Researchers found that mice lacking STING developed signs of more damaging inflammation than normal aging brains. Microglia, a key immune cell, lost efficacy in clearing debris and supporting other brain cells.
A team of scientists at Pohang University of Science & Technology has developed a novel approach to enhance thermoelectric efficiency by controlling oxygen vacancies. By precisely controlling the number of oxygen vacancies in materials, they achieved a remarkable 91% improvement in thermoelectric performance.
Researchers at Tohoku University have developed an AI-built materials map that combines experimental data with computational predictions to identify promising materials for thermoelectric waste-heat recovery. The map enables faster development timelines and reduces trial-and-error, accelerating innovation in energy-related technologies.
A comprehensive study reveals critical vulnerabilities in smart railways, from data breaches to operational sabotage. Key findings propose comprehensive mitigation strategies, emphasizing human factors and staff training in building cyber-resilient systems.
CURE GABA-A and Grann Pharmaceuticals partner to advance mRNA lipid nanoparticle therapies for Rett Syndrome and other rare neurodevelopmental disorders caused by GABAAR variants. The partnership aims to accelerate clinical trials and deliver transformative therapies to families affected by these conditions.
A novel manganese(I) complex has been developed, combining a record-breaking excited-state lifetime with simple synthesis, offering a powerful and sustainable alternative to noble metal complexes. The complex exhibits strong absorption and overcomes the challenges of tedious synthesis and short lifetimes of excited states.
A new study finds that PAD2-mediated histone citrullination promotes tumor cell proliferation in pancreatic ductal adenocarcinoma. Knocking down the PAD2 gene reduces cell growth and increases survival rates. The researchers identify PAD inhibitors as potential therapeutic targets for treating PDAC.
Research finds lemurs evolved in multiple successive radiations, with hybridization contributing to new species emergence. Over 100 lemur species exist, but many are endangered due to habitat destruction and climate change.
Researchers developed a new origami-inspired folding strategy for reversible actuation of hydrogel pores, integrating facet-driven folding into polygonal pores to enable programmable and predictable actuation. This strategy retained 90% of its original shape after repeated swelling-shrinking cycles, demonstrating excellent reliability.
Climate change will lead to increased turbulence in flights, causing clearer-air turbulence that can't be seen on radar. Wind shear will rise by 16-27%, making it harder for pilots to avoid sudden jolts, and air stability will decrease by 10-20%.
Researchers developed a hybrid pair trading strategy for cryptocurrency markets, achieving profitable results in high-frequency trading. The approach outperformed traditional methods by combining statistical techniques and adjusting entry/exit thresholds to maximize profits.
Researchers Marie Teich and Wilmer Leal develop a formal framework to analyze metaphors, confirming they are enduring linguistic and cognitive structures. The study reveals two significant metaphorical processes: mappings from concrete to abstract topics and the emergence of new mappings between domains.
Researchers develop a method to transform spin-glass-like quasicrystals into ferromagnetic materials with tunable magnetic properties and strong magnetocaloric response. The technique enables expanded electron-to-atom ratios, unlocking new possibilities for designing high-performance magnetic refrigeration materials.
A nationwide study analyzed data from over 2019 trauma patients treated at Level III or non-trauma centers and found that older age, public insurance, and lower designations are strong predictors of non-transfer to necessary higher-level care. The study highlights the need for strengthened trauma systems to ensure all patients receive ...
A team of researchers has developed a new method to produce sturdy and reusable bioplastics from domestic raw materials, reducing reliance on petroleum-based chemicals. The bioplastics, known as polyhydroxyalkanoates (PHAs), have similar levels of toughness and malleability to traditional plastics, but are infinitely recyclable.
A new study published in Science Advances predicts a significant increase in supercell thunderstorms across Europe, with the Alpine region and northern side of the Alps expected to see up to 50% more storms. The simulations show that temperature increases of 3 degrees Celsius will concentrate these storms in the region.
A new species of hypercarnivorous crocodyliform, Kostensuchus atrox, has been discovered in prehistoric Patagonia with a length of 11.5ft and weight of 250kg. This predator was likely one of the top predators in its ecosystem.
