Articles tagged with Cancer Screening
A prospective cohort study found that increased lymphocyte counts, decreased serum LPS levels, and specific mucin expression patterns are associated with antralization. The study suggests that acid reflux is closely linked to antralization.
Researchers tested an AI-supported diagnostic method at rural hospitals in Kenya and Tanzania, analyzing cervical cell samples and human papilloma virus (HPV) samples using digital tools. The study found that the AI method worked well technically but faced challenges with inconsistent images and follow-up care.
A recent study published in Cancer Discovery found that Medicaid expansion is associated with improved five-year cause-specific and overall survival rates among cancer patients. The research showed significant improvements in survival rates for patients living in rural areas, high-poverty areas, and those with higher-mortality cancers.
Researchers found that rectal bleeding increases the odds of a colorectal cancer diagnosis by 8.5 times in patients under 50, highlighting the need for symptom-driven care and lifestyle modifications to reduce the risk. The study analyzed 443 patients and identified no family history as a factor in early-onset colorectal cancers.
A team led by Carnegie Mellon researchers has developed an innovative at-home urine test to detect over 30 types of early-stage solid tumors. The technology, combining synthetic biology and nucleic acid nanotechnology, aims to provide a precise and convenient way to screen for cancer.
A new study by Kaiser Permanente found that mailing human papillomavirus (HPV) self-sampling kits to patients increases cervical cancer screening completion rates. The study also shows that this approach is cost-effective, especially for health systems with a wide range of patient populations.
A large-scale randomized trial will examine whether AI supports radiologists in interpreting mammograms more accurately, reducing unnecessary callbacks and anxiety. The PRISM Trial, led by UCLA, aims to inform future policy decisions and best practices in breast cancer screening.
Researchers increased Medicare wellness visit completion from 8.4% to 50.8% in nine months by scheduling combined visits with patients' regular clinicians, leading to lower no-show rates and increased screenings for various health issues.
A new study from the University of California - Los Angeles Health Sciences suggests that regular mammograms may still offer significant benefits for women in their 80s. The study found that screened women were more likely to have surgery to remove the tumor and had a lower risk of cancer returning and dying compared to unscreened women.
A recent study published in JAMA Network Open found that individuals with severe obesity are less likely to receive recommended cancer screenings. The research analyzed data from over 2 million US adults and discovered a significant reduction in screening rates for certain types of cancer among those with a BMI of 50.0 or greater.
A new AI-powered deep learning model has been shown to accurately estimate the malignancy risk of lung nodules, achieving high detection rates while reducing false-positive results. The model outperformed existing probability-based tools in a retrospective study, with a relative reduction of 39.4% in false positives.
A new study finds that women who have overcome cervical cancer are nearly twice as likely to develop anal cancer compared to the general population. The study highlights the need for updated screening guidelines for these patients.
A recent study published in the Lancet Primary Care tracked over 4,800 patients referred to the SCAN Pathway, a cancer diagnosis pathway designed for patients with non-specific symptoms. The study found that early diagnosis of cancers can save thousands of lives and reduce treatment costs for the NHS.
A new liquid biopsy tool, HPV-DeepSeek, can identify HPV-associated head and neck cancer in asymptomatic individuals up to 10 years before diagnosis. The test uses whole-genome sequencing to detect microscopic fragments of HPV DNA in the blood.
Experts weighed in on the current state of artificial intelligence (AI) in cancer care, noting both its potential for improving efficiency and its challenges. Many expressed excitement over AI's possibilities for helping support an overburdened oncology workforce and accelerating the pursuit of new cures.
A randomized controlled trial found that personalized risk messages failed to increase colorectal cancer screening participation. Despite the lack of improvement, researchers emphasize the importance of continued research and potential improvements for uptake, effectiveness, and efficiency of CRC screening.
The Molecular Analysis for Precision Oncology Congress 2025 (MAP) brings together leading experts to explore the latest cancer research advances. Key topics include AI-integrated diagnostics and therapy, as well as immunotherapy and emerging developments in aging and cellular senescence.
Researchers identified three distinct molecular subtypes of follicular lymphoma, offering insights into personalized treatment plans. The subtypes C1, C2, and C3 differ in their genetic profiles and tumor microenvironments, guiding the use of specific therapies.
A new study from the University of Missouri-Columbia highlights the importance of consistent primary care coordination in cancer survivorship care. The research found that only a third of patients consistently saw the same primary care clinician during and after cancer treatment, leading to fragmented care and gaps in patient services.
A study published in The Lancet Gastroenterology & Hepatology found that routine AI assistance during colonoscopies can lead to a decrease in the ability of endoscopists to detect precancerous growths without AI aid. This reduction in skills may impact patient-related outcomes and highlight the need for further research on the long-ter...
