In a related commentary, André Vis says answers on whether PSA screening is truly beneficial at a population level will only be provided when large-scale randomized controlled trials — several of which were begun in the US and Europe in the early 1990s — are completed.
p. 586 PSA screening and prostate cancer mortality
— F. Meyer et al
p. 600 Does PSA screening reduce prostate cancer mortality?
— A.N. Vis
Canadian Medical Association Journal