The discovery of Spicomellus afer reveals an armoured dinosaur with metre-long spikes on its neck and tail weapon, showcasing the diversity of ankylosaurs' armour. This find pushes back the evolution of ankylosaur tail weapons by over 30 million years.
Scientists at CUNY ASRC develop novel synthetic carbohydrate receptors that block infection from seven different viruses across five unrelated families, including Ebola and SARS-CoV-2. The breakthrough offers a promising path toward the development of broad-spectrum antivirals.
Researchers at Baylor College of Medicine identified a biomarker that indicates ER+ breast cancers are more likely to respond to treatment with CDK4/6 inhibitors. This marker, low levels of tumor suppressor protein NF1, could help identify patients who may benefit from these agents.
This study identifies ulcerative colitis as the most common subtype of IBD in Nigeria, with rectal bleeding being the predominant clinical feature. The findings highlight significant management challenges due to high medication costs and limited availability, affecting nearly half of patients.
The Molecular Analysis for Precision Oncology Congress 2025 (MAP) brings together leading experts to explore the latest cancer research advances. Key topics include AI-integrated diagnostics and therapy, as well as immunotherapy and emerging developments in aging and cellular senescence.
A new species of bacteria of the genus Bartonella has been found in the Amazon National Park, Brazil. The DNA is similar to that of two other Andean species, B. bacilliformis and B. ancashensis, which cause Carrión's disease. No evidence suggests this new species can cause disease, but further studies are needed.
Research on killifish reveals that maternal exposure to toxic substances like crude oil and flame retardants can have lasting impacts on offspring and subsequent generations. Exposure to these chemicals during critical developmental windows can alter gene function, behavior, and health outcomes in humans and wildlife.
A research study by Radboud University Medical Center found that an innovative backpack called Gyropack improves balance and reduces the need for walkers in patients with ataxia. The backpack uses gyroscopic technology to generate resistance to rotations, resulting in improved posture and balance.
The University of Cincinnati has established the Center for Explainable, Ethical and Trustworthy AI (CEET) with a $498,430 federal grant. The center will explore AI explainability, ethics, and trustworthiness through research and public engagement initiatives.
The American Meteorological Society honors individuals and organizations with the 2026 Awards and Honors, recognizing their exceptional work in weather, water, and climate research. This year's recipients include scientists awarded prestigious medals for groundbreaking research in atmospheric dynamics, hydrology, and remote sensing.
Researchers found cosmic dust with crystalline structures and PAHs in the Butterfly Nebula, revealing how rocky planets form. The discovery provides a clearer picture of planetary nebula formation.
Insomnia patients taking cannabis-based medical products reported significant improvements in sleep quality, anxiety, and pain over 18 months. The study found sustained benefits with minimal side effects, suggesting potential for medical cannabis as an option for conventional treatments.
Researchers analyzed neuroimaging data from over 650 individuals aged 8 to 21, discovering a key organizational shift in the dorsal prefrontal cortex. The study found that this refinement of brain architecture is driven by specific changes in the medial part of the prefrontal cortex.
Artificial neural networks offer superior predictive accuracy in predicting biodiesel properties and enable rapid assessment of diverse feedstock options. Hybrid models combining generative and discriminative approaches achieve significant yield improvements and optimize biodiesel production from waste cooking oil.
Researchers have created glow-in-the-dark succulents using light-emitting compounds that absorb and release light slowly. The plants can shine in various colors and stay lit for up to two hours after exposure to sunlight or indoor LED light.
Hebrew SeniorLife's 108 Centre Street affordable senior housing building has achieved Phius Certification for its high-performance, energy-efficient design. The seven-story building provides 54 affordable apartments for seniors and advances sustainable, healthy housing in Greater Boston.
Researchers found that orangutans outshine humans in avoiding obesity by adjusting their nutrient intake, behavior, and energy use. The study provides insights into the evolutionary adaptations of great apes, which can inform better nutritional practices for humans.
Scientists at Gladstone Institutes discovered that overactivated dopamine neurons degenerate and die, leading to Parkinson's disease symptoms. Chronic activation of these cells can cause cell death, potentially triggered by genetic, environmental toxins, and compensating for lost neurons.
