Researchers at Georgia State University found that segmented filamentous bacteria in the gut protect mice from severe respiratory viral infections. The study showed that this bacterial species alters immune cells in the lungs to resist infection, with potential implications for human diseases like COVID-19.
Two new studies by experts at Georgia State University's TReNDS Center highlight the potential of brain imaging to identify biomarkers for cognitive developments and psychiatric issues in adolescent brains. The research team analyzed functional network connectivity across scans and found associations with various health measures, inclu...
The center will establish a national presence in cutting-edge research areas like Human-AI Collaboration and Responsible AI. Researchers aim to develop natural language interfaces for robots like Boston Dynamics' Spot, increasing its useful tasks and navigating environments on its own.
Researchers have developed an oral lipid nanoparticle drug that prevents tumor development in mice, demonstrating its potential as a treatment for colitis-associated cancer. The study, led by Georgia State University researchers, used M13-loaded nanoliposomes to target diseased tissue and reduce side effects.
A $2 million grant from the National Science Foundation will support research on developing tools to help landowners plan controlled burns more effectively. The project aims to create a cloud-based platform that simulates burn plans, using satellite and weather data to predict fire spread and duration.
Researchers found that molnupiravir efficiently blocked SARS-CoV-2 transmission when administered at a human effect size-equivalent dose, but paxlovid did not. The study used ferret animal models and found that molnupiravir completely suppressed transmission at all tested doses.
Researchers have identified age-related changes in brain patterns associated with schizophrenia risk using a new hybrid, data-driven method. The study found alterations in prefrontal-sensorimotor and cerebellar-occipitoparietal brain connections linked to genetic risk for schizophrenia.
Dr. Jun Zou's research aims to explain how diabetes causes heart disease and develop approaches to prevent it. He investigates the role of gut microbiota in cardiac dysfunction, with potential therapeutic strategies for maintaining a healthy intestinal-microbiota relationship.
A novel protein nanoparticle vaccine candidate using adjuvants has been developed to boost effectiveness against viral infections. The study found that the vaccine provided complete protection against influenza viral challenges.
Researchers at Georgia State University found that psyllium fiber protects against ulcerative colitis by activating the bile acid nuclear receptor FXR, which suppresses inflammation. The study suggests that pharmacologic activation of FXR might be useful in managing inflammatory bowel disease.
A study by Georgia State University researchers identifies common techniques and forms of deception used by scammers to target victims on dating apps. The team analyzed nearly 10,000 vetted reports to develop a model for victim vulnerability and resilience.
A new study published in Cell Host & Microbe found that mice offspring from fiberolean mothers gained striking amounts of weight when fed a Western-style diet. The research suggests that microbial diversity plays a crucial role in obesity development, and that fiber is only beneficial if it's metabolized by beneficial bacteria.
Tricia King's project aims to create personalized treatment plans for brain cancer survivors by identifying environmental, clinical, and genetic risk factors. The research has the potential to improve treatment outcomes for patients with various types of cancer.
Researchers detected a long-sought after innermost dusty ring around the type 1 active galactic nucleus (AGN) NGC 4151 with unprecedented clarity. The CHARA Array Interferometer achieved this milestone by resolving the dust sublimation region at a hundred microarcsecond scale.
A self-guided app, 'Nna le wena,' provides structured activities to encourage caregiver-child communication and can be implemented into daily routines. The study found modest progress in children's communication skills, with over half of caregivers reporting significant improvements.
Dr. Cynthia Nau Cornelissen receives $4.9 million NIH grant to explore Neisseria gonorrhoeae metal transporters that disrupt nutritional immunity, a key process preventing microbial growth and infectivity. The research aims to develop new therapeutics against 'superbug' strains and potentially create a protective vaccine.
Researchers at Georgia State University have discovered a way to prevent and treat gonorrhea by generating a mutation in a key molecule. The study found that inhibiting the bacterial pathogen's ability to hijack human immunity proteins could block gonorrhea infection.
A new study by Georgia State University researcher Judd Thornton finds that interviewers' assessments of respondent political knowledge are more closely correlated with interviewer race than factual accuracy. This bias affects Black respondents, who are rated as less knowledgeable even when controlling for objective performance. The re...
Researchers at Georgia State University have discovered a novel way to treat ulcerative colitis using lipid nanoparticles that target the colon with nucleic acids. The treatment showed accelerated healing and reduced inflammation in mice with acute colitis, offering a new gene therapy strategy for IBD treatment.
Researchers at Georgia State University have developed a single, universal flu vaccine candidate that induces immunity to conserved M2 ectodomain and multi-subtype neuraminidase proteins, providing broad cross-protection against antigenically diverse influenza A and B viruses in mice. The study shows promising results in young and aged...
Molnupiravir's efficacy is affected by SARS-CoV-2 variant type and biological sex of patients, according to the study. The drug showed variable results in dwarf hamsters infected with omicron, but was more effective in males than females.
Researchers from Georgia State University developed an AI model that can analyze large amounts of brain imaging data to identify novel patterns linked to mental health conditions. The model was trained on datasets of over 10,000 individuals and showed promise in predicting Alzheimer's disease, schizophrenia, and autism risk.
A study by Georgia State University researchers found that frequent video game players exhibit superior sensorimotor decision-making skills and increased brain activity compared to non-players. The study suggests that video games can be used for training in perceptual decision-making, with no trade-off between speed and accuracy.
A new universal influenza B vaccine protects against different strains and offers robust and sustained cross-immune protection. The double-layered protein nanoparticle vaccine is constructed with a stabilized portion of the influenza virus and induces broadly reactive immune responses.
Researchers have uncovered thousands of artifacts along Mexico's Yucatán Peninsula, shedding new light on the ancient Maya people who lived in a dynamic interplay between social and natural processes. The project has provided valuable insights into how the Maya adapted to environmental changes, such as rising sea levels, and offers a m...
