Cancer Screening
Articles tagged with Cancer Screening
Rice researchers develop realistic ‘mock’ samples to speed cervical cancer test development
A team of Rice University bioengineers has developed a new way to create highly realistic mock patient samples that could help accelerate the development of faster and more accessible cervical cancer screening tests. The approach combines multiple factors, including viral DNA levels and cell counts, to mimic real clinical specimens.
Psychological factors sustaining gastric cancer screening during the COVID-19 pandemic
Cancer-detecting breakthrough earns Scott national ‘American Innovator’ recognition
Colleen Scott's patented research develops a shortwave infrared dye to visualize cancer cells, enabling safe and high-resolution deep tissue visualization. Her technology selectively targets cancer cells, allowing clinicians to identify tumor boundaries with greater precision.
Single screening sigmoidoscopy linked to lower colorectal cancer risk two decades later
Researchers found a sustained reduction in colorectal cancer incidence and death associated with single flexible sigmoidoscopy screening, particularly in men. The study suggests that this screening method can provide long-lasting benefits beyond the usual 15-year screening age range.
ERASur colorectal cancer trial reaches one-third patient accrual milestone
The ERASur clinical trial is investigating whether total ablative therapy can improve overall survival in patients with newly diagnosed, limited metastatic colorectal cancer. The study has reached one-third patient accrual milestone, signaling strong momentum.
Trial now enrolling seeks to answer key question: Does adding chemotherapy to hormone therapy improve survival for metastatic prostate cancer?
The ASPIRE trial aims to enroll 1,200 participants with advanced prostate cancer and assess the impact of chemotherapy on overall survival and disease progression. Genetic profiling is included to identify patients who benefit most from intensified treatment.
Retrieval-augmented AI may improve accuracy and trust in oncology applications
The review highlights how retrieval-augmented generation can improve the accuracy, transparency, and clinical reliability of AI tools in cancer care. RAG-enhanced systems produced more accurate results than standard AI models across multiple studies.
Survey finds many women still believe mammograms should start at age 50—experts say age 40
A new survey found that nearly half of women incorrectly believe annual mammograms should start at age 50. Experts recommend yearly mammograms starting at age 40 for average-risk women. This delay can lead to cancers being found at a later stage, when treatment can be more complex.
The benefits of prostate cancer screening outweigh the harms, according to new patient guidelines from NCCN
The new NCCN Guidelines for Patients: Prostate Cancer Screening provide a comprehensive guide to evidence-based recommendations for age-specific screening. The guidelines aim to balance the benefits of early detection with the risks of unnecessary procedures, emphasizing the importance of personalized care and monitoring.
Mail-in test for colorectal cancer could help community health centers increase screening
Researchers found that a newer stool-based screening test, FIT-DNA, increased completion rates among participants from community health centers. However, follow-up colonoscopy tests remained low, highlighting the need for continued support and access to diagnostic services.
Prostate cancer overdiagnosis rises sharply with age
A new study found that prostate cancer overdiagnosis increases with age, with low rates in younger men and high rates in older men. The study suggests that targeted PSA testing or screening policies for men in their 50s and early 60s may be more effective.
Alliance study shows new promise against locally advanced lung cancer
A study by the Alliance Foundation Trials shows that combining immunotherapy and chemotherapy before surgery can help more patients with locally advanced non-small cell lung cancer undergo complete cancer resection, improving their long-term health. The treatment also led to high rates of lymph node clearance and successful surgical re...
Primary breast tumors already harbor cells with metastatic potential
Researchers have identified the Prrx1 gene as a key regulator of metastatic potential in breast cancer tumors. This discovery helps explain why highly invasive cells do not always give rise to metastases, and how cells combine invasiveness and proliferation to become the most dangerous from a clinical perspective.
Colorectal cancer and mortality risk among older adults with vs without adenoma on prior colonoscopy
Adults aged 75 or older without adenoma on prior colonoscopy have lower risk of subsequent colorectal cancer and CRC death. Despite this, those with prior adenoma may consider deprioritizing surveillance colonoscopy relative to other health concerns.
Colorectal cancer screening and health-related social needs in a national sample of US adults
A national study found that unmet health-related social needs are associated with lower colorectal cancer screening rates, particularly among adults aged 50-64. Addressing these needs may support age-specific strategies to improve screening rates.
