Articles tagged with Cancer Screening
Advances in endometrial cancer screening include molecular biomarkers, AI, and non-invasive diagnostics. Methylation panels show high sensitivity (>90%) and promise early detection.
Researchers at Chiba University have developed novel microfluidic devices that incorporate microcones to detect and characterize circulating tumor cells in blood. The devices demonstrated highly selective capture of human breast and lung cancer cells, with high efficiency even at high flow rates.
A study of US veterans finding that those gaining housing are more likely to undergo colorectal and breast cancer screenings. Housing is associated with increased screening rates due to improved access, reduced competing priorities, and decreased vulnerability.
A study of over 100,000 veterans found that those who secured housing were twice as likely to receive cancer screenings. This improvement in care underscores the importance of sustained investment in supportive housing and person-centered care models.
A new study suggests that offering self-collection kits during routine GP appointments can increase participation rates among women overdue for cervical screening. The approach shows promise in reducing the number of cases and saving lives.
Researchers analyzed US cancer registration systems and found disparities in racial minorities' representation, despite revisions to the established standards. The study revealed significantly lower rates for American Indian or Alaskan Native populations under the 1997 standards compared to the previous 1977 standards.
This study investigates the diagnostic performance of ATR-FTIR spectroscopy in discriminating normal breast tissue from breast tumors. The analysis reveals that specific biomarkers, particularly the cytoplasm-nucleus ratio marker, demonstrate remarkable diagnostic accuracy.
The Vanguard Study aims to understand the effectiveness and use of multi-cancer detection blood tests in detecting cancer at an early stage. Researchers will recruit adults aged 45-75 with no cancer diagnosis for five years, providing two blood samples and regular cancer screening.
A Danish study finds that HPV vaccination has reduced prevalence of high-risk HPV types among vaccinated women, suggesting population immunity. However, non-vaccine types remain common and new infections occur more frequently in vaccinated women than unvaccinated women.
Liquid biopsy-based multi-cancer early detection (MCED) offers broad population and cancer-type coverage, minimal invasiveness, and high patient compliance. However, significant challenges persist, including balancing surrogate endpoints with public health benefits, detecting early-stage cancers, and minimizing false positives.
The new NCCN Guidelines Navigator tool offers an interactive platform for accessing evidence-based guidelines, facilitating easier searching and navigation. The initiative aims to improve patient care and outcomes by providing healthcare professionals with up-to-date recommendations.
Researchers found that it took 13 years for cervical cancer screenings to halve among women over 65, and even longer for prostate cancer screenings to decrease significantly. The study emphasizes the need for more effective tracking mechanisms to identify and reduce inappropriate screening practices.
The Dresden research team developed an autonomous AI agent for precision medicine that can process multimodal data and have reasoning capabilities. The AI agent reached correct clinical conclusions in 91% of cases and accurately cited relevant oncology guidelines in over 75% of its responses.
The ESMO Gynaecological Cancers Congress 2025 will convene in Vienna, Austria, from June 19-21, featuring novel data on immunotherapy combinations and emerging treatment strategies for rare gynaecological cancers. The congress will also explore innovative approaches using antibody-drug conjugates.
Researchers validate new at-home cervical cancer screening device, the Teal Wand, as a safe and effective alternative to traditional in-clinic screenings. The device detects precancer 96% of the time, detecting HPV-related cells that may develop into cancer.
Researchers identified C5aR1 as a novel prognostic biomarker and potential therapeutic target for treating metastatic skin cancer. Elevated C5aR1 presence suggests increased metastasis risk and poor survival in patients with cutaneous squamous cell carcinoma.
The University of Houston has launched a $3M Cancer Immunotherapy Biomarker Core to accelerate early diagnosis and treatment response in cancer. The core will offer comprehensive targeted proteomic cancer biomarker screens, enabling researchers to identify better biomarkers for cancer.
Tumors exploit lipid metabolism to evade immune surveillance and manipulate the tumor microenvironment. Lipid metabolism-related molecules serve as potential biomarkers for early cancer detection and guide diagnosis, prognosis, and treatment decisions.
A randomized controlled trial found that additional imaging techniques such as fast MRI and contrast mammography can detect early-stage cancers in women with dense breasts that were missed by mammograms. The study showed a cancer detection rate of 1.7% for fast MRI and 1.9% for contrast mammography, compared to 0.4% for ultrasound.
A new liquid biopsy blood test called HPV-DeepSeek achieved 99% sensitivity and specificity for diagnosing cancer in asymptomatic patients. The test detected fragments of the viral genome and other features in the blood, outperforming current methods in detecting HPV-associated head and neck cancers.