Researchers at Georgia State University developed a universal flu vaccine offering broad cross-protection against different strains and subtypes of influenza A viruses. The vaccine, using M2e-stalk protein genetic fusion, induces immunoglobulin G antibodies and protective cellular T cell immunity in mice.
Researchers at Georgia State University developed a personalized treatment to prevent ulcerative colitis in mice by modifying gut microbiota. The study found that orally administering metabolites from treated microbiota provided strong protection against chronic inflammation.
The study found that the Omicron variant led to less severe disease with lower mortality rates compared to other variants like Alpha, Beta, and Delta. The researchers observed a significant decrease in virus levels, lung inflammation, weight loss, and mortality rate in mice infected with the Omicron variant.
Researchers at Georgia State University have identified an oral antiviral drug, AVG-388, that effectively blocks RSV's RNA polymerase, a key target for replication. The study demonstrates potent antiviral activity in animal models and human airway epithelium organoid cultures.
Researchers at Georgia State University have been awarded over $6 million to develop antiviral drugs targeting COVID-19 and other viral threats. The funding will support the establishment of a new Midwest Antiviral Drug Discovery Center, which aims to build a pipeline of antiviral drugs.
A recent study published in Frontiers in Psychology found that judges give significantly shorter sentences when provided with the full costs and benefits of incarceration. The research team from Georgia State University recruited 87 Minnesota state judges who were given a fictional case summary with additional details on the negative c...
Researchers at Georgia State University developed a nanoparticle vaccine combining two proteins that induce immune responses against SARS-CoV-2. The vaccine shows potential for broader and safe protection with robust ADCC activity and sustained immunity.
A team of Georgia State researchers used CRISPR-Cas9 technology to eliminate the Avpr1a receptor in hamsters, leading to unexpected changes in their social behavior. The study found that knocking out the receptor increased social communication behaviors and eliminated sex differences in aggression.
Researchers create biomimetic artificial vision device using nanotechnology to advance color recognition and scalability. The new device enables micro-scale cameras for microrobots, opening up possibilities in medical diagnosis, environmental study, manufacturing, and archaeology.
A new study found that e-cigarette use significantly increases adolescents' risk of cannabis use, especially among those with externalizing mental health problems. However, for those with internalizing mental health issues, the relationship is reversed, and they are less likely to begin using cannabis.
A study by Georgia State University researchers found that monkeys can 'choke under pressure' on a computerized matching task. The team discovered that individual variations in stress response and cortisol levels affect performance, suggesting an evolutionarily common trait among species.
Researchers found that massive stars can be far from their birthplace due to mergers of medium-mass stars. The study of HD93521 and IT Librae reveals that these stars can rotate quickly enough to create black holes with large spins.
A new intranasal flu vaccine constructed with nanoparticles has been shown to offer strong protection against different influenza virus strains in mice. The vaccine elicited multifaceted immune responses, leading to robust cross-protection and long-lasting defense.
A new study by Georgia State University reveals that COVID-19 traumatic stress may predict post-traumatic stress disorder (PTSD) symptoms, especially in individuals with a history of past trauma. The findings showed a positive association between COVID-19 traumatic stress and PTSD symptoms across racial groups, except for Asian Americans.
Researchers at Georgia State University found that newer variants of SARS-CoV-2 can infect the respiratory tract of wild mice, replicating in their lungs. This evolution highlights the virus's ability to mutate and spread in rodents living near humans.
A new study reveals significant variability in state- and nationwide policies on end-of-life decision making in US prisons. The researchers found that many policies restrict access to advance care planning documents, limit the roles of surrogate decision-makers, and fail to ensure compliance with community standards. The study emphasiz...
Georgia State University researchers discover how crowds can make bridges unstable due to tiny vibrations from each person walking, which can be amplified significantly. The new insights will help engineers and bridge designers build safer structures.
Researchers at Georgia State University have developed a new candidate antiviral drug, 4’-FlU, which shows potent activity against SARS-CoV-2 and other respiratory RNA viruses. The study demonstrates that 4’-FlU induces termination of the viral polymerase, aborting replication and offering a strong therapeutic asset.
A recent study found that carboxymethylcellulose, a widely used food additive, alters the intestinal environment of healthy individuals by reducing beneficial bacteria and nutrients. The research suggests that long-term consumption of this additive may promote chronic inflammatory diseases, highlighting the need for further study.
A team of researchers at Georgia State University has created a lightning-fast computer software that can process over 200,000 novel virus genomes in under two hours. The software provides valuable information for countries making early decisions about lockdowns, quarantines, and testing during infectious disease outbreaks.
A study led by Georgia State University researchers found that increased salt intake can lead to a decrease in blood flow to the hypothalamus, a key region for regulating body functions. This 'inverse neurovascular coupling' mechanism may play a role in hypertension and could have implications for developing new treatments.
A modified version of remdesivir, a COVID-19 treatment, has shown high effectiveness in suppressing SARS-CoV-2 replication and transmission when given orally. The study found that the oral prodrug could be a powerful tool for healthcare workers to combat highly infectious variants.
Researchers at Georgia State University found that vibration training improved both physical and cognitive abilities in adults with MS. Cognitive function improvements included enhanced memory capacity and executive function.
Researchers create red biosensor R-CatchER that directly monitors calcium activity at specific locations within a cell, aiding in understanding molecular basis of human diseases. The discovery could aid in better understanding of disease mechanisms and development of new drug discovery tools.
Researchers at Georgia State University found that singing and imagining improvised music elicits the same flow-like brain states as when musicians are actually performing. The study used fMRI data to identify how a musician's brain reconfigures connectivity depending on the degree of creativity required during jazz performances.