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Science News for September 13, 2022


‘Years of life lost’ to unintentional drug overdose in adolescents spikes during pandemic

The COVID-19 pandemic has seen a significant increase in years of life lost to unintentional drug overdose among adolescents, with synthetic opioids like fentanyl contributing to the rising trend. Researchers found that mortality due to unintentional overdose in adolescents reached an all-time high in 2020.

SourceOhio State University Wexner Medical Center·JournalJournal of Adolescent Health·DateSep 13, 2022

‘Glass bubble’ nanocarrier boosts effects of combination therapy for pancreatic cancer

Researchers at California NanoSystems Institute developed a nanocarrier that delivers a combination therapy to pancreatic tumors using irinotecan and 3M-052, resulting in improved treatment outcomes and reduced side effects. The simultaneous delivery of the two drugs outperformed separate treatments in mouse models.

SourceCalifornia NanoSystems Institute·JournalACS Nano·TypeExperimental study·DateSep 13, 2022

Personalized prediction of depression treatment outcomes with wearables

Researchers developed a unified machine learning model that analyzes data from patients with and without treatment, predicting depression outcomes better than separate models. The approach enables personalized medicine by designing treatment plans specific to each patient's needs.

SourceWashington University in St. Louis·JournalProceedings of the ACM on Interactive Mobile Wearable and Ubiquitous Technologies·TypeRandomized controlled/clinical trial·DateSep 13, 2022

WPI researchers receive new funding for sustainable concrete substitute

Researchers aim to improve and expand Enzymatic Construction Material (ECM), a sustainable alternative to traditional concrete that can repair cracks and reduce greenhouse gas emissions. The grant will also support programs to inspire girls' interests in engineering and construction, addressing the industry's gender gap.

SourceWorcester Polytechnic Institute·JournalCell Reports Physical Science·TypeExperimental study·DateSep 13, 2022

Healthcare researchers must be wary of misusing AI

Healthcare researchers caution against misusing AI algorithms in clinical research, highlighting concerns about bias, transparency, and data quality. The team advocates for evaluating ML methods against traditional statistical approaches and ensuring clinician decision-making is complemented, not replaced.

SourceDuke-NUS Medical School·JournalNature Medicine·TypeCommentary/editorial·DateSep 13, 2022

COVID-19 amplified hardship for many Harvey victims

A recent study by Rice University, Notre Dame, and Environmental Defense Fund reveals that COVID-19 exacerbated the economic and mental health consequences of Hurricane Harvey. The research, which analyzed data from over 3,000 participants, found a distinct distinction between acute effects and secondary stressors.

SourceRice University·JournalEnvironmental Research·TypeSurvey·DateSep 13, 2022

The blood stem cell research that could change medicine of the future

Researchers at UNSW Sydney have made significant discoveries about embryonic blood stem cell creation that could one day eliminate the need for blood stem cell donors. Two studies have emerged from UNSW researchers in this area that shine new light on how precursors to blood stem cells occur in animals and humans, and how they may be i...

SourceUniversity of New South Wales·JournalCell Reports·TypeExperimental study·DateSep 13, 2022

Interviewers show racial bias when reporting survey respondents’ political knowledge

A new study by Georgia State University researcher Judd Thornton finds that interviewers' assessments of respondent political knowledge are more closely correlated with interviewer race than factual accuracy. This bias affects Black respondents, who are rated as less knowledgeable even when controlling for objective performance. The re...

SourceGeorgia State University·JournalThe Journal of Race Ethnicity and Politics·TypeData/statistical analysis·DateSep 13, 2022

Scientists have created a mathematical model for the dynamics of nanoparticles and viruses in cells

A team of scientists from Ural Federal University has developed a complex mathematical model to understand the dynamics of nanoparticles and viruses in cells. The model reveals how viruses cluster inside endosomes and interact with cellular proteins, shedding light on their behavior and replication mechanisms. This breakthrough can hel...

SourceUral Federal University·JournalCrystals·DateSep 13, 2022

New method to identify symmetries in data using Bayesian statistics

Researchers from Osaka Metropolitan University developed a new method to identify symmetries in multi-dimensional data using Bayesian statistics. This approach allows for the derivation of exact integral formulas and an efficient algorithm for searching symmetries, reducing parameters and samples required for genetic analysis.