AACR: Targeted drug delivery for colorectal cancer, COVID-19’s impact on breast cancer outcomes, AI in cancer diagnosis and more
UCLA investigators present new research on targeted drug delivery for colorectal cancer, COVID-19's impact on breast cancer outcomes, and AI in cancer diagnosis. These studies offer insights into overcoming drug resistance, enhancing immune responses, and improving outcomes for patients with difficult-to-treat cancers.
JMIR Publications showcases precision oncology success: individualized multi-drug therapy outperforms standard care
A new article in JMIR Publications showcases precision oncology's success, where individualized multi-drug regimens improve treatment responses and survival rates for patients with advanced cancers. The study found that closely matching drug therapies to tumor mutations leads to better outcomes, while also offering a safer profile.
UCLA researchers develop low-cost blood test to detect multiple cancers and other diseases from a single sample
A new, cost-effective blood test detects liver, lung, ovarian, stomach cancers, and various non-cancer conditions by analyzing DNA fragments in the bloodstream. The test achieved high accuracy rates for multi-cancer detection and tissue-of-origin identification.
Women with diabetes less likely to receive preventive care and some screenings
A recent study published in the Journal of General Internal Medicine found that women with diabetes are less likely to receive recommended preventive care services such as conception counseling and breast/cervical cancer screening. This oversight puts them at risk for preventable medical conditions like pregnancy complications.
Population-based lung cancer screening can reduce mortality in people who have never smoked, study shows in China
A new study in China finds that onetime lowdose computed tomography (LDCT) screening can significantly reduce lung cancer mortality in a non–risk based population, including individuals with no smoking history. The findings support reconsideration of current eligibility criteria.
Early results from a trial of active surveillance for low-risk DCIS are ‘reassuring’
Researchers have reported early, reassuring results from the LORD trial on active surveillance for low-risk DCIS. The study found that patients with active surveillance did not experience worse early outcomes compared to those who underwent immediate surgery, and that many chose active surveillance over surgery.
Blood test may improve survival of childhood cancer in Africa
A minimally invasive liquid biopsy test has been shown to diagnose Burkitt lymphoma rapidly and accurately in sub-Saharan Africa, where delays in traditional testing often prove fatal. The test achieved an overall accuracy of 98% and reduced the time needed to reach a diagnosis by 40 days on average.
Prostate cancer screening as good as breast cancer screening, say researchers
Researchers compare prostate cancer screening to breast cancer screening, finding similarities in identifying significant cancers and reducing mortality. The study suggests that prostate cancer screening should be reconsidered, offering benefits over harms, and highlights the need for further analysis on costs.
Scan that makes prostate cancer cells glow could cut need for biopsies
A new imaging test, PSMA PET/CT scan, has been shown to safely reduce the number of biopsies needed for suspected prostate cancer, with no harm to patients. The PRIMARY2 trial found that the scan could identify low-risk patients who did not need a biopsy, while targeting suspicious areas for those who did.
Research presented at international urology conference in London shows how far prostate cancer screening has come
Research presented at EAU26 confirms that prostate cancer screening leads to a reduction in mortality, but also detects cancers that would otherwise remain undetected. The study's findings suggest that using MRI in prostate cancer screening can reduce overdiagnosis and unnecessary biopsies.
Severe COVID-19, flu facilitate lung cancer months or years later, new research shows
Severe COVID-19 and influenza infections can prime the lungs for cancer development, according to new research. Vaccination, however, largely prevents these changes, suggesting a reduced risk of lung cancer.
$10 million gift establishes the King Center for Lynch Syndrome at Penn Medicine
The King Center for Lynch Syndrome will advance research, outreach, education, and patient care for Lynch syndrome, a hereditary condition affecting 1 in 279 individuals. The center will provide cutting-edge research, life-long comprehensive care, and increased awareness for patients and families affected by Lynch syndrome.
AI cancer tools risk “shortcut learning” rather than detecting true biology
New research warns that popular AI systems for predicting cancer biology may rely on visual shortcuts, raising concerns about their reliability for real-world patient care. Despite achieving high accuracy, these models often fail when conditions change or confounding factors are controlled.
Renowned cancer physician and researcher Dr. Daniela Matei to lead Houston Methodist Neal Cancer Center
Renowned cancer clinician Dr. Daniela Matei will lead the Houston Methodist Dr. Mary and Ron Neal Cancer Center, bringing expertise in ovarian cancer treatment and therapeutics. She aims to bridge laboratory science to the clinic, advancing new concepts from bench to bedside.
Performance of the APCS-SDC2 score based on a fecal SDC2 methylation assay for the detection of colorectal polyps
A new fecal SDC2 methylation assay, combined with the Asia-Pacific Colorectal Screening Scoring (APCS), demonstrates superior performance in detecting advanced adenomas and stratifying risk. The test's high specificity makes it a valuable tool for prioritizing colonoscopy.