ConcreteSC technology achieves significant speed boosts and improved efficiency in next-generation wireless networks. The innovation integrates user tasks into communication processes, reducing computational complexity and increasing semantic meaning.
New research reveals that older age and low aerobic fitness levels are strong and independent risk factors for heartbeat irregularities, or arrhythmias, in healthy adults. Regular exercise can help reduce the risk of frequent and complex atrial arrhythmias.
A study in Nature Communications reveals that older species typically have larger geographical ranges, except for island dwellers. On the mainland, this relationship holds true, while on islands, younger species can attain larger ranges due to unique environmental dynamics.
This review synthesizes evidence from clinical trials on the efficacy of transcutaneous vagal nerve stimulation (tVNS) in managing abdominal pain, improving gastrointestinal symptoms, and enhancing motility in disorders such as functional dyspepsia, gastroparesis, irritable bowel syndrome, and inflammatory bowel disease. tVNS demonstra...
Researchers identified two major steps in the evolution of human bipedality, involving a shift in the growth plate and changes in bone formation. These genetic shifts, driven by genes such as SOX9 and PTH1R, fundamentally altered the pelvis geometry, enabling humans to walk upright.
The study found a significant association between higher serum 25-hydroxyvitamin D levels and increased risks of nonmelanoma skin cancer, melanoma, and other skin cancers. Risks were highest in males, older adults, and individuals with obesity.
Preliminary findings suggest that neuroimaging and mobile sensing can identify neural and behavioral markers of bipolar disorder and mood recurrence. Dr. Danella Hafeman's research uses fMRI and mobile sensing to detect early indicators of depressive and manic symptoms.
Researchers found that local climate heating caused by tropical deforestation is associated with 28,000 heat-related deaths each year, affecting over 48 million people in Indonesia, DRC, and Brazil. Deforestation eliminates trees that regulate the climate, leading to increased temperatures and greenhouse gas concentrations.
Researchers achieved a significant reduction in aerodynamic drag by optimizing multiple train components, including nose shape and pantograph design. The study found that simultaneously enhancing these components can deliver notable improvements and even certain bogie fairing configurations might offer advantages over traditional designs.
Researchers developed a multi-analyte test that accurately identifies brain cancers using small samples of cerebrospinal fluid, offering a promising new tool for guiding clinical decision-making. The test combines multiple biological markers and demonstrates high sensitivity and specificity in detecting central nervous system cancers.
A new study suggests that the 'unhappiness hump' has disappeared globally, with declining mental health among younger people being a key factor. This shift is in contrast to past trends, where mental ill-being typically peaked in midlife and declined with age.
Researchers identify unhealthy lifestyle habits, hormonal imbalances, and chronic inflammation as key contributors to skin aging and disease. Maintaining a balanced diet rich in fiber, phytochemicals, and specific probiotics may promote overall well-being and enhance skin health.
A new study found that treatment of heart failure patients with GLP-1 receptor agonists reduces hospitalizations, calorie intake, and greenhouse gas emissions. The study estimates a potential annual CO2-equivalent saving of over 2 billion kilograms, equivalent to 20,000 Boeing 747 flights.
The global market for AI in pharmaceuticals is projected to reach $13.4 billion by 2035, driven by Insilico Medicine's innovative use of generative AI. The company will share its achievements at a satellite forum during BIOHK2025, showcasing significant efficiency boosts compared to traditional methods.
Researchers from Shinshu University have developed a unique fiber-based pressure sensor that can detect small changes in pressure, enabling fine-tuned tactile sensing. The fibers exhibit a multi-wall structure that increases resistance when compressed, making them ideal for applications such as soft robotics and wearable devices.
A new study finds that only 91 four-year colleges in the US effectively serve low-income students, leaving many states without institutions meeting the criteria. States like California and Florida have strong access to these 'Equity Engines,' while others struggle to support low-income student success.
Researchers at USF and FAU have uncovered direct genomic evidence of the bacterium behind the Plague of Justinian, providing long-sought definitive proof that Yersinia pestis was present within the Byzantine Empire. The discovery offers new insight into one of the most consequential episodes in human history.
