Articles tagged with Cancer Screening
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new study suggests that women vaccinated against human papillomavirus (HPV) may only need cervical cancer screenings 2-3 times over a lifetime, without compromising health benefits. This approach could lead to cost-effectiveness and reduced unnecessary follow-up procedures.
Researchers have developed a four-marker panel that can detect early-stage pancreatic cancer with high accuracy, potentially improving survival rates. The new test distinguishes cancer patients from healthy individuals and those with non-cancerous conditions, such as pancreatitis.
A new liquid biopsy technology, Bridge Capture, has been developed to overcome the challenges of sensitive and cost-efficient cancer diagnostics. It detects rare variant allele frequencies with superior sensitivity compared to existing methods.
A new long-term prediction tool estimates the risk of dying from prostate cancer by combining PSA levels with factors like family history, race, age, and other health conditions. The tool showed higher accuracy in predicting prostate cancer death over decades compared to existing models.
A recent study published in Gut journal revealed that Streptococcus anginosus produces methionine metabolites, which significantly contribute to the development of gastric cancer. The research opens new paths for microbiota-targeted prevention strategies.
A new clinical trial, RECIPROCAL, seeks to optimize targeted radiation therapy for men with advanced prostate cancer by adjusting treatment based on individual PSA levels. The trial aims to minimize side effects while preserving survival benefits.
A new study has validated a non-destructive method to detect 'forever chemicals' on protective equipment, reducing the risk of cancer to firefighters. Researchers found PFAS in every set of firefighter gear examined, including breathing masks, with concentrations reaching hundreds of nanograms per gram.
A recent review suggests that Clostridioides difficile infection may promote the development of gastrointestinal tumors, including colorectal cancer. The bacterium's toxins can cause damage to the epithelial cytoskeleton and induce inflammation, leading to chronic colitis and increased risk of CRC.
A community awareness campaign in Nigeria increased awareness of colorectal cancer symptoms and risk factors, leading to earlier detection of the disease. The program also identified precancerous polyps and detected colorectal cancer at curable stages.
Researchers developed a new compact Raman imaging system that can differentiate between tumor and normal tissue, offering a promising route to earlier cancer detection. The system uses special SERS nanoparticles to detect faint signals from tumor markers, highlighting spots likely to contain tumor tissue.
The grant aims to increase individual screenings and change how health systems embed evidence-based screening practices into everyday operations. PA-CARES will work with trusted organizations in 28 counties with the lowest screening rates to implement effective screening options and facilitate timely linkage to care.
Researchers at MD Anderson have made significant discoveries in the treatment of rare bile duct cancers, with zanidatamab showing promising results. Additionally, a study identified RASH3D19 as a target to overcome treatment resistance in KRAS-mutant cancers.
Researchers have developed a simple urine test that can effectively diagnose and stage bladder cancer using cell-free DNA fragmentation analysis. The study found that specific patterns of cfDNA fragmentation can identify muscle-invasive bladder cancer with excellent specificity and predictive value.
A special issue of the Journal of the American College of Radiology highlights the transformation of lung cancer from a feared and stigmatized disease to one that is increasingly understood as chronic and treatable. Advances in screening, therapeutics, and survivorship have improved outcomes for patients.
Linda Bulone, a Queens Cancer Center Oncology nurse, received the 2025 Alliance Clinical Research Professionals Research Integrity Service Excellence (CRP RISE) Award. She has significantly increased clinical trial participation, expanded early screening efforts, and supported reductions in late-stage diagnoses.
Researchers found that fewer than 1 in 4 eligible younger adults completed colorectal cancer screenings after the USPSTF lowered the recommended screening age to 45. Despite investigating unmet social needs, no significant differences were found in testing uptake for this early midlife cohort.
A liquid biopsy test may enable early detection of various cancers, increasing stage I–III diagnoses by 10-30% and stage IV diagnoses by 45%. This could improve patient outcomes and reduce the economic impact of cancer. The study's findings suggest a game-changing approach to cancer control.
A new USC study identified five genes linked to aggressive prostate cancer in people of African descent, including ATM, BRCA2, CHEK2, HOXB13 and PALB2. The researchers developed a method combining genetic risk scores with family history and specific variant presence for personalized monitoring and treatment strategies.
A new study published in the Chinese Neurosurgical Journal explores an AI tool that identifies medulloblastoma subgroups based on magnetic resonance imaging scans. The model achieved impressive accuracy in predicting molecular subtypes and genetic risk factors, with 91% accuracy for TP53 mutations and 87% accuracy for chromosome 11 loss.
Two new studies found that 75% of adults prefer non-colonoscopy screening options like stool tests, while physicians prefer colonoscopy. Additionally, follow-up colonoscopies rose 41% after a policy change eliminated patient cost sharing for abnormal home-based stool tests.