The Lancet commission emphasizes the need for concrete goals to reduce hepatocellular carcinoma's growing disease burden. The authors propose a 2% annual reduction in age-standardized incidence rates and recommend evidence-based strategies to tackle viral hepatitis, alcohol consumption, environmental risk factors, and disparities in he...
Researchers found that automatically mailing a stool-based screening test resulted in the highest screening rates among adults aged 45-49. The study, which included over 20,000 patients, showed that this approach can encourage timely screening and potentially save lives.
Advances in endometrial cancer screening include molecular biomarkers, AI, and non-invasive diagnostics. Methylation panels show high sensitivity (>90%) and promise early detection.
Researchers at Chiba University have developed novel microfluidic devices that incorporate microcones to detect and characterize circulating tumor cells in blood. The devices demonstrated highly selective capture of human breast and lung cancer cells, with high efficiency even at high flow rates.
A study of over 100,000 veterans found that those who secured housing were twice as likely to receive cancer screenings. This improvement in care underscores the importance of sustained investment in supportive housing and person-centered care models.
A new study suggests that offering self-collection kits during routine GP appointments can increase participation rates among women overdue for cervical screening. The approach shows promise in reducing the number of cases and saving lives.
A study of US veterans finding that those gaining housing are more likely to undergo colorectal and breast cancer screenings. Housing is associated with increased screening rates due to improved access, reduced competing priorities, and decreased vulnerability.
Researchers analyzed US cancer registration systems and found disparities in racial minorities' representation, despite revisions to the established standards. The study revealed significantly lower rates for American Indian or Alaskan Native populations under the 1997 standards compared to the previous 1977 standards.
This study investigates the diagnostic performance of ATR-FTIR spectroscopy in discriminating normal breast tissue from breast tumors. The analysis reveals that specific biomarkers, particularly the cytoplasm-nucleus ratio marker, demonstrate remarkable diagnostic accuracy.
The Vanguard Study aims to understand the effectiveness and use of multi-cancer detection blood tests in detecting cancer at an early stage. Researchers will recruit adults aged 45-75 with no cancer diagnosis for five years, providing two blood samples and regular cancer screening.
A Danish study finds that HPV vaccination has reduced prevalence of high-risk HPV types among vaccinated women, suggesting population immunity. However, non-vaccine types remain common and new infections occur more frequently in vaccinated women than unvaccinated women.
Liquid biopsy-based multi-cancer early detection (MCED) offers broad population and cancer-type coverage, minimal invasiveness, and high patient compliance. However, significant challenges persist, including balancing surrogate endpoints with public health benefits, detecting early-stage cancers, and minimizing false positives.
The new NCCN Guidelines Navigator tool offers an interactive platform for accessing evidence-based guidelines, facilitating easier searching and navigation. The initiative aims to improve patient care and outcomes by providing healthcare professionals with up-to-date recommendations.
Researchers found that it took 13 years for cervical cancer screenings to halve among women over 65, and even longer for prostate cancer screenings to decrease significantly. The study emphasizes the need for more effective tracking mechanisms to identify and reduce inappropriate screening practices.
The Dresden research team developed an autonomous AI agent for precision medicine that can process multimodal data and have reasoning capabilities. The AI agent reached correct clinical conclusions in 91% of cases and accurately cited relevant oncology guidelines in over 75% of its responses.
The ESMO Gynaecological Cancers Congress 2025 will convene in Vienna, Austria, from June 19-21, featuring novel data on immunotherapy combinations and emerging treatment strategies for rare gynaecological cancers. The congress will also explore innovative approaches using antibody-drug conjugates.
Researchers validate new at-home cervical cancer screening device, the Teal Wand, as a safe and effective alternative to traditional in-clinic screenings. The device detects precancer 96% of the time, detecting HPV-related cells that may develop into cancer.
Researchers identified C5aR1 as a novel prognostic biomarker and potential therapeutic target for treating metastatic skin cancer. Elevated C5aR1 presence suggests increased metastasis risk and poor survival in patients with cutaneous squamous cell carcinoma.
Tumors exploit lipid metabolism to evade immune surveillance and manipulate the tumor microenvironment. Lipid metabolism-related molecules serve as potential biomarkers for early cancer detection and guide diagnosis, prognosis, and treatment decisions.
The University of Houston has launched a $3M Cancer Immunotherapy Biomarker Core to accelerate early diagnosis and treatment response in cancer. The core will offer comprehensive targeted proteomic cancer biomarker screens, enabling researchers to identify better biomarkers for cancer.
