Articles tagged with Cancer Screening
A new study by City of Hope and TGen found large differences in mutation rates between healthy individuals and cancer patients. The study suggests that individuals who accumulate mutations at a higher rate are more likely to develop cancer.
The UVA Weber Symposium will discuss the latest research and advancements in metastasis, a complex area of cancer research and care. The event will bring together top scientists and physicians to present findings on cancer metastasis, genetics, and treatment considerations.
The PATHFINDER 2 study found that adding a blood test to standard screening increased cancer detection 6.5-fold, identifying cancers with no routine screening options. The test demonstrated a high specificity and low false-positive rate, making it a powerful complement to standard screening.
A machine learning system has been developed to identify cancer cells based on their light scattering patterns, achieving high accuracy even with cells having similar morphology. The system, which uses dark-field microscopy and machine learning algorithms, has shown promise in distinguishing between different types of cancer cells.
The SUNY Technology Accelerator Fund is providing grants to support research in AI, energy-efficient semiconductors, and non-invasive monitoring. Five campuses will receive funding for projects that could improve cancer diagnostics, circadian rhythm disorders, and burn diagnostics.
A new study reanalysed data from eight randomised trials on mammography screening, finding overdiagnosis to be less than 5%. The researchers suggest that previous high estimates of overdiagnosis were based on incomplete evidence and taken out of context.
A study published in JAMA Network Open reveals that nearly 1 in 3 women in their 20s have never been screened for cervical cancer, with 45% of this age group unvaccinated against HPV. The trend is particularly concerning among uninsured women, those living in the South, and racial minorities.
A nationally representative survey reveals that more than 4 in 10 US adults reporting childhood abuse are less likely to attend breast and cervical screenings. This disparity underscores the importance of trauma-informed healthcare approaches to improve cancer screening rates among survivors.
A review published in the journal CANCER reveals that cost-effective interventions such as single-dose HPV vaccination, screen-and-treat strategies, and workforce development can substantially improve outcomes in low- and middle-income countries. These interventions can bridge the survival gap between LMICs and wealthier nations.
A new study found that the majority of veterans with low-risk prostate cancer pursued active surveillance in 2024, up from 27% in 2005. The study followed over 73,000 veterans and showed similar survival outcomes for surveillance compared to treatment.
Recent research found that D-serine accelerates gastric cancer growth by suppressing cytotoxic T-cell activity and promoting immunosuppressive macrophages. High serum D-serine concentrations were linked to ICI therapy resistance in patients, suggesting its potential as a biomarker for disease progression.
Dr. Amoako's evidence-driven services improve early diagnosis, expand access to treatment, and advance locally led research in Ghana. Her work aims to strengthen childhood cancer care across the country.
The Alliance QUANTUM trial is testing whether post-transplant consolidation therapy with teclistamab improves survival in patients with primary plasma cell leukemia. Plasma cell leukemia is a rare but aggressive blood cancer with poor long-term survival rates.
Circulating circRNAs show high cell-type and tissue specificity, making them ideal for non-invasive cancer management. They can be detected in multiple body fluids and reflect treatment response, positioning them as functional drivers of therapy resistance.
A Rutgers-led study of nearly 500,000 adults reveals that repeat testing is linked to earlier diagnoses and depends on primary care provider behaviors. The study found that health systems play a significant role in increasing patient consistency, with Kaiser Permanente having the highest adherence rate.
A new study from MUSC suggests that combining flexible testing options and community partnerships can bring populationwide genomic screening to rural and socially vulnerable communities. Over 50,000 adults have completed screening through In Our DNA SC, a program that has reached participants in all 46 South Carolina counties.
A study revealed persistent disparities in cancer care for LGBTQ+ populations, particularly transgender individuals, who face significant challenges accessing breast and cervical cancer screenings. The research highlights the urgent need for targeted interventions to bridge these gaps and ensure equitable care.
Researchers estimate that relabeling Grade Group 1 prostate cancer as a precancerous condition could reduce unnecessary treatment and prevent nearly 2,400 prostate cancer deaths annually. This change may encourage more men to get screened, potentially leading to fewer deaths from aggressive prostate cancer.
A multidisciplinary panel of experts recommends evidence-based screening and surveillance strategies for pancreatic cancer in high-risk populations, aiming to improve early diagnosis and survival. The guidelines specify starting ages, surveillance intervals, imaging modalities, surgical indications, and lifestyle modifications.
This review highlights the regulatory roles of m6A in colorectal cancer, integrating oncogenic signaling and metabolic pathways. Key regulators include METTL3, METTL14, FTO, ALKBH5, and IGF2BP families, which control tumor growth, metastasis, immune evasion, and therapy resistance.
