A novel silylium Lewis acid organocatalysis technology was developed, allowing for the direct installation of sulfonamide groups into ketone compounds. The catalyst enables precise control over reaction rate and substrate activation, achieving high yields in a sustainable process.
Researchers found that zirconia implants trigger an immune-inflammatory niche marked by macrophage involvement and COL6A2/CD44 signaling. In contrast, titanium implants support a regenerative microenvironment with collagenase-1/stromal-derived cell differentiation 1 (SDC1) signaling.
Researchers found that ancient hominins selected specific basalt sources for tool production, demonstrating advanced planning abilities and long-term technological traditions. This discovery highlights the ability of Acheulian hominins to plan, select, and exploit geological resources within a changing landscape.
A three-year study reveals coral hormone cycles similar to humans', helping detect reproductive stress and informing reef conservation. Hormone levels were found to be influenced by sunlight, not heat, and distributed evenly throughout colonies.
Researchers discovered that Cyanobacteria survive extreme heat through dark respiration compensating for impaired photosynthetic electron transport. A heat-tolerant strain increased respiratory activity to support energy needs when photosynthesis is weakened.
A CDC study found that most NDM-CRE cases were caused by a few high-risk strains, primarily from Klebsiella pneumoniae and Escherichia coli. The discovery of new high-risk clones highlights the importance of genomic surveillance to catch emerging threats early.
Kirigami researchers create twisty structures for flexible robotic components and soft actuators, exploiting geometrical design to enable rotation under stretching. The unique mechanical properties of these kirigami materials offer new potential applications in robotics and engineering.
A study of over 229,000 obese adults without diabetes found that weight loss drugs, such as semaglutide and tirzepatide, were associated with a 41% decrease in the overall risk of developing obesity-related cancers. GLP-1 RAs also showed larger reductions in certain subgroups, including men and gynaecologic cancers.
A new automatic detection algorithm uses AI to spot commonly-smuggled sea creatures like shark fins, seahorses, and sea cucumbers with 92% accuracy. The system integrates into 3D scanners to help identify potential shipments for investigation.
A study found that adding orfglipron to titrated insulin glargine significantly improved glycemic control and body weight in participants with type 2 diabetes. The treatment did not increase the risk of hypoglycemia, compared to placebo.
Researchers developed SpiderCam, a highly energy-efficient 3D camera inspired by jumping spiders. It captures two images with different focus settings and analyzes the differences in sharpness to produce real-time 3D maps while consuming less than a watt of power.
Mazdutide, a GLP-1 receptor dual agonist, provides clinically meaningful weight reduction in Chinese adults with obesity. However, gastrointestinal adverse reactions are more common among those taking the drug compared to placebo.
Aldebaran, a red wine made from Muscat Bailey A grapes, won a Gold Award in the Muscat Bailey A category, while Junmai -eme- received the Platinum Award in the Junmai Sake category at the French Japanese Sake Competition for the second consecutive year
A major study finds people with diabetes are at higher risk of infection, which can lead to hospitalization and death. The researchers argue that infection prevention and management should be embedded in diabetes guidelines to improve patient outcomes.
The Medicare $35 insulin out-of-pocket cap implemented in 2023 decreased and stabilized insulin out-of-pocket cost, increasing insulin use. This finding can inform policies to boost insulin access among users with high out-of-pocket cost.
Adults with both obesity and an autoimmune disease who took a GLP-1-based medication had fewer emergency department visits and lower mortality rates compared to those not taking the medication. The study analyzed data from over 26,000 adults treated in the OneFlorida+ network between 2014 and 2024.
New research links food insecurity to altered gut microbiomes in children, with potential implications for child health and development. The study found higher levels of certain bacteria, such as Sutterella, in children from food-insecure households.
A recent study assessed long-term trends in TORCH infections in a region of India with reliable data lacking. The researchers found that exposure to CMV remained constant, while immunity to rubella was consistently high. However, susceptibility to toxoplasmosis and other congenital infections persisted despite vaccination initiatives.
A new target for treating sleep apnea has been identified through a study in mice, showing that the farnesoid X receptor plays a central role in driving fatty plaque buildup during sleep apnea-like conditions. The study found that removing this receptor resulted in reduced fatty plaques and minimization of gut microbiome disruptions.
Researchers found that people living in areas with more vegetation had a wider microbial variety in their noses, correlating with better mental health scores. Time spent outside was also associated with a healthy nasal microbiome and lower depressive scores.
A new bipartisan report from Tulane University's State of the Nation Project analyzes 4,000 indicators to provide a long-term progress report for each state. The report finds significant regional divides, with Southern states ranking low on trust in institutions and Mountain states having high levels of trust but low personal well-being.
