A study by researchers at Georgia State University found that chronic intestinal inflammation can drive cardiac dysfunction through changes in gut microbiota and immune cells. The study identified a bacterial component called lipopolysaccharide as an important link between the gut and heart.
Georgia State University graduate students Ahanab Hafiz Anab and Haobo Cui have received the 2026 Graduate Award from the Southeastern Universities Research Association for their exceptional academic and research talent in STEM fields. The award recognizes their potential to advance science and technology.
Researchers at Georgia State University discovered two metabolite-inspired compounds, MLY2 and MLY8, with enhanced anti-inflammatory activity in experimental ulcerative colitis. These compounds showed promise for treating the chronic inflammatory disease, offering an underexplored drug discovery opportunity.
Astronomers using the Georgia State University Telescope array have found that nearby stars darken toward their edges more strongly at near-infrared wavelengths than predicted by several widely used models of stellar atmospheres. This effect, known as limb darkening, makes a star appear fainter at its edge than at its center.
New studies from Georgia State University researchers provide critical insights into Powassan virus disease progression, immune responses, and long-term neurological damage. The research sheds light on the molecular mechanisms driving neurological damage and identifies key immune defense mechanisms.
The project will complete fiber-optic connections between telescopes, enabling longer baselines and higher angular resolution. This will allow researchers to study the environments immediately surrounding massive stars with unprecedented detail.
A new class of protein-based MRI contrast agent detects invasive lung cancer and metastatic disease at earlier stages than conventional imaging approaches. The technology targets collagen type I, a structural protein found at elevated levels in aggressive lung tumors and metastatic lesions.
A new study reveals that schizophrenia affects not only how strongly brain networks engage relative to one another, but also how effectively they return to balance after disruption. People with schizophrenia experience more frequent imbalances in signal strength, recover more slowly, and have altered recovery processes related to sympt...
A new oral antiviral drug candidate, GHP-88310, efficiently blocks both forms of viral spread and shortens the time period infected animals can transmit the virus. The study demonstrates the drug's suitability to augment traditional ring vaccination against measles.
A five-year study will focus on developing and evaluating compounds to treat best vitelliform macular dystrophy, a rare inherited retinal disease affecting the retina. The research aims to improve patients' lives by preserving sight.
The study demonstrates how environmentally responsible strategies can be integrated into chemistry classes while maintaining academic rigor. Students at Georgia State University conducted a redesigned experiment as part of their coursework, experiencing green chemistry concepts directly in the lab.
A new oral antiviral drug candidate, GHP-88310, has been identified for the treatment of orthoparamyxovirus diseases such as measles and Croup syndrome. The compound is effective against a broad spectrum of viruses when taken once daily by mouth and has excellent tolerability.
A new $1.75 million grant from the Merck Foundation aims to address barriers to good heart health in Atlanta communities. The partnership delivers more personal support, pairing patients with community health workers who coordinate care and services.
A Georgia State University study found that Alzheimer's affects men's and women's brains differently, with women showing steeper and more widespread decline. The research suggests that brain compensation mechanisms may help maintain cognitive performance in women earlier in the disease.
A novel flu vaccine platform uses cell-derived extracellular vesicles to induce cross-protective immunity against influenza virus infections. The vaccine shows promise as an effective mucosal vaccine strategy.
Researchers found that metabolism of wheat fiber by intestinal bacteria generated bioactive anti-inflammatory metabolites, including polyphenols, which reprogrammed intestinal immune cells to suppress inflammation. The study suggests eating whole wheat foods may reduce one’s risk of developing inflammatory bowel disease (IBD).
Researchers from Georgia State University, Marcus Autism Center and Emory University are collaborating to investigate the causes of profound autism in children. The 7,500 child study will explore patterns in development, behavior, brain activity and genetics to find more effective therapies.
Researchers at Georgia State University found that segmented filamentous bacteria (SFB) provide marked protection against post-influenza bacterial pneumonia in mice. SFB reprograms alveolar macrophages to resist influenza virus-induced dysfunction, maintaining their defense against respiratory bacterial pathogens.
A new survey of over 2,000 K dwarfs, close to the Sun, has identified promising locations for life. These 'K dwarf' stars offer a long-term, stable environment for planetary companions, making them ideal candidates for supporting life.
Researchers used the CHARA Array to image two stellar explosions, Nova V1674 Herculis and Nova V1405 Cassiopeiae, providing direct evidence of multiple outflows and delayed expulsion. The images reveal unprecedented complexity in novae, with dramatic delays in ejection process.
A breakthrough study from Georgia State University links brain biology to behavior, revealing the long-sought bridge between micro- and macro-level brain organization. The research team uncovered a detailed biological map connecting different levels of the brain, shedding light on how molecular features influence cognition.
Cynthia Nau Cornelissen has received nearly $7 million in federal grants to combat sexually transmitted infections (STIs), particularly gonorrhea. The researcher will study the human-specific pathogen Neisseria gonorrhoeae and develop vaccines and therapeutics using innovative approaches.
Researchers Andrew Gewirtz and Lanying Du from the Institute for Biomedical Sciences at Georgia State University have been recognized as Highly Cited Researchers in 2025. They are among the top 1% of globally impactful researchers, with highly cited papers in multiple fields.
Researchers found that a plant-based diet prevented the development of coronary microvascular dysfunction (CMD) and reversed established CMD in hypertensive rats. The diet improved function of blood vessel cells, counteracting the damaging effects of hypertension.
Nagur Shareef Shaik's AI-powered data intelligence platform PRISM automates data workflows through automation, transparency and ethical AI integration. It empowers users to get critical insights from their data securely and instantly without needing programming expertise.
