Articles tagged with Cancer Screening
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A new longitudinal study has provided unprecedented insights into human papillomavirus (HPV) infection dynamics. The study found that non-persistent infections exhibit a plateau in viral load before rapidly declining, while chronic infections show a strong correlation between immune cells and virus production. This research could infor...
BGI Genomics has launched a National Cervical Cancer Prevention and Control Program in Brunei, utilizing HPV DNA testing for large-scale screening. The initiative aims to increase accurate and reliable early detection methods, aligning with the WHO's global strategy of cervical cancer elimination by 2030.
The Tomosynthesis Mammographic Imaging Screening Trial (TMIST) has successfully enrolled over 108,000 women worldwide for a randomized controlled trial comparing 2D and 3D mammography. The study aims to determine whether 3D mammography is more effective in reducing advanced breast cancer risk.
A cross-sectional study found that American Indian/Alaska Native populations are significantly farther away from lung cancer screening centers than non-Hispanic White populations. The researchers recommend increasing access to lung cancer services through mobile units and imaging locations to address these disparities.
CITEC has announced its inaugural group of subawardees, who will develop innovative technologies for cancer detection and treatment in low-resource settings. The projects focus on improving HPV screening, developing deep learning algorithms for image analysis, and creating affordable microscopes for cancer screening.
A new UC San Francisco study found that most 11- and 12-year-olds use TikTok and other social media platforms against the rules, showing signs of addiction. The study also revealed a quarter of children reported elements of addiction while using social media, linked to depression, eating disorders, ADHD, and disruptive behaviors.
A recent review leverages AI in medical image interpretation to enhance cervical cancer detection accuracy and efficiency. The study explores the application of deep learning algorithms to automate cytology image segmentation and classification, improving early diagnosis and treatment outcomes.
A new study found that while lung cancer deaths decreased globally from 1990 to 2019, mortality linked to tobacco use and air pollution increased. Tobacco remains the leading cause of death, accounting for 66% of TBL cancer deaths in 2019, while particulate matter pollution is a growing concern.
Early detection of breast cancer can lead to less intensive treatments, saving the Canadian healthcare system $459.6M over women's lifetimes and 3,499 breast cancer deaths. Screening mammograms and diagnostics costs are easily offset by earlier stage treatment.
A case-control study found a link between advanced breast cancer stage and prevalent cardiovascular disease, with hormone receptor-positive and ERBB2-negative disease being more affected. Future studies are needed to confirm these findings and investigate interventions to improve patient outcomes.
A new study published in Nature Medicine shows that AI-based models can accurately identify ovarian cancer in ultrasound images, achieving an accuracy rate of 86.3%. The models also reduce the need for expert referrals and misdiagnosis rates by 63% and 18%, respectively.
A cohort study found a decrease in localized invasive breast cancer and regional invasive breast cancer since the 2009 guideline changes, but no decrease in advanced cancer stages. Further research is needed to understand these trends.
A recent study found that nearly two-fifths of women aged 40-49 did not receive biennial mammography screening, highlighting significant gaps in early detection. To optimize breast cancer detection, ensuring equitable adherence to U.S. Preventive Services Task Force recommendations is crucial.
A new study from Karolinska Institutet and Queen Mary University of London has developed a method to divide HPV-positive women into three risk groups, based on the variant of the HPV virus and the amount of virus present in the self-test. This method could enhance cervical cancer screening for high-risk women.
A new screening method combining laser analysis with AI identifies patients with breast cancer in its earliest stage, stage 1a. This non-invasive technique reveals subtle changes in the bloodstream that occur during the initial phases of the disease, outperforming existing early detection strategies.
Artificial intelligence is enhancing breast cancer risk prediction through mammographic analysis, uncovering key features that predict breast cancer risk. These AI-generated features may inform personalized screening strategies, such as more frequent or less frequent screenings for women at high or low risk of breast cancer.
A new study reveals that social risks like food insecurity and housing instability impede patients' ability to receive routine cancer screenings, even when they have access to healthcare. The research highlights the need for health providers to take a more holistic approach to patient care to address these challenges.
A new study finds that a blood test using phosphatidylethanol (PEth) can detect liver disease caused by excessive drinking, offering a more reliable alternative to self-reported measures. The test has shown strong correlation with Fibrosis 4, an indicator of liver risk, and could be included in routine blood tests.
The study found a significant increase in late-stage breast cancer diagnoses among U.S. women, with annual percentage increases of up to 2.9% between 2004 and 2021. The researchers attribute the trend to factors such as lack of national screening programs, inconsistent guidelines, and increasing obesity rates.