AI-boosted electronic nose detects ovarian cancer
Researchers at Linköping University have developed an AI-boosted electronic nose that can detect ovarian cancer from blood plasma samples with high accuracy. The method uses machine learning to identify patterns specific to the disease, making it a promising tool for early detection and improved survival rates.
Screening improves early detection of colorectal cancer
Researchers found that both screening methods lead to more cases of early-stage cancer being detected, especially in the first two years. The study suggests that screening may have a preventive effect by removing precursors to cancer.
Telehealth improves access to genetic services for adult survivors of childhood cancers
A recent clinical trial found that remote telehealth services increased the uptake of genetic counseling and testing in adult survivors of childhood cancers. The study showed a significant impact on reducing morbidity and mortality by driving earlier detection of subsequent cancer.
Call for action on understudied lung cancer in never-smokers
A new review highlights the growing burden of lung cancer in never-smokers, emphasizing the need for dedicated research, screening, and clinical trials. The study argues that LCINS has distinct causes and biology requiring a different approach to diagnosis and treatment.
Half of all men over 60 have prostate cancer – an AI diagnostic tool could identify which need followup
A new AI-powered analysis tool called PROVIZ is being tested in Norwegian hospitals to diagnose prostate cancer. The tool helps doctors determine which patients need a biopsy, reducing the number of unnecessary procedures.
Study suggests far fewer cervical cancer screenings are needed for HPV‑vaccinated women
A new study suggests that women vaccinated against human papillomavirus (HPV) may only need cervical cancer screenings 2-3 times over a lifetime, without compromising health benefits. This approach could lead to cost-effectiveness and reduced unnecessary follow-up procedures.
Researchers identify new blood markers that may detect early pancreatic cancer
Researchers have developed a four-marker panel that can detect early-stage pancreatic cancer with high accuracy, potentially improving survival rates. The new test distinguishes cancer patients from healthy individuals and those with non-cancerous conditions, such as pancreatitis.
Novel liquid biopsy technology lowers barriers for more efficient cancer diagnostics
A new liquid biopsy technology, Bridge Capture, has been developed to overcome the challenges of sensitive and cost-efficient cancer diagnostics. It detects rare variant allele frequencies with superior sensitivity compared to existing methods.
New model improves prediction of prostate cancer death risk
A new long-term prediction tool estimates the risk of dying from prostate cancer by combining PSA levels with factors like family history, race, age, and other health conditions. The tool showed higher accuracy in predicting prostate cancer death over decades compared to existing models.
New evidence reveals streptococcus anginosus drives gastric cancer development
A recent study published in Gut journal revealed that Streptococcus anginosus produces methionine metabolites, which significantly contribute to the development of gastric cancer. The research opens new paths for microbiota-targeted prevention strategies.
New prostate cancer trial seeks to reduce toxicity without sacrificing efficacy
A new clinical trial, RECIPROCAL, seeks to optimize targeted radiation therapy for men with advanced prostate cancer by adjusting treatment based on individual PSA levels. The trial aims to minimize side effects while preserving survival benefits.
Study: Simple wipe test finds invisible cancer-linked PFAs on firefighter gear
A new study has validated a non-destructive method to detect 'forever chemicals' on protective equipment, reducing the risk of cancer to firefighters. Researchers found PFAS in every set of firefighter gear examined, including breathing masks, with concentrations reaching hundreds of nanograms per gram.
Can community awareness campaigns in low-resource areas improve early diagnosis of colorectal cancer?
A community awareness campaign in Nigeria increased awareness of colorectal cancer symptoms and risk factors, leading to earlier detection of the disease. The program also identified precancerous polyps and detected colorectal cancer at curable stages.
Clostridioides difficile: A suspected pro-carcinogenic bacterium for gastrointestinal tumors
A recent review suggests that Clostridioides difficile infection may promote the development of gastrointestinal tumors, including colorectal cancer. The bacterium's toxins can cause damage to the epithelial cytoskeleton and induce inflammation, leading to chronic colitis and increased risk of CRC.
New Raman imaging system detects subtle tumor signals
Researchers developed a new compact Raman imaging system that can differentiate between tumor and normal tissue, offering a promising route to earlier cancer detection. The system uses special SERS nanoparticles to detect faint signals from tumor markers, highlighting spots likely to contain tumor tissue.