SourceOsaka Metropolitan University·JournalThe Annals of Statistics·TypeComputational simulation/modeling·DateSep 13, 2022

Nanorattles shake up new possibilities for disease detection

Researchers at Duke University developed nanorattles that amplify signals from separate biomarkers, allowing for accurate detection of head and neck cancers without biopsies. The technology uses machine learning algorithms to tease apart multiple biomarker signals, making it possible to target multiple diseases simultaneously.

SourceDuke University·JournalJournal of Raman Spectroscopy·TypeExperimental study·DateSep 13, 2022

Insects struggle to adjust to extreme temperatures making them vulnerable to climate change, study finds

Researchers found that insects have a weak ability to acclimate to high temperatures, with only small compensations of 10-15°C. Juvenile insects show greater resilience, but this may be limited to specific critical periods. The study highlights the need for further research on insect responses to climate change.

SourceUniversity of Bristol·JournalNature Communications·TypeMeta-analysis·DateSep 13, 2022

US presidential narcissism linked to longer wars

A new study by Ohio State University researchers found that US presidents who scored high on a measure of narcissism spent an average of 613 days at war, compared to 136 days for those below average. Narcissistic leaders tend to extend wars to declare victory and maintain their self-image.

SourceOhio State University·JournalJournal of Conflict Resolution·TypeData/statistical analysis·DateSep 13, 2022

Oregon State researchers develop messenger RNA therapy for ovarian cancer, muscle wasting

Researchers at Oregon State University have developed a promising messenger RNA therapy for ovarian cancer, which also shows promise in treating cachexia, a muscle-wasting condition associated with cancer. The treatment uses lipid nanoparticles to deliver mRNA that triggers the production of the follistatin protein within cancer clusters.

SourceOregon State University·JournalSmall·TypeExperimental study·DateSep 13, 2022

Targeted travel restrictions fail to halt spread of COVID-19

A study in the Netherlands found that restricting flights from countries where COVID-19 variants of concern emerge is not enough to halt their spread. The researchers analyzed nearly 40,000 genome sequences and found that all four VOCs had already been introduced into the country by the time flight restrictions were implemented.

SourceeLife·JournaleLife·DateSep 13, 2022

Cowbird chicks do best with two warbler nest mates – not four, not zero, study finds

A new study reveals that Brown-headed cowbird chicks thrive when paired with two Prothonotary Warbler nestlings, while performing poorly with four or no nestmates. This strategic advantage is attributed to the cowbirds' ability to outcompete and manipulate their host environment.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalProceedings of the Royal Society B Biological Sciences·TypeExperimental study·DateSep 13, 2022

Where do high-energy particles that endanger satellites, astronauts and airplanes come from?

Scientists Luca Comisso and Lorenzo Sironi used supercomputers to simulate the origin of high-energy particles in turbulent environments like the sun's atmosphere. Their research provides a clear pattern of when and how these particles form, paving the way for more accurate predictions of space weather events.

SourceColumbia University·JournalThe Astrophysical Journal Letters·TypeComputational simulation/modeling·DateSep 13, 2022

Keep the beat!

Researchers found that male rock hyraxes with more precise courtship songs had higher reproductive success, while those who sang less frequently also performed better in terms of rhythm and song quality. This study suggests that high rhythmic stability may serve as an indicator of male quality for females.

SourceUniversity of Konstanz·JournalJournal of Animal Ecology·DateSep 13, 2022

Women’s mental well-being more sensitive to exercise than men’s during different stages of pandemic

A recent study by Binghamton University researchers found that women's mental health is more affected by physical exercise frequency during the COVID-19 pandemic. High exercise frequency often resulted in high levels of mental distress in women, contrasting with men, where frequent exercise was advantageous. The study suggests that wom...

SourceBinghamton University·JournalNutrients·DateSep 13, 2022

Study quantifies impact of human activity on Atlantic Rainforest’s carbon storage capacity

The study quantifies the impact of human activity on the Atlantic Rainforest's carbon storage capacity, highlighting that forest degradation leads to significant losses and increased greenhouse gas emissions. Conservation efforts are crucial to reverse these effects and protect the biome's carbon stocks.