A team from UNIGE and INGV created a high-resolution 3D image of Vulcano's internal structure using seismic ambient noise tomography and AI. This breakthrough understanding of volcanic structures may lead to more accurate predictions and evacuation plans.
A new study led by UCLA researchers found that many patients with advanced cancer feel their treatment does not align with their personal care goals. The study reveals a significant disparity in care preferences between patients with advanced cancer and those with other serious illnesses, suggesting a need for improved communication an...
A new study of young adults found that better sleep quality is strongly linked to improved mental wellbeing, with fruit and vegetable consumption and physical activity also showing benefits. The study suggests that boosting fruit and vegetable intake may help mitigate the effects of poor sleep on wellbeing.
A new study introduces an optical imaging technique that uses autofluorescence to detect colorectal cancer in real time, offering a promising tool for improving cancer detection during endoscopic procedures. The technique achieved high accuracy rates and the potential to guide doctors during colonoscopy or surgery.
A new UCLA-led study finds that government housing assistance reduces the risk of medical bill stress by nearly seven percentage points among US renters with cancer, leading to improved quality of life and reduced poor physical and mental health outcomes.
Researchers have developed 'molecular scissors' that can precisely and permanently disable the hepatitis B virus's hidden genetic material. The treatment has shown promising results in laboratory tests and HBV-infected mice, with a 99% reduction in circulating viral DNA. This innovation represents a significant step towards a functiona...
A new study found that automatic chest compression devices can effectively perform CPR on a floating manikin, reaching depths of up to 53mm. This finding contradicts current NASA emergency protocols and suggests space agencies may need to reconsider their guidelines for treating cardiac arrest in space.
A new intervention, HABIT, shows promising results in improving the quality of life for adolescents with sickle cell disease by increasing hydroxyurea uptake and reducing pain and hospitalizations. However, effects were not sustained at the end of the trial, highlighting the need for further research to develop more effective methods.
Research findings suggest intrusive distracting thoughts associated with anxiety and lower well-being. The study also revealed that these thoughts occur more often when individuals are alone compared to being in company.
New research reveals that many protoplanetary discs are subtly warped, challenging the textbook picture of flat discs. These small warps can naturally explain large-scale patterns observed in gas motion and may be responsible for creating spiral patterns and temperature variations within cosmic nurseries.
A cross-sectional study found that the bivalent HPV vaccine induces sustained immunity in Bangladeshi adolescent girls, with significant associations between HPV16/18 seropositivity and age, grade level, and household income. The overall seroprevalence was high, with 72.8% for HPV16 and 82.4% for HPV18.
A recent study uncovered the mechanism of action of PspA, a protective protein that actively reshapes cell membranes without requiring any external energy. The findings shed light on a fundamental biological repair process and may have potential biotechnological applications.
A study by Mass General Brigham researchers found that the law significantly reduced out-of-pocket costs, but high burden medical spending remained unchanged. The findings suggest that additional policy efforts are needed to reduce healthcare-related financial burden, particularly among socioeconomically disadvantaged populations.
Researchers discovered a new enzyme, PNGaseL, with broader specificity than existing alternatives. It can target glycans from mammalian, insect, and plant-derived proteins, expanding its utility in glycobiological settings. The study was published in The Royal Society Open Science journal.
Robotics experts disagree with claims that humanoid robots will surpass human capabilities in surgery, factory work, and serving as personal butlers. The main limitation is dexterity, making tasks like picking up objects difficult for current robot technology.
A new WSU study found that local communities were not overwhelmed by COVID-19 cases linked to returning students. The study suggests mitigation efforts like testing and social distancing limited the spread of the virus.
Researchers at UCL successfully chemically linked amino acids to RNA under conditions that could have occurred on early Earth, a significant step towards understanding the origin of protein synthesis. The study demonstrates how RNA might have first come to control protein synthesis.
A new study by the University of Surrey found that schools struggle to address sexual harm due to narrow definitions and institutional constraints. The research proposes a 'both/and' approach combining swift responses with long-term cultural change to build environments where harmful behaviors are less likely to occur.
Researchers at Children's Hospital of Philadelphia found that certain lipids in obesity-causing foods cause asthma-like lung inflammation. The study suggests that modifying dietary choices and repurposing existing drugs could help treat this type of asthma, which is more likely to send patients to the hospital.