Researchers identified changes in stromal tissue associated with increased aggressive breast cancer risk and poorer survival rates among women with benign breast disease. The study used machine learning to detect subtle changes in breast tissue samples from over 9,000 women.
Research finds that multitarget stool DNA tests have higher sensitivity than FIT, but are not as cost-effective for early detection of colorectal cancer. Costs per detected advanced neoplasia case or early-detected CRC case are 7- to 9-fold higher for MSDT-based and N-G MSDT-based screening.
The NCCN Policy Summit brought together experts to discuss ways to strengthen collaborative cancer care, from early detection to survivorship. Key findings include the need for better communication and coordination between primary care and oncology providers.
Researchers found AI outperformed physicians in answering GI cancer questions, with oncologists preferring ChatGPT's responses nearly 80% of the time. Additionally, fewer patients are getting surgery for benign colon polyps as endoscopic techniques rise, reducing serious complications and mortality rates.
A recent study found that early-stage stomach cancer diagnoses are increasing, marking a major progress in detecting this deadliest form of cancer. The study suggests advancements in endoscopic imaging and more widespread use of upper endoscopy may be contributing to these shifts.
Anal cancer is increasing rapidly among older, white and Hispanic women due to HPV vaccination delays. The study found a significant increase in anal cancer rates for these groups, reaching 11.4 cases per 100,000 in 2021.
A cross-sectional study found that state-level tax policies were associated with increased cancer screening rates and reduced mortality rates, with these benefits mainly extending to white populations. The researchers suggest that state-level policies may contribute to closing gaps in cancer care.
Pennington Biomedical welcomes Dr. Adithya Hari, MD, with expertise in nuclear oncology and translational science, strengthening cancer research and patient-centered innovation in Louisiana. He will establish a research program focused on nuclear medicine and dedicate time to direct patient care through a clinical partnership.
A study found that most head-and-neck cancer survivors who underwent radiation don't know about survivorship care, despite grapple with side effects such as dry mouth, swallowing problems, and psychological distress. The survey also found that 40% of survivors still struggle with dry mouth and nearly a quarter reported trouble swallowing.
A non-risk-based lung cancer screening approach using low-dose computed tomography (LDCT) in Chinese populations detects a significant number of early-stage lung cancers. The study found that incorporating non-high-risk individuals into screening programs can lead to a greater detection rate and improved patient outcomes.
A predictive model combining tumor marker readings with patients' genetic profiles enhances predictions for patient survival and surgery decision-making. The new tool accurately identifies candidates who would benefit from surgery, suggesting that current tumor marker evaluations are inadequate for these genetic profiles.
A 20-year initiative that offered flexible screening options at a major health system doubled screening rates and cut cancer incidence by a third, halving deaths. The program eliminated racial disparities in outcomes, with Black patients' deaths declining from 52.2 to 23.5 per 100,000.
Liquid biopsy analyzes circulating tumor components in body fluids to detect cancer at early stages, offering a safer and more dynamic alternative to traditional tissue biopsies. This non-invasive approach has shown promise in detecting various types of cancer, including lung, breast, colorectal, prostate, and gastric cancers.
A survey of patients who underwent breast cancer screening mammograms found most support AI's role as a second reader, but concerns about data privacy and bias persisted. Demographic factors such as education and racial background played a significant role in shaping patient perceptions of AI.
Research highlights the oncogenic potential of microRNAs in lung cancer, their dysregulation, and functional roles. Dysregulated miRNAs can contribute to tumor progression, metastasis, and chemotherapy resistance.
A cohort study found that women with screen-detected estrogen receptor–positive or human epidermal growth factor receptor 2–negative breast cancer who underwent prior screening had an earlier stage of diagnosis and lower breast cancer mortality compared to those who did not undergo prior screening.
A recent analysis found that rates of colorectal cancer diagnoses dropped during Hurricanes Irma and Maria and the COVID-19 pandemic in Puerto Rico, but late-stage diagnoses eventually exceeded expectations. Limited access to cancer screening services due to these disasters likely hindered timely CRC diagnoses.
A new method uses pulsed infrared light to analyze molecular patterns in blood plasma, potentially identifying cancer-specific 'fingerprints'. The technique showed accuracy of up to 81% in detecting lung cancer and differentiating it from control samples.
Researchers at George Mason University have developed AI models that can predict cancer risk with accuracy rates of up to 90% for certain types of cancer. These models can enable risk-based screening recommendations, increasing access to life-saving cancer detection for high-risk patients.
