 'cosmic sandbar' region where outgassing balances escape, enabling planets to retain atmospheres.
New research proposes a revision to classical nucleation theory, revealing a gradient of crystallinity in crystal nuclei. The study uses 3D atomic imaging to examine over 8,000 nuclei in high- and medium-entropy alloys, shedding light on the energy needed for nuclei to form and merge.
The 2026 Childhood Obesity Conference, 'Be the Reason Kids Greaux Healthy,' will explore strategies for preventing and treating childhood obesity, bringing together healthcare professionals, researchers, educators, and community leaders. The conference will feature keynotes, sessions, and poster presentations on emerging topics in pedi...
Researchers develop a hybrid path-finding model for drones, finding that 2-3 rounds of adaptive planning are sufficient for optimal results. This approach balances speed and efficiency, making it practical for various applications, including search-and-rescue operations and commercial agriculture.
UCSF's new center aims to train 1,000 health care providers annually and develop screening tools to identify eating disorders. The center will also serve as a national hub for eating disorders research, connecting investigators across institutions and disciplines.
Researchers at the University of Pennsylvania School of Medicine have developed a novel scaffold system that recreates the natural transition from tendon to cartilage-like tissue to bone, promoting more organized formations of tendons, cartilage-like tissue, and bone at the repair site. This innovation aims to improve the quality and d...
Researchers at the University of Tartu developed a single genetic test that can uncover causes of previously unexplained premature ovarian insufficiency in 12% of cases. This breakthrough diagnosis provides valuable information for women with infertility and associated health risks, enabling personalized counseling and treatment options.
A $3.3 million NIH grant will support a five-year study on opioid treatment during breastfeeding, aiming to improve drug safety for lactating mothers. The researchers will develop a cell-based assay and use physiologically based pharmacokinetic models to predict drug levels in mothers and infants.
A new study finds that rain falling through wildfire smoke can deliver unusually large bursts of nitrogen, phosphorus, and potassium to ecosystems in the United States. The nutrient pulses could become an increasingly important ecological consequence of fire as wildfires become more frequent.
A new study from the University of Illinois Urbana-Champaign examines how a firstborn son impacts childbearing women's and mothers-in-law's mental health. The research found mother-in-laws experience a 15% lower risk of depression or anxiety when their daughter-in-law has a firstborn son, while daughters-in-law face increased stress as...
Researchers at the University of Maine discovered that planktonic baby lobsters preferentially feed on Calanus finmarchicus, a tiny, calorie-rich zooplankton species, during one of the most vulnerable stages of their lives. This finding is crucial to understanding fluctuations in the abundance of lobster larvae and future adult lobsters.
Liu and Xu are studying conformality-guided learning, a framework that uses conformal prediction signals during model training. They will develop theory and algorithms for three thrusts, including methods for subgroup and time-localized reliability.
Researchers at Boston Children's Hospital identified a new target responsible for bone marrow scarring in myelofibrosis, a type of blood cancer. Combining traditional therapy with drugs blocking scar formation may improve treatment outcomes. The study found that inhibiting freecycling activity with drugs like hydroxychloroquine can red...
The Rice360 project, led by Rebecca Richards-Kortum, aims to develop a low-cost, AI-enabled system to accelerate breast cancer diagnosis in rural Texas. The system, Access BreastDX, uses an AI-enabled digital microscope to quickly scan breast cell and tissue samples, providing automated assessments and remote review by pathologists.
Researchers at University of Texas MD Anderson Cancer Center found that BRAF plays a key role in developing and maintaining chronic nerve pain caused by nerve damage. Using BRAF inhibitors reduced pain sensitivity in preclinical models, suggesting therapeutic potential for treating chronic nerve pain.
Researchers discovered the world's highest late Middle Pleistocene marine deposits on the southern margin of the Central Anatolian Plateau, with deposits reaching 1177m above sea level. The findings provide a rare high-resolution temporal benchmark linking marine deposition to deep-seated geodynamic processes.
Researchers found the brain continuously blends and adjusts multiple goal-directed strategies at the same time, like a GPS system recalculating a route. The hippocampus plays an active role in tracking possible future strategies and planning upcoming actions, supporting a three-part framework for compositional control.
A tiny optical imaging probe designed for optical coherence tomography (OCT) imaging inside blood vessels in the brain has been developed. The probe can acquire full 360-degree images by using a tiny piezoelectric actuator to rotate an optical lens, eliminating rotational distortion.
A historic drought in northern Kenya led to a shift in livelihoods, with fishing becoming a crucial source of food and income among the Daasanach community. The study found that drought can alter not only physical health and food access but also cultural norms and settlement patterns, with women experiencing greater hardship than men.