Chinese Medical Journal review sheds light on protein drug target for treating non-alcoholic fatty liver disease

A review article suggests that retinol-binding protein-4 (RBP4) may be a potential target for clinical intervention in non-alcoholic fatty liver disease. The study highlights the importance of RBP4 in the pathogenesis of NAFLD, including its role in inducing hepatic de novo lipogenesis and impairing fatty acid oxidation.

SourceCactus Communications·JournalChinese Medical Journal·TypeLiterature review·DateSep 13, 2022

Immuno-oncology treatment pre-surgery safe and effective option for localized non-small cell lung cancer

A new study led by Ohio State University researchers found that atezolizumab is a safe and effective treatment option for stage IB-IIIB non-small cell lung cancer patients prior to surgery, with survival rates reaching 80% at three years post-treatment. The study also identified new blood markers that can help predict treatment response.

SourceOhio State University Wexner Medical Center·JournalNature Medicine·TypeExperimental study·DateSep 13, 2022

Specific sequence of drugs reduces cost of treating metastatic breast cancer while preserving quality of life

Researchers found that a specific sequence of drugs can reduce overall costs and improve the value of care for patients with metastatic breast cancer, while minimizing side effects. The study's results suggest that treatment sequencing approaches that minimize costs early may improve the value of care.

SourceUNC Lineberger Comprehensive Cancer Center·JournalJournal of Clinical Oncology·TypeComputational simulation/modeling·DateSep 13, 2022

Significant increase in suicide rates in women and younger age groups during the COVID-19 pandemic in Japan

A study by Hokkaido University researchers found a significant increase in suicide rates among women and younger age groups during the COVID-19 pandemic in Japan. Excess suicide deaths for men and women were recorded, with sub-group analyses revealing a positive correlation between increased mortality and specific age ranges.

SourceHokkaido University·JournalThe Lancet Regional Health - Western Pacific·TypeData/statistical analysis·DateSep 13, 2022

New approach to correct systematic errors in bottle data of ocean temperature

Researchers from the Institute of Atmospheric Physics develop a correction method for Nansen cast temperature profiles, addressing a depth bias affecting global ocean warming assessments. The new approach has significant implications for understanding ocean warming rates and achieving better climate understanding.

SourceInstitute of Atmospheric Physics, Chinese Academy of Sciences·JournalJournal of Atmospheric and Oceanic Technology·DateSep 13, 2022

Brothers and sisters shape character less than thought

A large-scale study of over 80,000 adults from nine countries found no systematic relationship between sibling gender and personality traits such as risk-taking or emotional stability. The results suggest that siblings have a limited influence on personality development in adulthood.

SourceUniversität Leipzig·JournalPsychological Science·TypeData/statistical analysis·DateSep 13, 2022

Counting cravings for coffee and soft drinks

A study by Flinders University found that stronger cravings for coffee and soft drinks are associated with increased consumption, especially for soft drinks. The study analyzed data from 128 participants aged 17-25 years old and found that water was the most craved beverage but not necessarily consumed more.

SourceFlinders University·JournalEating Behaviors·TypeSurvey·DateSep 13, 2022

Crops grown together cooperate better in just two generations

Researchers found that crops bred for single-species systems rapidly adapt to growing alongside multiple species, leading to increased cooperation and productivity. The study suggests breeding plants to grow in mixed-species plots may improve yields and reduce the need for fertilizers and other harmful practices.

SourceeLife·JournaleLife·DateSep 13, 2022

Leipzig hematologists research rare forms of blood cancer

Researchers at Leipzig University Hospital's Clinic and Polyclinic for Hematology discovered two new forms of rare blood cancers, including a molecular mechanism in T-lymphocytes that augments the response to incoming cell signals. The findings have significant implications for diagnosis, prognosis, and treatment planning.

SourceUniversität Leipzig·JournalNature Communications·TypeRandomized controlled/clinical trial·DateSep 13, 2022

Revealing one of the mechanisms by which thyroid cancer becomes resistant to lenvatinib-a molecularly targeted drug

A study found that activation of the epidermal growth factor receptor (EGFR)-mediated signaling pathway is involved in lenvatinib resistance in thyroid cancer cells. Inhibition of EGFR by lapatinib therapy in combination with lenvatinib enhanced growth inhibitory effect and inhibited tumor growth more remarkably than monotherapy.