The University of Texas at San Antonio Health Science Center has received a grant from the American Cancer Society to implement HPV self-collection in primary care settings. The pilot aims to make cervical cancer screening more accessible for patients who face barriers to traditional screening.
Researchers identified specific gene mutations and characteristics associated with early-onset breast cancer in young Black women. The study highlights the importance of genetic testing for this population, which faces lower screening rates than other groups.
A pilot study of the Participant Engagement Portal (PEP) tool shows that 84% of participants had a positive experience, with high usability and satisfaction rates. PEP facilitates two-way communication between patients and clinicians, allowing for self-reporting of social risk factors and future research opportunities.
A recent study found that melanoma disproportionately affects Florida's senior population, with older men experiencing twice as many skin cancer-related deaths as women. The study highlights gaps in prevention and early detection, particularly among men and non-Hispanic populations.
A comprehensive review of breast cancer risk models in women with a family history found that none are highly accurate at identifying which women will develop the disease. The BOADICEA model showed balanced performance, while others had significant limitations, emphasizing the need for continued improvement.
The American Cancer Society has endorsed two new types of stool tests and recommends limiting the use of blood tests for colorectal cancer screening. The guidelines aim to encourage people to get screened while improving detection rates.
The American Cancer Society has updated its guidelines for colorectal cancer screening, introducing blood-based and at-home stool testing options to increase accessibility. The new recommendations aim to close the screening gap and detect more cancers at an earlier stage, with a focus on underserved populations.
A Kaiser Permanente study found that HPV self-collection increased cervical cancer screening completion by 2.2% among over 95,000 members, with higher gains in diverse populations. The program also reduced clinician-performed pelvic exams and improved follow-up for high-risk HPV results.
Lanthanide nanoprobes have improved signal-to-noise ratio, enabling ultrasensitive detection of cancer biomarkers and visual identification of cancer cells. The nanoparticles maintain stable luminescence across a wide pH range and in simulated human body fluids, ensuring reliable performance.
Screening with a PSA blood test reduces prostate cancer deaths by approximately 2 for every 1,000 men screened. The review found that 500 men would need to be invited to screening to prevent one prostate cancer death.
A team of Rice University bioengineers has developed a new way to create highly realistic mock patient samples that could help accelerate the development of faster and more accessible cervical cancer screening tests. The approach combines multiple factors, including viral DNA levels and cell counts, to mimic real clinical specimens.
A study in Japan found that individuals with higher health literacy regarding gastric cancer and screening, those who perceived themselves to be at risk, and those who received encouragement from others exhibited stronger screening intentions. Concrete implementation intentions were also significantly linked to actual screening partici...
Researchers found a sustained reduction in colorectal cancer incidence and death associated with single flexible sigmoidoscopy screening, particularly in men. The study suggests that this screening method can provide long-lasting benefits beyond the usual 15-year screening age range.
Colleen Scott's patented research develops a shortwave infrared dye to visualize cancer cells, enabling safe and high-resolution deep tissue visualization. Her technology selectively targets cancer cells, allowing clinicians to identify tumor boundaries with greater precision.
The ERASur clinical trial is investigating whether total ablative therapy can improve overall survival in patients with newly diagnosed, limited metastatic colorectal cancer. The study has reached one-third patient accrual milestone, signaling strong momentum.
The ASPIRE trial aims to enroll 1,200 participants with advanced prostate cancer and assess the impact of chemotherapy on overall survival and disease progression. Genetic profiling is included to identify patients who benefit most from intensified treatment.
The review highlights how retrieval-augmented generation can improve the accuracy, transparency, and clinical reliability of AI tools in cancer care. RAG-enhanced systems produced more accurate results than standard AI models across multiple studies.
A new survey found that nearly half of women incorrectly believe annual mammograms should start at age 50. Experts recommend yearly mammograms starting at age 40 for average-risk women. This delay can lead to cancers being found at a later stage, when treatment can be more complex.
The new NCCN Guidelines for Patients: Prostate Cancer Screening provide a comprehensive guide to evidence-based recommendations for age-specific screening. The guidelines aim to balance the benefits of early detection with the risks of unnecessary procedures, emphasizing the importance of personalized care and monitoring.
Researchers found that a newer stool-based screening test, FIT-DNA, increased completion rates among participants from community health centers. However, follow-up colonoscopy tests remained low, highlighting the need for continued support and access to diagnostic services.
A new study found that prostate cancer overdiagnosis increases with age, with low rates in younger men and high rates in older men. The study suggests that targeted PSA testing or screening policies for men in their 50s and early 60s may be more effective.