Up to 17 million people in the US, approximately 5%, carry genetic mutations associated with cancer risk. The study highlights the importance of routine cancer screenings and suggests expanding genetic testing beyond high-risk groups.
A new national study suggests that strengthening screening programs at community-based federally qualified health centers (FQHCs) could significantly increase cervical cancer screening rates and ultimately save thousands of lives. Currently, only about 55% of women seen at FQHCs are up to date on cervical cancer screening, far below th...
Researchers at HUN-REN Szegedi Biológiai Kutatóközpont have developed an AI-powered platform for automated 3D cell culture analysis, enabling high-precision screening of cellular models. The technology removes the limitation of throughput in personalized medicine, allowing for fast and accurate analysis of clinical samples.
A comprehensive, multidisciplinary approach led to a nearly 72% lung cancer screening rate at the University of Rochester Medical Center. The program's success was attributed to collaboration among primary care and specialty teams, leveraging technology to flag eligible patients and streamline screenings.
A prospective cohort study found that increased lymphocyte counts, decreased serum LPS levels, and specific mucin expression patterns are associated with antralization. The study suggests that acid reflux is closely linked to antralization.
Researchers tested an AI-supported diagnostic method at rural hospitals in Kenya and Tanzania, analyzing cervical cell samples and human papilloma virus (HPV) samples using digital tools. The study found that the AI method worked well technically but faced challenges with inconsistent images and follow-up care.
A recent study published in Cancer Discovery found that Medicaid expansion is associated with improved five-year cause-specific and overall survival rates among cancer patients. The research showed significant improvements in survival rates for patients living in rural areas, high-poverty areas, and those with higher-mortality cancers.
Researchers found that rectal bleeding increases the odds of a colorectal cancer diagnosis by 8.5 times in patients under 50, highlighting the need for symptom-driven care and lifestyle modifications to reduce the risk. The study analyzed 443 patients and identified no family history as a factor in early-onset colorectal cancers.
A team led by Carnegie Mellon researchers has developed an innovative at-home urine test to detect over 30 types of early-stage solid tumors. The technology, combining synthetic biology and nucleic acid nanotechnology, aims to provide a precise and convenient way to screen for cancer.
A new study by Kaiser Permanente found that mailing human papillomavirus (HPV) self-sampling kits to patients increases cervical cancer screening completion rates. The study also shows that this approach is cost-effective, especially for health systems with a wide range of patient populations.
A large-scale randomized trial will examine whether AI supports radiologists in interpreting mammograms more accurately, reducing unnecessary callbacks and anxiety. The PRISM Trial, led by UCLA, aims to inform future policy decisions and best practices in breast cancer screening.
A recent study published in JAMA Network Open found that individuals with severe obesity are less likely to receive recommended cancer screenings. The research analyzed data from over 2 million US adults and discovered a significant reduction in screening rates for certain types of cancer among those with a BMI of 50.0 or greater.
Researchers increased Medicare wellness visit completion from 8.4% to 50.8% in nine months by scheduling combined visits with patients' regular clinicians, leading to lower no-show rates and increased screenings for various health issues.
A new study from the University of California - Los Angeles Health Sciences suggests that regular mammograms may still offer significant benefits for women in their 80s. The study found that screened women were more likely to have surgery to remove the tumor and had a lower risk of cancer returning and dying compared to unscreened women.
A new AI-powered deep learning model has been shown to accurately estimate the malignancy risk of lung nodules, achieving high detection rates while reducing false-positive results. The model outperformed existing probability-based tools in a retrospective study, with a relative reduction of 39.4% in false positives.
A new study finds that women who have overcome cervical cancer are nearly twice as likely to develop anal cancer compared to the general population. The study highlights the need for updated screening guidelines for these patients.
A recent study published in the Lancet Primary Care tracked over 4,800 patients referred to the SCAN Pathway, a cancer diagnosis pathway designed for patients with non-specific symptoms. The study found that early diagnosis of cancers can save thousands of lives and reduce treatment costs for the NHS.
A new liquid biopsy tool, HPV-DeepSeek, can identify HPV-associated head and neck cancer in asymptomatic individuals up to 10 years before diagnosis. The test uses whole-genome sequencing to detect microscopic fragments of HPV DNA in the blood.
Experts weighed in on the current state of artificial intelligence (AI) in cancer care, noting both its potential for improving efficiency and its challenges. Many expressed excitement over AI's possibilities for helping support an overburdened oncology workforce and accelerating the pursuit of new cures.