The Global Virus Network has selected five early-career virologists for its Rising Star Mentorship Program, a two-year initiative that provides personalized mentorship and financial support. The awardees will focus on addressing the global shortage of virologists, particularly in low- and middle-income countries.
Researchers found that differences in tectonic plate thickness explain the extensive volcanism. Thinner lithosphere funneled hot plume material, causing uplift and volcanic activity. The study sheds light on global significance of the Iceland Plume.
A new study from the University of Illinois examines whether teacher training programs and reading camps can improve literacy levels in rural Mozambique. The research found that light-touch training had little effect on overall literacy scores, but showed a small positive impact for lower-scoring children.
Researchers at Wayne State University are developing an ultra-rapid insulin designed to mimic the human pancreas, aiming to improve glycemic control and reduce disease management burden. The project has the potential to create fully automated systems, enabling patients to manage their condition with fewer interruptions.
A new study published in Clinical Gastroenterology and Hepatology shows that AI analysis can accurately identify mucosal ulceration as well as human reviewers, providing a more objective and reproducible assessment of Crohn's disease. The findings have potential implications for education, drug development, and automated care.
Research reveals a major shift in South Pacific climate conditions around 1,000 years ago, prompting people to settle further east and move away from drier conditions. The climate shift saw western areas become progressively drier while eastern areas became wetter and more attractive for colonization.
Researchers at POSTECH and Korea Brain Research Institute unveil NeuO's mechanism of selective neuron staining through PAK6 kinase phosphorylation. This breakthrough opens path for precise tracking and study of living neurons in brain.
A recent study has found that 43.9% of Black women with disabilities are pursuing self-employment as a viable career option. This group is more likely to have a graduate degree and earn higher incomes compared to their non-disabled counterparts.
Genomic analysis reveals amblyopsid species lost vision between 2.25 and 11.3 million years ago, allowing researchers to estimate minimum age of caves. The study provides a unique method for dating underground ecosystems and may hold implications for human eye diseases.
A new UN report reveals that global agricultural trade affects water access, alleviating water scarcity for high-income populations while intensifying shortages for low-income communities. The report calls for measures to address outstanding water inequity issues resulting from international food trades.
Researchers found that AUF1 helps prevent aging by breaking down enzymes involved in glucose metabolism. The study's findings improve our understanding of how metabolism affects the aging process.
Albino cane toads created using CRISPR technology reveal that albinism affects survival and hunting abilities, with poor eyesight being the core problem. In controlled environments, albino tadpoles were less likely to survive and developed faster when competing with pigmented siblings for food and space.
Treatment with exagamglogene autotemcel (exa-cel) leads to clinically meaningful improvements in overall quality of life for patients with severe sickle cell disease and transfusion-dependent beta thalassemia. Patients experience substantial improvements in physical, social, functional, and emotional well-being, with sustained benefits...
Researchers discovered mutations in the SPNS1 gene disrupt cellular recycling, leading to progressive liver and muscle damage. The study offers fresh hope for treatment and sheds light on the importance of phospholipid recycling in maintaining energy balance.
Researchers from Seoul National University of Science & Technology developed a smart adhesive system based on starfish for temporary and switchable underwater adhesion. The system exhibits high adhesion hysteresis, automatic release based on outside stimuli, and quick detachment by pneumatic actuation.
A study by JGU researchers finds that indirect interactions between species can profoundly influence each other's evolution. The research demonstrated that land-based aphids influenced the evolution of aquatic Daphnia crustaceans, highlighting a crucial evolutionary mechanism.
A 12-week online program has been shown to be effective in treating bulimia nervosa, with a significant reduction in binge eating and compensatory behaviors. The study found that guided internet-based CBT can help people who struggle to access specialist care.
Researchers developed Sc3+-modified Mg-Al-Mn-Fe-O spinel ceramics that exhibit synergistic breakthroughs in microwave dielectric and thermosensitive properties. The ceramics display NTC thermistor behavior across an extended temperature range, with exceptional microwave dielectric performance.