SourceShinshu University·JournalCancer Science·TypeExperimental study·DateSep 13, 2022

Reaching national electric vehicle goal unlikely by 2030 without lower prices, better policy

A new study from Indiana University warns that the US is unlikely to reach its national goal of 50% plug-in electric vehicle penetration by 2030 unless electric vehicles become more affordable. The study suggests that lower prices and better policy are needed to stimulate consumer demand for affordable electric vehicles.

SourceIndiana University·JournalFrontiers in Environmental Science·TypeComputational simulation/modeling·DateSep 13, 2022

Researchers identify how science can help cities and companies to operate within Earth system limits

Researchers identified seven key knowledge gaps to help cities and businesses operate within Earth system limits, including developing common procedures and science-based targets. The report highlights the need for alignment of targets across domains to avoid tipping points and ensure a social justice dimension.

SourceUniversity of Exeter·JournalNature·TypeCommentary/editorial·DateSep 13, 2022

Nature vs. Laboratory: The differences between experimental evolution and natural adaptation

A new study finds that lab adaptation involves mutations to highly conserved proteins, but natural adaptation exhibits more complex patterns, including non-conservation within functional domains. Lab conditions differ significantly from natural environments with variable and changing selective pressures.

SourceSMBE Journals (Molecular Biology and Evolution and Genome Biology and Evolution)·JournalGenome Biology and Evolution·TypeObservational study·DateSep 13, 2022

Tumor-infiltrating B cells and plasma cells influence early-stage lung cancer biology, immunotherapy responses

A new study provides valuable insights into the roles of B cells and plasma cells in early-stage lung cancer biology, highlighting their influence on tumor development and treatment outcomes. The research also reveals environmental factors and molecular features that contribute to the landscape of infiltrating immune cells.

Tighter gestational diabetes control good for babies

A large study found that tighter gestational diabetes control reduced serious health problems and deaths in newborns, while increasing health risks for mothers. However, the exact causes of these increased risks remain unexplained, highlighting the need for further research.

SourceUniversity of Auckland·JournalPLOS Medicine·TypeRandomized controlled/clinical trial·DateSep 13, 2022

Erotophilia and sexual sensation–seeking are good predictors of engagement with sex robots, according to new research

A study by Simon Dubé examines the personality traits of people willing to engage with sex robots, revealing that erotophilia, sexual sensation-seeking, and enthusiasm for new experiences are key drivers. The research highlights an opportunity for manufacturers to cater to a female customer base as technology improves and becomes more ...

SourceConcordia University·JournalComputers in Human Behavior·TypeSurvey·DateSep 13, 2022

Building better quantum sensors

The new approach takes advantage of the way defects in diamonds or semiconductors behave like qubits, amplifying the information stored in solid-state defects. This discovery offers a significant improvement in sensitivity for quantum sensors measuring magnetic fields, temperature changes, and molecular structures.

SourceUniversity of Chicago·JournalPRX Quantum·DateSep 13, 2022

The rates of unique names increased in Japan over the 40 years from the 1980s: long-term analysis of baby names published in municipality newsletters

A new study analyzing baby names from municipality newsletters found rising trends of individualism in Japan, with unique names increasing from the 1980s to 2018. The research suggests a cultural shift towards greater uniqueness and independence.

SourceTokyo University of Science·JournalCurrent Research in Ecological and Social Psychology·TypeData/statistical analysis·DateSep 13, 2022

Walk then sit: A scientific recipe that helps babies stop crying

A new study published in Current Biology found that carrying crying infants for 5 minutes can promote sleep and reduce crying. The technique, known as the Transport Response, involves steady walking followed by sitting before laying the baby down to sleep. This method offers an immediate solution for parents of newborns struggling with...

SourceRIKEN·JournalCurrent Biology·DateSep 13, 2022

This fungus shrinks in size to better infect the brain

Scientists at University of Utah Health discovered that a fungus that causes fungal meningitis shrinks in size to better infect the brain. The 'seed' cells, which are smaller and have unique features, can colonize other organs and spread infection. Research suggests that phosphate may trigger this transformation.

SourceUniversity of Utah Health·JournalCell Host & Microbe·TypeExperimental study·DateSep 13, 2022