A randomized controlled trial found that personalized risk messages failed to increase colorectal cancer screening participation. Despite the lack of improvement, researchers emphasize the importance of continued research and potential improvements for uptake, effectiveness, and efficiency of CRC screening.
The Molecular Analysis for Precision Oncology Congress 2025 (MAP) brings together leading experts to explore the latest cancer research advances. Key topics include AI-integrated diagnostics and therapy, as well as immunotherapy and emerging developments in aging and cellular senescence.
Researchers identified three distinct molecular subtypes of follicular lymphoma, offering insights into personalized treatment plans. The subtypes C1, C2, and C3 differ in their genetic profiles and tumor microenvironments, guiding the use of specific therapies.
A new study from the University of Missouri-Columbia highlights the importance of consistent primary care coordination in cancer survivorship care. The research found that only a third of patients consistently saw the same primary care clinician during and after cancer treatment, leading to fragmented care and gaps in patient services.
A study published in The Lancet Gastroenterology & Hepatology found that routine AI assistance during colonoscopies can lead to a decrease in the ability of endoscopists to detect precancerous growths without AI aid. This reduction in skills may impact patient-related outcomes and highlight the need for further research on the long-ter...
The Lancet commission emphasizes the need for concrete goals to reduce hepatocellular carcinoma's growing disease burden. The authors propose a 2% annual reduction in age-standardized incidence rates and recommend evidence-based strategies to tackle viral hepatitis, alcohol consumption, environmental risk factors, and disparities in he...
Researchers found that automatically mailing a stool-based screening test resulted in the highest screening rates among adults aged 45-49. The study, which included over 20,000 patients, showed that this approach can encourage timely screening and potentially save lives.
Advances in endometrial cancer screening include molecular biomarkers, AI, and non-invasive diagnostics. Methylation panels show high sensitivity (>90%) and promise early detection.
Researchers at Chiba University have developed novel microfluidic devices that incorporate microcones to detect and characterize circulating tumor cells in blood. The devices demonstrated highly selective capture of human breast and lung cancer cells, with high efficiency even at high flow rates.
A study of US veterans finding that those gaining housing are more likely to undergo colorectal and breast cancer screenings. Housing is associated with increased screening rates due to improved access, reduced competing priorities, and decreased vulnerability.
A study of over 100,000 veterans found that those who secured housing were twice as likely to receive cancer screenings. This improvement in care underscores the importance of sustained investment in supportive housing and person-centered care models.
A new study suggests that offering self-collection kits during routine GP appointments can increase participation rates among women overdue for cervical screening. The approach shows promise in reducing the number of cases and saving lives.
Researchers analyzed US cancer registration systems and found disparities in racial minorities' representation, despite revisions to the established standards. The study revealed significantly lower rates for American Indian or Alaskan Native populations under the 1997 standards compared to the previous 1977 standards.
This study investigates the diagnostic performance of ATR-FTIR spectroscopy in discriminating normal breast tissue from breast tumors. The analysis reveals that specific biomarkers, particularly the cytoplasm-nucleus ratio marker, demonstrate remarkable diagnostic accuracy.
The Vanguard Study aims to understand the effectiveness and use of multi-cancer detection blood tests in detecting cancer at an early stage. Researchers will recruit adults aged 45-75 with no cancer diagnosis for five years, providing two blood samples and regular cancer screening.
A Danish study finds that HPV vaccination has reduced prevalence of high-risk HPV types among vaccinated women, suggesting population immunity. However, non-vaccine types remain common and new infections occur more frequently in vaccinated women than unvaccinated women.
Liquid biopsy-based multi-cancer early detection (MCED) offers broad population and cancer-type coverage, minimal invasiveness, and high patient compliance. However, significant challenges persist, including balancing surrogate endpoints with public health benefits, detecting early-stage cancers, and minimizing false positives.
The new NCCN Guidelines Navigator tool offers an interactive platform for accessing evidence-based guidelines, facilitating easier searching and navigation. The initiative aims to improve patient care and outcomes by providing healthcare professionals with up-to-date recommendations.
Researchers found that it took 13 years for cervical cancer screenings to halve among women over 65, and even longer for prostate cancer screenings to decrease significantly. The study emphasizes the need for more effective tracking mechanisms to identify and reduce inappropriate screening practices.
The Dresden research team developed an autonomous AI agent for precision medicine that can process multimodal data and have reasoning capabilities. The AI agent reached correct clinical conclusions in 91% of cases and accurately cited relevant oncology guidelines in over 75% of its responses.
The ESMO Gynaecological Cancers Congress 2025 will convene in Vienna, Austria, from June 19-21, featuring novel data on immunotherapy combinations and emerging treatment strategies for rare gynaecological cancers. The congress will also explore innovative approaches using antibody-drug conjugates.