Researchers used CRISPR gene editing to bring back a human lost gene that breaks down uric acid, a waste product causing gout and related health issues. The study showed promising results in lowering uric acid levels and preventing fat buildup in liver cells.
Researchers have discovered that gut bacteria can recognize diverse chemical signals, including those from nutrients, DNA, and other metabolites. This allows them to detect and respond to nutritional values, suggesting that finding sources of nutrients is a primary function of motility in these bacteria.
Researchers have visualized and manipulated electron emission from chiral molecules in real-time using attosecond pulses. This discovery opens a new avenue for studying chirality and its role in biology, chemistry, and the pharmaceutical industry.
A comprehensive study published in the Journal of Hepatology shows that healthy eating and increased physical activity significantly lower the risk of liver-related death, even among heavy and binge drinkers. The research analyzed data from over 60,000 US adults and found that adherence to high levels of physical activity and/or diet q...
A case series of 19 patients has successfully undergone partial heart transplant, enabling valve growth and representing a novel approach to congenital heart disease treatment. Careful follow-up and monitoring are crucial for the continued expansion of this procedure.
Researchers developed a roadmap for scalable, high-density storage that converts CO2 into grid-level energy. The review outlines ten years of progress and future directions, including dual-electrolyte architectures, AI-guided additive screening, and temperature-resilient designs.
A new AI-powered solution enables robots to navigate without a map by training them to evaluate visual richness and avoid collisions. The approach combines deep reinforcement learning with real-time feedback from RGB-D camera input and ORB-SLAM2, achieving improved navigation success rates in simulated tests.
Scientists have developed ingestible devices that deliver targeted light stimulation directly to the gut, allowing researchers to precisely illuminate specific nerve cells. This technology could reveal new targets for treating conditions like gastroparesis and metabolic diseases.
Professor Matt Rosseinsky, a leading researcher at the University of Liverpool, has been awarded the Royal Medal for his groundbreaking work in materials chemistry. His innovative approach uses artificial intelligence to design and discover new materials with unique properties.
Researchers mapped the surface envelope glycoprotein of human endogenous retroviruses, opening doors to new diagnostic and therapeutic opportunities. The study revealed specific antibodies that target the viral proteins, potentially leading to new cancer immunotherapies and treatments for autoimmune diseases.
A new study found that 14% of bariatric surgery patients use GLP-1 weight loss drugs, with higher rates among those who underwent sleeve gastrectomy and experienced lower post-operative weight loss. The rate of GLP-1 use increased as more powerful drugs became available.
A new report from RMIT University and the University of Canberra proposes that local news organisations must adapt to their audiences' shifting news habits. The report recommends embracing community-driven content, including hyperlocal news, human-interest stories, and practical information.
Researchers are using nanodiamonds and VEGF to design treatments for Congenital Diaphragmatic Hernia (CDH), a devastating disease affecting 1 in 3,000 newborns. The treatment aims to stimulate lung growth before birth and improve survival rates.
Researchers discovered that atherosclerotic plaques contain gelatinous biofilms formed by bacteria, which can trigger inflammation and rupture of the plaque leading to myocardial infarction. The study also validated an antibody targeting these bacteria, suggesting new diagnostic and therapeutic strategies for myocardial infarction.
Researchers at Stockholm University have mapped the entire 14-part protein complex of botulinum toxin, revealing its structure and mechanism. The breakthrough opens up possibilities for neutralizing the toxin or harnessing its mechanisms for therapeutic use.
A recent University of Konstanz study found that political parties in twelve democratic OECD countries neglect to address economic inequality in their manifestos. The issue plays a relatively small role in election platforms, with left-wing parties and governments being the exception, as they react only when income levels increase.
Researchers discovered that GLP-2 analogs reshape the intestinal environment by expanding villi and crypts, increasing regulatory T cells, and improving nutrient absorption. This breakthrough offers new hope for patients with short bowel syndrome and potentially benefits immunocompromised individuals.
Researchers found that people with emotional insecurities react strongly to their partner's phone use, reporting lower self-esteem and greater resentment. Simple steps like creating phone-free zones can help protect relationships.
Researchers at UC San Diego and NIDA developed a new biochemical approach to combat addiction by custom engineering ion channels to be activated by cocaine, breaking the positive feedback loop. This approach could lead to gene therapies for cocaine addiction that preserve enjoyment of regular activities.