A study by the Alliance Foundation Trials shows that combining immunotherapy and chemotherapy before surgery can help more patients with locally advanced non-small cell lung cancer undergo complete cancer resection, improving their long-term health. The treatment also led to high rates of lymph node clearance and successful surgical re...
Researchers have identified the Prrx1 gene as a key regulator of metastatic potential in breast cancer tumors. This discovery helps explain why highly invasive cells do not always give rise to metastases, and how cells combine invasiveness and proliferation to become the most dangerous from a clinical perspective.
Adults aged 75 or older without adenoma on prior colonoscopy have lower risk of subsequent colorectal cancer and CRC death. Despite this, those with prior adenoma may consider deprioritizing surveillance colonoscopy relative to other health concerns.
A national study found that unmet health-related social needs are associated with lower colorectal cancer screening rates, particularly among adults aged 50-64. Addressing these needs may support age-specific strategies to improve screening rates.
UCLA investigators present new research on targeted drug delivery for colorectal cancer, COVID-19's impact on breast cancer outcomes, and AI in cancer diagnosis. These studies offer insights into overcoming drug resistance, enhancing immune responses, and improving outcomes for patients with difficult-to-treat cancers.
A new article in JMIR Publications showcases precision oncology's success, where individualized multi-drug regimens improve treatment responses and survival rates for patients with advanced cancers. The study found that closely matching drug therapies to tumor mutations leads to better outcomes, while also offering a safer profile.
A new, cost-effective blood test detects liver, lung, ovarian, stomach cancers, and various non-cancer conditions by analyzing DNA fragments in the bloodstream. The test achieved high accuracy rates for multi-cancer detection and tissue-of-origin identification.
A recent study published in the Journal of General Internal Medicine found that women with diabetes are less likely to receive recommended preventive care services such as conception counseling and breast/cervical cancer screening. This oversight puts them at risk for preventable medical conditions like pregnancy complications.
A new study in China finds that onetime lowdose computed tomography (LDCT) screening can significantly reduce lung cancer mortality in a non–risk based population, including individuals with no smoking history. The findings support reconsideration of current eligibility criteria.
Researchers have reported early, reassuring results from the LORD trial on active surveillance for low-risk DCIS. The study found that patients with active surveillance did not experience worse early outcomes compared to those who underwent immediate surgery, and that many chose active surveillance over surgery.
A minimally invasive liquid biopsy test has been shown to diagnose Burkitt lymphoma rapidly and accurately in sub-Saharan Africa, where delays in traditional testing often prove fatal. The test achieved an overall accuracy of 98% and reduced the time needed to reach a diagnosis by 40 days on average.
Researchers compare prostate cancer screening to breast cancer screening, finding similarities in identifying significant cancers and reducing mortality. The study suggests that prostate cancer screening should be reconsidered, offering benefits over harms, and highlights the need for further analysis on costs.
A new imaging test, PSMA PET/CT scan, has been shown to safely reduce the number of biopsies needed for suspected prostate cancer, with no harm to patients. The PRIMARY2 trial found that the scan could identify low-risk patients who did not need a biopsy, while targeting suspicious areas for those who did.
Severe COVID-19 and influenza infections can prime the lungs for cancer development, according to new research. Vaccination, however, largely prevents these changes, suggesting a reduced risk of lung cancer.
Research presented at EAU26 confirms that prostate cancer screening leads to a reduction in mortality, but also detects cancers that would otherwise remain undetected. The study's findings suggest that using MRI in prostate cancer screening can reduce overdiagnosis and unnecessary biopsies.
The King Center for Lynch Syndrome will advance research, outreach, education, and patient care for Lynch syndrome, a hereditary condition affecting 1 in 279 individuals. The center will provide cutting-edge research, life-long comprehensive care, and increased awareness for patients and families affected by Lynch syndrome.
New research warns that popular AI systems for predicting cancer biology may rely on visual shortcuts, raising concerns about their reliability for real-world patient care. Despite achieving high accuracy, these models often fail when conditions change or confounding factors are controlled.
Renowned cancer clinician Dr. Daniela Matei will lead the Houston Methodist Dr. Mary and Ron Neal Cancer Center, bringing expertise in ovarian cancer treatment and therapeutics. She aims to bridge laboratory science to the clinic, advancing new concepts from bench to bedside.
A new fecal SDC2 methylation assay, combined with the Asia-Pacific Colorectal Screening Scoring (APCS), demonstrates superior performance in detecting advanced adenomas and stratifying risk. The test's high specificity makes it a valuable tool for prioritizing colonoscopy.