A new study suggests that a person's biological age can predict their risk of developing colon polyps and early colorectal cancer. Accelerated aging, which is higher than chronological age, may be linked to a greater risk of developing the disease, highlighting the importance of early screening.
A national lung cancer screening program is proposed to reduce deaths and improve survival rates for Australian patients. The Flinders University study found that screening individuals aged 50-70 every two years would be cost-effective and add significant years of healthy life.
A team of UNC-Chapel Hill researchers will develop an oncology health learning system using AI-ready data to generate real-time identification of new cancer cases and support personalized treatments. The project aims to improve cancer diagnosis, care equity, and quality by creating accessible tools for health providers.
A self-pay, AI-enhanced breast cancer screening program was offered to patients across 10 clinical practices, resulting in a 43% higher cancer detection rate among enrolled women. The AI-powered program attributed 21% of the increase in cancer detection, with higher-risk patients choosing to enroll more frequently.
The study estimated that prevention, screening, and treatment efforts in the US led to an average of 8 out of 10 cancer deaths being avoided for breast, cervical, colorectal, lung, and prostate cancers combined. The total number of averted cancer deaths was approximately 5.94 million between 1975 and 2020.
A recent NIH study found that prevention and screening interventions saved an estimated 4.75 million lives between 1975 and 2020, surpassing the impact of treatment advances for five major cancer types: breast, cervical, colorectal, lung, and prostate cancers.
A recent study develops a physicochemical approach to optical biosensing using 1DZnO nanostructures, enabling rapid CYFRA 21-1 testing within a 5-minute detection window. The developed biosensors have the potential to provide accurate and reliable results in complex matrices like saliva.
A cross-sectional study found that including race in disease risk models improves prediction accuracy, but the clinical net benefit is smaller than expected. The researchers provide a widely adaptable framework for deciding whether to include or exclude race from disease risk predictions.
A new study reveals that lung cancer screening CTs can detect coronary artery disease in 83% of cases, with high levels found in 30%. This finding highlights the potential benefits of lung cancer screening for identifying and managing cardiovascular risk factors.
A new study shows that mailing at-home fecal immunochemical testing kits and providing coordinated follow-up led to a tripling of screening completion rates compared to usual care. The intervention increased screening rates by 30% within six months and 34.6% by 12 months.
Achalasia is associated with an increased risk of esophageal squamous cell carcinoma, highlighting the need for close surveillance in high-risk patients. Chronic inflammation and food stasis can lead to malignant transformation, emphasizing the importance of timely intervention.
A recent study has uncovered a genetic variant in the PSA gene that is associated with aggressive prostate cancer. This finding could lead to the development of a novel point-of-care device that can identify high-risk patients with low blood PSA levels, enabling early detection and treatment.
A new University of Michigan study analyzed 2022 data from Michigan Medicare participants to assess the impact of virtual care on low-value care. The study found that high-telehealth-use clinics did not see a rise in unnecessary tests and scans, while some saw a faster drop in these procedures.
A comprehensive analysis of 52,000 men with prostate cancer treatment found substantial long-term risks of urinary and sexual complications. Men treated with radiotherapy faced a threefold risk of bladder cancer diagnosis, while those who underwent prostatectomy had a sixfold increased risk of complications.
Recent advancements in diagnostic techniques, including artificial intelligence integration, biomarker discoveries, and imaging technologies, have transformed the detection of pancreatic cancer. Key findings include improved sensitivity and accuracy of early-stage lesion identification using AI models, as well as the discovery of novel...
Research highlights the role of gut dysbiosis in pancreatic ductal adenocarcinoma (PDAC), with specific microbial profiles associated with PDAC. Fecal microbiota transplantation (FMT) is proposed as a potential adjunct therapy to improve patient outcomes through microbiome modulation and immune system recalibration.
The National Comprehensive Cancer Network has updated its guidelines for genetic/familial high-risk assessment, incorporating the latest scientific research and expert recommendations to enhance screening practices and treatment options. The expanded guidelines cover various cancer types and provide guidance on genetic testing, heredit...
A recent study demonstrates that stool DNA testing is highly sensitive and specific for detecting colorectal cancer among Thai individuals, with a sensitivity of 91.5% and specificity of 90.3%. The test targets methylation statuses of three genes and may provide a viable non-invasive alternative to colonoscopy.
A new study has found that Canadian women who did not identify as White have an earlier peak age of breast cancer diagnosis and higher proportions of cases diagnosed under age 50. They also experience an earlier peak age of death, with a 7-year gap in mortality rates compared to their White counterparts.
A low-dose CT scan can pick up on early-stage lung cancers, which can often be completely removed with surgery. However, less than a fifth of those eligible for the test are getting it, highlighting awareness and communication gaps.
