A recent study found that carboxymethylcellulose, a widely used food additive, alters the intestinal environment of healthy individuals by reducing beneficial bacteria and nutrients. The research suggests that long-term consumption of this additive may promote chronic inflammatory diseases, highlighting the need for further study.
A team of researchers at Georgia State University has created a lightning-fast computer software that can process over 200,000 novel virus genomes in under two hours. The software provides valuable information for countries making early decisions about lockdowns, quarantines, and testing during infectious disease outbreaks.
A study led by Georgia State University researchers found that increased salt intake can lead to a decrease in blood flow to the hypothalamus, a key region for regulating body functions. This 'inverse neurovascular coupling' mechanism may play a role in hypertension and could have implications for developing new treatments.
A modified version of remdesivir, a COVID-19 treatment, has shown high effectiveness in suppressing SARS-CoV-2 replication and transmission when given orally. The study found that the oral prodrug could be a powerful tool for healthcare workers to combat highly infectious variants.
Researchers at Georgia State University found that vibration training improved both physical and cognitive abilities in adults with MS. Cognitive function improvements included enhanced memory capacity and executive function.
Researchers create red biosensor R-CatchER that directly monitors calcium activity at specific locations within a cell, aiding in understanding molecular basis of human diseases. The discovery could aid in better understanding of disease mechanisms and development of new drug discovery tools.
Researchers at Georgia State University found that singing and imagining improvised music elicits the same flow-like brain states as when musicians are actually performing. The study used fMRI data to identify how a musician's brain reconfigures connectivity depending on the degree of creativity required during jazz performances.
Researchers at Georgia State University have been awarded a $3.3 million grant to study a novel behavioral intervention targeting binge drinking and sexual assault among college students, tailored by gender and sexual orientation. The program, Positive Change (+Change), has shown promising preliminary efficacy in pilot studies and aims...
A public health researcher at Georgia State University has received a federal grant to develop a mental health awareness training program for adults who interact with youth. The program aims to increase community capacity to identify mental health concerns and improve access to services.
The Georgia State University's National Center for Sexual Violence Prevention aims to reduce violence in high-risk populations. Researchers will focus on evidence-based interventions and study real-world implementation of accessible interventions.
The National Center on Child Trafficking (NCCT) will develop and disseminate effective practices to improve outcomes for CSEC/T youth and their families. The center will also train mental health therapists in evidence-based treatments to address these issues.
A biomedical sciences researcher is studying the impact of environment on gut microbiota, immunity, and inflammation in a novel mouse model system. The goal is to define changes in the gut microbiota and mucosal immune system in relation to intestinal inflammation and colon cancer.
Georgia State University researcher Vince Calhoun has received a $3.5 million grant to develop new methods for capturing dynamic connectivity in the brain and identifying biomarkers for early detection of Alzheimer's disease. The researchers aim to analyze real-time connectivity patterns to predict future cognitive decline.
A recent study found COVID-19 survivors exhibit abnormal patterns of brain connectivity associated with increased post-traumatic stress symptoms. The research team discovered three distinct states of functional connectivity in the brains of COVID-19 survivors, which are linked to symptom severity.
A study by Georgia State University researchers found a significant increase in physical and psychological aggression among couples during the pandemic. Rates of aggression rose sharply after shelter-in-place restrictions were implemented, with non-heavy drinkers being disproportionately affected.
Dr. Christopher Basler received two NIH grants totaling $816,534 to study Middle East respiratory syndrome (MERS) coronavirus and SARS-CoV-2. The research aims to understand how these viruses interact with the body's immune response and identify potential new strategies for treating infection.
A study published in The EMBO Journal identified several host proteins that interact with the Ebola virus protein VP30, inhibiting viral transcription and replication. These findings suggest a novel target for preventing Ebola virus infection, providing potential new therapeutic strategies.
Researchers identified compounds that target VPS34 and fatty acid metabolism as potent inhibitors of SARS-CoV-2 replication. These findings reveal critical pathways involved in the virus's life cycle, providing novel insights for developing therapeutics targeting these pathways.
Researchers at Georgia State University have developed an oral prodrug that delivers carbon monoxide via artificial sweeteners, showing promise in treating acute kidney injury. The study demonstrates the protective effects of CO against organ damage and suggests potential applications for transplantation and other conditions.
A new universal vaccine may improve cross protection against different flu virus strains in adults and seniors with pre-existing immunity. The grant aims to test this theory in aged populations, addressing a significant public health concern.
A study by Georgia State University's Taylor Shelton found that vacant gameday homes drive up housing prices, displacing permanent residents in small college towns. The study analyzed data from over a dozen college towns and suggests changes to zoning and tax laws could ease the impacts.
Research from Georgia State University psychology researchers shows that twins produce fewer gestures and use language less than their singleton peers. However, when one child lags behind in gesture, the other tends to lag as well, suggesting a close link between gesture and speech in early development.
Researchers developed an intranasal influenza vaccine using recombinant hemagglutinin and found it enhanced immune responses in mice. The vaccine showed superior immunoenhancing properties and conferred protection against both same and different virus strains.
A new study published in PLOS Pathogens found that mice fed a Western-style diet high in processed foods and low in fiber developed persistent infections that led to inflammation and insulin resistance. The researchers suggest that altering gut microbiota through diet may be a means of promoting health.
A Georgia State University professor has received a $2.3 million grant to investigate the role of inflammation in otitis media, an infection of the middle ear. The goal is to develop novel anti-inflammatory therapeutics and improve hearing outcomes.