Researchers from Tokyo Metropolitan University propose a compact X-ray telescope for mapping the entire Moon surface, overcoming technical challenges that have hindered previous missions. The team's simulations demonstrate feasibility and show that it could be done in two years with five key elements.
Researchers used tissue samples, pathology images, and clinical data from 672 patients to train AI models to classify meningioma subtypes and predict recurrence risk. The findings suggest that AI can help clinicians obtain more detailed tumor information without requiring advanced genetic testing.
UChicago researchers design a setup to produce a variety of quantum states useful for ultraprecise sensing and exotic quantum materials. By breaking symmetry, they can tune the system to generate a range of different entangled states, all without changing physical components.
Researchers found that diagnosis codes captured only about one-fourth of clinically documented self-harm history, highlighting a common gap in health systems. A new study used a novel machine learning method, PULSNAR, to estimate the probability of self-harm history present but missing from diagnosis codes.
A new study presents a greener way to make slow-release fertilizers that reduce nutrient loss and improve crop growth. The tea-based fertilizer, made with iron nanoparticles, biochar, and biodegradable materials, slows down nutrient release, retains soil moisture, and improves fertilizer efficiency.
A new study found that alternate wetting and drying irrigation combined with nitrogen-loaded biochar can help rice farming address food security, water scarcity, and environmental pressure at the same time. The approach reduced water use by 14.17 to 15.56 percent while increasing rice yield by 2.23 to 5.11 percent.
A new study found that biochar can lower the temperature sensitivity of nitrous oxide emissions in agricultural soil but increase it in forest soil. Researchers tested different soils and biochar treatments and found that temperature was the dominant driver of nitrous oxide emissions, while biochar acted as a secondary modulator.
A new study by Cornell researchers explores strategies for coping with rising heat in wine grape cultivation. The team found that consumers are willing to pay a premium for wines made from heat-tolerant varieties or produced using climate-adaptive technologies, such as shade cloth.
The June 2026 nTIDE report reveals a significant increase in job-seeking among people with disabilities, signaling that more individuals are entering the labor force. The employment-to-population ratio decreased slightly for people with disabilities, while the labor force participation rate increased substantially.
Researchers propose reconsidering how histone deacetylase inhibitors work in cancer treatment, identifying genuine molecular targets as a key step to improve treatment. The study suggests that HDAC inhibitors may interfere with other proteins, suppressing cancer growth.
Researchers found that adults with developmental disabilities who used integrated psychiatric and primary care models had lower odds of presenting to emergency departments and requiring hospitalization. The study suggested that integrated care centers co-locating physical and mental health services may provide better support for this p...
The IAA SETI Committee has updated the post-detection protocols for evaluating and revealing extraterrestrial intelligence, emphasizing rigorous verification and global risk communication. The revised Declaration of Principles acknowledges the expanded search efforts and modern challenges, including protections for researchers and reco...
A new University of Arizona study has found that several common sleep behaviors may be linked to signs of brain aging. Sleeping outside the recommended seven-to-nine-hour range, frequent daytime napping, and sleeplessness were distinctly associated with greater volume of white matter lesions in healthy people.
A long-term evolutionary experiment using a self-replicating RNA-protein system resulted in evolution toward extinction. Well-mixed environments inhibited host RNA replication, leading to a decrease in concentration and loss of diversity.
Researchers at Bradley Hospital found that virtual reality (VR) training can help therapists feel more confident using exposure therapy. The study showed that simpler VR setups can be effective in reducing therapists' negative beliefs about exposure therapy.
A new UCLA study reveals that creatine supplementation significantly slows tumor growth in mice by fueling dendritic cells, a critical class of immune cells. The findings suggest that creatine may be used to enhance the immune response of patients receiving immunotherapy or improve the quality of dendritic cell-based vaccines.
A recent study suggests that entomophagy was more common in Neanderthal populations and tropical regions, while in Europe it was sporadic and accidental. The research used genomic analyses of dental calculus to reconstruct the history of insect consumption in human populations.
Researchers found that heme molecules transmit functional state of chloroplasts to the nucleus, regulating photosynthesis-related gene expression. Heme signaling is essential for plastid-derived signaling molecules, which form active phytochrome.
The Biophysical Society strongly opposes the Office of Management and Budgets' proposed rule, which centralizes control over regulations under the White House. This overhaul could have a chilling effect on scientific research, as federal agencies with subject matter expertise would lose individual oversight.