A new initiative, CAL-PALS, aims to expand access to life-saving lung cancer screening for marginalized groups in Los Angeles County. The program will engage physicians and staff to create system-level changes increasing access to high-quality services.
A new survey by Ohio State University shows that most people believe pancreatic disease affects only the elderly and that there is nothing they can do to reduce their risk. However, obesity increases lifetime risk for pancreatic cancer by 20%.
Researchers found that using a multi-step strategy with less-invasive devices can identify patients with Barrett's oesophagus before an endoscopy. This approach is promising for cost-effective screening, which could lead to earlier diagnosis and treatment of oesophageal cancer.
A systematic review and meta-analysis found a significant association between Helicobacter pylori infection and the risk of cardia gastric cancer in Asian countries, with stronger associations observed in East Asia. The study suggests that H. pylori infection is a major risk factor for CGC in this region.
This study reveals a substantial increase in US elderly cutaneous malignant melanoma incidence rates, peaking at 1.53 per 1,000 males and 0.59 per 1,000 females aged 85+ from 2012 to 2016. Incidence rates escalated with age and birth cohort, with continuous increases observed.
A recent study by Stanford Medicine suggests that new blood-based colon cancer screening tests are effective for people who shun traditional methods. However, if too many switch to the new tests, colorectal cancer death rates may rise due to reduced detection of early cancers and precancerous polyps.
Researchers developed HPV16 peptide microspheres to induce specific cytotoxic T lymphocytes, leading to tumor regression in cervical cancer models. The approach combines peptide-based vaccinations with microsphere technology to enhance immune responses and eliminate tumor cells.
A new lung cancer screening initiative in Central Texas has successfully increased screenings among low-income and minority populations. The program's patient-centered approach, including bilingual support and no-cost screenings, resulted in an 83% completion rate of low-dose CT scans among eligible patients.
A new study from the University of Texas at Arlington suggests that analyzing RNA in urine can show changes in cell types, revealing early signs of cancer and other diseases. This method could help clinicians detect problems earlier when they are more easily treated without invasive procedures.
A Kaiser Permanente study found that close to 39% of adults aged 45-49 returned their FIT kit, compared to nearly 38% of adults aged 50. The study suggests that adults in this age group have a similar colorectal cancer risk as those aged 50.
College of Medicine – Tucson researchers are using a $3.3 million grant to test advanced breast computed tomography (CT) scans that create high-resolution 3-D images without physical compression, aiming to enhance early cancer detection and diagnosis for women with dense breasts. The technology has the potential to detect more breast c...
Researchers at Weill Cornell Medicine have developed a virtual screening approach to identify small molecule drug candidates targeting cancer checkpoints. The method successfully identified two compounds with potential therapeutic activity against TIM-3 and VISTA inhibitory checkpoints.
A new study by Concordia researchers found that one-third of adult childhood cancer survivors experience a severe fear of cancer recurrence, which can cause real distress. The study highlights the need for improved treatment and screening for this understudied population.
Cancer incidence recovered significantly in 2021 after substantial disruptions during the COVID-19 pandemic. However, further recovery is needed to address undiagnosed cases and meet healthcare demands.
Researchers identified three genetic regions strongly associated with increased prostate incidence in a diverse group of African men. The study, the largest of its kind in Africa, may lead to new treatment possibilities and refined screening methods.
Gastric cancer is the sixth most common cancer globally, with high incidence rates in Asia, Latin America, and parts of Europe. Screening programs focusing on H. pylori eradication and early detection have shown promise in reducing mortality rates. Emerging research explores serological markers for pre-screening tools and vaccination a...
A study by UC San Francisco found that more screen time is associated with severe symptoms of depression, anxiety, inattention, and aggression in 9-10 year olds. The effects were small but consistent, with activities like video chatting and playing video games strongly linked to depressive symptoms.
Adult childhood cancer survivors experience elevated fear of cancer recurrence, emphasizing the importance of routine screening and timely symptom intervention. The study's findings suggest that fear of cancer recurrence should be a significant concern in survivorship care.
A retrospective cohort study found that AI algorithms can identify women at high risk of developing breast cancer 4-6 years before detection. The results suggest using commercial AI algorithms as a pathway to personalized screening approaches, leading to earlier cancer diagnosis.
A new study published in JAMA Network Open found that racial and ethnic minorities are more likely to have claims for free preventive care denied by insurance plans, leading to unexpected bills or lack of access. Healthcare providers also charge disadvantaged groups a higher amount for preventive services.
A new study aims to increase follow-up care for patients who receive abnormal stool-based fecal immunochemical tests, focusing on improving coordination between primary and specialty clinics. The goal is to improve colorectal cancer screening processes in underserved populations, increasing survival and reducing mortality.