Researchers are investigating how oxytocin and dopamine act in the brain's reward circuits to make social interactions rewarding for males and females. The project has the potential to provide new mechanisms for understanding well-known sex differences in neuropsychiatric disorders and spur the development of gender-specific treatments.
Georgia State University researchers have received a five-year, $3 million grant to develop new strategies for identifying mood disorders using whole brain dynamics. The team will integrate four-dimensional brain imaging with clinical and cognitive data to identify clues about how mental illness presents in the brain.
A new radon gas measurement system will measure radon continuously in DeKalb County, helping builders plan mitigation efforts ahead of time. The system could be deployed globally to assess risk and determine hazard in underground mining operations.
A study led by Georgia State University researchers found that residents with dementia in assisted living facilities benefit from being included in activities and having caregivers meet them where they are. This approach improves quality of life for individuals with varying types of dementia and levels of functional ability.
A four-year federal grant of over $2 million is being awarded to Dr. Andrew Gewirtz at Georgia State University to investigate the role of inflammation and altered gut microbiota in the development of metabolic syndrome.
The National Cancer Institute funded a 5-year grant to integrate two evidence-based programs: Some Things are Better Outside and SafeCare. The goal is to eliminate child secondhand smoke exposure and reduce cancer risk among families involved with child protection services.
A $400,000 NSF grant will support a five-year project investigating the role of formal and informal social relationships among officers in shaping police behaviors. The findings aim to reduce police misconduct by informing policy initiatives and educational training programs.
A new drug, ProAgio, has been shown to be effective in treating pancreatic cancer and prolonging survival in mice. It works by inducing apoptosis in cancer-associated fibroblasts, reducing the dense stroma that protects tumors from immune systems and conventional drugs.
Researchers found that COVID-19 infects the brain, leading to severe illness, even after lungs clear themselves of the virus. The study suggests that brain damage is a key factor in long-term health problems and increased risk of future diseases.
Researchers found state shutdown orders and economic factors had a greater impact on initial unemployment claims during the first six weeks of the pandemic. State responses to COVID-19, such as closing non-essential businesses, were more influential than federal programs like CARES Act legislation.
A new study published in Nature Communications found that deep learning models surpass standard machine learning approaches in analyzing brain imaging data, generating more accurate representations of the human brain. This is particularly beneficial for complex problems requiring large datasets and advanced analysis.
Georgia State University and Emory University collaborate to train nursing home staff in innovative telementoring model to prevent SARS-CoV-2 spread. The ECHO model provides virtual community of learners, sharing best practices and knowledge on infection control, care for asymptomatic residents, and reducing social isolation.
A recent study published in Scientific Reports found that both capuchin monkeys and rhesus macaques exhibit the sunk cost phenomenon, persisting longer than optimal when uncertain about outcomes. This behavior is driven by evolutionary mechanisms and uncertainty, suggesting it may be deeply embedded across species.
Researchers found that brains work harder to process motion descriptions in unfamiliar languages, a phenomenon known as the P600 effect. This study, published in Neuropsychologia, suggests that language influences how our brains perceive and interpret physical movement.
A new antiviral drug, MK-4482/EIDD-2801, completely suppresses virus transmission within 24 hours, according to Georgia State University researchers. The drug is potent against influenza viruses and has broad-spectrum activity against respiratory RNA viruses.
A new NSF-funded project at Georgia State University will examine the operation of illicit supply chains used for virtual products and services. The research team will generate low-cost but powerful tools to counter online offenders and provide empirical evidence to inform policy and law enforcement interventions.
The Georgia State University research team is developing a program called BE WITH to reduce social isolation and elevated suicide risk in racially diverse older adults. They will evaluate the effectiveness of the training for nutrition service volunteers who work with old adults in six metro Atlanta counties.
Georgia State University researchers have developed a software tool called COINSTAC, which allows for local data analysis and sharing of results, protecting patient privacy and anonymity. The platform is designed to be compatible with deep learning models, enabling the training of analyses on decentralized databases.
A global study has identified common vulnerabilities among three lethal coronaviruses, including frequently hijacked cellular pathways. The study highlights shared cellular processes and protein targets that could be considered as targets for therapeutic interventions.
A start-up company led by Georgia State University chemist Jenny Yang has received a National Institute of Health grant to accelerate development of an MRI contrast agent that can non-invasively detect early-stage liver disease. The agent works by binding with collagen, alerting clinicians to the presence of fibrosis.
Biomedical researchers at Georgia State University have identified a novel method for eradicating rotavirus and other viral infections using interleukin-18 and interleukin-22. The study shows that these cytokines can rapidly and completely eliminate viruses from intestinal epithelial cells, even in compromised immune systems.
A team of Georgia State scientists aims to use fMRI data to help psychiatrists predict response to medication, potentially reducing the time it takes to receive an accurate diagnosis and get on the right treatment. The tool has shown over 90% accuracy in predicting medication outcomes on previous data sets.
Dr. Leszek Ignatowicz is studying the impact of intestinal microbiota on immunosenescence, a condition that causes the immune system to decline with age. His research aims to develop new strategies to control gut inflammation and enhance immune function in older individuals.
The CHARA Array, the world's largest optical interferometer, has received $7.1 million to fund a new mobile telescope and expand its open-access program for scientists. The new telescope will increase the array's diameter to over one kilometer and provide the highest resolution of any instrument in the world.
Researchers are combining different types of brain imaging data to capture patterns indicative of brain disorders. The goal is to develop a compact framework to map brain disorders, providing a signature that tells us how mental illnesses impact the brain.