High ventilation breathwork with music is linked to altered states of consciousness, reduced negative emotions, and increased blood flow to the right amygdala and anterior hippocampus. The study found that breathwork practices can induce profound psychedelic states similar to those evoked by psychedelic substances.
Researchers have developed triboelectric nanogenerators that can harness wave energy with high efficiency and stability. These devices use advanced designs such as multilayer stacks and magnetic-levitation frames to push volumetric power density beyond 600 W m–3, creating full-spectrum harvesters that deliver 117% power-conversion effi...
Researchers found signs of osteomyelitis in sauropod fossils from the Cretaceous period, suggesting a fatal bone disease that killed animals quickly. The study identified three previously unknown manifestations of osteomyelitis and provides insights into the environment that favored pathogens.
A retrospective cohort study found that approximately 1 in 10 US adults undergoing bariatric surgery initiated glucagon-like peptide-1 receptor agonists. The use of these medications was more common among women and individuals with larger body mass index regain after surgery.
Researchers at Lehigh University and the Cleveland Clinic are developing a nonsurgical therapy for pelvic organ prolapse using drug-delivering nanoparticles. The treatment aims to delay or reverse matrix degradation, reducing the severity of POP in patients with earlier stages of the disorder.
A UCLA study reveals how a region of the medial prefrontal cortex integrates information across the brain to coordinate physiological and behavioral responses. The findings could help develop targeted therapies for stress-related and social dysfunction disorders.
Researchers developed a reliable and affordable purification technique for chromatography using calcium chloride, applying to organic compounds like amines and peptides. The technique has shown promising results in purifying APIs with high accuracy.
A cross-sectional study found associations between HbA1c levels and modern diabetes technologies and insulin accessibility. Efforts to ensure universal accessibility are crucial to reduce global inequities in glycemic outcomes for children with type 1 diabetes.
Researchers developed a groundbreaking solution to tackle both energy efficiency and ride comfort challenges in electric vehicles. The innovative Teamwork Optimization Algorithm (TOA) dynamically adjusts the motor's magnetic flux for optimal performance, resulting in reduced energy consumption by up to 15%, smoother acceleration with 4...
Researchers at the University of Vaasa developed smart packaging that can detect subtle color changes in printed packages, enabling cost-effective solutions for industries like food and beverage, healthcare, and logistics. This technology provides a human-eye accurate and environmentally friendly alternative to electronic sensors, pavi...
Researchers discovered that disordered regions of the ZFTA-RELA fusion protein cause the formation of droplets within cells called condensates, which are essential for ependymoma development. The study provides a new therapeutic frontier by targeting the interacting partners within these condensates.
A new investigational drug, ION224, shows promise in treating metabolic dysfunction-associated steatohepatitis (MASH), a serious form of fatty liver disease. By targeting the DGAT2 enzyme, the drug helps reduce fat buildup and inflammation, two major drivers of liver damage.
A new study found that Native Hawaiian or Pacific Islander people had the highest rate of stroke among all racial and ethnic groups, with a rate of 591 cases per 100,000 people. The study also showed significant disparities in stroke risk among different racial and ethnic groups.
Dr. Valentin Fuster, a renowned cardiovascular expert, has been awarded the inaugural World Heart Federation oration lecture for his groundbreaking work in promoting global cardiovascular health. He will discuss early detection and education as key strategies for preventing heart disease, focusing on low- and middle-income countries.
Scientists have developed a method to make a juvenile mouse's scalp transparent, allowing them to image the developing connections in a living mouse's brain. This breakthrough enables researchers to study neurodevelopmental disorders and potentially lead to new interventions.
A new study by Cornell University researchers found that certain pond plant communities can increase greenhouse gas production, transport, and emissions. The composition of aquatic plant communities in shallow freshwater bodies can have significant effects on greenhouse gas concentrations and fluxes.
A new study reveals that drought and ozone pollution significantly reduce soybean yield, regardless of drought stress levels. Researchers found that elevated ozone concentrations disrupt photosynthesis and hormone signaling in plants, leading to reduced yield and seed development.