$4.2M CDC grant to increase colorectal cancer screening in Pennsylvania
The grant aims to increase individual screenings and change how health systems embed evidence-based screening practices into everyday operations. PA-CARES will work with trusted organizations in 28 counties with the lowest screening rates to implement effective screening options and facilitate timely linkage to care.
MD Anderson shares latest research breakthroughs
Researchers at MD Anderson have made significant discoveries in the treatment of rare bile duct cancers, with zanidatamab showing promising results. Additionally, a study identified RASH3D19 as a target to overcome treatment resistance in KRAS-mutant cancers.
A simple urine test could revolutionize bladder cancer diagnosis and treatment
Researchers have developed a simple urine test that can effectively diagnose and stage bladder cancer using cell-free DNA fragmentation analysis. The study found that specific patterns of cfDNA fragmentation can identify muscle-invasive bladder cancer with excellent specificity and predictive value.
“Lung cancer should no longer be defined by fear and stigma,” experts say
A special issue of the Journal of the American College of Radiology highlights the transformation of lung cancer from a feared and stigmatized disease to one that is increasingly understood as chronic and treatable. Advances in screening, therapeutics, and survivorship have improved outcomes for patients.
Queens Cancer Center Oncology nurse receives Alliance CRP RISE Award for Advancing Cancer Research
Linda Bulone, a Queens Cancer Center Oncology nurse, received the 2025 Alliance Clinical Research Professionals Research Integrity Service Excellence (CRP RISE) Award. She has significantly increased clinical trial participation, expanded early screening efforts, and supported reductions in late-stage diagnoses.
Colorectal cancer screenings remain low for people ages 45 to 49 despite guideline change
Researchers found that fewer than 1 in 4 eligible younger adults completed colorectal cancer screenings after the USPSTF lowered the recommended screening age to 45. Despite investigating unmet social needs, no significant differences were found in testing uptake for this early midlife cohort.
Could a liquid biopsy test lead to earlier diagnoses for numerous cancer types?
A liquid biopsy test may enable early detection of various cancers, increasing stage I–III diagnoses by 10-30% and stage IV diagnoses by 45%. This could improve patient outcomes and reduce the economic impact of cancer. The study's findings suggest a game-changing approach to cancer control.
Chinese Neurosurgical Journal study explores AI tool to predict medulloblastoma subtypes and genetic risks with high accuracy
A new study published in the Chinese Neurosurgical Journal explores an AI tool that identifies medulloblastoma subgroups based on magnetic resonance imaging scans. The model achieved impressive accuracy in predicting molecular subtypes and genetic risk factors, with 91% accuracy for TP53 mutations and 87% accuracy for chromosome 11 loss.
New USC study identifies key genes linked to aggressive prostate cancer in people of African descent
A new USC study identified five genes linked to aggressive prostate cancer in people of African descent, including ATM, BRCA2, CHEK2, HOXB13 and PALB2. The researchers developed a method combining genetic risk scores with family history and specific variant presence for personalized monitoring and treatment strategies.
As millions lag in colon cancer screening, new studies point to strategies to boost uptake and follow-up
Two new studies found that 75% of adults prefer non-colonoscopy screening options like stool tests, while physicians prefer colonoscopy. Additionally, follow-up colonoscopies rose 41% after a policy change eliminated patient cost sharing for abnormal home-based stool tests.
New Cleveland Clinic research finds up to 5% of Americans carry genetic mutations associated with cancer risk
Up to 17 million people in the US, approximately 5%, carry genetic mutations associated with cancer risk. The study highlights the importance of routine cancer screenings and suggests expanding genetic testing beyond high-risk groups.
Federally qualified health centers could boost cervical cancer screening
A new national study suggests that strengthening screening programs at community-based federally qualified health centers (FQHCs) could significantly increase cervical cancer screening rates and ultimately save thousands of lives. Currently, only about 55% of women seen at FQHCs are up to date on cervical cancer screening, far below th...
Szeged researchers accelerate personalized medicine with AI-powered 3D cell analysis
Researchers at HUN-REN Szegedi Biológiai Kutatóközpont have developed an AI-powered platform for automated 3D cell culture analysis, enabling high-precision screening of cellular models. The technology removes the limitation of throughput in personalized medicine, allowing for fast and accurate analysis of clinical samples.
How to double lung cancer screening rates
A comprehensive, multidisciplinary approach led to a nearly 72% lung cancer screening rate at the University of Rochester Medical Center. The program's success was attributed to collaboration among primary care and specialty teams, leveraging technology to flag eligible patients and streamline screenings.