A new study by Mass General Brigham researchers reveals that many eligible patients who receive other preventative screenings are not getting screened for lung cancer. The study found that 65% of those eligible received breast and colorectal cancer screening, a nearly 4-fold higher rate than lung cancer screening.
Dr. Schoenborn's pioneering research focuses on bridging the gap between common concepts and patient perspectives to deliver personalized care. Her work aims to improve cancer screening, deprescribing medications, and using artificial intelligence in geriatric medicine.
A study found that patient navigators significantly improved one-year follow-up colonoscopy completion rates by 12% and reduced time to follow-up by 27 days. The researchers emphasize the importance of timely follow-up colonoscopies for patients with abnormal stool test results.
A new study found that interval cancers, which are detected between two screening sessions, account for 30% of all breast cancers. Women with high breast density, hormone therapy, and a family history of breast cancer are at increased risk. More frequent or improved screening methods could significantly improve early detection rates.
Recent studies by Regenstrief Institute and Indiana University School of Medicine found a sharp decline in colorectal cancer screening trends during the pandemic, followed by a rapid rebound. The impact was more pronounced on non-invasive testing, such as fecal immunochemical tests (FIT) and FIT/DNA tests, which declined but recovered ...
The national healthcare initiative has been extended for five years to provide world-class healthcare services to every Guyanese citizen. The partnership will establish a national cancer center, modernize national health facilities, and implement an advanced digital health system.
New leukemia treatment combination shows promise for patients with follicular lymphoma. Immunotherapy research also explores ways to suppress protein ZNF638 to boost effectiveness of immune checkpoint inhibitors. Innovative funding efforts support Sylvester's cancer research initiatives.
The updated guidelines substantially increased lung cancer screenings overall, but disparities persist among people with limited access to healthcare. Barriers include cost, knowledge, and lack of primary care providers, with mobile units and patient navigators offering potential solutions.
A sub-analysis of 20-year follow-up data from the European Randomized study of Screening for Prostate Cancer (ERSPC) reveals that men who consistently decline prostate cancer screening appointments have a 45% higher risk of dying from the disease compared to those who attend screening appointments.
A deep learning model analyzes breast arterial calcification and translates results into a cardiovascular risk score, helping identify patients at higher risk of heart disease. The tool is particularly useful for younger women, who can benefit from early interventions.
A multicenter cohort study found that higher adherence to annual lung cancer screening was associated with increased overall and early-stage lung cancer detection rates. However, adherence decreased over time, suggesting it is a critical quality metric for lung cancer screening.
Researchers at the University of Texas at El Paso have developed a portable, blood-based device that can detect colon cancer using a biomarker called CCSP-2. The device has the potential to provide early detection and treatment options for this second-deadliest US cancer, making it a significant advancement in colorectal cancer screening.
The project aims to enhance CTC detection sensitivity and specificity for clinical needs in cancer early screening, diagnosis and treatment. The team will develop an integrated system covering CTC counting, classification and downstream detection of CTC proteins and genes.
Genalive wins largest outsourced testing service contract in Saudi Arabia's history, covering 83 public hospitals and multiple genomics methodologies. The deal will enhance local precision medicine services with comprehensive solutions for whole genome sequencing, exome sequencing, and more.
Recent research suggests that some invasive cancers diagnosed in early-stage breast cancer may not need immediate surgery, highlighting the importance of more precise screening methods for DCIS. The COMET trial found that at least half of invasive breast cancers take years to progress or may never progress at all.
Breast cancer death rates are predicted to increase in EU patients aged 80 years and older, while falling in all other age groups. This is attributed to a lack of regular screening and access to modern treatments.
Researchers found that women who received text message reminders were twice as likely to get their cervical cancer screenings within 150 days compared to those without reminders. The study suggests a promising low-cost approach to increasing cancer screenings in underserved populations.
Breast cancer mortality rates have stopped decreasing in two age groups: women under 40 and those over 74. This shift is attributed to an increase in stage IV breast cancers at diagnosis, leading to poor prognoses.
A risk prediction model was developed to identify patients unlikely to complete HPV vaccination. The model uses patient demographics and clinical characteristics to guide targeted interventions, increasing vaccination rates among high-risk groups.
Breast and colorectal cancer screening rates have recovered from pandemic-related declines, surpassing pre-pandemic estimates. Cervical cancer screening rates remain below pre-pandemic levels, indicating a persistent trend of declining early-stage diagnoses.
Research from Radboud University Medical Center found that people with intellectual disabilities are significantly less likely to participate in cancer screenings for cervical, breast, and colon cancer. The results highlight the need for better alignment of screening programs with the needs of individuals with intellectual disabilities.