Researchers at Queen Mary University of London have developed a new method for studying complex quantum systems using quantum computational spectroscopy. This approach allows for the investigation of a wider range of quantum systems, including those affected by their environment or changing over time.
Researchers from Boston Children's Hospital have developed a new gene therapy approach that collects enough stem cells in a single hospital admission, improving turnaround time for genetically altering and infusing cells. The approach has shown long-term stability and safety, with patients not experiencing any adverse effects.
Researchers at George Mason University are conducting a project to develop defense-in-depth cyber-physical security for AI data centers. The project, funded by the Virginia Innovation Partnership Authority, aims to enhance the security of AI data centers and protect against cyber-physical threats.
The University of Tennessee has been awarded a $25 million grant by the US Department of Energy to advance nuclear science and security research. The grant will support the development of new scintillators and collaboration with leading experts in nuclear non-proliferation.
A study published in PLOS Medicine suggests that global snakebite envenoming incidence is much higher than previously estimated, with 2.1-7 million cases per year and 274,000-513,000 annual deaths. Low-income countries, particularly sub-Saharan Africa, exhibit the highest incidence and mortality rates.
A study published in PLOS Medicine found that women with type 2 diabetes are more likely to develop mental health conditions, while men experience more cardiovascular and renal complications. The researchers analyzed data from 28,720 men and women in the UK, revealing significant sex differences in disease trajectories.
A large population-based study found that emergency diagnoses are common across multiple conditions, including Parkinson’s disease and coronary heart disease, and are consistently associated with worse outcomes. The study suggests that emergency diagnosis is a common phenomenon across diverse diseases and is linked to higher mortality ...
Researchers revived 160-million-year-old proteins with natural antimicrobial properties, inspiring new treatments for antibiotic-resistant infections. The revived molecules outperformed some present-day counterparts in laboratory tests, offering a promising solution to the global health issue.
Researchers developed a recyclable system using baker's yeast to store H₂ in organic molecules and iron ions to release it when needed. The method uses polyhydric alcohols and polyketones, offering a sustainable alternative to traditional H₂ production and storage methods.
A new metalens array architecture eliminates vergence-accommodation conflict and offers a wide field of view, achieving a 50° FOV 3D display. The system is highly scalable, with simulations indicating a 86° FOV limit.
Researchers found that smaller networks can be Pareto optimal, where no bank can be made better off without making another worse off. The study suggests that larger networks can lead to free-riding, reducing expected profits and market efficiency.
Researchers developed cellulose metafibers with a maximum tensile strength of 3.29 GPa and a toughness of 349.5 MJ m–3, comparable to top-tier synthetic fibers and natural spider silk. The biodegradable fibers were used in lawn and vegetation maintenance, showing wear resistance and environmental benefits.
A new evaluation framework helps bridge the lab-to-manufacturing gap for battery prelithiation technologies. The framework assesses eight prelithiation strategies across eight dimensions, enabling informed industrial technology selection.
DigBat brings together solid-state electrolyte data, simulations, machine learning, and AI to support battery materials research, providing a clearer view of the solid-state electrolyte landscape. Researchers can compare experimental and computational data, build machine-learning models, and gain insight from the data.
Researchers purified and characterized four ζ-carotene isomers, revealing UV-A shielding and antioxidant activities. The study suggests ζ-carotene's potential as a natural ingredient for skin health and photoprotection.
New research suggests that current conservation efforts are insufficient to halt the decline in common bird and butterfly species in Europe. The study projects a decline in species abundance across Europe up to 2050, with farmland birds and grassland butterflies facing strong pressures.
Researchers developed a covalently bridged interface engineering method to improve organic transistor stability, reducing leakage currents and increasing device performance. The design enables low-voltage operation and excellent charge-transport capability, making it suitable for flexible electronics applications.
FPR2 plays a pivotal role in maintaining intestinal homeostasis and promoting tissue regeneration through the PKC-ERK signaling axis. The study reveals that FPR2 activation regulates the proliferation and differentiation of intestinal stem cells and transit-amplifying cells, suggesting a potential therapeutic target for intestinal damage.
A study published in Life Metabolism reveals that high progesterone exposure during pregnancy can significantly improve menstrual cyclicity in PCOS patients and a PCOS-like mouse model. Postpartum, 60.60% of patients with irregular cycles showed improved menstrual regularity, with progesterone treatment normalizing estrous cyclicity an...
Researchers at Kumamoto University and collaborators developed a method to produce human trophoblast stem cells from late-gestation placentas, opening a new avenue for studying pregnancy complications. The resulting patient-derived models reproduce key features associated with preeclampsia, enabling the uncovering of molecular mechanis...