A randomized controlled trial found that additional imaging techniques such as fast MRI and contrast mammography can detect early-stage cancers in women with dense breasts that were missed by mammograms. The study showed a cancer detection rate of 1.7% for fast MRI and 1.9% for contrast mammography, compared to 0.4% for ultrasound.
A new liquid biopsy blood test called HPV-DeepSeek achieved 99% sensitivity and specificity for diagnosing cancer in asymptomatic patients. The test detected fragments of the viral genome and other features in the blood, outperforming current methods in detecting HPV-associated head and neck cancers.
Researchers identified changes in stromal tissue associated with increased aggressive breast cancer risk and poorer survival rates among women with benign breast disease. The study used machine learning to detect subtle changes in breast tissue samples from over 9,000 women.
Research finds that multitarget stool DNA tests have higher sensitivity than FIT, but are not as cost-effective for early detection of colorectal cancer. Costs per detected advanced neoplasia case or early-detected CRC case are 7- to 9-fold higher for MSDT-based and N-G MSDT-based screening.
The NCCN Policy Summit brought together experts to discuss ways to strengthen collaborative cancer care, from early detection to survivorship. Key findings include the need for better communication and coordination between primary care and oncology providers.
Researchers found AI outperformed physicians in answering GI cancer questions, with oncologists preferring ChatGPT's responses nearly 80% of the time. Additionally, fewer patients are getting surgery for benign colon polyps as endoscopic techniques rise, reducing serious complications and mortality rates.
Anal cancer is increasing rapidly among older, white and Hispanic women due to HPV vaccination delays. The study found a significant increase in anal cancer rates for these groups, reaching 11.4 cases per 100,000 in 2021.
A recent study found that early-stage stomach cancer diagnoses are increasing, marking a major progress in detecting this deadliest form of cancer. The study suggests advancements in endoscopic imaging and more widespread use of upper endoscopy may be contributing to these shifts.
A cross-sectional study found that state-level tax policies were associated with increased cancer screening rates and reduced mortality rates, with these benefits mainly extending to white populations. The researchers suggest that state-level policies may contribute to closing gaps in cancer care.
Pennington Biomedical welcomes Dr. Adithya Hari, MD, with expertise in nuclear oncology and translational science, strengthening cancer research and patient-centered innovation in Louisiana. He will establish a research program focused on nuclear medicine and dedicate time to direct patient care through a clinical partnership.
A study found that most head-and-neck cancer survivors who underwent radiation don't know about survivorship care, despite grapple with side effects such as dry mouth, swallowing problems, and psychological distress. The survey also found that 40% of survivors still struggle with dry mouth and nearly a quarter reported trouble swallowing.
A non-risk-based lung cancer screening approach using low-dose computed tomography (LDCT) in Chinese populations detects a significant number of early-stage lung cancers. The study found that incorporating non-high-risk individuals into screening programs can lead to a greater detection rate and improved patient outcomes.
A predictive model combining tumor marker readings with patients' genetic profiles enhances predictions for patient survival and surgery decision-making. The new tool accurately identifies candidates who would benefit from surgery, suggesting that current tumor marker evaluations are inadequate for these genetic profiles.
A 20-year initiative that offered flexible screening options at a major health system doubled screening rates and cut cancer incidence by a third, halving deaths. The program eliminated racial disparities in outcomes, with Black patients' deaths declining from 52.2 to 23.5 per 100,000.
Liquid biopsy analyzes circulating tumor components in body fluids to detect cancer at early stages, offering a safer and more dynamic alternative to traditional tissue biopsies. This non-invasive approach has shown promise in detecting various types of cancer, including lung, breast, colorectal, prostate, and gastric cancers.
Research highlights the oncogenic potential of microRNAs in lung cancer, their dysregulation, and functional roles. Dysregulated miRNAs can contribute to tumor progression, metastasis, and chemotherapy resistance.
A survey of patients who underwent breast cancer screening mammograms found most support AI's role as a second reader, but concerns about data privacy and bias persisted. Demographic factors such as education and racial background played a significant role in shaping patient perceptions of AI.
A cohort study found that women with screen-detected estrogen receptor–positive or human epidermal growth factor receptor 2–negative breast cancer who underwent prior screening had an earlier stage of diagnosis and lower breast cancer mortality compared to those who did not undergo prior screening.
A recent analysis found that rates of colorectal cancer diagnoses dropped during Hurricanes Irma and Maria and the COVID-19 pandemic in Puerto Rico, but late-stage diagnoses eventually exceeded expectations. Limited access to cancer screening services due to these disasters likely hindered timely CRC diagnoses.
A new method uses pulsed infrared light to analyze molecular patterns in blood plasma, potentially identifying cancer-specific 'fingerprints'. The technique showed accuracy of up to 81% in detecting lung cancer and differentiating it from control samples.