A Georgia State University researcher has received a $25,000 grant to develop mechanisms for treating obesity and related metabolic dysfunctions. The goal is to identify therapeutic candidates with strong clinical translation capabilities.
DZ-002 is an innovative cancer treatment developed through a collaborative effort among Georgia State University, Emory University and Cedars-Sinai Medical Center. The technology harnesses targeted radiation to destroy tumors with precision, offering hope for improved patient outcomes.
The CHARA Array will be upgraded with state-of-the-art optics and controllers, enabling simultaneous observations across visible and near-infrared wavelengths. This advancement will allow researchers to explore the universe in unprecedented detail, from local star systems to distant galaxies.
Researchers used CRISPR gene editing to bring back a human lost gene that breaks down uric acid, a waste product causing gout and related health issues. The study showed promising results in lowering uric acid levels and preventing fat buildup in liver cells.
The TReNDS Center has received two new NIH-funded R01 grants aimed at tackling Alzheimer's disease progression and advancing multimodal brain imaging techniques in neuropsychiatric disorders. The center will develop flexible models to link data and uncover complex patterns in neuroimaging and genomics.
The CHARA Array has enabled groundbreaking discoveries about stars, including the massive star Regulus and binary star systems. With new capabilities, the array will continue to reveal secrets about stars, planetary systems, and distant supermassive black holes.
A study by Georgia State University researchers found that a novel mucosal adjuvant enhances protection against various influenza virus challenges. The adjuvant, derived from mature bone marrow-derived dendritic cells, elicited significant and cross-reactive immune responses in mice.
Claire Zhou, a rising senior from Northview High School, won the 2025 USA Brain Bee National Championship and will represent the United States at the International Brain Bee World Championship. She was crowned champion after successfully completing three rounds of competition focused on human brain and brain disorders.
Dr. Krause's pioneering work on neural circuits and internal body sensing has led to two pivotal studies illuminating the complex interactions between stress, neural circuitry, and the heart-gut axis. His research holds therapeutic promise for advancing treatments for obesity, hypertension, and other cardiometabolic diseases.
A research team led by Professor Leslie Wolf aims to increase participation in biomedical studies by empowering participants as co-researchers. The study, funded by PCORI, will investigate the impact of participant involvement on study designs and methods.
Three Georgia State University professors are recognized as Innovators of the Year for their transformative contributions to mental health, stroke recovery, and dementia care. Amanda Gilmore's technology innovations help prevent violence against women, while Russell Jeter's robotic device assists stroke patients in their recovery at home.
Associate Professor Elizabeth Tighe at Georgia State University has received the Presidential Early Career Award for Scientists and Engineers, recognizing her exceptional potential for leadership in research. Her work focuses on adult literacy, developing instructional materials and interventions to support adults with reading challenges.
A team of researchers at Georgia State University has identified a novel group of neurons controlling the brain-heart-gut axis that can be activated to induce a hypometabolic state resembling hibernation. This discovery could have wide-ranging impacts on scientific fields, including obesity and cardiometabolic health.
The nine-story Research Tower will provide state-of-the-art facilities for research and innovation, fostering collaboration and driving economic growth in the region. The facility represents a crucial step forward in Georgia State's strategic commitment to placemaking efforts in downtown Atlanta.
Dr. Debra Bangasser has received the Daniel H. Efron Research Award for her contributions to understanding stress response mechanisms and sex differences in brain function. Her research aims to improve women's health and treatment outcomes for psychiatric disorders.
A team of researchers at Georgia State University has made a groundbreaking discovery in understanding schizophrenia using fMRI scans. They identified unique spatial variation and enhanced sensitivity in the brains of patients with schizophrenia, offering an alternative way to identify early signs of the disorder.
DZ-002 delivers anticancer drugs exclusively to cancer cells using a cancer-targeting dye carrier, improving tumor diagnosis, detection, and treatment. The technology aims to enhance patient survival rates and quality of life.
A new study highlights how environmental factors can impact mental health, cognition, and brain development in young people. Researchers analyzed satellite-based observations and neuroimaging data to identify associations between urban environment and mental health outcomes.
A researcher at Georgia State University has received a grant to evaluate the therapeutic potential of a new small molecule in obesity-linked diabetic models. The study aims to assess the efficacy and mechanisms of this new molecule in improving pancreatic islet cell function and mitigating adiposity.
The National Science Foundation grant enables global access to the CHARA Array, a powerful tool for milliarcsecond imaging research. This facility has already led to groundbreaking discoveries, including high-resolution images of stars and supermassive black holes.
A recent study suggests that starting antiviral treatment as late as 14 days after COVID-19 infection can still provide benefits for immunocompromised patients. The research found that drugs like paxlovid and molnupiravir can inhibit virus replication, even if initiated up to 14 days after infection.
Researchers at Georgia State University have developed a new approach to finding life beyond Earth by focusing on the most abundant type of star in the universe: M dwarfs. With their vast resources and potential for habitable planets, M dwarfs offer the best chance for scientists to discover life-supporting exoplanets.
Researchers found that certain gut bacteria, such as Clostridium perfringens, can hinder the efficacy of the rotavirus vaccine. This study suggests that microbiota composition plays a role in immune responses elicited by rotavirus vaccines.
Astronomers using Georgia State University's CHARA Array have identified large spots on the surface of Polaris, also known as the North Star. The observations provided the first glimpse of what the surface of a Cepheid variable looks like, revealing a diameter 46 times larger than the Sun.
A team of researchers has discovered novel and unexpected phenomena when studying fractional quantum Hall effects in flatland systems. By applying a supplementary current to high mobility semiconductor devices, they were able to explore new non-equilibrium states of these quantum systems and reveal entirely new states of matter.