A new study found that fasting induces the accumulation of TCA cycle metabolites in brain lysosomes, which could support neuronal metabolic resilience. The researchers also propose three possible routes for the origin of these metabolites, including mitochondrial delivery and local interconversion supported by lysosome-associated signals.
A 10-year prospective cohort study in China found that ABC risk factors carry greater cardiovascular relevance in younger adults, while associations become less pronounced at older ages. Higher HbA1c, systolic blood pressure, and LDL-C levels were associated with increased cardiovascular risk, with varying degrees of strength across ag...
Researchers analyzed 42 pediatric ependymomas, identifying subtype-associated metabolic programs and linking them to clinical aggressiveness. The study found that the ST-YAP1 subtype had the most distinct metabolic profile, while the ST-RELA subtype was characterized by a lipid-utilizing metabolic program.
Exercise improves glucose tolerance and insulin sensitivity, restoring islet architecture and function in type 2 diabetes. The study reveals that exercise reduces inflammation and promotes a pro-inflammatory state in islet macrophages, which can compromise β-cell function.
A new PCSK9 vaccine candidate, PVC3, has been shown to induce sustained anti-PCSK9 antibodies and reduce hypercholesterolemia and atherosclerosis in mouse models. The vaccine also demonstrated a favorable preclinical safety profile, with no overt systemic toxicity or major histopathological abnormalities observed.
Endothelial CPT2 loss impairs fatty acid oxidation, promoting kidney fibrosis and renal injury. This impairment leads to reduced acetyl-CoA availability, activating an endothelial-to-mesenchymal transition (EndoMT)-like program.
Researchers identified a hierarchical nerve network in aortic perivascular adipose tissue, which is required for cold-induced blood pressure rise. Local ablation of sympathetic nerves in this tissue prevented cold-induced hypertension, underscoring its specificity.
Researchers found that ZRSR1 reduces hepatic lipogenesis and insulin resistance in mice, independently of minor intron splicing, by regulating the LXR-SREBP1c lipogenic pathway. This discovery broadens the known functions of minor-spliceosome proteins and reveals a new regulatory layer in fatty liver biology.
Researchers developed a unified scaling framework to separate quantum geometry contributions from disorder in nonlinear Hall data. The framework identified quantum-metric and Berry-curvature signals in existing second-order Hall data, allowing for clearer understanding of quantum-metric and Berry-curvature signals.
NTU Singapore's eVTOL aircraft successfully flew to heights above 90 meters and speeds of over 120 km/h, generating critical data on its performance. The aircraft demonstrated its ability to hover, fly using its fixed wings, and transition between modes, marking a milestone for Singapore's aerospace sector.
A prospective cohort study found that higher residential greenness was associated with lower type 2 diabetes risk in Chinese adults. Participants in the highest greenness tertile had a 51% lower risk of incident T2D compared to those in the lowest tertile, with the risk decreasing monotonically with increasing greenness.
Researchers found that magnetotactic bacteria AMB-1 extended lifespan by 43.39% and improved neurological function and intestinal integrity in aged worms. AMB-1 reduced iron accumulation and lipid peroxidation levels, suppressing ferroptosis and aging-related pathways.
Researchers have identified an enzyme from cow gut that can break down bacterial biofilm components, making them more vulnerable to antibiotics. The enzyme, CRhAB, was found to be effective against two notorious pathogen groups, including Acinetobacter baumannii, which poses a significant threat in healthcare settings.
Researchers propose a new AI framework, Generative Electrochemical Intelligence, to accelerate the discovery and development of electrochemical energy technologies. The framework combines generative AI with automated robotic experimentation to create a closed-loop system that can generate new ideas, test them, and learn from feedback.
Aqueous Zn-based flow batteries offer flexible design and low-cost zinc, but face issues with Zn deposition, crossover, and performance decay. Researchers call for integrated materials and reactor engineering to improve durability and energy density.
Researchers use µSR to investigate Li(Zn,Mn)As, revealing its ferromagnetic ordering and critical spin dynamics. The study provides a new understanding of the material's magnetic ground state and phase evolution.
The collaboration aims to advance molecular imaging research and develop new treatments for patients across the UK. Funded through charitable giving, the partnership brings together specialist radiopharmaceutical production and cutting-edge research, strengthening the UK's radiopharmaceutical research base.
Researchers from Zhejiang University developed a hybrid mode/wavelength division multiplexing transmitter chip using lithium niobate on insulator, achieving an aggregate capacity of 8.64 Tbps. The chip combines six modes and six wavelengths, enabling 36 independent channels with each supporting 240 Gbps transmission.