Researchers used patient-derived xenograft (PDX) models to study deadly DNA loops in cancer cells. They found significant similarities between human tumor samples and PDX models, including consistent presence of extra copies of oncogenes. These findings suggest that ecDNA-positive tumor cells may drive tumor growth and recurrence.
A University of Bristol team has developed an AI system that can automatically find, name, and follow individual animals in footage, saving thousands of hours for researchers. The system, part of the SA-FARI project, uses a foundational Vision-Language Model to precisely identify objects in images or videos.
A physicist at Mississippi State University has received a prestigious CAREER Award to study stellar explosions and their role in forming elements. The five-year project aims to improve computer models of supernovae and neutron stars, shedding light on the universe's elemental composition.
Dr. Elizabeth Kim, a researcher at Weill Cornell Medicine, has received the 2026 Tri-Institutional Breakout Award for her work on drug targeting of HCN1, an ion channel protein linked to diseases like epilepsy. Her study, published in Nature in 2024, discovered how propofol can restore mutant channels to normal function.
A study of 308 Chinese women aged 15–65 years found that women were perceived to be, on average, 1.6 years older than their actual age. Aging features such as nasolabial folds and skin evenness emerged as major determinants of age perception.
The Ipiranga Museum in São Paulo will utilize 3D laser scanning technology to create a digital model of the renovated building and establish an information management system for preventive maintenance. The project aims to analyze the behavior of the building following restoration work, identify anomalies, and prevent costly interventions.
A new handheld probe using broadband optical spectroscopy (BOS) reliably identifies early stages of necrotizing enterocolitis in premature infants. The noninvasive device measures infrared light reflecting off the intestines and detects color changes indicative of threatened tissue.
Researchers developed an AI system called OCTCube-M that can accurately identify eight different retinal diseases, including age-related macular degeneration. The technology also predicts the progression of severe forms of this condition and can infer health risks beyond the eye.
The study reveals a 250-kilometer-long linear cluster of about 1750 earthquakes marking the edge of the Yakutat microplate as it subducts beneath the North America plate. The new extent places it directly below the apex of curvature of the Alaska range and the Denali fault.
The Journal of Nuclear Medicine has published several groundbreaking studies on targeted radiotherapy approaches for various types of cancer. Researchers have successfully identified tumors using fibroblast activation protein (FAP)-targeting compounds and explored the potential of PET/MRI scans in detecting endometriosis and recurrent ...
Researchers at NINN and SOKENDAI develop a new strategy for synthesizing three-dimensional macrocycles in a square shape, featuring acid responsiveness and recyclability. The method uses an imine bond to create the shape, respond to stimuli, and revert back.
The study reveals that nearly three billion people live in areas with moderate cooling poverty, while 550 million experience severe cooling deprivation. Poor housing and weak healthcare further increase the danger of heat-related illness, particularly among outdoor workers.
Researchers discovered that supergiant deep-sea isopods have a dual survival strategy to cope with nutrient-poor conditions: an enlarged stomach for storing food and extremely low basal metabolic rate. This allows them to thrive in extreme environments.
Researchers introduce a set of universal relations that connect spectrum shapes to wave behavior in one-dimensional disordered systems. The framework reveals a never-before-seen critical state where waves localize differently depending on direction, and shows how it can be tracked using a topological winding number.
UT San Antonio's Jeff Prevost is appointed to the Texas Quantum Initiative Advisory Committee, guiding strategic investment and collaboration to advance the state's leadership in quantum research and technology development. The committee aims to develop a strategic plan supporting the growth of Texas' quantum economy.
A study led by Northwestern University identified a new biological culprit behind cognitive decline in people with HIV: the degradation of protective sugar molecules. Flu drugs preserved these sugar molecules and protected the brain in lab and mouse studies.
The Oeiras Experimenta project, a Living Lab for climate-resilient crops and sustainable food production, has won the 2026 Mariano Gago Ecsite Award. The award recognizes the collaborative work of researchers and citizens in building knowledge relevant to society.
A new approach to managing fatigue in inflammatory arthritis combines physical activity and cognitive behavioral techniques. Digital patient education is shown to be cost-effective and efficient in improving patient outcomes. Caregiver-focused interventions are also crucial in supporting daily functioning and disease management.
A multinational clinical trial found that balanced crystalloid fluid and 0.9% saline are equally safe and effective for treating septic shock in children. The study enrolled over 9,000 children and showed no difference in outcomes between the two IV fluids.
A University of Manchester astronomer led a major international effort to update the long-standing 'post-detection protocols' used in Search for Extraterrestrial Intelligence (SETI). The revised Declaration of Principles marks the first major update in over 15 years, reflecting a media landscape transformed by social media and artifici...