Researchers have identified specialized immune cells in the intestine that produce chemical messengers triggering anaphylaxis. Targeting these chemicals, like zileuton, may offer a new approach to preventing food-triggered anaphylaxis.
A study found that hormone therapy type impacts memory performance in postmenopausal women, with transdermal estradiol patches enhancing episodic memory and pill form improving prospective memory. The type of hormone therapy taken during and after menopause may influence cognitive performance differently across various types of memory.
A high protein diet, rich in tryptophan, increases the risk of cancer-associated venous thrombosis. The study found that inhibiting tryptophan metabolism and blocking its metabolite Kynurenine can mitigate this risk.
Late-breaking clinical trials and science at TCT 2025 will present pivotal data on novel therapies, devices, and techniques aimed at preventing and treating cardiovascular conditions. The symposium delivers high-impact findings that shape clinical practice and enhance outcomes for patients with heart and vascular disease.
Researchers used ancient DNA and computer simulations to determine that migration of farming groups was the dominant factor in the expansion of farming, while cultural adoption by hunter-gatherers played a minimal role. The study found that the adoption of new ideas and practices did not significantly accelerate the spread of agriculture.
Scientists have developed wheat plants that produce their own fertilizer through a bacterial work-around, opening the path toward less air and water pollution worldwide. This breakthrough could be a boon for food security in developing countries, especially Africa where fertilizers are often unaffordable.
A new study by University of Wisconsin-Madison researchers found that life expectancy gains made in high-income countries have slowed significantly since the first half of the 20th century. As a result, none of the generations born after 1939 will reach 100 years of age on average.
Researchers from SUTD developed a generative urban model that optimizes designs for both pedestrians and vehicles, challenging the assumption that walkable neighbourhoods must come at the expense of road access. The study found examples of well-balanced layouts that enhanced pedestrian reach without drastically compromising road access.
Kanishka Thiran Jayasundera has been appointed professor and chair of the Department of Ophthalmology and Vision Science at UC Davis Health. He is recognized for his research on retinal diseases and integrating mental health support with eye care.
Researchers successfully created functional ureter tissue from pluripotent stem cells, bringing them closer to developing transplantable kidneys that can produce and expel urine. The achievement is a significant step toward next-generation regenerative therapies.
A major international review found that targeted approaches such as regular supervised exercise, vitamin D supplements, and improved nutrition can significantly reduce falls in aged care homes. The study also highlights the importance of individualized programs delivered with strong staff engagement.
A study published in The BMJ found that women diagnosed with early breast cancer have a low long-term risk of developing a second primary cancer, with risks varying by age and treatment. Researchers used data from the National Cancer Registration and Analysis Service to estimate these risks.
A new study identifies a critical gene that regulates immune responses in female T cells but not in males. This discovery may lead to more effective treatments tailored to biological sex for diseases such as severe asthma and infections affecting millions of people worldwide.
Researchers found that sharks' teeth become structurally weaker and more prone to break in acidic oceans. The study suggests that even small damage can have significant effects on these apex predators.
Researchers developed a wax-assisted exfoliation method to fabricate high-quality MnBi2Te4 devices with dual-surface AlOx encapsulation. This approach significantly improved the robustness of topological phases in MnBi2Te4, leading to the observation of enhanced axion insulator states and quantum anomalous Hall effects.
Birdwatching tourism has seen significant growth globally, with countries in the tropics experiencing increased visitation and economic development. However, not all countries have benefited equally, with research from UC Santa Cruz identifying challenges and success stories that may inform future conservation efforts.
Research from Harbin University of Science and Technology and Edith Cowan University found that China's environmental regulations could enhance productivity in the new energy sector. The study investigated how environmental policies affect firm-level productivity, particularly in regions with varying levels of technological innovation.
SHEA expresses disappointment over the sudden departure of the CDC Director, emphasizing the agency's need for stability and authority to protect public health. Qualified, steady leadership is essential to guide the CDC through urgent challenges and prepare for future pandemics.
The study reveals data visualization primarily facilitates decision-making at the organizational and community levels, particularly for semi-structured problems. Recent trends indicate increasing support for broader types of decision-making, including individual-level and unstructured problems.